Abstract：
OBJECTIVE:To determine the associations of quantitative parameters derived from multiphase contrast-enhanced magnetic resonance imaging (CE-MRI), diffusion-weighted (DW) MRI and 18F-fluorodeoxyglucose (18F-FDG) positron-emission tomography/computed tomography (PET/CT) with clinico-histopathological prognostic factors, disease-free survival (DFS) and overall survival (OS) in patients with cervical cancer. METHODS AND MATERIALS:Our institutional review board approved this retrospective study of 49 patients (median age, 45 years) with histopathologically proven IB-IVB International Federation of Gynecology and Obstetrics (FIGO) cervical cancer who underwent pre-treatment pelvic MRI and whole-body 18F-FDG PET/CT between February 2009 and May 2012. Maximum diameter (maxTD), percentage enhancement (PE) and mean apparent diffusion coefficient (ADCmean) of the primary tumor were measured on MRI. Maximum standardized uptake value (SUVmax), metabolic tumor volume (MTV), total lesion glycolysis (TLG) were measured on 18F-FDG PET/CT. Correlations between imaging metrics and clinico-histopathological parameters including revised 2009 FIGO stage, tumor histology, grade and lymph node (LN) metastasis at diagnosis were evaluated using the Wilcoxon rank sum test. Cox modeling was used to determine associations with DFS and OS. RESULTS:Median follow-up was 17 months. 41 patients (83.6%) were alive. 8 patients (16.3%) died of disease. Progression/recurrence occurred in 17 patients (34.6%). Significant differences were observed in ADCmean, SUVmax, MTV and TLG according to FIGO stage (p<0.001-0.025). There were significant correlations between ADCmean, MTV, TLG and LN metastasis (p=0.017-0.032). SUVmax was not associated with LN metastasis. FIGO stage (p=0.017/0.033), LN metastases (p=0.001/0.020), ADCmean (p=0.007/0.020) and MTV (p=0.014/0.026) were adverse predictors of both DFS/OS. maxTD (p=0.005) and TLG (p=0.024) were adverse predictors of DFS. PE and SUVmax did not correlate with DFS or OS (p=0.18-0.72). CONCLUSIONS:Quantitative parameters derived from pre-treatment DW-MRI (ADCmean) and from 18F-FDG PET/CT (MTV and TLG) were associated with high-risk features and may serve as prognostic biomarkers of survival in patients with cervical cancer.
journal_name
Eur J Radioljournal_title
European journal of radiologyauthors
Miccò M,Vargas HA,Burger IA,Kollmeier MA,Goldman DA,Park KJ,Abu-Rustum NR,Hricak H,Sala Edoi
10.1016/j.ejrad.2014.03.024subject
Has Abstractpub_date
2014-07-01 00:00:00pages
1169-1176issue
7eissn
0720-048Xissn
1872-7727pii
S0720-048X(14)00162-4journal_volume
83pub_type
杂志文章abstract：OBJECTIVES:To report our experience with transarterial glue embolization of the bronchial artery for life-threatening hemoptysis. MATERIALS AND METHODS:Twenty-five patients underwent bronchial artery embolization, using coaxial microcatheter technique, with a liquid agent, n-butyl-2-cyanoacrylate (NBCA), named glue, f...
journal_title：European journal of radiology
pub_type： 临床试验,杂志文章
doi：10.1016/j.ejrad.2008.10.017
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abstract：:A retrospective study of 624 lumbar myelographic and CT myelographic procedures was undertaken to evaluate the frequency, radiographic and clinical relevance of contrast medium outside the dural sac. Our findings indicate that epidural contrast is frequently identified on CT scans with highly sensitive window settings...
journal_title：European journal of radiology
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abstract：OBJECTIVE:To evaluate the prevalence of spoke-wheel pattern and typical symptoms of focal nodular hyperplasia (FNH) by means of dynamic contrast-enhanced ultrasonography (CEUS) in relation to lesion size. METHODS:Twenty-eight patients were included in the trial, in whom, based on the CEUS, we raised suspicion of hyper...
journal_title：European journal of radiology
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doi：10.1016/j.ejrad.2007.01.026
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abstract：BACKGROUND:Transcranial color-coded sonography (TCCS) allows the visualization of cerebral structures and enables monitoring of circulatory disorders occurring within the circle of Willis. OBJECTIVE:To verify whether TCCS is a reliable method in imaging intracerebral hemorrhages (ICHs) and to what degree its results a...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/j.ejrad.2011.02.066
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abstract：:A simple generalization of the diffraction enhanced imaging (DEI) technique, called generalized DEI (GDEI), and its application to tomographic imaging are herein presented. In planar imaging, the GDEI algorithm combines three input images (acquired at different analyzer positions) to deliver three parametric images, p...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/j.ejrad.2008.04.026
更新日期：2008-12-01 00:00:00
abstract：PURPOSE:To evaluate the awareness of radiation protection issues and the knowledge of dose levels of imaging procedures among medical students, radiology residents, and radiography students at an academic hospital. MATERIAL AND METHODS:A total of 159 young doctors and students (including 60 radiology residents, 56 med...
