Abstract:
:The affect-modulated startle response is a reliable indicator of the affective processing of stimuli. It may be influenced by trait and state affective variables as well as psychopathological status. The aim of the present study was to determine the influence of the current mood state on startle modulation. Forty-five healthy volunteers viewed affective stimuli while eye blink responses and subjective emotional ratings were assessed. In addition, the current state of mood was assessed, pre and post the experimental procedure. Subjects were divided into those that were in a more positive and those that were in a more negative mood based on a median split. Compared to subjects in a positive mood those in a more negative mood showed significantly reduced startle amplitudes after viewing the negative and neutral stimuli. The results of the present study show that changes in startle responses are not only related to the current state of psychopathology but also to the general affective state of the participants during the assessments.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Grüsser SM,Wölfling K,Mörsen CP,Kathmann N,Flor Hdoi
10.1007/s00221-006-0653-xsubject
Has Abstractpub_date
2007-02-01 00:00:00pages
122-8issue
1eissn
0014-4819issn
1432-1106journal_volume
177pub_type
杂志文章abstract::Short interval intracortical inhibition (SICI) is a common paired-pulse TMS technique that is used to measure GABAa-ergic inhibition in the cerebral motor cortex. However, inhibition evaluated with an interstimulus interval (ISI) between the TMS pulses of 2.5 ms has quite different properties from that seen at 1 ms. I...
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