FERMing up the synapse.

Abstract:

:The immunological synapse is characterized by the reorganization of membrane proteins at the immunological synapse. Active cytoskeletal mechanisms are involved in recruiting the TCR, accessory molecules, and the integrin LFA-1 to the contact area. Other molecules like CD43 are excluded from the contact area, but the mechanism of exclusion is unknown. Three papers in this issue of Immunity demonstrate that CD43 exclusion involves the ERM family of cytoskeletal proteins.

journal_name

Immunity

journal_title

Immunity

authors

Shaw AS

doi

10.1016/s1074-7613(01)00237-0

keywords:

subject

Has Abstract

pub_date

2001-11-01 00:00:00

pages

683-6

issue

5

eissn

1074-7613

issn

1097-4180

pii

S1074-7613(01)00237-0

journal_volume

15

pub_type

杂志文章,评审

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