Abstract:
OBJECTIVES:To investigate the acute and repeated pulmonary damage in Sprague-Dawley rats caused by the inhalation of 3-methoxybutyl chloroformate (3-MBCF) using computed tomography (CT), and to correlate these results with those obtained from a pathological study. METHODS:Sixty, 7-week-old rats were exposed to 3-MBCF vapor via inhalation (6 h/day) for 1 day (N=20), 3 days (N=20), and 28 days (5 days/week) (N=20) using whole body exposure chambers at a concentration of 0 (control), 3, 6 and 12 ppm. CT examinations including densitometry and histopathologic studies were carried out. For the follow-up study, the rats exposed for 3 days were scanned using CT and their pathology was examined at 7, 14, and 28 days. RESULTS:There was a significant decrease in the parenchymal density in the groups exposed to the 3-MBCF vapors for 1 day at 3 ppm (p=0.022) or 6 ppm (p=0.010), compared with the control. The parenchymal density of the rats exposed to 12 ppm was significantly higher. The pathological findings in this period, the grades of vascular congestion, tracheobronchial exfoliation, and alveolar rupture were significant. In the groups exposed for 3 days, there was a large decrease in the parenchymal density with increasing dose (control: -675.48+/-32.82 HU, 3 ppm: -720.65+/-34.21 HU, 6 ppm: -756.41+/-41.68 HU, 12 ppm: -812.56+/-53.48 HU) (p=0.000). There were significant density differences between each dose in the groups exposed for 28 days (p=0.000). The CT findings include an irregular lung surface, areas of multifocal, wedge-shaped increased density, a heterogeneous lung density, bronchial dilatation, and axial peribronchovascular bundle thickening. The histopathology examination revealed the development of alveolar interstitial thickening and vasculitis, and an aggravation of the mainstem bronchial exudates and bronchial inflammation. The alveolar wall ruptures and bronchial dilatation became severe during this period. On the follow-up study, the groups exposed for 3 days showed diffusely increased parenchymal density on the 7 days study, but the lung densities were lower at 14 and 28 days than at 3 days. In the rats exposed to lowest concentration, the pulmonary parenchymal density and pathologic findings rapidly returned to normal within 1 week. CONCLUSIONS:Decreased parenchymal density of the lung was a common CT finding in acute and repeated inhalation injury. The air accumulation is believed to be the results of tracheolaryngeal inflammatory edema, bronchial dilatation, and alveolar rupture from the early period.
journal_name
Eur J Radioljournal_title
European journal of radiologyauthors
Lim YS,Chung MH,Park SH,Kim HY,Choi BG,Lim HW,Kim JA,Yoo WJdoi
10.1016/j.ejrad.2006.11.035subject
Has Abstractpub_date
2007-05-01 00:00:00pages
227-34issue
2eissn
0720-048Xissn
1872-7727pii
S0720-048X(06)00523-7journal_volume
62pub_type
杂志文章abstract:OBJECTIVES:Breast cancer is the second cause of death in women in Europe and North America. The mortality of this disease can be reduced with effective therapy and regular follow up to detect early recurrence. Tumor markers are sensitive in detecting recurrent or residual disease but imaging is required to customize th...
journal_title:European journal of radiology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ejrad.2010.04.029
更新日期:2011-12-01 00:00:00
abstract::We report a case of giant, benign renal cyst that was treated with percutaneous aspiration and sclerotherapy using 95% alcohol. A seven French catheter was inserted into the cyst under ultrasonographic and fluoroscopic guidance, and was then left in place to drain the cyst contents. Approximately 4 l of fluid was drai...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/s0720-048x(01)00280-7
更新日期:2001-10-01 00:00:00
abstract:OBJECTIVE:To compare outcomes after imaging-guided transforaminal lumbar nerve root blocks in MRI confirmed symptomatic disc herniation patients with and without Modic changes (MC). METHODS:Consecutive adult patients with MRI confirmed symptomatic lumbar disc herniations and an imaging-guided lumbar nerve root block i...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2014.06.008
更新日期:2014-10-01 00:00:00
abstract:OBJECTIVES:The aim of this systematic review was to compare the diagnostic accuracy, subjective image quality and clinical consequences of 3D-fluoroscopy with standard imaging modalities (2D-fluoroscopy, X-ray or CT) during reduction and fixation of intra-articular upper and lower extremity fractures. METHODS:A system...
