Oral treatment with vanadium of Zucker fatty rats activates muscle glycogen synthesis and insulin-stimulated protein phosphatase-1 activity.

abstract：:In this review we analyze the concepts and the experimental data on the mechanisms of the regulation of energy metabolism in muscle cells. Muscular energetics is based on the force-length relationship, which in the whole heart is expressed as a Frank-Starling law, by which the alterations of left ventricle diastolic v...

journal_title：Molecular and cellular biochemistry

authors： Saks VA,Kuznetsov AV,Vendelin M,Guerrero K,Kay L,Seppet EK

更新日期：2004-01-01 00:00:00

abstract：:Toll-like receptors (TLRs) are major receptors that mediate the innate immune and inflammatory responses, of which TLR4 has been found most closely related to human atherosclerosis. After ligands are polymerized and activated by TLR, the mitogen-activated protein kinase and nuclear factor-κB (NF-κB) pathways are activ...

journal_title：Molecular and cellular biochemistry

authors： Yang B,Zhou Z,Li X,Niu J

更新日期：2016-11-01 00:00:00

abstract：:In this study, we examined changes in the biochemical and inotropic events of the alpha(1)-adrenoceptor signaling pathway in hypothyroid rat hearts. Hypothyroidism was induced by treating experimental animals with 0.05% 6-n-propyl-2-thiouracil (PTU) in drinking water for 7 weeks. A significant decrease of beta- and an...

journal_title：Molecular and cellular biochemistry

authors： Jalali S,Durston M,Panagia V,Mesaeli N

更新日期：2006-02-01 00:00:00

abstract：:When Leishmania donovani promastigote forms, were cultured in TC-199 medium at 28 degrees C and subsequently incubated at 38 degrees C, they turned into aflagellate (amastigote-like) forms. A return of the incubation-culture temperature to 28 degrees C these amastigote-like forms to revert to promastigotes. The amasti...

journal_title：Molecular and cellular biochemistry

authors： Castilla JJ,Sanchez-Moreno M,Mesa C,Osuna A

更新日期：1995-01-26 00:00:00

abstract：:Logistic complexities of heart transplantation embossed the necessity of utilizing novel methods, which enable heart regeneration. Human cardiosphere-derived cells (hCDCs) are taken into consideration as a promising cell resource in cell therapy in recent years. In this study, we designed an electrochemical stimulatio...

journal_title：Molecular and cellular biochemistry

authors： Nazari H,Kehtari M,Rad I,Ashtari B,Joghataei MT

更新日期：2020-07-01 00:00:00

abstract：:The aim of the study was to find out whether administration of selenium (Se) will protect the immature heart against ischemia/reperfusion.The control pregnant rats were fed laboratory diet (0.237 mg Se/kg diet); experimental rats received 2 ppm Na(2)SeO(3) in the drinking water from the first day of pregnancy until da...

journal_title：Molecular and cellular biochemistry

authors： Ostadalova I,Vobecky M,Chvojkova Z,Mikova D,Hampl V,Wilhelm J,Ostadal B

更新日期：2007-06-01 00:00:00

abstract：:This study aimed to explore the potential contribution of myofibrils to contractile dysfunction in Ca2+-paradox hearts. Isolated rat hearts were perfused with Krebs-Henseleit solution (Control), followed by Ca2+-depletion, and then Ca2+-repletion after Ca2+-depletion (Ca2+-paradox) by Langendorff method. During heart ...

journal_title：Molecular and cellular biochemistry

authors： Kovács Á,Kalász J,Pásztor ET,Tóth A,Papp Z,Dhalla NS,Barta J

更新日期：2017-06-01 00:00:00

abstract：:Vascular endothelial growth factor (VEGF)-D is a crucial mediator of angiogenesis. Following myocardial infarction (MI), cardiac VEGF-D and VEGF receptor (VEGFR)-3 are significantly upregulated. In addition to endothelial cells, myofibroblasts at the site of MI highly express VEGFR-3, implicating the involvement of VE...

journal_title：Molecular and cellular biochemistry

authors： Zhao T,Zhao W,Meng W,Liu C,Chen Y,Bhattacharya SK,Sun Y

更新日期：2016-02-01 00:00:00

abstract：:Gastric pathology is a common complication in diabetes mellitus. The aim of the study was to evaluate the functions and morphological changes of the parietal cells of the rat stomach after streptozotocin-induced diabetes. Diabetes mellitus was induced in Wistar rats by a single intraperitoneal injection of streptozoto...

journal_title：Molecular and cellular biochemistry

authors： Bastaki SM,Adeghate E,Chandranath IS,Amir N,Tariq S,Hameed RS,Adem A

更新日期：2010-08-01 00:00:00

abstract：:Vaccinia virus (VV) and other pathogenic poxviruses encode for a complement control protein. The VV complement control protein or VCP, was one of the first soluble microbial proteins postulated to have an active role in the immunomodulation of the host defense. Since then, 2 other poxviruses, including variola virus a...

