Added inspiratory work of breathing during CPAP ventilation: comparison of two demand-valve devices with a continuous flow-system.

abstract：PURPOSE:We assessed feasibility and safety of extracorporeal carbon dioxide removal (ECCO2R) to facilitate ultra-protective ventilation (VT 4 mL/kg and PPLAT ≤ 25 cmH2O) in patients with moderate acute respiratory distress syndrome (ARDS). METHODS:Prospective multicenter international phase 2 study. Primary endpoint w...

journal_title：Intensive care medicine

authors： Combes A,Fanelli V,Pham T,Ranieri VM,European Society of Intensive Care Medicine Trials Group and the “Strategy of Ultra-Protective lung ventilation with Extracorporeal CO2 Removal for New-Onset moderate to severe ARDS” (SUPERNOVA) investigators

更新日期：2019-05-01 00:00:00

abstract：:The use of ultrasonography has become increasingly popular in the everyday management of critically ill patients. It has been demonstrated to be a safe and handy bedside tool that allows rapid hemodynamic assessment and visualization of the thoracic, abdominal and major vessels structures. More recently, M-mode ultras...

journal_title：Intensive care medicine

authors： Matamis D,Soilemezi E,Tsagourias M,Akoumianaki E,Dimassi S,Boroli F,Richard JC,Brochard L

更新日期：2013-05-01 00:00:00

abstract：PURPOSE:Acute heart failure (AHF) causes high burden of mortality, morbidity, and repeated hospitalizations worldwide. This guidance paper describes the tailored treatment approaches of different clinical scenarios of AHF and CS, focusing on the needs of professionals working in intensive care settings. RESULTS:Tissue...

journal_title：Intensive care medicine

authors： Mebazaa A,Tolppanen H,Mueller C,Lassus J,DiSomma S,Baksyte G,Cecconi M,Choi DJ,Cohen Solal A,Christ M,Masip J,Arrigo M,Nouira S,Ojji D,Peacock F,Richards M,Sato N,Sliwa K,Spinar J,Thiele H,Yilmaz MB,Januzzi J

更新日期：2016-02-01 00:00:00

abstract：:Two patients with chest injuries, flail chest and respiratory failure were mechanically ventilated by a system composed of 2 Bennett respirators and an independent source of gas. This system provides high-frequency positive pressure ventilation (HFPPV), low-frequency conventional mechanical ventilation (LFCMV) and hig...

journal_title：Intensive care medicine

authors： Barzilay E,Lev A,Lesmes C,Fleck R,Khourieh A

更新日期：1984-01-01 00:00:00

abstract：PURPOSE:Neurologic and endothelial injury biomarkers are associated with prolonged delirium during critical illness and may reflect injury pathways that lead to poor long-term outcomes. We hypothesized that blood-brain barrier (BBB), neuronal, and endothelial injury biomarkers measured during critical illness are assoc...

journal_title：Intensive care medicine

authors： Hughes CG,Patel MB,Brummel NE,Thompson JL,McNeil JB,Pandharipande PP,Jackson JC,Chandrasekhar R,Ware LB,Ely EW,Girard TD

更新日期：2018-03-01 00:00:00

abstract：:Controlled mechanical ventilation is an accepted therapy for acute respiratory failure but by virtue of the increase in intrathoracic pressure has a large number of disadvantages. It is to overcome these disadvantages that alternative modes of ventilation have been introduced. These aim to reduce the effects of abnorm...

journal_title：Intensive care medicine

authors： Willatts SM

更新日期：1985-01-01 00:00:00

abstract：OBJECTIVE:To analyze the effect of endothelin-1 on pulmonary arterial and venous contractile force in vitro and on up- and downstream pulmonary vascular resistance in vivo under sham and endotoxemic conditions in pigs. MATERIALS AND METHODS:In vitro: paired preparations of pulmonary arteries and veins were mounted in ...

journal_title：Intensive care medicine

authors： Rossi P,Persson B,Boels PJ,Arner A,Weitzberg E,Oldner A

更新日期：2008-05-01 00:00:00

abstract：OBJECTIVE:To determine the clinical impact of bedside colonoscopy for critically ill patients with acute lower gastrointestinal (GI) bleeding. DESIGN AND SETTING:A 3-year retrospective analysis (chart review). Medical intensive care unit (ICU) of a 1,312-bed tertiary-care center in Taiwan. PATIENTS AND PARTICIPANTS:F...

journal_title：Intensive care medicine

authors： Lin CC,Lee YC,Lee H,Lin JT,Ho WC,Chen TH,Wang HP

更新日期：2005-05-01 00:00:00

abstract：:The side effects of positive pressure ventilation on cardiovascular function are well known. However, in most clinical studies its influence on left ventricular function was examined. In the present study right ventricular (RV) performance was studied in 13 patients undergoing coronary artery bypass grafting during me...

