Measurement of single kidney contrast media clearance by multiphasic spiral computed tomography: preliminary results.


OBJECTIVE:We present preliminary results of a new method (hereinafter called 'CT-clearance') to measure single kidney contrast media clearance by performing multiphasic helical CT of the kidneys. CT-clearance was calculated according to an extension of the Patlak-Plot. In contrast to prior investigators, who repeatedly measured a single slice, this method makes it possible to calculate single kidney clearance from at least three spiral CTs, utilizing the whole kidney volume. METHODS:Spiral CT of the kidneys was performed unenhanced and about 30 and 100 s after administration of about 120 ml iopromide. Sum-density of the whole kidneys and aortic density was calculated from this data. Using this data, renal clearance of contrast media was calculated by CT-clearance in 29 patients. As reference, Serum-clearance was calculated in 24 patients by application of a modified one-exponential slope model. Information on the relative kidney function was gained by renal scintigraphy with Tc99m-MAG-3 or Tc99m-DMSA in 29 patients. RESULTS:Linear regression analysis revealed a correlation coefficient of CT-clearance with Serum-clearance of r=0.78 with Cl (CT) [ml/min]=22.2+1.03 * Cl (serum), n=24. Linear regression of the relative kidney function (rkf) of the right kidney calculated by CT-clearance compared to scintigraphy results provided a correlation coefficient r=0.89 with rkf(CT)[%]=18.6+0.58 * rkf(scintigraphy), n=29. CONCLUSION:The obtained results of contrast media clearance measured by CT-clearance are in the physiological range of the parameter. Future studies should be performed to improve the methodology with the aim of higher accuracy. More specifically, better determination of the aortic density curve might improve the accuracy.


Eur J Radiol


Hackstein N,Puille MF,Bak BH,Scharwat O,Rau WS





Has Abstract


2001-09-01 00:00:00














  • From protein-protein interaction to therapy response: molecular imaging of heat shock proteins.

    abstract::HSP70 promoter-driven gene therapy and inhibition of HSP90 activity with small molecule inhibitors are two shining points in a newly developed cohort of cancer treatment. For HSP70 promoters, high efficiency and heat inducibility within a localized region make it very attractive to clinical translation. The HSP90 inhi...

    journal_title:European journal of radiology

    pub_type: 杂志文章,评审


    authors: Niu G,Chen X

    更新日期:2009-05-01 00:00:00

  • Value of MR-based radiomics in differentiating uveal melanoma from other intraocular masses in adults.

    abstract:PURPOSE:To assess the performance of machine learning (ML)-based magnetic resonance imaging (MRI) radiomics analysis for discriminating between uveal melanoma (UM) and other intraocular masses. METHODS:This retrospective study analyzed 245 patients with intraocular masses (165 UMs and 80 other intraocular masses). Rad...

    journal_title:European journal of radiology

    pub_type: 杂志文章


    authors: Su Y,Xu X,Zuo P,Xia Y,Qu X,Chen Q,Guo J,Wei W,Xian J

    更新日期:2020-10-01 00:00:00

  • Pelvimetry revisited: analyzing cephalopelvic disproportion.

    abstract::The objective of this study was to assess the clinical value of pelvimetry to predict dystocia due to cephalopelvic disproportion. 63 patients who had received an abdominal CT scan postpartum were included. Pelvimetry was performed retrospectively with these datasets on a 3D workstation; there were no CT examinations ...

    journal_title:European journal of radiology

    pub_type: 杂志文章


    authors: Lenhard MS,Johnson TR,Weckbach S,Nikolaou K,Friese K,Hasbargen U

    更新日期:2010-06-01 00:00:00

  • Depiction of normal gastrointestinal anatomy with MDCT: comparison of low- and high-attenuation oral contrast media.

    abstract:PURPOSE:To compare low- and high-attenuation oral contrast media for depiction of normal gastrointestinal anatomy with multidetector-row computed tomography (MDCT). MATERIALS AND METHODS:A prospective, randomized study of 90 consecutive patients without known or suspected gastrointestinal disease was conducted after t...

