Abstract：
:Thioglycollate-stimulated, adherence and density gradient-enriched peritoneal exudate cells were used for the preparation of a specific, highly active antimacrophage reagent. After absorption with mouse lymphoid cells, an antimacrophage globulin (AMG) fraction was shown to be cytotoxic for peritoneal exudate macrophages but not spleen, lymph node or thymus cells. The AMG suppressed both the in vivo primary serum antibody and spleen PFC responses to KLH.
journal_name
Immunologyjournal_title
Immunologyauthors
Herscowitz HB,Diblasio RCkeywords:
subject
Has Abstractpub_date
1976-01-01 00:00:00pages
25-8issue
1eissn
0019-2805issn
1365-2567journal_volume
30pub_type
杂志文章相关文献
IMMUNOLOGY文献大全abstract：:The generation of effective immunity requires that antigen-specific T cells are activated, clonally expanded and ultimately eliminated by apoptosis. The involvement of CD95-mediated apoptosis in T-cell elimination is well established, but the conditions which regulate the death pathway under normal circumstances are s...
journal_title：Immunology
pub_type： 杂志文章
doi：10.1046/j.1365-2567.1999.00925.x
更新日期：1999-12-01 00:00:00
abstract：:There is much evidence to suggest that potentially immunogenic tumour cells can escape cytolytic immune destruction by loss of class I antigen expression. Many tumours are allele-specific class I negative and, in murine systems, reconstitution of class I expression by gene transfection leads to an increase in tumour i...
journal_title：Immunology
pub_type： 杂志文章
doi：
更新日期：1991-02-01 00:00:00
abstract：:Stimulated T lymphocytes and certain T-cell hybridomas secrete molecules capable of inducing B-lymphocyte proliferation and differentiation. It has been shown recently that one such B-cell stimulatory factor is associated with chondroitin sulphate proteoglycan (CSPG) and was designated T-cell proteoglycan fraction, or...
journal_title：Immunology
pub_type： 杂志文章
doi：
更新日期：1988-08-01 00:00:00
abstract：:An examination was made of the effects of eosinophilia on acute inflammation. Sprague Dawley rats were infected with Trichinella spiralis larvae which resulted in a blood eosinophilia. Groups of rats with the induced eosinophilia, and untreated rats without the eosinophilia, were treated with carrageenan, bradykinin o...
journal_title：Immunology
pub_type： 杂志文章
doi：
更新日期：1982-07-01 00:00:00
abstract：:Donor mice were painted on the skin of the abdomen with the contact sensitizing agent, oxazolone. One day later 2-5 x 10(6) cells from the regional lymph nodes were injected into the footpads of recipient mice. Contact sensitivity was detected 6 days later by challenging the ears of the recipients and measuring the in...
journal_title：Immunology
pub_type： 杂志文章
doi：
更新日期：1979-05-01 00:00:00
abstract：:Bovine Concanavalin A-induced suppressor cells were generated from lymphocytes which were non-adherent to anti-immunoglobulin coated dishes and cells possessing receptors for peanut agglutinin. Bovine lymphocytes, preincubated with 25 microgram/ml of Con A for 40-45 hr, could suppress the responses of autologous cells...
journal_title：Immunology
pub_type： 杂志文章
doi：
更新日期：1981-05-01 00:00:00
abstract：:Mitogen-activated protein/ERK kinase kinase 3 (MEKK3) is a Ser/Thr protein kinase belonging to the MEKK/STE11 subgroup of the MAP3K family. Recently, we found that MEKK3 plays a critical role in interleukin-1 (IL-1) receptor and Toll-like receptor 4 signalling using established primary mouse embryonic fibroblast (MEF)...
journal_title：Immunology
pub_type： 杂志文章
doi：10.1111/j.1365-2567.2006.02495.x
更新日期：2007-02-01 00:00:00
abstract：:Antigen-induced allergic airway inflammation is mediated by T helper type 2 (Th2) cells and their cytokines, but the mechanism that initiates the Th2 immunity is not fully understood. Recent studies show that basophils play important roles in initiating Th2 immunity in some inflammatory models. Here we explored the ro...
journal_title：Immunology
pub_type： 杂志文章
doi：10.1111/imm.12240
更新日期：2014-06-01 00:00:00
abstract：:In Trichinella spiralis-infected rats, a population of cells in thoracic duct lymph (TDL) that can adoptively transfer protection to naive rats was identified and characterized. During the course of T. spiralis infection, blast cells appeared in lymph from Day 3-4, and only Day 3-4 TDL cells had protective properties ...
