Abstract:
:Functional magnetic resonance imaging (fMRI) is poised to make significant contributions to the study of neuropsychiatric illnesses. Whatever neural pathology attends such illnesses has proven subtle at best. By identifying predictable, regionally specific deficits in brain function, fMRI can suggest brain regions for detailed cellular analyses, provide valuable in vivo data regarding effective connectivity, provide a means to model the effects of various drug challenge paradigms, and characterize intermediate phenotypes in the search for the genes underlying mental illness. Nonetheless, as promising as fMRI appears to be in terms of its relative safety, repeatability, ability to generate individual brain maps and widespread availability, it is still subject to a number of unresolved conceptual conundrums inherited from earlier neuroimaging work. For example, functional neuroimaging has not generated any pathognomic findings in mental illness, has not established a clear link between neurophysiology and observable behavior, and has not resolved the potential confounds of medication. In this article, we will review the relevant historical background preceding fMRI, address methodological considerations in fMRI, and summarize recent fMRI findings in psychiatry. Finally, fMRI is being used to simplify the complex genetics of neuropsychiatric illness by generating quantitative and qualitative brain phenotypes.
journal_name
Eur J Radioljournal_title
European journal of radiologyauthors
Callicott JH,Weinberger DRdoi
10.1016/s0720-048x(99)00048-0keywords:
subject
Has Abstractpub_date
1999-05-01 00:00:00pages
95-104issue
2eissn
0720-048Xissn
1872-7727pii
S0720-048X(99)00048-0journal_volume
30pub_type
杂志文章,评审abstract:PURPOSE:To compare the diagnostic performances of digital breast tomosynthesis (DBT) and ultrasound for the dense breasts with category 0 at conventional digital mammography. MATERIALS AND METHODS:This retrospective study was approved by the institutional review board, and informed consent was waived. Among the 1103 p...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2015.09.026
更新日期:2016-01-01 00:00:00
abstract:AIM:The aim of the study is to present the feasibility of using dual-energy CT and the evaluation of iodine and air distribution in differentiation of pathological conditions. MATERIAL AND METHOD:We used the data of 50 CT examinations performed due to suspected pulmonary embolism with any pathological finding except c...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2009.08.005
更新日期:2011-02-01 00:00:00
abstract::The purpose of this study was to investigate whether dynamic contrast enhanced MRI (DCE-MRI) data, both pharmacokinetic and empirical, can predict, prior to neoadjuvant chemotherapy, which patients are likely to have a shorter disease free survival (DFS) and overall survival (OS) interval following surgery. Traditiona...
journal_title:European journal of radiology
pub_type: 临床试验,杂志文章
doi:10.1016/j.ejrad.2008.05.007
更新日期:2009-09-01 00:00:00
abstract:PURPOSE:Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a treatable, immune-mediated condition characterised by progressive or relapsing motor and sensory neurological deficits. The diagnosis is based on a combination of clinical, neurophysiological and supportive criteria, but can be challenging. I...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2020.109164
更新日期:2020-09-01 00:00:00
abstract::From April 1992 to January 1993, radiology expert opinion for MRI procedures was offered by means of teleradiology. The experiment was carried out in addition to an existing service of a mobile MRI unit. MRI images were sent by means of teleradiology via regular telephone lines from the mobile MRI unit to an academic ...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/0720-048x(94)00573-u
更新日期:1995-01-01 00:00:00
abstract:PURPOSE:To compare lesion conspicuity and image quality between single-shot spin echo echo planar imaging (SS SE-EPI) before, immediately and 5min after intravenous (IV) injection of superparamagnetic iron oxide (SPIO) for detecting and characterizing focal liver lesions (FLLs). MATERIALS AND METHODS:Twenty-five patie...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2008.09.005
更新日期:2009-12-01 00:00:00
abstract:PURPOSE:To evaluate prospectively the value of size, shape, margin and density in discriminating between benign and malignant CT screen detected solid non-calcified pulmonary nodules. MATERIAL AND METHODS:This study was institutional review board approved. For this study 405 participants of the NELSON lung cancer scre...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2007.08.027
更新日期:2008-11-01 00:00:00
abstract::MR imaging directly shows integrity of spinal cord, and provides sensitive assessments of structurally important soft tissue investments of the vertebral column. High-resolution images should be acquired in at least two planes, with T1 and fluid sensitive sequences. In the acute and subacute settings, MR may be used t...