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abstract：BACKGROUND AND PURPOSE:The application of a fluid-attenuated inversion-recovery pulse with a conventional diffusion-weighted MRI sequence (FLAIR DWI) decreases the partial volume effects from cerebrospinal fluid on apparent diffusion coefficient (ADC) measurements. For this reason, FLAIR DWI may be more useful in the e...
journal_title：European journal of radiology
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doi：10.1016/j.ejrad.2009.11.029
更新日期：2010-08-01 00:00:00
abstract：:In 30 patients with rectal carcinoma the accuracy of computed tomography (CT) and endosonography (ES) was compared with the surgical specimen. Three cases were overstaged by ES and 4 cases were understaged by CT. The accuracy of ES was 84% and of CT only 76%. Both methods had advantages and limitations. An accurate st...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：
更新日期：1989-08-01 00:00:00
abstract：PURPOSE:To evaluate two different iodine concentrations of contrast material for detecting hypervascular hepatocellular carcinomas (HCCs) in cirrhotic liver by multi-detector row helical CT (MDCT) when a fixed contrast material volume and injection rate is used. MATERIALS AND METHODS:Institutional Review Board approva...
journal_title：European journal of radiology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ejrad.2010.10.006
更新日期：2011-12-01 00:00:00
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journal_title：European journal of radiology
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abstract：OBJECTIVE:To assess diaphragmatic motion during forced breathing in a health screening center cohort by time-resolved quantitative analysis using dynamic chest radiography and demonstrate the characteristics and associations with demographics and pulmonary function of participants. MATERIALS AND METHODS:This prospecti...
journal_title：European journal of radiology
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journal_title：European journal of radiology
pub_type： 杂志文章,评审
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更新日期：2016-11-01 00:00:00
abstract：:The purpose of this work was to investigate status of imaging technology and practice in five countries in Eastern-European region and evaluate the impact of IAEA projects on radiation protection of patients. Information collected using standardized IAEA protocol included status of technology, practices and patient do...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/j.ejrad.2011.03.075
更新日期：2011-08-01 00:00:00
abstract：:Image workstations will be the 'window' to the complex infrastructure of a PACS with its intertwined image modalities (image sources, image data bases and image processing devices) and data processing modalities (patient data bases, departmental and hospital information systems). They will serve for user-to-system dia...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/0720-048x(90)90146-3
更新日期：1990-05-01 00:00:00
abstract：:Teleradiology is probably the most successful eHealth service available today. Its business model is based on the remote transmission of radiological images (e.g. X-ray and CT-images) over electronic networks, and on the interpretation of the transmitted images for diagnostic purpose. Two basic service models are comm...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/j.ejrad.2009.10.018
更新日期：2010-01-01 00:00:00
abstract：:During cardiac angiography, hemodynamic alterations and surface electrocardiographic changes are common, predictable and dose-related adverse reactions to radiocontrast media. High osmolality, inadequate sodium content and local transient hypocalcemia are thought to be the main mechanisms responsible for these untowar...
journal_title：European journal of radiology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/0720-048x(94)90095-7
更新日期：1994-05-01 00:00:00
abstract：OBJECTIVE:To evaluate the technical success and immediate complication rates of temporary internal jugular vein (IJV) haemodialysis catheter placement in normal and high-risk patients. METHODS AND MATERIALS:Two-hundred and twenty temporary internal jugular vein catheters inserted under ultrasound guidance in 172 patie...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/j.ejrad.2004.10.004
更新日期：2005-07-01 00:00:00
abstract：BACKGROUND:The diffusion tensor imaging (DTI) parameters of the cervical spinal cord (CSC) changes with age. However, previous studies only examined specific CSC areas. OBJECTIVES:To analyze the DTI parameters in all intervertebral space levels of the whole normal CSC and to study the impact of age on these parameters...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/j.ejrad.2014.09.010
更新日期：2014-12-01 00:00:00
abstract：OBJECTIVE:Follow-up of aortic aneurysms by computed tomography (CT) is crucial to balance the risks of treatment and rupture. Artificial intelligence (AI)-assisted radiology reporting promises time savings and reduced inter-reader variabilities. METHODS:The influence of AI assistance on the efficiency and accuracy of ...