journal_title：Intensive care medicine

authors： Neidhart PP,Suter PM

更新日期：1988-01-01 00:00:00

abstract：OBJECTIVE:To validate a simple method avoiding discard volumes in pediatric patients with indwelling arterial and venous lines. DESIGN:Zero-discarding was achieved by passive extracorporeal arteriovenous backflow via standard single pressure transducer equipment. We tested backflow distances (10, 20 and 30 cm beyond t...

journal_title：Intensive care medicine

authors： Weiss M,Fischer J,Boeckmann M,Rohrer B,Baenziger O

更新日期：2001-06-01 00:00:00

abstract：OBJECTIVE:To determine if the plasma levels of three endothelial-specific proteins, von Willebrand factor (vWF), tissue factor pathway inhibitor (TFPI) and thrombomodulin (TM) may be useful in predicting the development of acute respiratory distress syndrome (ARDS). DESIGN:Blood samples were obtained from normal healt...

journal_title：Intensive care medicine

authors： Bajaj MS,Tricomi SM

更新日期：1999-11-01 00:00:00

abstract：:Acute renal failure in critically ill patients is seldom an isolated problem but is more usually associated with multiple organ failure. When choosing an extracorporeal kidney replacement therapy, these other failing organs must be taken into account. Therefore the choice of an artificial kidney in patients requiring ...

journal_title：Intensive care medicine

authors： Schetz M,Lauwers PM,Ferdinande P

更新日期：1989-01-01 00:00:00

abstract：OBJECTIVE:To assess noise exposure during noninvasive ventilation (NIV) with different types of interface (helmet, nasal, and facial masks). SUBJECTS AND METHODS:Ten "naive" healthy volunteers underwent NIV at pressure support levels of 10 and 15 cmH2O with: (a) helmet, (b) helmet equipped with HME filters at the junc...

journal_title：Intensive care medicine

authors： Cavaliere F,Conti G,Costa R,Proietti R,Sciuto A,Masieri S

更新日期：2004-09-01 00:00:00

abstract：:Two hundred and seventy-three acute hemorrhagic shocks were treated in 1984 in a pre-hospital emergency care unit. Twenty patients (7%) had a paradoxical bradycardia: they were conscious, 9 of them had an undetectable systolic arterial pressure with the sphygmomanometric method but the femoral pulse was still present....

journal_title：Intensive care medicine

authors： Barriot P,Riou B

更新日期：1987-01-01 00:00:00

abstract：OBJECTIVES:To establish priorities for research in critical care medicine in the UK using survey and nominal group (NG) techniques. DESIGN:The senior doctor and nurse from 325 intensive care units (ICUs) in the UK were invited to contribute up to ten research questions relevant to intensive care organisation, practice...

journal_title：Intensive care medicine

authors： Goldfrad C,Vella K,Bion JF,Rowan KM,Black NA

更新日期：2000-10-01 00:00:00

abstract：OBJECTIVE:To determine the incidence of Clostridium difficile (CD) diarrhoea in feed-intolerant, critically ill patients who received erythromycin-based prokinetic therapy. DESIGN AND SETTING:Prospective observational study in a mixed intensive care unit. METHODS:The development of diarrhoea (> 3 loose, liquid stool ...

journal_title：Intensive care medicine

authors： Nguyen NQ,Ching K,Fraser RJ,Chapman MJ,Holloway RH

更新日期：2008-01-01 00:00:00

abstract：:We describe a case of the dialysis disequilibrium syndrome (DDS) that was marked by the rapid onset of cerebral edema and the subsequent development of acute respiratory failure. The patient was treated successfully with a combination of mechanical hyperventilation and mannitol. The clinical presentation, pathogenesis...

journal_title：Intensive care medicine

authors： DiFresco V,Landman M,Jaber BL,White AC

更新日期：2000-05-01 00:00:00

abstract：: ...

journal_title：Intensive care medicine

authors： Hawryluck L,Brindley PG

更新日期：2018-12-01 00:00:00

abstract：PURPOSE:Protective mechanical ventilation based on multiple ventilator parameters such as tidal volume, plateau pressure, and driving pressure has been widely used in acute respiratory distress syndrome (ARDS). More recently, mechanical power (MP) was found to be associated with mortality. The study aimed to investigat...

journal_title：Intensive care medicine

authors： Zhang Z,Zheng B,Liu N,Ge H,Hong Y

更新日期：2019-06-01 00:00:00

abstract：OBJECTIVE:Biomarkers allowing accurate early staging of septic shock patients are lacking despite their obvious interest for patient management. Experimental models of septic shock in mouse previously noted a decrease in dendritic cell numbers. The aim of the study was to find a rapid reproducible biological test for a...

journal_title：Intensive care medicine

authors： Guisset O,Dilhuydy MS,Thiébaut R,Lefèvre J,Camou F,Sarrat A,Gabinski C,Moreau JF,Blanco P

