A case of cholestatic autoimmune hepatitis and acute liver failure: an unusual hepatic manifestation of mixed connective tissue disease and Sjögren's syndrome.

abstract：:We aimed to elucidate whether the eNOS T-786C mutant allele is implicated in subarachnoid hemorrhage (SAH) susceptibility or vasospasm after SAH, and whether the mutant allele is differentially expressed in those with small and large ruptured aneurysms in Korean population. 136 consecutive patients diagnosed with aneu...

journal_title：Journal of Korean medical science

authors： Song MK,Kim MK,Kim TS,Joo SP,Park MS,Kim BC,Cho KH

更新日期：2006-10-01 00:00:00

abstract：:We determined the relationship between the progression of immunoglobulin A nephropathy (IgAN) and the A1818T polymorphism in intron 2 of Angiotensin II type 2 receptor (AT2R) gene, which might play protective roles in the pathogenesis of IgAN. Patients with biopsy-proven IgAN were recruited from the registry of the Pr...

journal_title：Journal of Korean medical science

authors： Yoon HJ,Chin HJ,Na KY,Chae DW,Kim S,Jeon US,Chung WK,Lee HH,Yang J,Kim S,Kwon YJ,Kim HC,Park SB,Kim HY,Lee TW,Progressive REnal disease and Medical Informatics and gEnomics Research (PREMIER) members.

更新日期：2009-01-01 00:00:00

abstract：:The determination of adjustment method of urinary mercury in spot urine is one of the important issues in assessing the health risks of mercury workers. But there have been debates about whether creatinine or other forms of correction for urinary concentration are better in reducing the variation of urinary mercury. W...

journal_title：Journal of Korean medical science

authors： Lee E,Park HK,Kim HJ

更新日期：1996-08-01 00:00:00

abstract：:Since the cancer has been the leading cause of deaths in Korea, estimation of the cancer deaths for the upcoming years in the population using the vital statistics is considered to be necessary. The aim of this study was to estimate the number and trends of cancer deaths in Korea. The expected numbers of cancer deaths...

journal_title：Journal of Korean medical science

authors： Bae JM,Jung KW,Won YJ

更新日期：2002-10-01 00:00:00

abstract：:Four cases of well differentiated lymphocytic lymphoma with or without plasmacytoid differentiation of the lung are described. Two cases were single and the others were multiple. Histologic pictures of the lesion showed mass with perivascular, interstitial and alveolar extension in three cases and only interstitial an...

journal_title：Journal of Korean medical science

authors： Kim I

更新日期：1987-06-01 00:00:00

abstract：:Creutzfeldt-Jakob disease (CJD), a relatively uncommon human dementia, is caused by an unconventional slow infectious agent. Several cases of CJD, clinically or histopathologically diagnosed, have been reported in Korea. In order to confirm the diagnosis of CJD and also differential diagnosis of sporadic and familial ...

journal_title：Journal of Korean medical science

authors： Jeong BH,Ju WK,Huh K,Lee EA,Choi IS,Im JH,Choi EK,Kim YS

更新日期：1998-06-01 00:00:00

abstract：:Primary malignant melanoma of the esophagus (PMME) is an extremely rare tumor with only scattered cases reported. Although surgical resection has been considered as the best possible option, the prognosis has been nonetheless poor. We report a case of PMME which was treated by surgical resection and additionally follo...

journal_title：Journal of Korean medical science

authors： Lee SA,Hwang JJ,Choi YH

更新日期：2007-02-01 00:00:00

abstract：:Clinical research registration is required in many countries to improve transparency of clinical research and to ensure subject safety. Developed in February 2010, the Clinical Research Information Service (CRIS) is an online registration system for clinical studies in Korea and one of the primary registries of the Wo...

journal_title：Journal of Korean medical science

authors： Choi EK,Kim MJ,Lim NK,Park HY

更新日期：2016-01-01 00:00:00

abstract：:We investigated the association between socioeconomic status and hypertension in Korea, a country that has experienced a dynamic socioeconomic transition. We analyzed participants of a prospective cohort study-the Korean Genome and Epidemiology Study-enrolled between 2001 and 2003. We recruited 7,089 subjects who unde...

journal_title：Journal of Korean medical science

authors： Park CS,Ha KH,Kim HC,Park S,Ihm SH,Lee HY

更新日期：2016-12-01 00:00:00

abstract：:Sarcoidosis is a systemic granulomatous disease of unknown etiology that involves many organs, occasionally mimicking malignancy. We herein report a 50-yr-old woman of muscular sarcoidosis of chronic myopathic type, manifested by hypercalcemia and muscle wasting. Besides insignificant hilar lymphadenopathy, her sarcoi...

