In-dental-office screening for diabetes mellitus using gingival crevicular blood.

Abstract:

BACKGROUND:Diabetes mellitus (DM) is undiagnosed in approximately 1/2 of the patients actually suffering from the disease. In addition, the prevalence of DM is more than 2x as high in patients with periodontitis when compared to periodontally healthy subjects. Thus, a high number of patients with periodontitis may have undiagnosed DM. AIM:The purpose of this pilot study was to evaluate, whether blood oozing from gingival tissues during routine periodontal examination can be used for determining glucose levels. 32 non-diabetic and 13 diabetic patients with moderate to severe periodontitis were enrolled and subjected to routine clinical periodontal examination. Periodontal pocket probing was performed using a standard force. Blood oozing from gingival tissues of anterior teeth following periodontal pocket probing was collected with the stick of a glucose self-monitoring device (Elite(R) 2000, Bayer Diagnostics GmbH, Munich). As control, fingerstick capillary blood was taken. Statistical analysis was performed by Pearson's correlation coefficient. RESULTS:The patient blood glucose levels ranged from 3.57 mmol/l to 18.01 mmol/l and the values of blood samples taken from gingiva or finger tip showed a very high intrapatient correlation (r=0.98; p<0.0001). CONCLUSION:The results suggested that blood oozing during routine periodontal examination may be used for diabetes mellitus screening in a dental office setting.

journal_name

J Clin Periodontol

authors

Beikler T,Kuczek A,Petersilka G,Flemmig TF

doi

10.1034/j.1600-051x.2002.290306.x

keywords:

subject

Has Abstract

pub_date

2002-03-01 00:00:00

pages

216-8

issue

3

eissn

0303-6979

issn

1600-051X

journal_volume

29

pub_type

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