Reduction in Alpha Peak Frequency and Coherence on Quantitative Electroencephalography in Patients with Schizophrenia.

Abstract:

Background:The aim of the study was to examine the characteristics of alpha wave peak frequency, power, and coherence in patients with schizophrenia. Methods:Thirty-one patients with schizophrenia and age- and sex-matched subjects with no psychopathology were enrolled. All study participants underwent quantitative electroencephalography (QEEG). Alpha-related values, including peak frequency, power, and coherence, were evaluated. Results:Alpha peak frequency on the Oz area was slower in the schizophrenia group than that in the control group. However, no differences in absolute or relative power were observed between the two groups. Significant reductions in absolute and relative coherence were observed at the C3-C4 and T3-T4 nodes in the patients with schizophrenia. Relative coherence was reduced at the P3-P4 nodes. Conclusion:This study focused on alpha variables detected in QEEG as intrinsic values to distinguish schizophrenia from a healthy control. The results suggest decreased alpha peak frequency of the occipital lobe and decreased coherence between the two hemispheres in patients with schizophrenia. A further study could elucidate the causal relationship and biological meaning of the variations in alpha waves in patients with schizophrenia.

journal_name

J Korean Med Sci

authors

Yeum TS,Kang UG

doi

10.3346/jkms.2018.33.e179

subject

Has Abstract

pub_date

2018-05-17 00:00:00

pages

e179

issue

26

eissn

1011-8934

issn

1598-6357

journal_volume

33

pub_type

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