journal_title：Journal of Korean medical science

authors： Han EJ,Jang YS,Lee IS,Lee JM,Kang S,Kim HS

更新日期：2013-09-01 00:00:00

abstract：:Despite the prophylaxis and preemptive strategies using potent antiviral agents, cytomegalovirus (CMV) remains a major infectious cause of morbidity and mortality in allogeneic stem cell transplantation (SCT) recipients. Delayed immune reconstitution after SCT, such as cord blood and T-cell depleted SCT with the use o...

journal_title：Journal of Korean medical science

authors： Lee S,Kim SH,Choi SM,Lee DG,Kim SY,Lee JW,Min WS,Shin WS,Kim CC

更新日期：2010-04-01 00:00:00

abstract：:Hepatic fibrogenesis, a complex process that involves a marked accumulation of extracellular matrix components, activation of cells capable of producing matrix materials, cytokine release, and tissue remodeling, is regulated by matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs). The M...

journal_title：Journal of Korean medical science

authors： Park SY,Shin HW,Lee KB,Lee MJ,Jang JJ

更新日期：2010-04-01 00:00:00

abstract：:This study aimed to examine influenza vaccination coverage of North Korean defectors (NKD) in the Republic of Korea (Korea) and explore the factors affected the vaccination coverage. Total 378 NKD were analyzed. Four Korean control subjects were randomly matched by age and gender from the Korea National Health and Nut...

journal_title：Journal of Korean medical science

authors： Song IG,Lee H,Yi J,Kim MS,Park SM

更新日期：2015-09-01 00:00:00

abstract：Background:This study aimed to identify the gender-specific characteristics of the surrogate measures of insulin resistance and to establish valid cut-off values for metabolic abnormalities in a representative sample in Korea. Methods:Data were collected from the datasets of the Korean National Health and Nutrition Ex...

journal_title：Journal of Korean medical science

authors： Moon S,Park JH,Jang EJ,Park YK,Yu JM,Park JS,Ahn Y,Choi SH,Yoo HJ

更新日期：2018-06-05 00:00:00

abstract：:NAD(P)H oxidase plays an important role in hypertension and its complication in aldosterone-salt rat. We questioned whether NAD(P)H oxidase subunit expression and activity are modulated by aldosterone and whether this is associated with target-organ damage. Rats were infused with aldosterone (0.75 microg/hr/day) for 6...

journal_title：Journal of Korean medical science

authors： Park YM,Lim BH,Touyz RM,Park JB

更新日期：2008-12-01 00:00:00

abstract：:Alzheimer's disease (AD) is the most common form of dementia caused by neurodegenerative process and is tightly related to amyloid β (Aβ) and neurofibrillary tangles. The lack of early diagnostic biomarker and therapeutic remedy hinders the prevention of increasing population of AD patients every year. In spite of acc...

journal_title：Journal of Korean medical science

authors： Han SH,Mook-Jung I

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Hepatocellular carcinoma (HCC) recurrence and development of de novo malignancy (DNM) after liver transplantation (LT) are the major causes of late recipient death. METHODS:We analyzed the incidence of extrahepatic DNM following living donor LT according to the status of pretransplant hepatic malignancy. We...

journal_title：Journal of Korean medical science

authors： Park GC,Hwang S,Ahn CS,Kim KH,Moon DB,Ha TY,Song GW,Jung DH,Yoon YI,Cho HD,Kwon JH,Chung YK,Kang SH,Choi JU,Jung IJ,Lee SG

更新日期：2020-03-23 00:00:00

abstract：:Light chain deposition disease (LCDD) is a rare disorder associated with a clonal proliferation of plasma cells, which synthesize abnormal monoclonal immunoglobulin light chains. LCDD is characterized by systemic deposition of light chains in various organs, with the kidneys being most commonly affected. There have be...

journal_title：Journal of Korean medical science

authors： Kim HJ,Park E,Lee TJ,Do JH,Cha YJ,Lee SJ

更新日期：2012-02-01 00:00:00

abstract：:Myxedema coma is the extreme form of untreated hypothyroidism. In reality, few patients present comatose with severe myxedema. We describe a patient with myxedema coma which was initially misdiagnosed as a brain stem infarct. She presented to the hospital with alteration of the mental status, generalized edema, hypoth...

journal_title：Journal of Korean medical science

authors： Ahn JY,Kwon HS,Ahn HC,Sohn YD

更新日期：2010-09-01 00:00:00

abstract：:Japanese encephalitis (JE) cases have been increasingly reported recently especially in Seoul and its vicinity. Pigs are known as amplifying host of JE virus (JEV), but do not play an important role in these recent events because pig-breeding is not common in Seoul. The distribution and the density of migratory birds ...

