Abstract:
PURPOSE:Quantification of tumour burden in oncology requires accurate and reproducible image evaluation. The current standard is one-dimensional measurement (e.g. RECIST) with inherent disadvantages. Volumetric analysis is discussed as an alternative for therapy monitoring of lung and liver metastases. The aim of this study was to investigate the accuracy of semi-automated volumetric analysis of artificial lymph node metastases in a phantom study. MATERIALS AND METHODS:Fifty artificial lymph nodes were produced in a size range from 10 to 55mm; some of them enhanced using iodine contrast media. All nodules were placed in an artificial chest phantom (artiCHEST®) within different surrounding tissues. MDCT was performed using different collimations (1-5 mm) at varying reconstruction kernels (B20f, B40f, B60f). Volume and RECIST measurements were performed using Oncology Software (Siemens Healthcare, Forchheim, Germany) and were compared to reference volume and diameter by calculating absolute percentage errors. RESULTS:The software performance allowed a robust volumetric analysis in a phantom setting. Unsatisfying segmentation results were frequently found for native nodules within surrounding muscle. The absolute percentage error (APE) for volumetric analysis varied between 0.01 and 225%. No significant differences were seen between different reconstruction kernels. The most unsatisfactory segmentation results occurred in higher slice thickness (4 and 5 mm). Contrast enhanced lymph nodes showed better segmentation results by trend. CONCLUSION:The semi-automated 3D-volumetric analysis software tool allows a reliable and convenient segmentation of artificial lymph nodes in a phantom setting. Lymph nodes adjacent to tissue of similar density cause segmentation problems. For volumetric analysis of lymph node metastases in clinical routine a slice thickness of ≤3mm and a medium soft reconstruction kernel (e.g. B40f for Siemens scan systems) may be a suitable compromise for semi-automated volumetric analysis.
journal_name
Eur J Radioljournal_title
European journal of radiologyauthors
Fabel M,Biederer J,Jochens A,Bornemann L,Soza G,Heller M,Bolte Hdoi
10.1016/j.ejrad.2010.10.019subject
Has Abstractpub_date
2011-12-01 00:00:00pages
e451-7issue
3eissn
0720-048Xissn
1872-7727pii
S0720-048X(10)00530-9journal_volume
80pub_type
杂志文章abstract:PURPOSE:To evaluate the accuracy of diffusion weighted MR imaging in diagnosis and quantification of hepatic fibrosis in children with chronic hepatitis. MATERIALS AND METHODS:Sixty-three consecutive children (40 boys, 23 girls, median age 9.3 years), with chronic hepatitis and thirty age matched volunteers underwent ...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2009.10.012
更新日期:2011-04-01 00:00:00
abstract:PURPOSE:To investigate associations between imaging features of tumors and age, gender and body mass index (BMI) in patients with renal cell carcinoma. METHOD:This IRB-approved, HIPAA-compliant study included 1348 patients with histopathologically confirmed renal cell carcinoma of the clear cell subtype (ccRCC, n = 90...
journal_title:European journal of radiology
pub_type: 杂志文章
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abstract:PURPOSE:The purpose of this study was to explore the nature of lesions in the pelvis and the long tubular bones that, with MR imaging, were found to contain both fat and fluid-like signal intensity and to correlate these findings with those of radiography, histologic analysis, and clinical and radiographic follow-up. ...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2004.02.008
更新日期:2005-01-01 00:00:00
abstract::This article provides an overview of the imaging findings of diseases affecting the optic nerve with special emphasis on clinical-radiological correlation and on the latest technical developments in MR imaging and CT. The review deals with congenital malformations, tumors, toxic/nutritional and degenerative entities, ...
journal_title:European journal of radiology
pub_type: 杂志文章,评审
doi:10.1016/j.ejrad.2009.09.029
更新日期:2010-05-01 00:00:00
abstract:PURPOSE:Primary extranodal lymphomas of the orbit and sinonasal region are rare and occur almost only as Non-Hodgkin lymphoma (NHL). The purpose of this study was to determine the frequency of different subtypes of NHL in these regions and to describe their radiological features. MATERIALS AND METHODS:Between January ...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2012.03.036
更新日期:2013-02-01 00:00:00
abstract::Screening (early detection of disease in asymptomatic groups of persons) with whole-body MR (wb-MR) has only recently become possible. Technical requirements include extended scanner table range and extended coverage with surface coils. This allows for examining the whole body without repositioning the patient. wb-MR ...