journal_title：Immunology
pub_type： 杂志文章
doi：
更新日期：1987-06-01 00:00:00
abstract：:Bone marrow cells from mice were cultured in vitro in the presence of interleukin-3 (IL-3). After 2 weeks, the majority of the cells differentiated towards mast cells as judged by morphological and biochemical criteria. When populations of 99% IL-3-dependent mast cells (IL-3 MC) were tested for their anti-tumour activ...
journal_title：Immunology
pub_type： 杂志文章
doi：
更新日期：1985-06-01 00:00:00
abstract：:It has been reported that, in early pregnancy in mice, there is an increase in the number of immunoglobulin-secreting cells in the lymph nodes which drain the uterus. This paper describes the results of further investigations provoked by interest in these early changes. Increases in the numbers of immunoglobulin-secre...
journal_title：Immunology
pub_type： 杂志文章
doi：
更新日期：1985-06-01 00:00:00
abstract：:Natural killer (NK) cells, which can exert early and powerful anti-tumour and anti-viral responses, are important components of the innate immune system. DNAX accessory molecule-1 (DNAM-1) is an activating receptor molecule expressed on the surface of NK cells. Recent findings suggest that DNAM-1 is a critical regulat...
journal_title：Immunology
pub_type： 杂志文章,评审
doi：10.1111/imm.12516
更新日期：2015-11-01 00:00:00
abstract：:Thrombomodulin is a transmembranous glycoprotein of endothelial cells. In vitro it is a marker of endothelial cell injury. In vivo the levels of serum thrombomodulin are regarded as a parameter of activity in vasculitides. The latter are pathophysiologically determined by neutrophil-derived inflammation and endothelia...
journal_title：Immunology
pub_type： 杂志文章
doi：10.1046/j.1365-2567.2002.01469.x
更新日期：2002-11-01 00:00:00
abstract：:Control of resistance to cyst burden following per-oral infection with Toxoplasma gondii has been mapped previously to a region of mouse chromosome 17 of approximately 140 kb. This region is contiguous with and contains the class I gene, Ld. Resistance to development of toxoplasmic encephalitis has also been reported ...
journal_title：Immunology
pub_type： 杂志文章
doi：
更新日期：1995-07-01 00:00:00
abstract：:Anti-human milk fat globule membrane monoclonal antibodies HMFG-1 and HMFG-2 recognize epitopes within the protein core of human polymorphic epithelial mucin (PEM). These have been identified as PDTR and DTR, respectively. Using the solid phase synthesis of immobilized tetrameric peptides, we have systematically inves...
journal_title：Immunology
pub_type： 杂志文章
doi：
更新日期：1991-08-01 00:00:00
abstract：:Thoracic duct lymphocytes (TDL) from (AS2 x AS)F1 rats previously injected with human serum albumin (HSA) were transferred to 900 r irradiated syngeneic recipients which were challenged with various doses of soluble HSA (s-HSA). TDL from partially tolerant rats, which were deficient in high avidity B cells, produced a...
journal_title：Immunology
pub_type： 杂志文章
doi：
更新日期：1977-10-01 00:00:00
abstract：:Isolated human mononuclear cells were fractionated according to their membrane characteristics or physical properties. Adherent cells were depleted by filtration through glass columns; phagocytic cells were removed by iron treatment and cell subpopulations capable of forming rosettes with sheep erythrocytes (E), eryth...
journal_title：Immunology
pub_type： 杂志文章
doi：
更新日期：1976-03-01 00:00:00
abstract：:Among their diverse roles as transcriptional regulators during development and cell fate specification, the RUNX transcription factors are best known for the parts they play in haematopoiesis. RUNX proteins are expressed throughout all haematopoietic lineages, being necessary for the emergence of the first haematopoie...
journal_title：Immunology
pub_type： 杂志文章,评审
doi：10.1111/imm.12535
更新日期：2015-12-01 00:00:00
abstract：:Human plasma kallikrein can replace factor D for the activation of the alternative pathway C3 convertase of human complement. The factor B cleavage patterns by factor D and kallikrein are indistinguishable. The ability of kallikrein to cleave factor B is influenced by the magnesium ion concentration and the C3b concen...
journal_title：Immunology
pub_type： 杂志文章
doi：
更新日期：1982-03-01 00:00:00
abstract：:Interleukin-3 activity is produced by T cells at an early phase after antigenic stimulation, and its quantitation provides a sensitive and non-destructive method for assaying T-cell activation. It can be detected before increased uptake of [3H]thymidine into DNA occurs, and is more sensitive than measuring [3H]thymidi...