journal_title:European journal of radiology
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.ejrad.2012.06.021
更新日期:2012-12-01 00:00:00
abstract::Our purpose is to clarify the diffusion-weighted (DW) imaging findings of adnexal torsion. We retrospectively analyzed the DW imaging findings in 11 consecutive patients with surgical confirmation of adnexal torsion. We assessed signal intensity of the adnexal mass and fallopian tube thickening, and the location of ab...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2009.07.040
更新日期:2011-02-01 00:00:00
abstract:INTRODUCTION:Spontaneous pneumothorax (SP) is a frequent complication in non-treated HIV-infected patients as a complication of opportunistic infections and tumours. OBJECTIVE:To analyse the aetiology of SP in non-treated HIV patients. PATIENTS AND METHODS:Observational study of SP cases observed in a cohort of 9831 ...
journal_title:European journal of radiology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ejrad.2008.05.003
更新日期:2009-08-01 00:00:00
abstract:OBJECTIVE:We hypothesized that Displacement Encoding with Stimulated Echoes (DENSE) and feature-tracking derived circumferential strain would provide incremental prognostic value over the extent of infarction for recovery of segmental myocardial function. METHODS:Two hundred and sixty-one patients (mean age 59 years, ...
journal_title:European journal of radiology
pub_type: 临床试验,杂志文章
doi:10.1016/j.ejrad.2019.01.010
更新日期:2019-03-01 00:00:00
abstract::Femoroacetabular impingement is a relatively recently appreciated "idiopathic" cause of hip pain and degenerative change. Two types of impingement have been described. The first, cam impingement, is the result of an abnormal morphology of the proximal femur, typically at the femoral head-neck junction. Cam impingement...
journal_title:European journal of radiology
pub_type: 杂志文章,评审
doi:10.1016/j.ejrad.2007.03.020
更新日期:2007-07-01 00:00:00
abstract::This paper discusses ten patients who developed acute cholecystitis during the postoperative period following surgery which did not involve the gall bladder. All were examined with ultrasound during the first two weeks after surgery and were diagnosed as acute cholecystitis. Six (60%) had complications such as empyema...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:
更新日期:1985-02-01 00:00:00
abstract:OBJECTIVE:Although whole-body fluorine-18 fluorodeoxyglucose (18F-FDG) positron emission tomography (PET)/computed tomography (CT) (18F-FDG PET/CT) is commonly used for M staging of newly diagnosed nasopharyngeal carcinoma (NPC), some patients may not benefit from this procedure. The present study investigated which pa...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2017.02.002
更新日期:2017-04-01 00:00:00
abstract:OBJECTIVE:To assess the effect of breast density, fibroglandular tissue volume, and breast volume on the rate of false-positive marks of a computer-assisted detection software in digital mammography. MATERIALS AND METHODS:222 patients with normal digital mammograms and a minimum follow-up of 22 months were retrospecti...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2012.02.017
更新日期:2012-08-01 00:00:00
abstract::The aim of this study was to assess the feasibility of a new MR-pathologic correlation method utilizing a high-resolution MR technique with a 3-inch surface coil and elimination of susceptibility by replacing air in the pulmonary alveoli of lung specimens with water. Inflated cadaver lung specimens of various lung dis...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/s0720-048x(02)00270-x
更新日期:2002-12-01 00:00:00
abstract::This is a retrospective study of a series of seven patients with pancreatic metastases studied by ultrasonography and computed tomography. They were detected during tumor staging, or in the follow-up period of over 10 years of patients with advanced known malignancy. Lesions were multiple in two patients and solitary ...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/0720-048x(91)90131-e
更新日期:1991-01-01 00:00:00
abstract::The pulmonary radiological manifestations of lipoid pneumonia following a cultural practice of forced feeding of rendered animal fat (ghee) in 24 Saudi children are described. The age range is 15 days to 11 years with 68% of cases being in infancy. The chest radiographic appearances encountered could be grouped into f...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/0720-048x(93)90077-z
更新日期:1993-04-01 00:00:00
abstract:OBJECTIVES:To examine the efficacy of qualitative shear wave elastography (SWE) in the classification and evaluation of solid breast masses, and to compare this method with conventional ultrasonograghy (US), quantitative SWE parameters and qualitative SWE classification proposed before. METHODS:From April 2015 to Marc...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2016.12.021
更新日期:2017-02-01 00:00:00
abstract:OBJECTIVES:To assess the most optimal multi-parametric magnetic resonance imaging sequence (Mp-MRI) in determining pathological length of capsular contact (LCC) for the diagnosis of prostate cancer extraprostatic extension (EPE). METHODS:105 patients with prostate cancer who underwent Mp-MRI of prostate prior to radic...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2019.01.020
更新日期:2019-03-01 00:00:00
abstract::Post-operative paediatric cerebellar mutism syndrome (pCMS) occurs in around 25% of children undergoing surgery for cerebellar and fourth ventricular tumours. Reversible mutism is the hallmark of a syndrome which comprises severe motor, cognitive and linguistic deficits. Recent evidence from advanced neuroimaging stud...