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVE:Transcapillary heat transfer after injections of cold saline into the right atrium generates bronchial thermodilution curves resembling those observed in the aorta. Under the assumption that no indicator is lost or gained within the pulmonary capillary bed and changes in blood temperature are instantaneously ...

journal_title：Intensive care medicine

authors： Loer SA,Wietasch JK,Scheeren TW

更新日期：1999-02-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to investigate the effect of lung volume changes on end-expiratory lung impedance change (ELIC) in mechanically ventilated patients, since we hypothesized that ELIC may be a suitable parameter to monitor lung volume change at the bedside. DESIGN:Clinical trial on patients requiring m...

journal_title：Intensive care medicine

authors： Hinz J,Hahn G,Neumann P,Sydow M,Mohrenweiser P,Hellige G,Burchardi H

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:Cytokeratin 19 (CK19) is a specific cytoskeletal structure for alveolar epithelium. We hypothesized that the levels of CK19 fragments in bronchoalveolar lavage (BAL) fluid could serve as an index of epithelial injury and as a prognosis marker in patients with acute lung injury (ALI) or acute respiratory distr...

journal_title：Intensive care medicine

authors： Stern JB,Paugam C,Validire P,Adle-Biassette H,Jaffré S,Dehoux M,Crestani B

更新日期：2006-06-01 00:00:00

abstract：OBJECTIVES:To analyse the clinical value of procalcitonin (PCT), C-reactive protein (CRP) and leucocyte count in the diagnosis of paediatric sepsis and in the stratification of patients according to severity. DESIGN:Prospective, observational study. SETTING:Paediatric intensive care unit (PICU). PATIENTS:Ninety-four...

journal_title：Intensive care medicine

authors： Rey C,Los Arcos M,Concha A,Medina A,Prieto S,Martinez P,Prieto B

更新日期：2007-03-01 00:00:00

abstract：:A randomized study of 30 patients undergoing uncomplicated surgery under spinal anesthesia was conducted to assess the influence of colloids on the kinetics of plasma fibronectin and complement. Both are opsonins of the reticuloendothelial system; moreover fibronectin is concerned with host resistance against septic c...

journal_title：Intensive care medicine

authors： Vedrinne JM,Hoen JP,Bussery D,Veyssere C,Richard M,Motin J

更新日期：1991-01-01 00:00:00

abstract：:Total extracorporeal lung assist (ECLA) requires a bypass flow approaching cardiac output. Recirculation of venous blood through the oxygenator is minimized with a veno-right ventricular cannulation technique which separates venous drainage from returned oxygenated blood. A case of posttraumatic ARDS was treated with ...

journal_title：Intensive care medicine

authors： Wetterberg T,Steen S

更新日期：1991-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the use of antidotal therapy in patients with an elevated digitalis concentration following chronic or acute exposure. DESIGN AND SETTING:Retrospective review of patient records over 2 years in 20 city hospitals in France. PATIENTS:Overall 838 patients with an elevated serum digitalis concentrat...

journal_title：Intensive care medicine

authors： Lapostolle F,Borron SW,Verdier C,Arnaud F,Couvreur J,Mégarbane B,Baud F,Adnet F

更新日期：2008-08-01 00:00:00

abstract：:The case of an 11-year-old boy who suffered second and third degree burns to 78% of his body is reported. The large doses of morphine used as analgesia resulted in severe side effects: ventilatory dependence, impairment of gastrointestinal function and psychological disturbance. Intravenous lignocaine was added withou...

journal_title：Intensive care medicine

authors： Lyons B,Casey W,Doherty P,McHugh M,Moore KP

更新日期：1996-03-01 00:00:00

abstract：OBJECTIVE:Invasive candidiasis (IC) outcomes in intensive care units (ICUs) could be improved by the early administration of antifungals. The Candida Score (CS) prediction rule has been proposed for the selection of patients who could develop IC. Procalcitonin (PCT) levels allow prompt identification of sepsis, but the...

journal_title：Intensive care medicine

authors： Charles PE,Castro C,Ruiz-Santana S,León C,Saavedra P,Martín E

更新日期：2009-12-01 00:00:00

abstract：PURPOSE:To compare characteristics, clinical evolution and outcome in adult patients with influenza A (H1N1) acute respiratory distress syndrome (ARDS) treated with or without extracorporeal membrane oxygenation (ECMO). METHODS:A prospective observational study of patients treated in Marseille South Hospital from Octo...

journal_title：Intensive care medicine

authors： Roch A,Lepaul-Ercole R,Grisoli D,Bessereau J,Brissy O,Castanier M,Dizier S,Forel JM,Guervilly C,Gariboldi V,Collart F,Michelet P,Perrin G,Charrel R,Papazian L

更新日期：2010-11-01 00:00:00