journal_title:European journal of radiology
pub_type: 杂志文章,评审
doi:10.1016/s0720-048x(03)00201-8
更新日期:2003-10-01 00:00:00
abstract:INTRODUCTION:Cerebral CT angiography (CTA) is an established method applied to both the detection and treatment planning of intracranial aneurysms. The aim of our study was to compare CTA and digital subtraction angiography (DSA) findings with the surgical results mainly in patients with acute SAH and to evaluate the c...
journal_title:European journal of radiology
pub_type: 临床试验,杂志文章
doi:10.1016/S0720-048X(03)00173-6
更新日期:2004-03-01 00:00:00
abstract:PURPOSE:This study aimed to compare the quality of abdominal CT angiography (CTA) images obtained using conventional reconstruction algorithms with those obtained using a novel iterative algorithm (forward projected model-based iterative reconstruction solution, FIRST) for evaluating arteries in the abdomen. MATERIALS...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2018.07.015
更新日期:2018-09-01 00:00:00
abstract:PURPOSE:The aim of this study was to evaluate the impact of a patient-tailored contrast volume protocol on portal venous phase abdominal CT-images compared to a fixed volume protocol in daily radiological practice. METHOD:Data of 77 patients who underwent two contrast-enhanced CT-examinations were collected. The first...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2019.07.031
更新日期:2019-12-01 00:00:00
abstract:PURPOSE:To examine factors associated with one step surgery in case of non-palpable breast cancer. MATERIALS AND METHODS:Clinical data of 152 consecutively diagnosed patients with breast cancer were analyzed retrospectively. Preoperative diagnostic findings were divided in subgroups: mammographically visible mass/micr...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2007.02.033
更新日期:2007-12-01 00:00:00
abstract::Statins are widely used to lower increased cholesterol levels with the aim to prevent major cardiovascular events. However, they bare the risk of myotoxic side effects. We report on two patients with focal weakness and pain in the upper extremities. In both patients, abnormal MRI signal heights in the muscle groups in...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2010.12.031
更新日期:2011-02-01 00:00:00
abstract:OBJECTIVES:We investigated the role of novel intra-abdominal parameters measured by computed tomography (CT) in the prediction of clinical outcomes in acute pancreatitis (AP). METHODS:Patients with AP underwent an abdominal CT scan on admission to define different intra-abdominal parameters (abdominal circumference, p...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2020.109327
更新日期:2020-11-01 00:00:00
abstract:OBJECTIVE:The Breast Lesion Excision System (BLES) is a novel, automatic breast biopsy device that utilizes radiofrequency to excise suspicious non-palpable mammographic lesions. The purpose of the present prospective study is to report and evaluate the complications of this new technique. MATERIALS AND METHODS:In a t...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2011.12.023
更新日期:2013-04-01 00:00:00
abstract:OBJECTIVE:To prospectively compare test bolus and bolus tracking for the determination of scan delay of pulmonary dual-energy CT angiography in patients with suspected pulmonary embolism. MATERIALS AND METHODS:60 consecutive patients referred for CTA for exclusion of PE were randomized either into a test bolus group o...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2010.06.023
更新日期:2012-01-01 00:00:00
abstract:PURPOSE:Objective quantification of brain structure can aid diagnosis and therapeutic monitoring in several neuropsychiatric disorders. In this study, we aimed to compare direct and indirect quantification approaches for hippocampal formation changes in patients with mild cognitive impairment and Alzheimer's disease (A...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2007.06.009
更新日期:2008-05-01 00:00:00
abstract:OBJECTIVE:To evaluate the magnetic resonance imaging (MRI) findings of 15 patients with perineural tumor extension along the trigeminal nerve in correlation with clinical data. METHODS:The clinical records and MRI studies of 15 patients with perineural tumor extension along the trigeminal nerve were retrospectively re...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/s0720-048x(96)01122-9
更新日期:1997-05-01 00:00:00
abstract:PURPOSE:The aim of this investigation is to establish the relationship between the size-dependent conversion factor (fsize) and the body-mass-index (BMI) and to test whether BMI can be substituted for the conventionally used patients' anterior-posterior (AP) and lateral (LAT) dimensions for calculation of fsize. By cal...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2018.01.027