journal_title：Immunology
pub_type： 杂志文章
doi：
更新日期：1987-12-01 00:00:00
abstract：:Excessive and dysregulated inflammation is known to contribute to disease progression. HSP90 is an intracellular chaperone known to regulate inflammatory processes including the NLRP3 inflammasome and secretion of the pro-inflammatory cytokine interleukin(IL)-1β. Here, primarily using an in vitro inflammasome ASC spec...
journal_title：Immunology
pub_type： 杂志文章
doi：10.1111/imm.13267
更新日期：2021-01-01 00:00:00
abstract：:CD45 has been recognized as an important player in regulating signalling in lymphocytes. However, compared with tyrosine kinases, phosphatases are still poorly understood in terms of the details of their specificity and regulation. Here, the recent progress in understanding the biology of the first recognized receptor...
journal_title：Immunology
pub_type： 杂志文章,评审
doi：10.1111/j.1365-2567.2005.02265.x
更新日期：2006-02-01 00:00:00
abstract：:The effect on murine immunoglobulin G (IgG) glycosylation of altering IgG production in vivo was assessed in interleukin (IL)-6 transgenic and CD4 knockout mice. C57BL/6 mice carrying the IL-6 transgene showed increased levels of circulating IgG. This was associated with decreased levels of galactose on the IgG oligos...
journal_title：Immunology
pub_type： 杂志文章
doi：10.1046/j.1365-2567.1999.00896.x
更新日期：1999-11-01 00:00:00
abstract：:C57Bl/6 (B6) mice produced highly developed granulomata in the lung 3 or 4 weeks after intravenous injection with oil-associated BCG cell walls (CW), but C3H/He (C3H) mice did not. The potential to develop granulomata is genetically controlled (Yamamoto & Kakinuma, 1978). It is probable that the genes control only T-c...
journal_title：Immunology
pub_type： 杂志文章
doi：
更新日期：1981-05-01 00:00:00
abstract：:In two consecutive studies, eighteen and forty-one normal subjects were given a standard tuberculin skin test of 1 tuberculin unit (0.02 mug of PPD). Two days later another skin test was given. Readings of the skin reactions showed that subjects exhibiting strongly positive skin reactions in their primary skin tests s...
journal_title：Immunology
pub_type： 杂志文章
doi：
更新日期：1975-02-01 00:00:00
abstract：:The influence of changes of the cation-transporting activity of the membrane Na,K ATP-ase of human peripheral blood lymphocytes on their ability to form 'early' and 'late' rosettes with SRBC was investigated. It was shown that inhibition of the Na,K ATP-ase-dependent cation transport through the lymphocyte membrane by...
journal_title：Immunology
pub_type： 杂志文章
doi：
更新日期：1985-06-01 00:00:00
abstract：:The expression of Fc mu receptors was investigated using spleen cells from (LOU/M/Wsl X CFY) F1 rats bearing the IR202 tumour, an IgM-producing immunocytoma. It was found that the progressively growing solid tumour was accompanied by an extraordinary expansion of host splenocytes with Fc mu receptors. These cells were...
journal_title：Immunology
pub_type： 杂志文章
doi：
更新日期：1987-07-01 00:00:00
abstract：:Eosinophil function is regulated by several cytokines, including interleukin-3 (IL-3), IL-5 and granulocyte-macrophage colony-stimulating factor (GM-CSF). Culture of human eosinophils with IL-3 produced a marked, dose-dependent up-regulation of CR3 expression. This was maximal after 1 day in culture and dependent on p...
journal_title：Immunology
pub_type： 杂志文章
doi：
更新日期：1992-12-01 00:00:00
abstract：:This study has examined the stimuli required for secretion of regulated upon activation, normal T-cell expressed, presumed secreted (RANTES) from T lymphocytes and found that stimuli such as phorbol 12-myristate 13-acetate (PMA), which are unable to support T-cell proliferation and interleukin-2 (IL-2) production, are...
journal_title：Immunology
pub_type： 杂志文章
doi：10.1046/j.1365-2567.2000.00072.x
更新日期：2000-09-01 00:00:00
abstract：:Growth of Salmonella enterica in mammalian tissues results from continuous spread of bacteria to new host cells. Our previous work indicated that infective S. enterica are liberated from host cells via stochastic necrotic burst independently of intracellular bacterial numbers. Here we report that liver phagocytes can ...
journal_title：Immunology
pub_type： 杂志文章
doi：10.1111/j.1365-2567.2008.02814.x
更新日期：2008-09-01 00:00:00
