Abstract：
:The awareness is increasing that in the colon many metabolic processes take place in relation to the fermentation of our food, which might be relevant for health and disease. However, the relation between food, colon metabolism and health or disease is far from clear. In this overview, the physiology of colonic metabolism and possibilities for its modification by the use of pre- and probiotics are discussed. Results of in vitro and animal studies indicate a beneficial impact of probiotics on adverse metabolic processes in the colon, but confirmation in human studies has to be extended. The administration of prebiotics seems to be promising with regard to their capacity to modulate the bacterial composition in the colon and there are indications that prebiotics can beneficially influence colonic metabolism. Whether these modulations brought about by pre- or probiotics have an effect on the health of the host, however, needs to be established in most cases.
journal_name
Eur J Nutrjournal_title
European journal of nutritionauthors
Priebe MG,Vonk RJ,Sun X,He T,Harmsen HJ,Welling GWdoi
10.1007/s00394-002-1101-8keywords:
subject
Has Abstractpub_date
2002-11-01 00:00:00pages
I2-10eissn
1436-6207issn
1436-6215journal_volume
41 Suppl 1pub_type
杂志文章,评审abstract：PURPOSE:Protein-restricted diet during pregnancy is related to oxidative stress and, as a consequence, damage to nephrogenesis. We investigated the effects of vinifera grape skin extract (ACH09)-derived polyphenols on preserving renal morphology of maternal protein-restricted 1-day-old offspring. METHODS:Female C57/Bl...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-015-0963-5
更新日期：2016-06-01 00:00:00
abstract：PURPOSE:The aim of this study was to determine whether grape polyphenols have a "second-meal effect", modulating glucose and lipid elevations in the postprandial period after two successive meals in subjects with obesity. METHODS:A randomized, double-blind, placebo-controlled, acute clinical trial was conducted. Twent...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-020-02451-6
更新日期：2021-01-02 00:00:00
abstract：BACKGROUND:At the present time the recommended daily intake or allowance (RDA) and the safe upper level (UL) of intake of micronutrients are given as single values. The recommended daily intake is considered to cover the requirements of 97.5% of the population while the safe upper level is a value for the whole populat...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-007-0691-6
更新日期：2008-02-01 00:00:00
abstract：PURPOSE:Concentration of carotenoids in the serum is a biomarker of mainly vegetable and fruit consumption. However, the levels of carotenoids in humans may decline with age and can also depend on body fat, alcohol consumption, and cigarette smoking. METHOD:Food intake and characteristics of 159 randomly chosen women ...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-013-0493-y
更新日期：2013-12-01 00:00:00
abstract：BACKGROUND:Adherence to Mediterranean diet has been shown to be associated with a better health and greater survival. The aim of the present study was to identify change-points in the relationship between food groups composing Mediterranean diet and overall mortality. METHODS:The population of the Greek EPIC prospecti...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-011-0202-7
更新日期：2012-03-01 00:00:00
abstract：PURPOSE:Diarrhea-predominant irritable bowel syndrome (IBS-D) is a common functional gastrointestinal disorder. Probiotics and synbiotics have been shown to improve symptoms of IBS, although mechanisms of action are currently not understood. METHODS:We investigated the effects of a 4-week oral synbiotic treatment (OMN...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-018-1826-7
更新日期：2019-10-01 00:00:00
abstract：PURPOSE:Tryptophan is an essential amino acid, precursor of serotonin. Serotonin (5HT) regulates the secretion of pituitary growth hormone (GH), which in turn stimulates the liver to produce insulin-like growth factor-I (IGF-I) that is necessary for development and growth. The aim of our study was to investigate the ef...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-013-0528-4
更新日期：2014-02-01 00:00:00
abstract：PURPOSE:Iron is an essential micronutrient that participates in a number of vital reactions and its absorption may be altered by various nutritional factors such as other micronutrients. Our hypothesis is that iron absorption is decreased because of the interactions with zinc and calcium. We evaluated the interaction b...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-017-1535-7
