Diverse molecular targets for therapeutic strategies in Alzheimer's disease.

abstract：:Pulmonary bronchogenic cyst in adults is rare and the typical appearance is a sharply circumscribed, round or oval nodule or mass, usually in the medial third of the lungs. Bronchial polyps are rare histopathologically distinct nonneoplastic endobronchial lesions and are classified as multiple papillomas, solitary pap...

journal_title：Journal of Korean medical science

authors： Kim JH,Jang AS,Park JS,Lee JH,Park SW,Koh ES,Park JS,Park CS

更新日期：2005-10-01 00:00:00

abstract：:Activated protein C (APC) is known to be beneficial on ischemia reperfusion injury in myocardium. However, the protection mechanism of APC is not fully understood. The purpose of this study was to investigate the effects and possible mechanisms of APC on myocardial ischemic damage. Artificially ventilated anaesthetize...

journal_title：Journal of Korean medical science

authors： Ding JW,Tong XH,Yang J,Liu ZQ,Zhang Y,Yang J,Li S,Li L

更新日期：2010-11-01 00:00:00

abstract：:We describe a 51-yr-old man presenting with syncope due to torsade de pointes. The torsade de pointes was refractory to conventional medical therapy, including infusion of isoproterenol, MgSO4, potassium, lidocaine, and amiodarone. His past history, physical findings, and hormone study confirmed that QT prolongation w...

journal_title：Journal of Korean medical science

authors： Kim NH,Cho JG,Ahn YK,Lee SU,Kim KH,Cho JH,Kim HG,Kim W,Jeong MH,Park JC,Kang JC

更新日期：2001-06-01 00:00:00

abstract：:Despite rapid increase in incidence of prostate cancer (PC) and PC survivors, there are few studies regarding competing causes of death and time trends in Asian population. We conducted a cohort study of 2% nationwide random sample of Korean National Health Insurance employees. A total of 873 patients who had received...

journal_title：Journal of Korean medical science

authors： Park J,Suh B,Shin DW,Hong JH,Ahn H

更新日期：2016-11-01 00:00:00

abstract：:A santorinicele is defined as a focal cystic dilatation of the terminal portion of the dorsal pancreatic duct at the minor papilla. Most cases reported previously were associated with pancreas divisum and a santorinicele without pancreas divisum is known to be rare. We recently experienced a typical case of a santorin...

journal_title：Journal of Korean medical science

authors： Nam KD,Joo KR,Jang JY,Kim NH,Lee SK,Dong SH,Kim HJ,Kim BH,Chang YW,Lee JI,Chang R

更新日期：2006-04-01 00:00:00

abstract：:The rapid increases in childhood obesity and physical inactivity are linked to the incidence of diabetes among young individuals. However, few studies have evaluated the prevalence of diabetes among this population. Therefore, we used Korea National Health and Nutrition Examination Survey (KNHANES) data to evaluate th...

journal_title：Journal of Korean medical science

authors： Cho EH,Shin D,Cho KH,Hur J

更新日期：2017-12-01 00:00:00

abstract：:The objective of this study was to develop a Korean version of the Assessment of Spondyloarthritis International Society-Health Index/Environmental Factor (ASAS HI/EF) and to evaluate its reliability and validity in Korean patients with axial spondyloarthritis (SpA). A total of 43 patients participated. Translation an...

journal_title：Journal of Korean medical science

authors： Choi JH,Kim TJ,Shin K,Choi CB,Kim JH,Kim SH,Kim NI,Ahn MJ,Jung HJ,Lee KE,Park DJ,Park YW,Lee SS,Kim TH

更新日期：2014-03-01 00:00:00

abstract：:We investigated the clinical presentations, diagnostic and therapeutic modalities, and prognosis from follow-up of infants with apparent life-threatening events (ALTE). In addition, the relationship between the clinical characteristics of patients and significant intervention scores was analyzed. We enrolled patients ...

journal_title：Journal of Korean medical science

authors： Choi HJ,Kim YH

更新日期：2015-06-01 00:00:00

abstract：:Recurrent spontaneous abortion (RSA) defines as two or more consecutive losses at < or = 20 weeks of gestation and affects an estimated 1 of every 100 couples wishing to have children. However, it remains a poorly understood phenomenon. Recent reports observed a significant association between highly skewed X chromoso...

journal_title：Journal of Korean medical science

authors： Kim JW,Park SY,Kim YM,Kim JM,Han JY,Ryu HM

更新日期：2004-04-01 00:00:00

abstract：:The overexpression of X-linked inhibitor of apoptosis protein (XIAP), a member of IAP family protein, is intuitively expected to be associated with unfavorable clinical features in malignancies; however, there have been only a very limited number of studies reporting the clinical relevance of XIAP expression. This stu...