journal_title：Molecular and cellular biochemistry

authors： Kotwal GJ,Miller CG,Justus DE

更新日期：1998-08-01 00:00:00

abstract：:For the past 40 years, anabolic-androgenic steroids have been used by a wide variety of athletes with the hope of improving their training, endurance, and performance. The aim of this study was to examine the chronic effects of nandrolone decanoate (20 mg/kg, s.c, Deca-Durabolin DECA(®)) on oxidative stress biomarkers...

journal_title：Molecular and cellular biochemistry

authors： Nikolic T,Zivkovic V,Jevdjevic M,Djuric M,Srejovic I,Djuric D,Jeremic N,Djuric D,Bolevich S,Jakovljevic V

更新日期：2016-01-01 00:00:00

abstract：:We report the isolation of a full length cDNA from cardiac muscle that encodes a approximately 73 kDa calcium/calmodulin (CaM) dependent kinase IIbeta isoform (CaMKIIbeta(C)) that was generated by alternative splicing of the CaMKIIbeta gene. Antipeptide antibodies raised to specific regions of the kinase identified a ...

journal_title：Molecular and cellular biochemistry

authors： Singh P,Leddy JJ,Chatzis GJ,Salih M,Tuana BS

更新日期：2005-02-01 00:00:00

abstract：:The IL-6-related cytokines, LIF and cardiotrophin-1, are important growth promoting and cardioprotective agents for cardiomyocytes. However, factors that regulate their actions in the heart are poorly understood. In this study, we tested the hypothesis that endothelin-1, a peptide hormone that produces a pattern of ca...

journal_title：Molecular and cellular biochemistry

authors： Booz GW,Day JN,Speth R,Baker KM

更新日期：2002-11-01 00:00:00

abstract：:In this study, the effect of (Boc-Lys (Boc)-Arg-Asp-Ser (tBu)-OtBu), a tetrapeptide derivative (PEP1261) was examined for antiproliferative potency and apoptotic induction. Synovial fibroblasts were isolated from collagen-induced arthritic (CIA) rats and exposed to peptides viz., PEP1261, and parental peptides (KRDS a...

journal_title：Molecular and cellular biochemistry

authors： Kumar DA,Settu K,Raju KV,Kumanan K,Manohar BM,Puvanakrishnan R

更新日期：2006-01-01 00:00:00

abstract：:The pathophysiologic importance of insulin resistance in diseases such as obesity and diabetes mellitus has led to great interest in defining the mechanism of insulin action as well as the means to overcome the biochemical defects responsible for the resistance. Vanadium compounds have been discovered to mimic many of...

journal_title：Molecular and cellular biochemistry

authors： Fantus IG,Tsiani E

更新日期：1998-05-01 00:00:00

abstract：:Both NADPH oxidase (NOX) and inducible nitric oxide synthase (iNOS) are the main sources of reactive oxygen species in kidney. However, their interactions in oxidative stress and contributions to kidney fibrosis during diabetic nephropathy have not been studied. Human mesangial cells were treated with normal glucose (...

journal_title：Molecular and cellular biochemistry

authors： Gao L,Huang W,Li J

更新日期：2013-10-01 00:00:00

abstract：:In order to understand the molecular basis of cold adaptation, we have used directed evolution to transform a thermophilic lipase LipR1 into its psychrophilic counterpart. A single round of random mutagenesis followed by screening for improved variants yielded a mutant with single-point mutation LipR1M1 (S130T), with ...

journal_title：Molecular and cellular biochemistry

authors： Sharma M,Kumar R,Singh R,Kaur J

更新日期：2017-06-01 00:00:00

abstract：:Insulin receptor binding was examined in the microvillous membranes of mid-term (20-22 weeks of gestation, MT) and full-term (FT) placentas from patients with gestational diabetes mellitus (GDM) and in normal pregnant control (N). Mid-term placentas were obtained from patients who have had spontaneous abortion. The ma...

journal_title：Molecular and cellular biochemistry

authors： al-Attas OS

更新日期：1995-10-04 00:00:00

abstract：:The present investigation was carried out to evaluate the antioxidant nature of ethanolic extract of Terminalia arjuna bark (EETA) on N-nitrosodiethylamine (DEN) induced liver cancer in male Wistar albino rats. Liver cancer was induced by single intraperitonial injection of DEN (200 mg/kg). After 2 weeks of DEN admini...

journal_title：Molecular and cellular biochemistry

authors： Sivalokanathan S,Ilayaraja M,Balasubramanian MP

更新日期：2006-01-01 00:00:00

abstract：:The effect of anti-regucalcin monoclonal antibody on neutral phoshatase activity in rat liver cytosol was investigated. Phosphotyrosine, phosphoserine, and phosphothreonine were used as the substrate toward phosphatase assay. Liver cytosolic phosphatase activity with three phosphoaminoacids was significantly increased...