    journal_title:European journal of radiology

    pub_type: 杂志文章,随机对照试验


    authors: Erturk SM,Mortelé KJ,Oliva MR,Ichikawa T,Silverman SG,Cantisani V,Pagliara E,Ros PR

    更新日期:2008-04-01 00:00:00

  • Diagnostic image workstations for PACS.

    abstract::Image workstations will be the 'window' to the complex infrastructure of a PACS with its intertwined image modalities (image sources, image data bases and image processing devices) and data processing modalities (patient data bases, departmental and hospital information systems). They will serve for user-to-system dia...

    journal_title:European journal of radiology

    pub_type: 杂志文章


    authors: Meyer-Ebrecht D,Fasel B,Dahm M,Kaupp A,Schilling T

    更新日期:1990-05-01 00:00:00

  • Differentiating benign from malignant solid breast lesions: combined utility of conventional ultrasound and contrast-enhanced ultrasound in comparison with magnetic resonance imaging.

    abstract:OBJECTIVE:To prospectively evaluate the diagnostic efficacy of conventional ultrasound (US), contrast-enhanced US (CEUS), the combined use of two modalities, and magnetic resonance imaging (MRI) in the differentiation of focal solid breast lesions. MATERIALS AND METHODS:61 patients with BI-RADS category 3-5 breast les...

    journal_title:European journal of radiology

    pub_type: 杂志文章


    authors: Du J,Wang L,Wan CF,Hua J,Fang H,Chen J,Li FH

    更新日期:2012-12-01 00:00:00

  • Quantitative 3D pulmonary MR-perfusion in patients with pulmonary arterial hypertension: correlation with invasive pressure measurements.

    abstract:PURPOSE:Pathological changes of the peripheral pulmonary arteries induce pulmonary arterial hypertension (PAH). Aim of this study was to quantitatively assess the effect of PAH on pulmonary perfusion by 3D-MR-perfusion techniques and to compare findings to healthy controls. Furthermore, quantitative perfusion data were...

    journal_title:European journal of radiology

    pub_type: 杂志文章


    authors: Ley S,Mereles D,Risse F,Grünig E,Ley-Zaporozhan J,Tecer Z,Puderbach M,Fink C,Kauczor HU

    更新日期:2007-02-01 00:00:00

  • Complications of pneumoconiosis: radiologic overview.

    abstract::A wide spectrum of pulmonary complications occurs in patients with pneumoconiosis. Those complications include chronic obstructive pulmonary disease, hemoptysis, pneumothorax, pleural disease, tuberculosis, autoimmune disease, anthracofibrosis, chronic interstitial pneumonia, and malignancy. Generally, imaging workup ...

    journal_title:European journal of radiology

    pub_type: 杂志文章,评审


    authors: Jun JS,Jung JI,Kim HR,Ahn MI,Han DH,Ko JM,Park SH,Lee HG,Arakawa H,Koo JW

    更新日期:2013-10-01 00:00:00

  • When the diameter of the abdominal aorta should be considered as abnormal? A new ultrasonographic index using the wrist circumference as a body build reference.

    abstract:PURPOSE:To use US to evaluate the normal values of aortic diameter (AD), stratifying the population by age, gender and body build, as measured using wrist circumference (WC). MATERIALS AND METHODS:Between April 2010 and February 2012, consecutive patients ≥ 30 years of age, without history of abdominal aortic aneurysm...

    journal_title:European journal of radiology

    pub_type: 杂志文章


    authors: Sconfienza LM,Santagostino I,Di Leo G,Piazza R,Gozzi G,Trimarchi S,Sardanelli F

    更新日期:2013-10-01 00:00:00

  • How fast can we scan patients with modern (digital) PET/CT systems?

    abstract:PURPOSE:To seek for the minimal duration per bed position with a digital PET system without compromising image quality and lesion detection in patients requiring fast 18F-FDG PET imaging. MATERIALS AND METHODS:19 cancer patients experiencing pain or dyspnea and 9 pediatric patients were scanned on a Vereos system. Lis...

    journal_title:European journal of radiology

    pub_type: 杂志文章


    authors: Lasnon C,Coudrais N,Houdu B,Nganoa C,Salomon T,Enilorac B,Aide N

    更新日期:2020-08-01 00:00:00

  • WITHDRAWN: Endorectal MRI accuracy in auguring tumour location, tumour extent, capsular perforation and seminal vesicle invasion of prostate cancer in north-African men.

