Decreased circulating levels of von Willebrand factor after intravenous administration of a rapidly degradable hydroxyethyl starch (HES 200/0.5/6) in healthy human subjects.

abstract：:Fifteen polytrauma patients with asymmetric pulmonary contusion were treated with differential lung ventilation (DLV) for a mean of 106 hours (range 24-298, median 83). The differential time constant (Tc), compliance (Ct), inspiratory and expiratory airway resistance (Rawinsp, Rawexp) and peak-airway pressure (Pawpeak...

journal_title：Intensive care medicine

authors： Zandstra DF,Stoutenbeek CP,Bams JL

更新日期：1989-01-01 00:00:00

abstract：:In oleic acid-induced pulmonary oedema (OAPO) sequential intrapulmonary fluid accumulation occurs leading to different expiratory flow pattern in dependent lung regions. The potential effects on efficacy of high-frequency jet ventilation (HFJV, f = 3 Hz, I: E = 0.43, FiO2 = 0.4) were studied and compared with continuo...

journal_title：Intensive care medicine

authors： Hachenberg T,Wendt M,Hermeyer G,Ludwig E,Meyer J,Lawin P

更新日期：1989-01-01 00:00:00

abstract：OBJECTIVE:We tested the hypothesis that synchronization to patient effort during intermittent mandatory ventilation (SIMV), when compared to conventional unsynchronized intermittent mandatory ventilation (IMV), will decrease energy expenditure, as reflected by decreased oxygen consumption (VO2). DESIGN:We used a four-...

journal_title：Intensive care medicine

authors： Smith KM,Wahlig TM,Bing DR,Georgieff MK,Boros SJ,Mammel MC

更新日期：1997-04-01 00:00:00

abstract：OBJECTIVE:Candida spp. airway colonization could promote development of ventilator-associated pneumonia (VAP) caused by Pseudomonas aeruginosa, a potentially multidrug-resistant (MDR) bacteria, and worsen the outcome of VAP regardless of pathogen. We therefore address the question of the risk of MDR bacteria isolation ...

journal_title：Intensive care medicine

authors： Hamet M,Pavon A,Dalle F,Pechinot A,Prin S,Quenot JP,Charles PE

更新日期：2012-08-01 00:00:00

abstract：PURPOSE:We evaluated the impact of increasing tidal volume (V (t)), decreased chest wall compliance, and left ventricular (LV) contractility during intermittent positive-pressure ventilation (IPPV) on the relation between pulse pressure (PP) and LV stroke volume (SV(LV)) variation (PPV and SVV, respectively), and intra...

journal_title：Intensive care medicine

authors： Mesquida J,Kim HK,Pinsky MR

更新日期：2011-10-01 00:00:00

abstract：PURPOSE:To determine whether, during mechanical ventilation, an optimal positive end-expiratory pressure (PEEP) can be identified by measurement of regional tidal volume and compliance [V (T(reg)), C (RS(reg))]. METHODS:Sixteen anaesthetized intubated neonatal piglets underwent a stepwise vital capacity manoeuvre perf...

journal_title：Intensive care medicine

authors： Dargaville PA,Rimensberger PC,Frerichs I

更新日期：2010-11-01 00:00:00

abstract：PURPOSE:Polymyxin B-immobilized hemoperfusion (PMX-HP) is an adjuvant therapy for sepsis or septic shock that clears circulating endotoxin. Prior trials have shown that PMX-HP improves surrogate endpoints. We aimed to conduct an evidence synthesis to evaluate the efficacy and safety of PMX-HP in critically ill adult pa...

journal_title：Intensive care medicine

authors： Fujii T,Ganeko R,Kataoka Y,Furukawa TA,Featherstone R,Doi K,Vincent JL,Pasero D,Robert R,Ronco C,Bagshaw SM

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVE:To determine the cell content and purity of Ficoll-separated peripheral blood mononuclear cells and granulocyte isolates in sepsis patients compared to healthy controls. DESIGN AND SETTING:Prospective study in the adult and pediatric intensive care departments of the Erasmus University Medical Center in the ...

journal_title：Intensive care medicine

authors： van den Akker EL,Baan CC,van den Berg B,Russcher H,Joosten K,Hokken-Koelega AC,Lamberts SW,Koper JW

更新日期：2008-05-01 00:00:00

abstract：:We report a case of fatal septic shock, with hyperlactatemia and blood cultures positive for Streptococcus pneumoniae, in a 70-year-old patient. On two occasions (5 days, and 2 days before the patient's death), the relationship between oxygen delivery (DO2) and consumption (VO2) was examined in conjunction with two pr...

journal_title：Intensive care medicine

authors： Gallet D,Goudable J,Vedrinne JM,Viale JP,Annat G

更新日期：1997-01-01 00:00:00

abstract：:A 29-year-old woman suffered a cardiac arrest, due to profound hyperkalaemia, caused by the use of a potassium-containing salt substitute. She was resuscitated, but post-hypoxic brain damage occurred. Some of the sparse literature is reviewed. ...