journal_title：Molecular and cellular biochemistry

authors： Omura M,Yamaguchi M

更新日期：1999-07-01 00:00:00

abstract：:Fat cells were preincubated for 2 h in the presence and absence of growth hormone (GH) and Dexamethasone (Dex) before the addition of increasing concentrations of either epinephrine, theophylline or glucagon and final incubation of the cells for an additional 5 minutes. GH and Dex increased by 85%, 28% and 72%, respec...

journal_title：Molecular and cellular biochemistry

authors： Harris R,Bennun A

更新日期：1976-12-10 00:00:00

abstract：:Abnormal angiogenesis underlies many pathological conditions and is critical for the growth and maintenance of various types of tumors, including hormone-dependent cancers. Since estrogens are potent carcinogens in humans and rodents, and are involved in regulating angiogenesis, this study was designed to examine the ...

journal_title：Molecular and cellular biochemistry

authors： Banerjee SK,Campbell DR,Weston AP,Banerjee DK

更新日期：1997-12-01 00:00:00

abstract：:Fatty acid-binding proteins (FABP) are abundant cytosolic proteins whose levels is responsive to nutritional, endocrine, and a variety of pathological states. Although FABPs have been investigated in vitro for several decades, little is known of their physiological function. Liver L-FABP binds both fatty acids and cho...

journal_title：Molecular and cellular biochemistry

authors： Schroeder F,Jefferson JR,Powell D,Incerpi S,Woodford JK,Colles SM,Myers-Payne S,Emge T,Hubbell T,Moncecchi D

更新日期：1993-06-09 00:00:00

abstract：:The effects of the microtubular inhibitor, podophyllotoxin, on mitochondrial respiration were determined using isolated, digitonin-permeabilized hepatocytes and isolated mitochondria. In hepatocytes, podophyllotoxin (1.5 mM) inhibited coupled and uncoupled respiration of both FAD and NAD-linked substrates. In mitochon...

journal_title：Molecular and cellular biochemistry

authors： Horrum MA,Jennett RB,Ecklund RE,Tobin RB

更新日期：1986-06-01 00:00:00

abstract：:Catalase plays a major role in the protection of tissues from toxic effects of H2O2 and partially reduced oxygen species. In the present study catalase was extracted and purified 330-fold from goat lung by acetone fractionation and successive chromatographies on DEAE-cellulose, Sephadex G-200, Blue Sepharose CL-6B and...

journal_title：Molecular and cellular biochemistry

authors： Chatterjee U,Sanwal GG

更新日期：1993-09-22 00:00:00

abstract：:Nucleocytoplasmic transport of transcription factors is essential in eukaryotes. We previously reported the presence of two functional NLSs in the homeodomain protein, aristaless-related homeobox (Arx) protein, which is a key transcriptional repressor of LMO1, SHOX2, and PAX4 during development. NLS2, that overlaps th...

journal_title：Molecular and cellular biochemistry

authors： Ye W,Lin W,Tartakoff AM,Ma Q,Tao T

更新日期：2013-09-01 00:00:00

abstract：:Cancer stem cells (CSCs) are believed to be responsible for tumor metastasis, recurrence, and high mortality of cancer patients due to their high tumorigenicity resistance to chemo-radiotherapy. Morusin possesses anti-cancer activity through attenuation of NF-κB activity, which is up-regulated in cancer stem cells. Th...

journal_title：Molecular and cellular biochemistry

authors： Wang L,Guo H,Yang L,Dong L,Lin C,Zhang J,Lin P,Wang X

更新日期：2013-07-01 00:00:00

abstract：:Cultured human umbilical vein endothelial cells (HUVECs) are a widely used model to study the regulation of endothelial production of vasoactive substances such as endothelin-1 (ET-1) and prostacyclin (PGI2) in human. As even short term culturing is known to affect the function of many cell types, we studied whether t...

journal_title：Molecular and cellular biochemistry

authors： Ranta V,Orpana A,Mikkola T,Ylikorkala O,Viinikka L

更新日期：1997-12-01 00:00:00

abstract：:The aim of the current study was to comparatively investigate the effect of inhibition of nitric oxide (NO) production by N-nitro-L-arginine methyl ester (L-NAME), an isoform non-specific inhibitor of nitric oxide synthase (NOS), after oral mucosal incision on wound tissue NO levels. A standard incision was applied to...

journal_title：Molecular and cellular biochemistry

authors： Coşkun S,Karataş F,Acartürk F,Olmuş H,Selvi M,Erbaş D

更新日期：2005-10-01 00:00:00

abstract：:Both idiopathic restrictive cardiomyopathy (IRCM) and hypertrophic cardiomyopathy (HCM) are part of the same disease spectrum and are due to sarcomeric gene mutations. A patient with restrictive physiology without left ventricular hypertrophy (LVH) would be diagnosed as IRCM, while one with LVH would be diagnosed as H...

journal_title：Molecular and cellular biochemistry

authors： Rai TS,Ahmad S,Ahluwalia TS,Ahuja M,Bahl A,Saikia UN,Singh B,Talwar KK,Khullar M

更新日期：2009-11-01 00:00:00