journal_title:European journal of radiology
pub_type: 杂志文章,评审
doi:10.1016/j.ejrad.2009.02.011
更新日期:2009-06-01 00:00:00
abstract:PURPOSE:To evaluate the radiologic and clinicopathologic factors in radiologic-pathologic discordance (false-negative results) in breast cancer patients who demonstrate radiologic complete response (rCR) in MR imaging after neoadjuvant chemotherapy (NAC). METHOD:Our institutional review board approved this retrospecti...
journal_title:European journal of radiology
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abstract::Two principally different 1000-line CRT (cathode ray tube) monitors connected to a digital image intensifier system for chest radiography were compared in terms of image quality and viewing comfort. Image quality was assessed by means of ROC analysis. Five observers tried to find simulated pathology positioned over th...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/0720-048x(96)00750-4
更新日期:1996-06-01 00:00:00
abstract::We report a case of giant, benign renal cyst that was treated with percutaneous aspiration and sclerotherapy using 95% alcohol. A seven French catheter was inserted into the cyst under ultrasonographic and fluoroscopic guidance, and was then left in place to drain the cyst contents. Approximately 4 l of fluid was drai...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/s0720-048x(01)00280-7
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abstract:PURPOSE:The clinical adoption of quantitative imaging biomarkers (radiomics) has established the need for high quality contrast-enhancement in medical images. We aimed to develop a machine-learning algorithm for Quality Control of Contrast-Enhancement on CT-scan (CECT-QC). METHOD:Multicenter data from four independent...
journal_title:European journal of radiology
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abstract:PURPOSE:To investigate the potential of ESWAN in differentiating borderline epithelial ovarian tumors (BEOTs) from malignant epithelial ovarian tumors (MEOTs). METHOD:Thirty-four patients with 37 lesions were enrolled, including 14 BEOTs and 23 MEOTs. The magnitude, phase, R2* and T2* maps were analyzed by two observe...
journal_title:European journal of radiology
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doi:10.1016/j.ejrad.2019.07.011
更新日期:2019-09-01 00:00:00
abstract::Our patient presented with a typical case history and typical symptoms. She also belongs to a group with a high incidence of the disorder. The diagnosis was suspected at ultrasonography, which accurately detected the presence and location of a cyst, but could not establish its origin. Computed tomography is a better d...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/0720-048x(90)90128-x
更新日期:1990-03-01 00:00:00
abstract:PURPOSE:Lung perfusion analysis at dual energy CT (DECT) is sensitive to beam hardening artifacts from dense contrast material (CM). We compared two scan and four CM injection protocols in terms of severity of artifacts and attenuation levels in the thoracic vessels. METHODS AND MATERIALS:Data of 120 patients who had ...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2010.09.030
更新日期:2011-12-01 00:00:00
abstract:BACKGROUND:Dynamic contrast enhanced (DCE) MRI parameters are potential biomarkers to characterise tumour vasculature and distinguish it from the non-cancerous blood vessel system within the prostate. However, the inevitable presence of intra- and inter-observer variabilities is challenging in this context. Additionall...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2019.04.015
更新日期:2019-07-01 00:00:00
abstract::Contrast-enhanced sonography is a widely available imaging modality for the diagnosis of pancreatic diseases. With this procedure, pancreatic tumours can be differentiated better. Furthermore, contrast-enhanced sonography produces good results in the staging of acute pancreatitis severity, especially in the detection ...
journal_title:European journal of radiology
pub_type: 杂志文章,评审
doi:10.1016/j.ejrad.2007.06.035
更新日期:2007-11-01 00:00:00
abstract:PURPOSE:CT artifacts from port-systems are a common problem in staging- and restaging-examinations and reduce image quality and diagnostic assessment. The purpose of this study was to investigate the reduction of these artifacts using virtual monoenergetic images (VMI) from dual-energy spectral-detector CT (SDCT) in co...