journal_title：Intensive care medicine

authors： Schim van der Loeff HJ,Strack van Schijndel RJ,Thijs LG

更新日期：1988-01-01 00:00:00

abstract：OBJECTIVE:To determine the reliability of estimating arterial CO(2) pressure (PaCO(2)) using a recently introduced transcutaneous CO(2) pressure (PtcCO(2)) monitor in severe obese patients. DESIGN:Observational and interventional study. SETTING:District hospital with respiratory ward and bariatric surgery unit. PATI...

journal_title：Intensive care medicine

authors： Maniscalco M,Zedda A,Faraone S,Carratù P,Sofia M

更新日期：2008-07-01 00:00:00

abstract：OBJECTIVE:To compare isoflurane with midazolam for prolonged sedation in ventilated patients. DESIGN:Randomised controlled study. SETTING:General intensive care unit in university teaching hospital. PATIENTS:Sixty patients aged 17-80 years who required mechanical ventilation for more than 24 h. INTERVENTIONS:Sedati...

journal_title：Intensive care medicine

authors： Spencer EM,Willatts SM

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVE:To clarify the risk of secondary exposure of medical staff to sarin vapor in the emergency room, and to warn emergency room staffs of the hazard. DESIGN:Retrospective observational survey. SETTING:Emergency department of a university hospital in a metropolitan area of Japan. PARTICIPANTS:Fifteen doctors tr...

journal_title：Intensive care medicine

authors： Nozaki H,Hori S,Shinozawa Y,Fujishima S,Takuma K,Sagoh M,Kimura H,Ohki T,Suzuki M,Aikawa N

更新日期：1995-12-01 00:00:00

abstract：OBJECTIVE:To investigate the morphological changes in the liver in patients with organ failure and hyperbilirubinemia and to correlate them to the outcome. DESIGN:A case series prospective study. SETTING:Intensive care units of two general hospitals. PATIENTS:Twelve patients in organ failure with predominant hepatic...

journal_title：Intensive care medicine

authors： Douzinas EE,Vamvasakis E,Rigas K,Pitaridis M,Kittas C,Roussos C

更新日期：1996-06-01 00:00:00

abstract：:Conventional indices of tissue perfusion after surgery involving cardiopulmonary bypass (CPB) may not accurately reflect disordered cell metabolism. Venous hypercarbia leading to an increased veno-arterial difference in CO2 tensions (V-aCO2 gradient) has been shown to reflect critical reductions in systemic and pulmon...

journal_title：Intensive care medicine

authors： Ariza M,Gothard JW,Macnaughton P,Hooper J,Morgan CJ,Evans TW

更新日期：1991-01-01 00:00:00

abstract：OBJECTIVE:To assess the prevalence of relative adrenal insufficiency in patients successfully resuscitated after cardiac arrest, and its prognostic role in post-resuscitation disease. DESIGN AND SETTING:A prospective observational single-center study in a medical intensive care unit. PATIENTS:64 patients hospitalised...

journal_title：Intensive care medicine

authors： Pene F,Hyvernat H,Mallet V,Cariou A,Carli P,Spaulding C,Dugue MA,Mira JP

更新日期：2005-05-01 00:00:00

abstract：OBJECTIVE:To identify factors that predict outcome in patients receiving a Medical Emergency Team review. DESIGN:Prospective observational study. SETTING:Tertiary hospital. PATIENTS:Cohort of 228 patients receiving one or more Medical Emergency Team reviews during daytime hours over a 1-year-period. Control cohort o...

journal_title：Intensive care medicine

authors： Calzavacca P,Licari E,Tee A,Egi M,Haase M,Haase-Fielitz A,Bellomo R

更新日期：2008-11-01 00:00:00

abstract：:Measurements of added inspiratory work (AIW) of breathing imposed by three different CPAP systems were performed in 10 patients. One system was a continuous flow system while the two others were demand flow systems separated from respirators (Ohmeda VD 101 and Draeger CPAP 800 devices). AIW was calculated from pressur...

journal_title：Intensive care medicine

authors： Viale JP,Annat G,Percival C,Bertrand O,Motin J

更新日期：1986-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the effects of basic life support, time to first defibrillation and emergency medical service arrival time on neurologic outcome and expenses for hospital care in patients after cardiac arrest. SETTING:Large urban emergency medical services system and emergency department in a 2000-bed university...

journal_title：Intensive care medicine

authors： Bur A,Kittler H,Sterz F,Holzer M,Eisenburger P,Oschatz E,Kofler J,Laggner AN

更新日期：2001-09-01 00:00:00

abstract：:Arterial blood ketone body ratio, reflecting hepatic mitochondrial redox state, was measured in 26 brain-dead patients who were hypotensive but hemodynamically stable. All of them had substantially normal hepatic function. In 18 of the patients, blood ketone body ratio was maintained within the normal range in spite o...

