Abstract:
:1) A beta agonist stimulated Na+ transport and decreased the intracellular Cl concentration ([Cl]c) associated with cell shrinkage via an increase in cytosolic cAMP level by activating adenylate cyclase in rat fetal distal lung epithelial (FDLE) cells. 2) Lowering [Cl-]c activated a 28-pS nonselective cation (NSC) channel by elongating the open time of the channel. 3) cAMP signals were converted to a protein tyrosine kinase (PTK)-mediated signal. 4) The PTK-mediated signal was involved in the cAMP-stimulated Na+ transport in rat FDLE cells.
journal_name
J Korean Med Scijournal_title
Journal of Korean medical scienceauthors
Marunaka Y,Niisato N,Ito Ydoi
10.3346/jkms.2000.15.S.S42keywords:
subject
Has Abstractpub_date
2000-08-01 00:00:00pages
S42-3eissn
1011-8934issn
1598-6357journal_volume
15 Supplpub_type
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