Molecular analysis of prion protein gene (PRNP) in Korean patients with Creutzfeldt-Jakob disease.

abstract：:Histiocytic sarcoma (HS) is a very rare neoplasm that often shows an aggressive clinical course and systemic symptoms, such as fever, weight loss, adenopathy, hepatosplenomegaly and pancytopenia. It may present as localized or disseminated disease. We describe here a 63-yr-old male who manifested systemic symptoms, in...

journal_title：Journal of Korean medical science

authors： Sohn BS,Kim T,Kim JE,Bae E,Park CJ,Huh J,Lee SO

更新日期：2010-02-01 00:00:00

abstract：:One important mechanism of drug resistance in acute leukemia is the overexpression of the multi-drug resistance (MDR1) gene that encodes a 170-kDa membrane protein called P-glycoprotein. To estimate the incidence and role of MDR1 gene expression in patients with acute leukemia, we investigated the expression of MDR1 b...

journal_title：Journal of Korean medical science

authors： Jiang EZ,Chang YJ,Lee JW,Lee WK,Kim JS,Sohn SK,Lee KB,Suh JS

更新日期：1998-12-01 00:00:00

abstract：:Bone scan (BS) and serum alkaline phosphatase (ALP) concentration are used to detect bone metastasis in malignancy, although whole-body fluoro-D-glucose positron emission tomography computed tomography (FDG PET/CT) is being used increasingly. But BS is still used for the detection of metastatic bone lesion. So we comp...

journal_title：Journal of Korean medical science

authors： Min JW,Um SW,Yim JJ,Yoo CG,Han SK,Shim YS,Kim YW

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:The purpose was to compare the efficacy between tenofovir disoproxil fumarate (TDF) and lamivudine (LMV) in children with nucleos(t)ide-naive chronic hepatitis B (CHB) infection. Patients with CHB were treated with TDF in the immune-reactive phase and compared with a historical control group of patients trea...

journal_title：Journal of Korean medical science

authors： Choe JY,Ko JS,Choe BH,Kim JE,Kang B,Lee KJ,Yang HR

更新日期：2018-01-08 00:00:00

abstract：:Dominant inflammatory cytokines might be different depending on the underlying causes of acute lung injury (ALI). The role of kertinocyte-derived chemokine (KC), a potent chemoattractant for neutrophils, has not been clearly established in hemorrhage-induced ALI. In this study, lung injury and cytokine expression were...

journal_title：Journal of Korean medical science

authors： Lee BH,Lee TJ,Jung JW,Oh DJ,Choi JC,Shin JW,Park IW,Choi BW,Kim JY

更新日期：2009-10-01 00:00:00

abstract：:Intravascular papillary endothelial hyperplasia (Masson's hemangioma) is a disease characterized by exuberant endothelial proliferation within the lumen of medium-sized veins. In 1923, Masson regarded this disease as a neoplasm inducing endothelial proliferation, however, now it is considered to be a reactive vascular...

journal_title：Journal of Korean medical science

authors： Hong SG,Cho HM,Chin HM,Park IY,Yoo JY,Hwang SS,Kim JG,Park WB,Chun CS

更新日期：2004-04-01 00:00:00

abstract：:1) A beta agonist stimulated Na+ transport and decreased the intracellular Cl concentration ([Cl]c) associated with cell shrinkage via an increase in cytosolic cAMP level by activating adenylate cyclase in rat fetal distal lung epithelial (FDLE) cells. 2) Lowering [Cl-]c activated a 28-pS nonselective cation (NSC) cha...

journal_title：Journal of Korean medical science

authors： Marunaka Y,Niisato N,Ito Y

更新日期：2000-08-01 00:00:00

abstract：:Scleroderma (SSc) renal crisis has been reported to be associated with anti-RNA polymerase I and III (RNAP I/III) antibodies in Caucasians and the Japanese. However, no report is available for Korean SSc patients. Here, we describe the case of a 65-yr-old female SSc patient who developed renal crisis and whose serum c...

journal_title：Journal of Korean medical science

authors： Kang EH,Im CH,Kim SH,Chung JR,Lee EY,Kim DJ,Lee EB,Song YW

更新日期：2006-12-01 00:00:00

abstract：:With the ongoing novel coronavirus disease 2019 (COVID-19) pandemic, the number of individuals that need to be tested for COVID-19 has been rapidly increasing. A walk-through (WT) screening center using negative pressure booths that is inspired by the biosafety cabinet has been designed and implemented in Korea for ea...

journal_title：Journal of Korean medical science

authors： Kim SI,Lee JY

更新日期：2020-04-20 00:00:00

abstract：:The pneumonia severity index (PSI) and CURB-65 are widely used tools for the prediction of community-acquired pneumonia (CAP). This study was conducted to evaluate validation of severity scoring system including the PSI and CURB-65 scores of Korean CAP patients. In the prospective CAP cohort (participated in by 14 hos...