    abstract::This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at ...

    journal_title:European journal of radiology

    pub_type: 杂志文章


    authors: Janane A,Hajji F,Ismail TO,Elondo JC,Ghadouane M,Ameur A,Abbar M

    更新日期:2011-01-26 00:00:00

  • Dynamic high-resolution ultrasound of the shoulder: how we do it.

    abstract::Ultrasonography (US) is an established and well-accepted modality that can be used to evaluate articular and peri-articular structures around the shoulder. US has been proven to be useful in a wide range of rotator cuff diseases (tendon tears, tendinosis, and bursitis) as well as non-rotator cuff abnormalities (instab...

    journal_title:European journal of radiology

    pub_type: 杂志文章,评审


    authors: Corazza A,Orlandi D,Fabbro E,Ferrero G,Messina C,Sartoris R,Perugin Bernardi S,Arcidiacono A,Silvestri E,Sconfienza LM

    更新日期:2015-02-01 00:00:00

  • Minimally invasive therapy for the treatment of breast tumours.

    abstract::Minimally invasive therapy has been explored as a potential means of treating breast tumours with minimal disruption to adjacent soft tissues. The purpose of this is to facilitate improved cosmesis and to offer treatment to women who are unfit for surgery. A number of treatment modalities including thermal therapies (...

    journal_title:European journal of radiology

    pub_type: 杂志文章,评审


    authors: Hall-Craggs MA,Vaidya JS

    更新日期:2002-04-01 00:00:00

  • Clinical evaluation of a computer simulated prediction model of contrast enhancement of the liver in spiral CT.

    abstract:OBJECTIVE:A software program was developed simulating a compartmental model of blood circulation based on differential equations. The aim of this study was to compare software-simulated levels of hepatic enhancement with the true values in patients and to test how many patients reach the simulated hepatic enhancement l...

    journal_title:European journal of radiology

    pub_type: 杂志文章


    authors: Schöber W,Kopp A,Scherf C,Mehnert F,Heuschmid M,Duda SH,Claussen CD,Pereira P

    更新日期:2004-07-01 00:00:00

  • Textural differences between renal cell carcinoma subtypes: Machine learning-based quantitative computed tomography texture analysis with independent external validation.

    abstract:OBJECTIVE:To develop externally validated, reproducible, and generalizable models for distinguishing three major subtypes of renal cell carcinomas (RCCs) using machine learning-based quantitative computed tomography (CT) texture analysis (qCT-TA). MATERIALS AND METHODS:Sixty-eight RCCs were included in this retrospect...

    journal_title:European journal of radiology

    pub_type: 杂志文章


    authors: Kocak B,Yardimci AH,Bektas CT,Turkcanoglu MH,Erdim C,Yucetas U,Koca SB,Kilickesmez O

    更新日期:2018-10-01 00:00:00

  • Generalized diffraction enhanced imaging: application to tomography.

    abstract::A simple generalization of the diffraction enhanced imaging (DEI) technique, called generalized DEI (GDEI), and its application to tomographic imaging are herein presented. In planar imaging, the GDEI algorithm combines three input images (acquired at different analyzer positions) to deliver three parametric images, p...

    journal_title:European journal of radiology

    pub_type: 杂志文章


    authors: Rigon L,Astolfo A,Arfelli F,Menk RH

    更新日期:2008-12-01 00:00:00

  • Gastrointestinal ultrasound in neonates, infants and children.

    abstract::Today US plays an important and increasing role in the assessment of many, partially age-specific conditions in the GI tract in neonates, infants and children. Knowledge of the potential capabilities of US and its restrictions together with a skillful performance of GI US examination can provide essential anatomic and...

    journal_title:European journal of radiology

    pub_type: 杂志文章,评审


    authors: Lobo ML,Roque M

    更新日期:2014-09-01 00:00:00

  • Reproducibility--an important factor determining the quality of computer-aided detection (CAD) systems.