journal_title:European journal of radiology
pub_type: 杂志文章,评审
doi:10.1016/j.ejrad.2018.09.007
更新日期:2018-11-01 00:00:00
abstract:UNLABELLED:The purpose of this study was to investigate the potential correlation between the presence and size of the cisterna chyli (CC) on computed tomography (CT) and the presence of cardiovascular disease. MATERIALS AND METHODS:Out of a 3000-patient cohort 2599 patients who received a CT examination of the chest ...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2010.02.009
更新日期:2011-08-01 00:00:00
abstract::Tuberous sclerosis is an uncommon heredito-familial disease. A rare case of multiple organ involvement is reported. ...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/s0720-048x(96)01074-1
更新日期:1997-07-01 00:00:00
abstract:OBJECTIVE:To evaluated the efficacy and safety of radiofrequency ablation (RFA) with intraperitoneal saline infusion. BACKGROUND:Ultrasound-guided RFA is not always feasible due to the tumor location, possible adjacent tissue damage or poor sonographic identification. PATIENTS AND METHODS:Ultrasound-guided RFA with i...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2009.03.037
更新日期:2010-06-01 00:00:00
abstract:PURPOSE:Thin-section CT is the modality of choice for morphological imaging the lung parenchyma, while proton-MRI might be used for functional assessment. However, the capability of MRI to visualize morphological parenchymal alterations in emphysema is undetermined. Thus, the aim of the study was to compare different M...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2008.09.029
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:The management of community-acquired pneumonia (CAP) depends, in part, on the identification of the causative agents. The objective of this study was to determine the potential of thin-section computed tomography (CT) in differentiating bacterial and non-bacterial pneumonia. PATIENTS AND METHO...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2008.08.004
更新日期:2009-12-01 00:00:00
abstract::Today US plays an important and increasing role in the assessment of many, partially age-specific conditions in the GI tract in neonates, infants and children. Knowledge of the potential capabilities of US and its restrictions together with a skillful performance of GI US examination can provide essential anatomic and...
journal_title:European journal of radiology
pub_type: 杂志文章,评审
doi:10.1016/j.ejrad.2014.04.016
更新日期:2014-09-01 00:00:00
abstract::This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy. ...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2010.12.015
更新日期:2011-01-26 00:00:00
abstract::In this overview the results and indications of Magnetic Resonance Angiography of the intracranial vasculature will be discussed. The value of MRA will be studied in the visualisation of normal variants of the cerebral anatomy, the imaging of cerebrovascular disease, the diagnosis of aneurysms and cerebral arterioveno...
journal_title:European journal of radiology
pub_type: 杂志文章,评审
doi:10.1016/s0720-048x(01)00285-6
更新日期:2001-04-01 00:00:00
abstract::Teleradiology is probably the most successful eHealth service available today. Its business model is based on the remote transmission of radiological images (e.g. X-ray and CT-images) over electronic networks, and on the interpretation of the transmitted images for diagnostic purpose. Two basic service models are comm...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2009.10.018
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Incidentally discovered adrenal masses are commonly seen with high resolution diagnostic imaging performed for indications other than adrenal disease. Although the majority of these masses are benign and non-secretory, their unexpected discovery prompts further biochemical and often repeated imag...
journal_title:European journal of radiology
pub_type: 杂志文章,评审
doi:10.1016/j.ejrad.2010.12.060
更新日期:2012-03-01 00:00:00
abstract:PURPOSE:To identify differences in the radiological findings of invasive pulmonary aspergillosis (IPA) among patients classified by severity of neutropenia, and differences in underlying disease. MATERIALS AND METHODS:We retrospectively reviewed computed tomography (CT) scans from the time of the diagnosis of IPA in 8...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2020.109042
更新日期:2020-10-01 00:00:00
abstract::A 73-year-old woman with a large esophagorespiratory fistula underwent bronchoscopy and computed tomographic (CT) virtual endoscopy before stenting. Noninvasive CT virtual endoscopy showed the large fistula, and the CT findings agreed with the bronchoscopic findings. ...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/s0720-048x(99)00100-x
更新日期:2000-04-01 00:00:00
abstract::Two principally different 1000-line CRT (cathode ray tube) monitors connected to a digital image intensifier system for chest radiography were compared in terms of image quality and viewing comfort. Image quality was assessed by means of ROC analysis. Five observers tried to find simulated pathology positioned over th...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/0720-048x(96)00750-4
更新日期:1996-06-01 00:00:00