Abstract:
:This study was conducted to evaluate age-specific seroprevalence of pertussis in Korea and to formulate a strategy to prevent and reduce the incidence of pertussis. Residual serum samples of healthy adolescents and adults 11 yr of age or older were collected between July 2012 and December 2012, and anti-pertussis toxin (PT) IgG titers were measured using a commercial ELISA kit. We compared the mean anti-PT IgG titers and seroprevalence of pertussis of the six age groups: 11-20, 21-30, 31-40, 41-50, 51-60, and ≥ 61 yr. A total of 1,192 subjects were enrolled. The mean anti-PT IgG titer and pertussis seroprevalence were 35.53 ± 62.91 EU/mL and 41.4%, respectively. The mean anti-PT IgG titers and seroprevalence were not significantly different between the age groups. However, the seroprevalence in individuals 51 yr of age or older was significantly higher than in individuals younger than 51 yr (46.5% vs 39.1%, P = 0.017). Based on these results, a new pertussis prevention strategy is necessary for older adults.
journal_name
J Korean Med Scijournal_title
Journal of Korean medical scienceauthors
Lee SY,Han SB,Bae EY,Kim JH,Kang JH,Park YJ,Ma SHdoi
10.3346/jkms.2014.29.5.652subject
Has Abstractpub_date
2014-05-01 00:00:00pages
652-6issue
5eissn
1011-8934issn
1598-6357journal_volume
29pub_type
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