Abstract：
:In 2007, the Korean Interstitial Lung Disease Society had collected clinical data of patients who have diagnosed as Lymphangioleiomyomatosis (LAM) since 1990 through nationwide survey, which showed that LAM patients had increased sharply after 2004. The present study was performed to show the clinical features of Korean patients with LAM, and to establish the reason for the recent increase in the diagnosis. All 63 patients were women and the mean age at diagnosis was 36 yr. The most common presenting symptom was dyspnea and 8 patients had tuberous sclerosis complex. The survival rate at 5 yr after diagnosis was 84%. Compared with patients diagnosed after 2004 (n=34), the patients diagnosed before 2004 (n=29) complained with dyspnea more (P=0.016) and had lower FEV(1)% predicted (P=0.003), and DLco% predicted (P=0.042). The higher proportion of patients diagnosed after 2004 showed the normal chest radiography, and they were detected by routine chest CT screening (P=0.016). This study showed that clinical features of Korean patients with LAM were not different from those reported elsewhere. It is concluded that the reason for the increase of newly diagnosed patients is the result of increase in detection of the early stage LAM by the widespread use of chest CT screening.
journal_name
J Korean Med Scijournal_title
Journal of Korean medical scienceauthors
Park HY,Nam HS,Chung MP,Jeong SH,Kim YJ,Cha SI,Kim YW,Park JS,Uh ST,Park CS,Park MS,Moon JA,Jung KS,Jegal YJ,Kim DS,Song JW,Yum HK,Park YBdoi
10.3346/jkms.2010.25.8.1182subject
Has Abstractpub_date
2010-08-01 00:00:00pages
1182-6issue
8eissn
1011-8934issn
1598-6357journal_volume
25pub_type
杂志文章abstract：:Increased epithelial cell proliferation is associated with an increased risk of gastric carcinoma. Helicobacter pylori infection is an established risk factor for gastric cancer and the organism has recently been classified as a group I carcinogen by an IARC working group. In this study, we describe differences in gas...
journal_title：Journal of Korean medical science
pub_type： 杂志文章
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journal_title：Journal of Korean medical science
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doi：10.3346/jkms.1998.13.6.676
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journal_title：Journal of Korean medical science
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journal_title：Journal of Korean medical science
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journal_title：Journal of Korean medical science
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pub_type： 杂志文章
doi：10.3346/jkms.2007.22.4.682
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journal_title：Journal of Korean medical science
pub_type： 杂志文章
doi：10.3346/jkms.2004.19.1.101
更新日期：2004-02-01 00:00:00
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journal_title：Journal of Korean medical science
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doi：10.3346/jkms.2018.33.e179
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journal_title：Journal of Korean medical science
pub_type： 杂志文章
doi：10.3346/jkms.1993.8.1.34
更新日期：1993-02-01 00:00:00
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journal_title：Journal of Korean medical science
pub_type： 杂志文章
doi：10.3346/jkms.2010.25.2.257
更新日期：2010-02-01 00:00:00
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journal_title：Journal of Korean medical science
pub_type： 杂志文章
doi：10.3346/jkms.2011.26.3.457
更新日期：2011-03-01 00:00:00
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journal_title：Journal of Korean medical science
pub_type： 杂志文章,评审
doi：10.3346/jkms.2015.30.5.514
更新日期：2015-05-01 00:00:00
abstract：:Recent evidence suggests that gastric mucosal injury induces adaptive changes in DNA methylation. In this study, the methylation status of the key tissue-specific genes in normal gastric mucosa of healthy individuals and cancer patients was evaluated. The methylation-variable sites of 14 genes, including ulcer-healing...
journal_title：Journal of Korean medical science
pub_type： 杂志文章
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pub_type： 杂志文章
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journal_title：Journal of Korean medical science
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journal_title：Journal of Korean medical science
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journal_title：Journal of Korean medical science
pub_type： 杂志文章
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abstract：:To establish the early morphogenetic mechanism in retinoid induced cardiac lesions, we investigated the morphology of the heart in cultured rat embryos treated with retinoic acid (RA) at 9.0 and 9.5 days post coitum (d.p.c). Wistar rat embryos were treated with RA (2 x 10(-7) M) for 6 hours from the embryonic day equi...
journal_title：Journal of Korean medical science
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doi：10.3346/jkms.1998.13.2.117
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abstract：:Previous epidemiologic studies have shown the clinical association between non-alcoholic fatty liver disease (NAFLD) and cardiovascular disease (CVD). However, there is only limited information about the effect of NAFLD on the development of hypertension. Accordingly, we investigated the clinical association between N...
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journal_title：Journal of Korean medical science
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doi：10.3346/jkms.2010.25.7.1005
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abstract：:The localization and functional characteristics of tumor necrosis factor(TNF) beta gene raise the possibility that it may be involved in the susceptibility to autoimmune thyroid diseases. To investigate whether a TNF beta gene polymorphism is associated with autoimmune thyroiditis, we analyzed the TNF beta gene polymo...
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pub_type： 临床试验,杂志文章
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abstract：:With the ongoing novel coronavirus disease 2019 (COVID-19) pandemic, the number of individuals that need to be tested for COVID-19 has been rapidly increasing. A walk-through (WT) screening center using negative pressure booths that is inspired by the biosafety cabinet has been designed and implemented in Korea for ea...
journal_title：Journal of Korean medical science
pub_type： 杂志文章
doi：10.3346/jkms.2020.35.e154
更新日期：2020-04-20 00:00:00
abstract：BACKGROUND:Disease-specific factors that predispose patients to diverse cardiac diseases in systemic lupus erythematosus (SLE) have been established. The aim of this study was to identify risk factors for cardiac involvement in patients with SLE drawn from the Korean Lupus Network (KORNET) registry. METHODS:A total of...
journal_title：Journal of Korean medical science
pub_type： 杂志文章
doi：10.3346/jkms.2020.35.e139
更新日期：2020-06-01 00:00:00