journal_title：European journal of radiology
pub_type： 杂志文章
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更新日期：2021-01-01 00:00:00
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journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/j.ejrad.2020.108847
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abstract：PURPOSE:We aimed to identify and assess cardiac abnormalities by cardiovascular magnetic resonance (CMR) in a non-ischaemic aborted sudden cardiac death (SCD) population and to establish possible predictors of SCD. METHODS:Thirty-six consecutive SCD survivors [median age 37.6 years (IQR 24.1-43.2), 31% female] with no...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/j.ejrad.2018.06.004
更新日期：2018-08-01 00:00:00
abstract：:The purpose of this study was to evaluate the agreement between axial, multiplanar reformatted (MPR) and semi-automated software measurements of pulmonary vein ostial diameters and distance to the first bifurcation. CT examinations of the thorax were retrospectively reviewed in 150 consecutive patients. The pulmonary ...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/j.ejrad.2008.04.008
更新日期：2009-07-01 00:00:00
abstract：:The authors discuss the controversy about mass screening for breast cancer in order to assess the soundness of a nationwide expansion of such programmes. Mass screening is second best because of the failure of prevention, therapeutic progress or ability to target high risk populations, but its efficacy reducing mortal...
journal_title：European journal of radiology
pub_type： 杂志文章,评审
doi：10.1016/s0720-048x(96)01143-6
更新日期：1997-02-01 00:00:00
abstract：PURPOSE:To evaluate the performance of F-18 FDG PET/CT in the detection of bone metastasis in non-small cell lung cancer (NSCLC) patients. MATERIALS AND METHODS:Three hundred and sixty-two consecutive NSCLC patients who underwent F-18 FDG PET/CT scanning were retrospectively analyzed. Each image of PET/CT, combined CT...
journal_title：European journal of radiology
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doi：10.1016/j.ejrad.2009.01.036
更新日期：2010-04-01 00:00:00
abstract：:Tuberous sclerosis is an uncommon heredito-familial disease. A rare case of multiple organ involvement is reported. ...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/s0720-048x(96)01074-1
更新日期：1997-07-01 00:00:00
abstract：:Degenerative and overuse diseases as well as impingement syndromes of the hand are illustrated and discussed in this review article. Osteoarthritis of the interphalangeal joints as described by Heberden and Bouchard is a ubiquitous articular disease often associated with synovitis and erosive joint destruction. Osteoa...
journal_title：European journal of radiology
pub_type： 杂志文章,评审
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更新日期：1997-09-01 00:00:00
abstract：OBJECTIVE:To verify the clinical outcomes of applying water swallowing to MR esophagography. METHODS:Thirty patients confirmed postoperatively or histopathologically with thoracic esophageal carcinoma by endoscopic biopsy and 10 healthy volunteers with normal esophagus underwent respectively conventional magnetic reso...
journal_title：European journal of radiology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ejrad.2011.05.010
更新日期：2012-09-01 00:00:00
abstract：INTRODUCTION:Parosteal osteosarcomas and well-differentiated liposarcomas (WDLPS) of soft tissue share several features: they are slowly progressive, locally aggressive tumors, tend to recur locally, and rarely or never metastasizes if not dedifferentiated. Their treatment is wide surgical resection. Microscopically, b...
journal_title：European journal of radiology
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doi：10.1016/j.ejrad.2011.11.035
更新日期：2013-12-01 00:00:00
abstract：OBJECTIVES:Diagnosing acute pancreatitis (AP) may be challenging in patients with acute abdominal pain but missing threefold increased serum lipase levels (Lip-). This studyaims both to characterize these patients using clinical, radiological and mortality data, and to assess the group of patients who need contrast-enh...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/j.ejrad.2017.08.038
更新日期：2017-10-01 00:00:00
abstract：:Despite the growing role of imaging, trauma remains the leading cause of death in people below the age of 45 years in the western industrialized countries. Trauma has been touted as the largest epidemic in the 20th century. The advent of MDCT has been the greatest advance in trauma care in the last 25 years. However, ...
journal_title：European journal of radiology
pub_type： 杂志文章,评审
doi：10.1016/j.ejrad.2008.08.014
更新日期：2008-12-01 00:00:00
