Reactive cutaneous cytophagocytosis in nocardiosis.

Abstract:

:Cutaneous nocardiosis, which usually manifests in the form of pustules, abscesses, or subcutaneous nodules, is occasionally found in immunocompromised patients. A 59-yr-old Korean man with myasthenia gravis and thymoma developed nodular skin lesions on his trunk. Histopathologically, abscess formation with a dense infiltrate of neutrophils and many cytophagic histiocytes were observed. Numerous filamentous organisms, which turned out to be Nocardia asteroides by culture, were also found. After sulfamethoxazole-trimethoprim therapy, all of the skin lesions rapidly decreased in size, with a marked diminution of the number of cytophagic histiocytes, and cleared up within four months. On reporting a case of cutaneous nocardiosis showing unusual histopathologic findings, we considered that reactive conditions should be included in the differential diagnosis of the cutaneous cytophagocytosis, and that nocardiosis could be one of the diseases showing reactive cytophagocytosis.

journal_name

J Korean Med Sci

authors

Kim CY,Kim TH,Lee WS,Lee AY

doi

10.3346/jkms.2002.17.2.279

keywords:

subject

Has Abstract

pub_date

2002-04-01 00:00:00

pages

279-82

issue

2

eissn

1011-8934

issn

1598-6357

pii

200204279

journal_volume

17

pub_type

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