Abstract:
AIM:To ensure optimal timing with pre-operative spiral CT for abdominal aortic aneurysms (AAA), an initial 'timing' single level CT is commonly performed with a small bolus of contrast. This can be exploited to obtain adjunct functional information on renal perfusion. We have investigated the potential of this to measure renal perfusion, to produce colour renal perfusion maps and to predict surgical outcome in infrarenal aortic aneurysm assessment. METHODS:We studied 21 patients being assessed for repair of infrarenal AAA. Prior to the spiral CT, a single level through the renal hili and aorta was scanned after the intravenous injection of 25 ml of contrast given at 10 ml/s. Ten 1 s duration scans were performed from 8 to 30 s after injection. Optimal timing for CT angiography can then be determined. Time-density curves were then drawn for both kidneys and aorta using regions of interest (ROIs) or pixel-by-pixel analysis. Renal cortical perfusion was measured using both ROI analysis and pseudocolour perfusion images. Following previous work, perfusion was calculated as the peak upslope of the tissue time density curve divided by peak aortic enhancement. RESULTS:Cortical mean perfusion averaged 2.48 ml/min per ml (range 0.8-3.7 ml/min per ml n = 34) and the values obtained agreed with literature expectations. Follow up in the 10 patients proceeding to AAA repair suggest low mean perfusion values and predict a raised postoperative creatinine (P < 0.05) CONCLUSIONS:Additional functional data and imaging can be obtained from the initial timing scan of a CT study, without requiring a dedicated study.
journal_name
Eur J Radioljournal_title
European journal of radiologyauthors
Blomley MJ,McBride A,Mohammedtagi S,Albrecht T,Harvey CJ,Jäger R,Standfield NJ,Dawson Pdoi
10.1016/s0720-048x(99)00014-5keywords:
subject
Has Abstractpub_date
1999-06-01 00:00:00pages
214-20issue
3eissn
0720-048Xissn
1872-7727pii
S0720048X99000145journal_volume
30pub_type
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