Abstract：
:A green button may be the target of a movement, or it may instruct the opening of an adjacent door. In the first case, its spatial configuration serves to guide the hand, whereas in the second case its colour allows a decision between alternative courses of action. This study contrasts these two categories of visuomotor transformation. Our goal was to test the hypothesis that visual information can influence the motor system through different, task-dependent pathways. We used positron emission tomography (PET) to measure human brain activity during the performance of two tasks requiring the transformation of visual stimuli to motor responses. The stimuli instructed either a spatially congruent grasping movement or an arbitrarily associated hand movement. The experimental design emphasised preparatory- over movement-related activity. We expected ventral parieto-precentral regions to contribute to the visuomotor transformations underlying grasping movements, and fronto-striatal circuitry to contribute to the selection of actions on the basis of associative rules. We found that selecting between alternative courses of action on the basis of associative rules specifically involved ventral prefrontal, striatal and dorsal precentral areas. Conversely, spatially congruent grasping movements evoked specific differential responses in ventral precentral and parietal regions. The results suggest that visual information can flow through the dorsal system to determine how actions are performed, but that fronto-striatal loops are involved in specifying which action should be performed in the current context.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Toni I,Rushworth MF,Passingham REdoi
10.1007/s002210100877keywords:
subject
Has Abstractpub_date
2001-12-01 00:00:00pages
359-69issue
3eissn
0014-4819issn
1432-1106journal_volume
141pub_type
杂志文章abstract：:Two rhesus monkeys were trained to make saccadic eye movements from a central fixation point towards a peripheral target. Saccadic reaction times (SRTs) were measured in the gap paradigm (200 ms pause between offset of fixation point and onset of peripheral target). Target position for extensive training (SRTs of 150 ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00230109
更新日期：1990-01-01 00:00:00
abstract：:When reaches are performed toward target objects, the presence of other non-target objects influences kinematic parameters of the reach. A typical observation has been that non-targets positioned ipsilaterally to the acting limb interfere more with the trajectory of the hand than contralateral non-targets. Here, we in...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-013-3615-0
更新日期：2013-09-01 00:00:00
abstract：:The fluorescent dye diamidino yellow was injected into parts of the developing visual and auditory systems in the rat. The dye was retrogradely transported by projecting neurones and was found to stain pyknotic profiles within the labelled cell populations. It is thus possible to visualize directly the death of neuron...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00228865
更新日期：1990-01-01 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-004-1833-1
更新日期：2004-07-01 00:00:00
abstract：:The effects of electrical stimulation within the midbrain on fusimotor output to the jaw elevator muscles were studied in anaesthetized cats. Muscle spindle afferents recorded in the mesencephalic trigeminal nucleus were categorised as primary or secondary by their responses to succinylcholine during sinusoidal or ram...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00227778
更新日期：1993-01-01 00:00:00
abstract：:Changes in cognition due to age have been associated with falls and reduced standing postural control. Sensory integration is one component of postural control that may be influenced by certain aspects of cognitive functioning. This study investigated associations between measures of cognitive function and sensory int...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-018-5394-0
更新日期：2019-01-01 00:00:00
abstract：:Peak grip aperture has often been used to quantify the influence of illusions on judgments of size for action. However, a larger peak grip aperture need not mean that the object looks larger. It could also mean that it was grasped more carefully. These two possibilities can be distinguished on the basis of the velocit...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-006-0744-8
更新日期：2007-01-01 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210000544
更新日期：2000-12-01 00:00:00
abstract：:The literature reports that anticipatory postural adjustments (APAs) are programmed according to movement velocity. However, the linkage between APAs and velocity has been highlighted within single subjects who were asked to voluntarily change movement velocity; therefore, till now, it has been impossible to discern w...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-014-4122-7
更新日期：2015-02-01 00:00:00
abstract：:When someone grasps an object, the grasp depends on the intended object manipulation and usually facilitates it. If several object manipulation steps are planned, the first step has been reported to primarily determine the grasp selection. We address whether the grasp can be aligned to the second step, if the second s...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-017-4892-9
更新日期：2017-05-01 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00228892
更新日期：1990-01-01 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-013-3781-0
更新日期：2014-05-01 00:00:00
abstract：:In order to investigate the role of mental rotation in the directional control of eye movements, we instructed subjects to make saccades in directions different from that of a visual stimulus (rotated saccades). Saccadic latency increased linearly with the amount of directional transformation imposed between the stimu...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210050765
更新日期：1999-06-01 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00237218
更新日期：1982-01-01 00:00:00