更新日期:2018-03-01 00:00:00
abstract::Light food diet and low residual diet with hydration, both combined with Proctosal and Bisacodyl cleansing, were compared in 268 patients in the preparation of the colon for double contrast examination. Low residual diet with hydration resulted in significantly less residual fecal material, no flocculation of the bari...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:
更新日期:1983-08-01 00:00:00
abstract:PURPOSE:The most common pituitary tumors are adenomas, which however may be mimicked by other tumors that can show a very similar appearance in plain MRI. The aim of our study was to evaluate the usefulness of perfusion weighted MR imaging (PWI), including signal-intensity curves analysis in the differential diagnosis ...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2013.01.033
更新日期:2013-08-01 00:00:00
abstract:OBJECTIVE:To assess virtual non-enhanced dual energy computed tomography (DECT) reconstruction as a potential alternative to true non-enhanced thoracic and abdominal CT scans in patients with suspected active hemorrhage. METHODS AND MATERIALS:Ninety-seven consecutive patients with suspected active bleeding, who underw...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2018.10.026
更新日期:2018-12-01 00:00:00
abstract:PURPOSE:This study assesses the rate of enhancement of breast fibroglandular tissue after administration of a magnetic resonance imaging (MRI) gadolinium-based contrast agent and determines its relationship with response to neoadjuvant therapy (NAT) in women with breast cancer. METHOD:Women with locally advanced breas...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2021.109534
更新日期:2021-01-09 00:00:00
abstract:PURPOSE:Previous studies have established regional grey matter (GM) loss in multiple sclerosis (MS). However, whether there is any regional GM atrophy in neuromyelitis optica (NMO) and the difference between NMO and MS is unclear. The present study addresses this issue by voxel-based morphometry (VBM). METHODS:Convent...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2011.01.065
更新日期:2012-02-01 00:00:00
abstract::A 28-year-old woman with primarily therapy refractory TTP was followed neuroradiologically over 6 months. Despite pronounced neurological and neuropsychiatric symptoms including hemiparesis and aphasia she had unremarkable CT scans on two occasions. Three MRI exams showed no correlate for her neurological symptoms exc...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/s0720-048x(98)00088-6
更新日期:1999-07-01 00:00:00
abstract:PURPOSE:To compare the measurement variability for coronary artery calcium (CAC) measurements using mineral mass compared with a modified Agatston score (AS) or volume score (VS) with multi-detector CT (MDCT) scanning, and to estimate the potential impact of these methods on the design of CAC progression studies. MATE...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2005.12.027
更新日期:2006-03-01 00:00:00
abstract:PURPOSE:"Misty mesentery" is a CT appearance of mesenteric fat changes with increased attenuation often existing with swelled mesenteric lymph nodes. We evaluated diagnostic performance of FDG-PET/CT in distinguishing viable malignant disorders from benign conditions in misty mesentery. MATERIALS AND METHODS:4236 FDG-...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2013.03.016
更新日期:2013-08-01 00:00:00
abstract:PURPOSE:Human metapneumovirus has been increasingly identified as a cause of lower respiratory tract infection in adults worldwide. The CT imaging features of human metapneumovirus in adults have not been characterized. The purpose of this paper is to determine the imaging features of human metapneumovirus and to compa...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2020.108988
更新日期:2020-07-01 00:00:00
abstract:PURPOSE:We aimed to identify and assess cardiac abnormalities by cardiovascular magnetic resonance (CMR) in a non-ischaemic aborted sudden cardiac death (SCD) population and to establish possible predictors of SCD. METHODS:Thirty-six consecutive SCD survivors [median age 37.6 years (IQR 24.1-43.2), 31% female] with no...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2018.06.004
更新日期:2018-08-01 00:00:00
abstract::The value of CT in the staging and assessment of resectability is demonstrated in 40 patients with advanced gastric carcinoma. The accuracy of CT using the pTNM classification of gastric carcinoma was 90% in the T category, 52.5% in the N category, 80% in the M category, and 72.5% as regards the correct staging. CT es...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:
更新日期:1986-08-01 00:00:00