更新日期：2018-12-01 00:00:00
abstract：PURPOSES:Hepatic lipid overloading induces lipotoxicity which can cause hepatocyte damage, fibrosis, and eventually progress to cirrhosis, which is associated with nonalcoholic fatty liver disease. Adiponectin receptors play important roles in regulating lipid metabolism. In this study, we used a lentivirus system to o...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-013-0594-7
更新日期：2014-04-01 00:00:00
abstract：PURPOSE:Walnuts (Juglans regia) are known to have anti-cancer and immunomodulatory effects. However, little information is available on the effects of walnut phenolic extract (WPE) on intestinal inflammation and colitis-associated colon cancer. METHODS:COLO205 cells were pretreated with WPE and then stimulated with tu...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-018-1704-3
更新日期：2019-06-01 00:00:00
abstract：PURPOSE:Considerable variation in 25-hydroxyvitamin D (25(OH)D) in populations worldwide that seems to be independent of latitude has been reported. Therefore, we aimed to assess vitamin D status of a mid-aged German general population and to identify its dietary, lifestyle, anthropometric, and genetic determinants. M...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-013-0577-8
更新日期：2014-04-01 00:00:00
abstract：PURPOSE:The enzymes encoded by fatty acid desaturases (FADS) genes determine the desaturation of long-chain polyunsaturated fatty acids (LCPUFA). We investigated if haplotype and single nucleotide polymorphisms (SNPs) in FADS gene cluster can influence LCPUFA status in infants who received either fish oil or placebo su...
journal_title：European journal of nutrition
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00394-017-1529-5
更新日期：2018-10-01 00:00:00
abstract：PURPOSE:This study was aimed to determine the impact of hydroxytyrosol (HT), a minor compound found in olive oil, on breast cancer stem cells (BCSCs) and the migration capacity of triple-negative breast cancer (TNBC) cell lines through the alteration of epithelial-to-mesenchymal transition (EMT) and embryonic signaling...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-018-1864-1
更新日期：2019-12-01 00:00:00
abstract：PURPOSE:To investigate the longitudinal association between the macronutrient composition of the diet and frailty. METHODS:Data were obtained from 5205 Dutch middle-aged and older adults participating in the Rotterdam Study. Frailty was measured using a frailty index based on the accumulation of 38 health-related defi...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-019-02131-0
更新日期：2020-10-01 00:00:00
abstract：PURPOSE:Risks of dehydration and cognitive decline increase with advancing age, yet the relation between dehydration, water intake, and cognitive performance among older adults remains understudied. METHODS:Using data from the 2011-2014 cycles of the Nutrition and Health Examination Survey (NHANES), we tested if calcu...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-019-02152-9
更新日期：2020-10-01 00:00:00
abstract：BACKGROUND:Extensive exercise may promote the formation of reactive oxygen species and subsequently contribute to tissue damage. A compound which can protect cells and tissues is vitamin E. The vitamin E radical, formed during the radical scavenging process, can be reduced by vitamin C resulting in a higher level of th...
journal_title：European journal of nutrition
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/s00394-003-0414-6
更新日期：2003-08-01 00:00:00
abstract：PURPOSE:To investigate whether age influences colonic polyphenol metabolism. METHODS:Healthy participants, younger (n = 8; 23-43 years) and older (n = 13; 51-76 years), followed a 3-day low-polyphenol diet (LPD) and a 3-day high-polyphenol diet (HPD). Urinary phenolic acids (PA), short chain fatty acids (SCFA), pH and...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-018-1625-1
更新日期：2019-04-01 00:00:00
abstract：INTRODUCTION:Phenolic acids are important phenolic compounds widespread in foods, contributing to nutritional and organoleptic properties. FACTORS AFFCETING INDIVIDUAL VARIABILITY:The bioavailability of these compounds depends on their free or conjugated presence in food matrices, which is also affected by food proces...