journal_title：Journal of Korean medical science

authors： Bae W,Kim JH,Kim J,Lee J,Hwang ES

更新日期：2018-02-26 00:00:00

abstract：:Follicular variant papillary thyroid cancer (FVPTC) is the second most common subtype after conventional PTC. We compared ultrasonographic (US) features of FVPTC to those of conventional PTC according to tumor size. We reviewed US findings, pathologic reports, and medical charts of 249 PTC patients with surgically pro...

journal_title：Journal of Korean medical science

authors： Jeon EJ,Jeong YJ,Park SH,Cho CH,Shon HS,Jung ED

更新日期：2016-03-01 00:00:00

abstract：:Central obesity has been reported as a risk for atherosclerosis and metabolic syndrome. The influence of central obesity on diurnal blood pressure (BP) has not been established. In this study, we investigated the influence of central obesity on the circadian parameters of BP by 24 hr ambulatory BP monitoring. Total 1,...

journal_title：Journal of Korean medical science

authors： Kang IS,Pyun WB,Shin J,Kim JH,Kim SG,Shin GJ

更新日期：2013-10-01 00:00:00

abstract：:To investigate the function and regulation mechanism of ATP-binding cassette, subfamily G, member 2 (ABCG2) in retinoblastoma cancer stem cells (RCSCs), a long-term culture of RCSCs from WERI-Rb1 cell line was successfully established based on the high expression level of ABCG2 on the surface of RCSCs. To further expl...

journal_title：Journal of Korean medical science

authors： Jia M,Wei Z,Liu P,Zhao X

更新日期：2016-06-01 00:00:00

abstract：Background:We investigated how cataract surgery might influence long-term intraocular pressure (IOP) change in both healthy subjects and glaucoma patients. Methods:A retrospective analysis of patients who had had clear corneal phacoemulsification with a minimum of 12 months of follow up was performed. Glaucoma patient...

journal_title：Journal of Korean medical science

authors： Baek SU,Kwon S,Park IW,Suh W

更新日期：2019-01-30 00:00:00

abstract：:The aim of this study was to determine candidemia incidence among patients in a medical intensive-care unit (MICU) and the associated mortality rate and to identify risk factors associated with candidemia. We retrospectively performed a 1:3 matched case-control study of MICU patients with candidemia. Controls were mat...

journal_title：Journal of Korean medical science

authors： Han SS,Yim JJ,Yoo CG,Kim YW,Han SK,Shim YS,Lee SM

更新日期：2010-05-01 00:00:00

abstract：:An animal model of spinal cord trauma is essential for understanding the injury mechanisms, cord regeneration, and to aid the development of new therapeutic modalities. This study focused on the development of a graded experimental contusion model for spinal cord injury (SCI) using a pneumatic impact device made in Ko...

journal_title：Journal of Korean medical science

authors： Yeo SJ,Hwang SN,Park SW,Kim YB,Min BK,Kwon JT,Suk JS

更新日期：2004-08-01 00:00:00

abstract：:Telomere shortening and telomerase activation occur frequently in cases of colorectal carcinoma. In this study, we correlated the clinicopathological parameters with the telomere length in colorectal carcinomas, colonic polyps, and normal colonic tissues. We also investigated whether the telomere length changes reflec...

journal_title：Journal of Korean medical science

authors： Kim HR,Kim YJ,Kim HJ,Kim SK,Lee JH

更新日期：2002-06-01 00:00:00

abstract：:X-linked hyper-IgM syndrome (XHIM) is a rare primary immunodeficiency disorder, caused by mutations of the gene encoding CD40 ligand (CD40L; CD154). We report the clinical manifestations and mutational analysis of the CD40L gene observed in a male patient from a XHIM family. Having hypogammaglobulinemia and elevated I...

journal_title：Journal of Korean medical science

authors： Jo EK,Kim HS,Lee MY,Iseki M,Lee JH,Song CH,Park JK,Hwang TJ,Kook H

更新日期：2002-02-01 00:00:00

abstract：:A santorinicele is defined as a focal cystic dilatation of the terminal portion of the dorsal pancreatic duct at the minor papilla. Most cases reported previously were associated with pancreas divisum and a santorinicele without pancreas divisum is known to be rare. We recently experienced a typical case of a santorin...

journal_title：Journal of Korean medical science

authors： Nam KD,Joo KR,Jang JY,Kim NH,Lee SK,Dong SH,Kim HJ,Kim BH,Chang YW,Lee JI,Chang R

更新日期：2006-04-01 00:00:00

abstract：:The mechanisms of estrogen and progesterone in human cutaneous pigmentation are largely unknown. The molecular identification of estrogen receptor (ER) and progesterone receptor (PR) in the human melanocytes is of great importance to understand the mechanisms. We performed immunocytochemistry analysis and demonstrated...

journal_title：Journal of Korean medical science

authors： Im S,Lee ES,Kim W,On W,Kim J,Lee M,Kang WH

更新日期：2002-02-01 00:00:00