    abstract:PURPOSE:To test the reproducibility of markings on mammography films set by a commercial computer aided detection (CAD) system. PATIENTS AND METHODS:One hundred unilateral mammography examinations (each in CC and MLO) of 100 patients with mammographically detected suspicious foci, which were histopathologically proven...

    journal_title:European journal of radiology

    pub_type: 杂志文章


    authors: Malich A,Azhari T,Böhm T,Fleck M,Kaiser WA

    更新日期:2000-12-01 00:00:00

  • Preablation three-dimensional ultrasonography can predict therapeutic effect and local tumor progression after radiofrequency ablation for hepatocellular carcinoma.

    abstract:PURPOSE:To assess the agreement between ablative margin (AM) predicted by preablation three-dimensional ultrasonography (3D-US) and AM measured on postablation computed tomography (CT)/magnetic resonance (MR) images. METHODS:Sixty patients with 73 hepatocellular carcinoma nodules were enrolled. 3D-US data were collect...

    journal_title:European journal of radiology

    pub_type: 杂志文章


    authors: Matsuki Y,Matono T,Koda M,Miyoshi K,Sugihara T,Okano JI,Isomoto H

    更新日期:2020-12-01 00:00:00

  • Age-related changes of the diffusion tensor imaging parameters of the normal cervical spinal cord.

    abstract:BACKGROUND:The diffusion tensor imaging (DTI) parameters of the cervical spinal cord (CSC) changes with age. However, previous studies only examined specific CSC areas. OBJECTIVES:To analyze the DTI parameters in all intervertebral space levels of the whole normal CSC and to study the impact of age on these parameters...

    journal_title:European journal of radiology

    pub_type: 杂志文章


    authors: Wang K,Song Q,Zhang F,Chen Z,Hou C,Tang Y,Chen S,Hao Q,Shen H

    更新日期:2014-12-01 00:00:00

  • Whole-body magnetic resonance angiography for presurgical planning of free-flap head and neck reconstruction.

    abstract:OBJECTIVES:Aim of the study was to evaluate if a whole-body magnetic resonance angiography (MRA) protocol meets the requirements to evaluate the donor and host site target vessels for planning of microvascular head and neck reconstructions. PATIENTS AND METHODS:In 20 patients, scheduled for reconstruction of the mandi...

    journal_title:European journal of radiology

    pub_type: 杂志文章


    authors: Kramer M,Nkenke E,Kikuchi K,Schwab SA,Janka R,Uder M,Lell M

    更新日期:2012-02-01 00:00:00

  • Effect of transarterial pulsed perfusion with heated saline on tumor vascular permeability in a rabbit VX2 liver tumor model.

    abstract:PURPOSE:To evaluate the effect of transarterial pulsed perfusion with 60 °C saline on vascular permeability of tumor tissue, as well as its hepatic and renal toxicity, in a rabbit VX2 liver model. MATERIALS AND METHODS:VX2 carcinomas were grown in rabbit livers, forty male New Zealand white tumor-bearing rabbits were ...

    journal_title:European journal of radiology

    pub_type: 杂志文章


    authors: Cao W,Li JH,Feng DY,Wan Y,Liu YF,Yang QF,Cheng JW,Zhao SY,Zhang HX

    更新日期:2012-03-01 00:00:00

  • The role of the radiologist in the management of politrauma patients.

    abstract::The management of trauma patients has become a very relevant issue and one of the major challenges in the western countries. In the assessment of politrauma patients, since the last 2 decades, radiological imaging methods have been increasingly used in order to provide a quick and thorough survey of craniocerebral, ce...

    journal_title:European journal of radiology

    pub_type: 杂志文章


    authors: Pinto F,Bode PJ,Tonerini M,Orsitto E

    更新日期:2006-09-01 00:00:00

  • High resolution magnetic resonance imaging of urethral anatomy in continent nulliparous pregnant women.

    abstract:INTRODUCTION:To quantify the distribution of morphologic appearances of urethral anatomy and measure variables of urethral sphincter anatomy in continent, nulliparous, pregnant women by high resolution magnetic resonance imaging (MRI). MATERIALS AND METHODS:We studied fifteen women during their first pregnancy. We def...