journal_title：European journal of nutrition
pub_type： 杂志文章,评审
doi：10.1007/s00394-019-01987-6
更新日期：2020-06-01 00:00:00
abstract：BACKGROUND:Carotenoids in serum vary between countries and within populations with evidence suggesting a qualitative relationship to diet. Breast milk carotenoids furnish a source of vitamin A and potentially provide immunoprotection and other health benefits for infants. There have been numerous studies of milk carote...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-003-0403-9
更新日期：2003-06-01 00:00:00
abstract：PURPOSE:In this study, we sought to find the effects and mechanisms of probiotic Lactobacillus casei Zhang (L. casei Zhang) on the pro-inflammatory cytokine production and hepatic inflammatory response in a rat model of acute liver failure induced by lipopolysaccharide (LPS) and d-galactosamine (GalN). METHODS:Male Wi...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-015-0904-3
更新日期：2016-03-01 00:00:00
abstract：PURPOSE:Rebalancing the contribution of animal- and plant-based foods is needed to achieve sustainable diet. However, little is known concerning individual characteristics that may influence intake of plant-based foods and their changes over time. We aimed to assess changes in the contribution of plant-based foods to d...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-018-1752-8
更新日期：2019-08-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:Individuals with type 1 diabetes have a high risk of developing cardiovascular diseases, and it has been reported that they consume a high atherogenic diet. We examined how nutrient intake and adherence to current European nutritional recommendations evolved in a large cohort of European individua...
journal_title：European journal of nutrition
pub_type： 杂志文章,多中心研究
doi：10.1007/s00394-012-0473-7
更新日期：2013-10-01 00:00:00
abstract：PURPOSE:Ageing is associated with loss of cognitive function and an increased risk of dementia which is expected to place growing demands on health and long-term care providers. Among multiple causative factors, evidence suggests that cognitive impairment in older subjects may be influenced by diet. The objective of th...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-014-0737-5
更新日期：2015-06-01 00:00:00
abstract：PURPOSE:These days, obesity threatens the health for which one of the main interventions is calorie restriction (CR). Due to the difficulty of compliance with this treatment, CR mimetics such as resveratrol (RSV) have been considered. The present study compared the effects of RSV and CR on hypothalamic remodeling in a ...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-018-1715-0
更新日期：2019-06-01 00:00:00
abstract：BACKGROUND:Bioavailability studies with lycopene have focused on natural sources. A synthetic source has recently become available. AIM OF THE STUDY:To determine the relative bioavailabilities of synthetic and tomato-based lycopene in free living volunteers in a single-blind, randomized, placebo-controlled, parallel t...
journal_title：European journal of nutrition
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/s00394-003-0421-7
更新日期：2003-10-01 00:00:00
abstract：OBJECTIVE:To examine the determinants of adiponectin levels (i) in 23 women with anorexia nervosa (mean BMI 15.0 +/- 1.2) and 43 healthy normal weight females (mean BMI 22.3 +/- 2.3; cross-sectional design) as well as (ii) after six and twelve weeks of weight gain in subgroups of 18 and 11 anorectic patients (mean weig...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-005-0533-3
更新日期：2005-09-01 00:00:00
abstract：PURPOSE:To compare the glycaemic response of whole grain oat kernels and pearled oats cooked under normal pressure or higher pressure and examine whether replacing half of the rice in a given meal with either of the two oat grains could make a difference in acute glycaemic responses. METHODS:In a randomised crossover ...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-019-02083-5
更新日期：2020-09-01 00:00:00
abstract：PURPOSE:It was hypothesised that blackcurrant seed oil beneficially modulates metabolic disorders related to obesity and its complications. The study also aimed to investigate the potentially adverse effects of an unbalanced diet on the distal intestine. METHODS:Male Wistar rats were randomly assigned to four groups o...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-014-0775-z
更新日期：2015-09-01 00:00:00
abstract：PURPOSE:The aim was to compare the anthropometric and metabolic profiles and lifestyle behaviours of yogurt consumers and non-consumers and to determine if the observed differences persisted after adjustment for diet quality and related variables. METHODS:Using cross-sectional and follow-up data from the Québec Family...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-017-1444-9
更新日期：2018-06-01 00:00:00
abstract：PURPOSE:To estimate total sodium (Na) and potassium (K) intake using non-fasting morning urine specimens among Lebanese elementary (6-10 year old) schoolchildren. METHOD:A national cross-sectional study was conducted. A multistage cluster sampling procedure was used to select a representative sample of 1403 healthy ch...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-016-1164-6
更新日期：2017-04-01 00:00:00