journal_title：Intensive care medicine

authors： Nakatani T,Ishikawa Y,Kobayashi K,Ozawa K

更新日期：1991-01-01 00:00:00

abstract：OBJECTIVE:Infection is the most frequent cause of acute respiratory distress syndrome (ARDS). However, little is known about the influence of infection sites on ARDS. This study aimed to assess the associations of infection sites with ARDS development and mortality in critically ill infected patients. DESIGN:Prospecti...

journal_title：Intensive care medicine

authors： Sheu CC,Gong MN,Zhai R,Bajwa EK,Chen F,Thompson BT,Christiani DC

更新日期：2010-06-01 00:00:00

abstract：PURPOSE:Sedatives administered to critically ill children should be titrated to effect, because both under- and oversedation may have negative effects. We conducted a systematic review to examine reported incidences of under-, optimal, and oversedation in critically ill children receiving intensive care. METHODS:A sys...

journal_title：Intensive care medicine

authors： Vet NJ,Ista E,de Wildt SN,van Dijk M,Tibboel D,de Hoog M

更新日期：2013-09-01 00:00:00

abstract：PURPOSE:To investigate the relationship between hemoglobin (Hgb) and brain tissue oxygen tension (PbtO(2)) after severe traumatic brain injury (TBI) and to examine its impact on outcome. METHODS:This was a retrospective analysis of a prospective cohort of severe TBI patients whose PbtO(2) was monitored. The relationsh...

journal_title：Intensive care medicine

authors： Oddo M,Levine JM,Kumar M,Iglesias K,Frangos S,Maloney-Wilensky E,Le Roux PD

更新日期：2012-09-01 00:00:00

abstract：OBJECTIVE:Both serum levels of tumor necrosis factor-alpha (TNF alpha) and interleukin-6 (IL-6) and blood lactate levels in patients with septic shock have been shown to correlate with prognosis. The aim of the study was to define the relative predictive value of these measures. PATIENTS:38 hospitalized patients with ...

journal_title：Intensive care medicine

authors： Marecaux G,Pinsky MR,Dupont E,Kahn RJ,Vincent JL

更新日期：1996-05-01 00:00:00

abstract：OBJECTIVE:The purpose of the study was do describe the architecture of accretions occurring on the tips of central venous catheters (CVC). DESIGN:A conservative procedure was used followed by two different techniques of electron microscopy. SETTING AND PATIENTS:the study included 19 catheters which have been used on ...

journal_title：Intensive care medicine

authors： Poisson DM,Touquet S,Bercault N,Arbeille B

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVE:To characterize hemodynamic changes during experimental aspiration pneumonitis, paying special attention to echocardiographic assessment. DESIGN AND SETTING:Animal study in a university-based research laboratory. SUBJECTS:Fourteen mechanically ventilated New Zealand white rabbits INTERVENTIONS:We instilled...

journal_title：Intensive care medicine

authors： Fraisse A,Bregeon F,Delpierre S,Gaudart J,Payan MJ,Pugin J,Papazian L

更新日期：2007-02-01 00:00:00

abstract：OBJECTIVE:We assessed the methodological trial quality of individual randomized controlled studies on chlorhexidine silver sulfadiazine impregnated catheters and the effect on catheter-related infection (CRI). DESIGN:Only the studies identified in the Medline database from 1966 to December 2001 were considered, abstra...

journal_title：Intensive care medicine

authors： Geffers C,Zuschneid I,Eckmanns T,Rüden H,Gastmeier P

更新日期：2003-03-01 00:00:00

abstract：:Plasma colloid osmotic pressure (COP) has been calculated from both serum albumin concentration and plasma total protein concentration. These values have been compared to those measured directly using a membrane-transducer oncometer in a group of normal subjects, in a group of critically-ill patients with a variety of...

journal_title：Intensive care medicine

authors： Barclay SA,Bennett D

更新日期：1987-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the impact of two different comorbidity measures on the 6-month mortality of severely ill cancer patients. DESIGN AND SETTING:Prospective cohort study in a ten-bed oncological medical-surgical intensive care unit (ICU). PATIENTS:A total of 772 consecutive patients were included over a 45-month p...

journal_title：Intensive care medicine

authors： Soares M,Salluh JI,Ferreira CG,Luiz RR,Spector N,Rocco JR

更新日期：2005-03-01 00:00:00

abstract：:Arrhythmias are extremely common early after AMI. An arrhythmia is defined by exclusion, either because the sequence of myocardial depolarisation is other than normal or because certain arbitrary limits are exceeded. It follows that the term "arrhythmia" encompasses a complex heterogenous group. Although arrhythmias a...

journal_title：Intensive care medicine

authors： Rowlands DJ

更新日期：1978-01-01 00:00:00