    journal_title:European journal of radiology

    pub_type: 杂志文章


    authors: Preyer O,Brugger PC,Laml T,Hanzal E,Prayer D,Umek W

    更新日期:2011-12-01 00:00:00

  • Impact of butylscopolamine on image quality of magnetic resonance cholangiopancreatography.

    abstract:PURPOSE:To assess the effect of parenteral butylscopolamine on magnetic resonance cholangiopancreatography (MRCP) image quality. MATERIALS AND METHODS:The 3D free-breathing respiratory-compensated MRCP images (mean acquisition time 7min) of 94 consecutive non-paired patients (47 with and 47 without 20mg intramuscular ...

    journal_title:European journal of radiology

    pub_type: 杂志文章


    authors: Venkatanarasimha N,Jenkins SJ,Yang N,Colak E,Kirpalani A

    更新日期:2013-04-01 00:00:00

  • Dual-modal computer-assisted evaluation of axillary lymph node metastasis in breast cancer patients on both real-time elastography and B-mode ultrasound.

    abstract:PURPOSE:To propose a computer-assisted method for quantifying the hardness of an axillary lymph node on real-time elastography (RTE) and its morphology on B-mode ultrasound; and to combine the dual-modal features for differentiation of metastatic and benign axillary lymph nodes in breast cancer patients. MATERIALS AND...

    journal_title:European journal of radiology

    pub_type: 杂志文章


    authors: Zhang Q,Suo J,Chang W,Shi J,Chen M

    更新日期:2017-10-01 00:00:00

  • PET/MRI of the breast.

    abstract::The future clinical use of the combination of positron emission tomography (PET) with 2-Fluoro[F-18]-2-Deoxy-d-Glucose (FDG)and MRI is still unclear. If a patient requires a PET and breast DCE-MRI for staging purposes, both scans can be done in the same visit. In the breast, DCE-MRI is better at lesion detection (sens...

    journal_title:European journal of radiology

    pub_type: 杂志文章,评审


    authors: Plecha DM,Faulhaber P

    更新日期:2017-09-01 00:00:00

  • Virtual non-enhanced dual-energy CT reconstruction may replace true non-enhanced CT scans in the setting of suspected active hemorrhage.

    abstract:OBJECTIVE:To assess virtual non-enhanced dual energy computed tomography (DECT) reconstruction as a potential alternative to true non-enhanced thoracic and abdominal CT scans in patients with suspected active hemorrhage. METHODS AND MATERIALS:Ninety-seven consecutive patients with suspected active bleeding, who underw...

    journal_title:European journal of radiology

    pub_type: 杂志文章


    authors: Walter SS,Schneeweiß S,Maurer M,Kraus MS,Wichmann JL,Bongers MN,Lescan M,Bamberg F,Othman AE

    更新日期:2018-12-01 00:00:00

  • Detection accuracy of in vitro approximal caries by cone beam computed tomography images.

    abstract:AIMS:To evaluate the diagnostic accuracy of approximal carious lesions among five CBCT systems and to assess the effect of detector types employed by different CBCT systems on the accuracy of approximal caries diagnosis. MATERIALS AND METHODS:Thirty-nine extracted non-cavitated human permanent teeth were employed in t...

    journal_title:European journal of radiology

    pub_type: 杂志文章


    authors: Qu X,Li G,Zhang Z,Ma X

    更新日期:2011-08-01 00:00:00

  • Combined pre-treatment MRI and 18F-FDG PET/CT parameters as prognostic biomarkers in patients with cervical cancer.

    abstract:OBJECTIVE:To determine the associations of quantitative parameters derived from multiphase contrast-enhanced magnetic resonance imaging (CE-MRI), diffusion-weighted (DW) MRI and 18F-fluorodeoxyglucose (18F-FDG) positron-emission tomography/computed tomography (PET/CT) with clinico-histopathological prognostic factors, ...

    journal_title:European journal of radiology

    pub_type: 杂志文章


    authors: Miccò M,Vargas HA,Burger IA,Kollmeier MA,Goldman DA,Park KJ,Abu-Rustum NR,Hricak H,Sala E

    更新日期:2014-07-01 00:00:00