journal_title：Journal of Korean medical science

authors： Kim HI,Kim SW,Chang HH,Cha SI,Lee JH,Ki HK,Cheong HS,Yoo KH,Ryu SY,Kwon KT,Lee BK,Choo EJ,Kim DJ,Kang CI,Chung DR,Peck KR,Song JH,Suh GY,Shim TS,Kim YK,Kim HY,Moon CS,Lee HK,Park SY,Oh JY,Jung SI,Park

更新日期：2013-09-01 00:00:00

abstract：:The purpose of this study was to explore the role of epithelial-mesenchymal transition in the pathogenesis of hepatolithiasis. Thirty-one patients with primary hepatolithiasis were enrolled in this study. Expressions of E-cadherin, alpha-catenin, alpha-SMA, vimentin, S100A4, TGF-beta1 and P-smad2/3 in hepatolithiasis ...

journal_title：Journal of Korean medical science

authors： Zhao L,Yang R,Cheng L,Wang M,Jiang Y,Wang S

更新日期：2010-07-01 00:00:00

abstract：:We investigated the incidence of unsuspected gallbladder (GB) carcinomas in a total of 527 consecutive GB specimens resected for benign biliary disease and their clinicopathological features. The GBs were examined microscopically using stepwise tissue sections at 5 mm interval. Clinical and pathological findings were ...

journal_title：Journal of Korean medical science

authors： Kwon SY,Chang HJ

更新日期：1997-12-01 00:00:00

abstract：BACKGROUND:There is a controversy about the effect of having a usual source of care on medical expenses. Although many studies have shown lower medical expenses in a group with a usual source of care, some have shown higher medical expenses in such a group. This study aimed to empirically demonstrate the effect of havi...

journal_title：Journal of Korean medical science

authors： Kim D,Kim S,Park HK,Ha IH,Jung B,Ryu WH,Lee SI,Sung NJ

更新日期：2019-09-09 00:00:00

abstract：:Interleukin (IL)-33 is an important mediator of innate immunity. Behcet's disease (BD) is an autoinflammatory disorder characterized by hyperactivity of the innate immune response. We measured serum levels of IL-33 and its receptor soluble ST2 (sST2) in patients with BD to investigate their association with disease ac...

journal_title：Journal of Korean medical science

authors： Kim DJ,Baek SY,Park MK,Park KS,Lee JH,Park SH,Kim HY,Kwok SK

更新日期：2013-08-01 00:00:00

abstract：:This prospective study aimed to evaluate the satisfaction of patients who participated in the decision-making process for selecting an anesthesia method for surgery; the patients' preferred role (active, collaborative or passive) in the decision-making; and the patients' preferred choice of anesthetic method. The stud...

journal_title：Journal of Korean medical science

authors： Hwang SM,Lee JJ,Jang JS,Gim GH,Kim MC,Lim SY

更新日期：2014-02-01 00:00:00

abstract：:This observational study aimed at evaluating recent superwarfarin intoxication of Korean patients. Ten patients were diagnosed as or highly suspicious for superwarfarin intoxication. Case report forms described by attending hematologists of the patients were collected and analyzed. Bleeding symptoms were varied among ...

journal_title：Journal of Korean medical science

authors： Hong J,Yhim HY,Bang SM,Bae SH,Yuh YJ,Yoon SS,Yoon HJ,Kim ST,Chi HS

更新日期：2010-12-01 00:00:00

abstract：:Carcinosarcoma of the adrenal gland is an extremely rare variant of adrenocortical carcinoma, characterized by a biphasic pattern of carcinoma and sarcoma-like components. We report a case of adrenal carcinosarcoma occurring in a 61-year-old Korean man who presented with right flank pain of one month duration radiatin...

journal_title：Journal of Korean medical science

authors： Lee MS,Park IA,Chi JG,Ham EK,Lee KC,Lee CW

更新日期：1997-08-01 00:00:00

abstract：:NAD(P)H oxidase plays an important role in hypertension and its complication in aldosterone-salt rat. We questioned whether NAD(P)H oxidase subunit expression and activity are modulated by aldosterone and whether this is associated with target-organ damage. Rats were infused with aldosterone (0.75 microg/hr/day) for 6...

journal_title：Journal of Korean medical science

authors： Park YM,Lim BH,Touyz RM,Park JB

更新日期：2008-12-01 00:00:00

abstract：:Recent evidence suggests that gastric mucosal injury induces adaptive changes in DNA methylation. In this study, the methylation status of the key tissue-specific genes in normal gastric mucosa of healthy individuals and cancer patients was evaluated. The methylation-variable sites of 14 genes, including ulcer-healing...

journal_title：Journal of Korean medical science

authors： Hong SJ,Oh JH,Jung YC,Kim YH,Kim SJ,Kang SJ,Seo EJ,Choi SW,Kang MI,Rhyu MG