journal_title:European journal of radiology
pub_type: 杂志文章,评审
doi:10.1016/j.ejrad.2019.108733
更新日期:2019-12-01 00:00:00
abstract::Diabetic mastopathy is a recently described collection of radiographical and histological features found in dense fibrous masses of the breast in long standing Type I diabetes. We describe the first case of bilateral disease with the alternate progression and regression of the disease over a 5 year period. A 45-year-o...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/s0720-048x(97)00029-6
更新日期:1998-02-01 00:00:00
abstract:PURPOSE:Regurgitant fraction (RF) measured from 2D phase-contrast MRI has been used as a standard to quantitate the degree of pulmonary regurgitation and serves as a determinant indicator of prognosis for tetralogy of Fallot after surgical repair. This study demonstrated the potential underestimate of RF using the conv...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2017.05.027
更新日期:2017-08-01 00:00:00
abstract:PURPOSE:To investigate the diagnostic value of retrospective fusion of pelvic MRI and (18)F-fluorodeoxyglucose ((18)F-FDG) PET images for assessment of locoregional extension and nodal staging of endometrial cancer. MATERIALS AND METHODS:Thirty patients with biopsy-proven endometrial cancer underwent preoperative cont...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2013.05.005
更新日期:2013-10-01 00:00:00
abstract::In the present study ultrasonography observed the tail of the pancreas more frequently through the spleen than by any other approach. If the splenic approach fails, examination through the fluid-filled stomach may be tried. ...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:
更新日期:1986-05-01 00:00:00
abstract::The purpose of this study is to clarify the prevalence, spectrum of associated tumors and the diagnostic value of the linear meningeal thickening and enhancement adjacent to a peripherally located cranial mass "dural tail sign"(DTS) in contrast enhanced magnetic resonance imaging (MRI). In this prospective descriptive...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2006.04.003
更新日期:2006-10-01 00:00:00
abstract:OBJECTIVES:To investigate the acute and repeated pulmonary damage in Sprague-Dawley rats caused by the inhalation of 3-methoxybutyl chloroformate (3-MBCF) using computed tomography (CT), and to correlate these results with those obtained from a pathological study. METHODS:Sixty, 7-week-old rats were exposed to 3-MBCF ...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2006.11.035
更新日期:2007-05-01 00:00:00
abstract::The management of trauma patients has become a very relevant issue and one of the major challenges in the western countries. In the assessment of politrauma patients, since the last 2 decades, radiological imaging methods have been increasingly used in order to provide a quick and thorough survey of craniocerebral, ce...
journal_title:European journal of radiology
pub_type: 杂志文章
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更新日期:2006-09-01 00:00:00
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journal_title:European journal of radiology
pub_type: 杂志文章,meta分析,多中心研究
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更新日期:2019-07-01 00:00:00
abstract:OBJECTIVE:To compare two different expandable electrodes in radiofrequency ablation of renal cell carcinoma. METHODS:Percutaneous ablation was performed at two centers using either an expandable 7F umbrella-shaped LeVeen probe (diameter 2-4 cm) and a 200-W generator (group A), or an expandable Starburst XL electrode w...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2006.04.005
更新日期:2006-08-01 00:00:00
abstract::The goal of this study was to explore possible specific mammographic and sonographic features in women with non-puerperal mastitis (NPM), in order to make an accurate diagnosis and prevent unnecessary surgical procedures. From a group of 93 patients with NPM diagnosed between 1987 and 1992, the mammograms of 41, the s...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/0720-048x(95)00699-q
更新日期:1995-12-15 00:00:00
abstract::Statins are widely used to lower increased cholesterol levels with the aim to prevent major cardiovascular events. However, they bare the risk of myotoxic side effects. We report on two patients with focal weakness and pain in the upper extremities. In both patients, abnormal MRI signal heights in the muscle groups in...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2010.12.031
更新日期:2011-02-01 00:00:00
abstract::Functional magnetic resonance imaging (fMRI) is poised to make significant contributions to the study of neuropsychiatric illnesses. Whatever neural pathology attends such illnesses has proven subtle at best. By identifying predictable, regionally specific deficits in brain function, fMRI can suggest brain regions for...
journal_title:European journal of radiology
pub_type: 杂志文章,评审
doi:10.1016/s0720-048x(99)00048-0
更新日期:1999-05-01 00:00:00
abstract::In vivo generated positron emitting radioisotopes, primarily C-11 and N-13, have been documented following therapy with accelerators larger than 10 MeV. Six patients had positron emission tomography 15 to 25 minutes after radiation therapy with a 42 MeV accelerator. Five patients had recurrent colorectal malignancy, a...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:
更新日期:1989-11-01 00:00:00
abstract:PURPOSE:To evaluate whether pancreatic magnetic resonance imaging-proton density fat fraction (MRI-PDFF) correlates with histological pancreatic fat fraction and its possible usefulness as a biomarker of pancreatic cancer compared with pancreatic index (PI) using computed tomography (CT number of the pancreas divided b...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2019.06.024
更新日期:2019-09-01 00:00:00