abstract：:Extracellular single-unit recordings were made during day- and night-time in the pineal gland of urethane-anesthetized adult male Sprague-Dawley rats. All cells exhibiting spontaneous electrical activity had firing frequencies from less than 1 Hz to about 100 Hz, and their discharge patterns were characterized as regu...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00235276
更新日期：1984-01-01 00:00:00
abstract：:A photographic technique was used to study the evolution of lateral head-tilt following hemilabyrinthectomy in adult cats. Animals were maintained post-operatively in normally lit conditions (LM cats), in total darkness (DM cats), or in stroboscopic light. In LM casts, the head tilt peaked at 45 degrees (with the lesi...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00235707
更新日期：1977-06-27 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00241358
更新日期：1995-01-01 00:00:00
abstract：:Nociceptive suppression of tonic voluntary electromyographic (EMG) activity in human hand muscles (cutaneous silent period, CSP) is in its functional organization consistent with a spinal protective reflex. Motoneuronal excitability and its modulation may also be investigated by conditioned motor evoked potentials (ME...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-008-1372-2
更新日期：2008-07-01 00:00:00
abstract：:Efficient daily navigation is underpinned by path integration, the mechanism by which we use self-movement information to update our position in space. This process is well understood in adulthood, but there has been relatively little study of path integration in childhood, leading to an underrepresentation in account...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-013-3709-8
更新日期：2013-12-01 00:00:00
abstract：:The activity of 28 cells located mainly in the secondary auditory cortex (A II) of awake squirrel-monkeys, was extracellularly recorded for periods of up to 6 h. Seven different species-specific vocalizations, which were repeatedly presented to the monkey, were used as auditory stimuli. Twenty-six cells responded, at ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00239144
更新日期：1979-02-15 00:00:00
abstract：:The startle reaction (SR) is usually understood as an involuntary reaction to an unexpected sensory input. However, there is evidence that the mechanisms involved in the SR contribute also to the execution of actions that we consider voluntary. We need to exert a fine control of the motor output, which usually involve...
journal_title：Experimental brain research
pub_type： 杂志文章,评审
doi：10.1007/s00221-008-1402-0
更新日期：2008-06-01 00:00:00
abstract：:The effect of fatigue on finger force perception within a hand during ipsilateral finger force matching was examined. Thirteen subjects were instructed to match a reference force of an instructed finger using the same or different finger within the hand before and after index finger fatigue. Absolute reference force t...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-007-0978-0
更新日期：2007-09-01 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00235671
更新日期：1979-01-15 00:00:00
abstract：:The affect-modulated startle response is a reliable indicator of the affective processing of stimuli. It may be influenced by trait and state affective variables as well as psychopathological status. The aim of the present study was to determine the influence of the current mood state on startle modulation. Forty-five...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-006-0653-x
更新日期：2007-02-01 00:00:00
abstract：:Empathy, i.e., the ability to perceive and share another person's affective state, is associated with activity in a complex neural network, including the anterior insula, the anterior and mid-cingulate cortex, and the lateral prefrontal cortex. Here, we were interested in the question how facial emotions influence the...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-016-4731-4
更新日期：2016-11-01 00:00:00
abstract：:We describe the simple-spike activity of Purkinje cells (P cells) in the ventral paraflocculus (VPFL) of behaving monkeys in association with movements of the visual scene that evoke short-latency ocular following responses. One group of P cells discharged maximally for downward motion, and the other for motion toward...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00228385
更新日期：1993-01-01 00:00:00
abstract：:In one of the most-widely used species in pineal gland research, the strongly photoperiodic golden hamster, Mesocricetus auratus, no electrophysiological data on pinealocytes are currently available. To fill this gap, in the present study 185 spontaneously active pinealocytes from male golden hamsters were recorded ex...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00269449
更新日期：1987-01-01 00:00:00
abstract：:This study investigated the modulation of somatosensory evoked potentials (SEPs) during precisely controlled force generation and force relaxation in a visuomotor tracking task. Subjects were instructed to track a target line with a line that represented their own force generated by grip movement with the right hand a...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-012-3082-z
更新日期：2012-06-01 00:00:00
abstract：:We have monitored extracellularly individual neurons in the striate cortex of 4-week-old unparalyzed kittens with the aim of changing the ocular dominance of these cells during recording. To do this, we elicited conjugate eye movements using a bipolar stimulating electrode positioned in the internal medullary lamina (...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00236575
更新日期：1981-01-01 00:00:00
abstract：:Human subjects can readily adapt their movement trajectories to different dynamic or visuomotor environments. The focus of the current study was to determine whether subjects could simultaneously adapt to multiple dynamic environments. Subjects ( n=5) drew ellipses continuously for 70 s using a torquable manipulandum ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-002-1260-0
更新日期：2003-01-01 00:00:00