journal_title：Journal of Korean medical science

authors： Sung KW,Choi J,Hwang YK,Lee SJ,Kim HJ,Kim JY,Cho EJ,Yoo KH,Koo HH

更新日期：2009-08-01 00:00:00

abstract：:Magnetic resonance-guided focused ultrasound (MRgFUS) is a new emerging neurosurgical procedure applied in a wide range of clinical fields. It can generate high-intensity energy at the focal zone in deep body areas without requiring incision of soft tissues. Although the effectiveness of the focused ultrasound techniq...

journal_title：Journal of Korean medical science

authors： Jung NY,Chang JW

更新日期：2018-10-04 00:00:00

abstract：:This study was done to evaluate the stemness of human mesenchymal stem cells (hMSCs) derived from placenta according to the development stage and to compare the results to those from adult bone marrow (BM). Based on the source of hMSCs, three groups were defined: group I included term placentas, group II included firs...

journal_title：Journal of Korean medical science

authors： Sung HJ,Hong SC,Yoo JH,Oh JH,Shin HJ,Choi IY,Ahn KH,Kim SH,Park Y,Kim BS

更新日期：2010-10-01 00:00:00

abstract：:Enterovirus 71 frequently involves the central nervous system and may present with a variety of neurologic manifestations. Here, we aimed to describe the clinical features, magnetic resonance imaging (MRI) findings, and cerebrospinal fluid (CSF) profiles of patients presenting with neurologic complications of enterovi...

journal_title：Journal of Korean medical science

authors： Lee KY,Lee MS,Kim DB

更新日期：2016-04-01 00:00:00

abstract：:Adult-onset Still's disease (AOSD) is an inflammatory disease that presents with a variety of clinical symptoms. Pulmonary involvement is well-known in AOSD and is seen in up to 53% of AOSD cases, with the most common pulmonary diseases being pleural effusion and transient pulmonary infiltrates. We present the first c...

journal_title：Journal of Korean medical science

authors： Sari I,Birlik M,Binicier O,Akar S,Yilmaz E,Onen F,Akkoc N

更新日期：2009-02-01 00:00:00

abstract：:Bacterial pericarditis has been recognized as a rare disease since the development of antibiotics. Usually, the disease is associated with underlying conditions or a seeding of infection elsewhere to the pericardium. Here we describe a case of group G streptococcal pericarditis as an initial presentation of colon canc...

journal_title：Journal of Korean medical science

authors： Kim NH,Park JP,Jeon SH,Lee YJ,Choi HJ,Jeong KM,Lee JG,Choi SP,Lim JH,Kim YH,Kim YS,Kim YM,Hwang MH,Cho JW,Moon Y,Oh SK,Jeong JW

更新日期：2002-08-01 00:00:00

abstract：:In 2007, the Korean Interstitial Lung Disease Society had collected clinical data of patients who have diagnosed as Lymphangioleiomyomatosis (LAM) since 1990 through nationwide survey, which showed that LAM patients had increased sharply after 2004. The present study was performed to show the clinical features of Kore...

journal_title：Journal of Korean medical science

authors： Park HY,Nam HS,Chung MP,Jeong SH,Kim YJ,Cha SI,Kim YW,Park JS,Uh ST,Park CS,Park MS,Moon JA,Jung KS,Jegal YJ,Kim DS,Song JW,Yum HK,Park YB

更新日期：2010-08-01 00:00:00

abstract：:Although pharmacological treatment constitutes the main therapeutic approach for depression, non-pharmacological treatments (self-care or psychotherapeutic approach) are usually regarded as more essential therapeutic approaches in clinical practice. However, there have been few clinical practice guidelines concerning ...

journal_title：Journal of Korean medical science

authors： Park SC,Oh HS,Oh DH,Jung SA,Na KS,Lee HY,Kang RH,Choi YK,Lee MS,Park YC

更新日期：2014-01-01 00:00:00

abstract：:Members of the inhibitors of differentiation (Id) family of helix-loop-helix (HLH) proteins are known to play important roles in the proliferation and differentiation of many cell types. Thyroid-stimulating hormone (TSH) regulates proliferation and differentiation by activating TSH receptor (TSHR) in thyrocytes. In th...

journal_title：Journal of Korean medical science

authors： Jo YS,Hwang ES,Lee JH,Lee Y,Kim SY,Choi YS,Bai YS,Hong JH,Kim YJ,Lee IS,Rha SY,Ro HK,Shong M

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:The coronavirus disease 2019 (COVID-19) outbreak has exposed healthcare workers to extreme physical workloads and psychological challenges. Thus, we aimed to assess the immediate correlates of emotional stress and to identify which specific jobs, departments, and exposure types are risk factors for emotional...

journal_title：Journal of Korean medical science

authors： Park C,Hwang JM,Jo S,Bae SJ,Sakong J

更新日期：2020-10-26 00:00:00

abstract：:The time between symptom onset and arrival at an emergency department (ED) (S2D) is a crucial time for optimal intravenous reperfusion care for ischemic stroke. We aimed to analyze the effect of emergency medical services (EMS) utilization and inter-hospital transfer on S2D in Korea. Ischemic stroke patients were pros...