更新日期：2010-03-01 00:00:00

abstract：:Heart rate (HR) change during sleepy driving has never been investigated. Healthy volunteers who planned to drive a long distance were recruited and monitored with a 24-hour Holter. Six healthy volunteers were enrolled. Their mean driving time was 297.7 ± 111 minutes. Mean duration of sleepy time while driving was 27 ...

journal_title：Journal of Korean medical science

authors： Jo SH,Kim JM,Kim DK

更新日期：2019-02-12 00:00:00

abstract：:Phospholipase C (PLC) and related enzymes in signal transduction system are closely linked to cellular damage in ischemic encephalopathy. This study was undertaken to elucidate the time sequential changes of PLC isoenzymes (beta and gamma) in vulnerable areas of hippocampus in global ischemia and infarcted area in foc...

journal_title：Journal of Korean medical science

authors： Koo H

更新日期：1996-02-01 00:00:00

abstract：:[This corrects the article e66 in vol. 34, PMID: 30833883.]. ...

journal_title：Journal of Korean medical science

authors：

更新日期：2019-03-06 00:00:00

abstract：:We aimed to investigate the clinical value of persistent but downgraded vesicoureteral reflux (VUR) after dextranomer/hyaluronic acid (Dx/HA) injection in children. The medical records of 128 children (195 ureters) who underwent Dx/HA injections for VUR were reviewed. The incidences of pre- and post-operative febrile ...

journal_title：Journal of Korean medical science

authors： Baek M,Kang MY,Lee HE,Park K,Choi H

更新日期：2013-07-01 00:00:00

abstract：:This study examined the add-on efficacy of eye movement desensitization and reprocessing (EMDR) therapy among adult civilians with post-traumatic stress disorder (PTSD) who continued to be symptomatic after more than 12 weeks of initial antidepressant treatment. Scores for the Clinician Administered PTSD Scale (CAPS) ...

journal_title：Journal of Korean medical science

authors： Bae H,Kim D,Cho Y,Kim D,Kim SH

更新日期：2018-11-05 00:00:00

abstract：:The authors report a typical case of tenosynovial giant cell tumor of the right middle finger of a 31-year-old man. Histologically, this tumor is characterized by a discrete proliferation of rounded synovial-like cells accompanied by a variable number of multinucleated giant cells, inflammatory cells, and xanthoma cel...

journal_title：Journal of Korean medical science

authors： Hwang K,Lee DK,Lee SI

更新日期：1999-12-01 00:00:00

abstract：:Since the cancer has been the leading cause of deaths in Korea, estimation of the cancer deaths for the upcoming years in the population using the vital statistics is considered to be necessary. The aim of this study was to estimate the number and trends of cancer deaths in Korea. The expected numbers of cancer deaths...

journal_title：Journal of Korean medical science

authors： Bae JM,Jung KW,Won YJ

更新日期：2002-10-01 00:00:00

abstract：:Seasonal influenza is a significant cause of morbidity and mortality of children in Korea. However, few data are available on parental perception and action toward childhood influenza. This study aimed to characterize parental perception and patterns of action in response to influenza and influenza-like illnesses (ILI...

journal_title：Journal of Korean medical science

authors： Hwang JH,Lim CH,Kim DH,Eun BW,Jo DS,Song YH,Kim YK

更新日期：2017-02-01 00:00:00

abstract：:Gestational diabetes mellitus (GDM) is a strong predictor of postpartum prediabetes and transition to overt type 2 diabetes (T2DM). Although many reports indicate that low magnesium is correlated with deteriorated glucose tolerance, the association between postpartum serum magnesium level and the risk for T2DM in wome...

journal_title：Journal of Korean medical science

authors： Yang SJ,Hwang SY,Baik SH,Lee KW,Nam MS,Park YS,Woo JT,Kim YS,Park S,Park SY,Yim CH,Yoon HK,Kim SH

更新日期：2014-01-01 00:00:00

abstract：:Hallervorden-Spatz syndrome (HSS) is a heredodegenerative disorder characterized by both progressive pyramidal and extrapyramidal signs, dysarthric speech, and mental deterioration. No diagnostic biochemical test is yet available, and diagnosis of HSS can be confirmed only at autopsy by the characteristic neuropatholo...

journal_title：Journal of Korean medical science

authors： Kim DW,Choi Y,Kim KJ,Ko TS,Hwang YS,Kim IW

更新日期：1993-10-01 00:00:00

abstract：:X-linked hypophosphatemic rickets (XLH) results from mutations in the PHEX gene. Mutational analysis of the PHEX gene in 15 unrelated Korean patients with hypophosphatemic rickets revealed eight mutations, including five novel mutations, in nine patients: two nonsense mutations, two missense mutations, one insertion, ...

journal_title：Journal of Korean medical science

authors： Song HR,Park JW,Cho DY,Yang JH,Yoon HR,Jung SC

更新日期：2007-12-01 00:00:00