journal_title：Journal of Korean medical science

authors： Park HA,Ahn KO,Shin SD,Cha WC,Ro YS

更新日期：2016-01-01 00:00:00

abstract：Background:In Korea, the incidence of varicella has increased despite the introduction of a universal one-dose vaccination for children aged 12-15 months in 2005. A previous study demonstrated that the vaccine effectiveness was insufficient to prevent against varicella. We assessed the effect of the varicella vaccinati...

journal_title：Journal of Korean medical science

authors： Lee YH,Choe YJ,Cho SI,Park H,Bang JH,Lee JK

更新日期：2019-03-07 00:00:00

abstract：:Constructing a bone marrow chimera prior to graft transplantation can induce donor-specific immune tolerance. Mixed chimerism containing hematopoietic cells of both recipient- and donor-origin has advantages attributed from low dose of total body irradiation. In this study, we explored the mechanism of mixed chimerism...

journal_title：Journal of Korean medical science

authors： Yoon IH,Kim YH,Kim YS,Shin JS,Park CG

更新日期：2013-12-01 00:00:00

abstract：:Cowden's disease, or multiple hamartoma syndrome, is an uncommon condition with characteristic mucocutaneous lesions associated with abnormalities of the breast, thyroid, and gastrointestinal tract. We describe a 32-year-old man with oral mucosal papillomatosis and plantar hyperkeratosis as a definite case of Cowden's...

journal_title：Journal of Korean medical science

authors： Lee HR,Moon YS,Yeom CH,Kim KW,Chun JY,Kim HK,Choi HS,Kim DK,Chung TS

更新日期：1997-12-01 00:00:00

abstract：:X-linked hypophosphatemic rickets (XLH) results from mutations in the PHEX gene. Mutational analysis of the PHEX gene in 15 unrelated Korean patients with hypophosphatemic rickets revealed eight mutations, including five novel mutations, in nine patients: two nonsense mutations, two missense mutations, one insertion, ...

journal_title：Journal of Korean medical science

authors： Song HR,Park JW,Cho DY,Yang JH,Yoon HR,Jung SC

更新日期：2007-12-01 00:00:00

abstract：:The safety of accelerated schedules of allergen immunotherapy (ASAI) in patients with bronchial asthma (BA) has been reported but there are little data on the safety of ASAI for patients with atopic dermatitis (AD). In this study, we investigated the safety of ASAI in patients with AD. Sixty patients with AD and 18 pa...

journal_title：Journal of Korean medical science

authors： Kim ME,Kim JE,Sung JM,Lee JW,Choi GS,Nahm DH

更新日期：2011-09-01 00:00:00

abstract：:The aim of this study was to determine the risk factors for nosocomial infections of imipenem-resistant Pseudomonas aeruginosa (IRPA). A prospective case-control study was performed at a tertiary care hospital in Ankara from January to December 2004. The patients with nosocomial P. aeruginosa infection were included i...

journal_title：Journal of Korean medical science

authors： Onguru P,Erbay A,Bodur H,Baran G,Akinci E,Balaban N,Cevik MA

更新日期：2008-12-01 00:00:00

abstract：:This research focuses on the analysis regarding disclosure of financial conflicts of interest (FCOI) after Gelsinger v. University of Pennsylvania (Penn). The main legal issue was that the participants did not have enough opportunity to make an autonomous decision about participating in the research because he was not...

journal_title：Journal of Korean medical science

authors： Kim JS

更新日期：2017-12-01 00:00:00

abstract：:Unintentional environmental exposure to toxicants is associated with an aggravated health status of the general population. Involuntary smoking (IS) exposure is one of the main routes to involuntary toxicants exposure. However, few studies have attempted to understand the environmental cadmium exposure by IS exposure ...

journal_title：Journal of Korean medical science

authors： Lee W,Lee S,Roh J,Won JU,Yoon JH

更新日期：2017-04-01 00:00:00

abstract：:Thoracic endovascular aortic repair (TEVAR) shows limitations in cases in which the aortic pathology involves the aortic arch. The study aims were to test a fenestrated aortic arch stent graft (FASG) with a preloaded catheter for the supraaortic arch vessels and to perform a preclinical study in swine to evaluate the ...

journal_title：Journal of Korean medical science

authors： Kim SP,Lee HC,Park TS,Ahn JH,Lee HW,Park JH,Oh J,Choi JH,Cha KS

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:The left internal thoracic artery (LITA) has been used as the first conduit of choice in coronary artery bypass grafting (CABG) because of excellent long-term patency and outcomes. However, no studies have examined substances other than nitric oxide that could be beneficial for the bypass conduit, native cor...

journal_title：Journal of Korean medical science

authors： Kim JS,Kim AH,Jang C,Jang IJ,Kim KB,Cho JY,Hwang HY

更新日期：2019-04-08 00:00:00