Effects of taurine on kindled amygdaloid seizures in rats, cats, and photosensitive baboons.

abstract：:This chapter covers the syndromes of benign epilepsy with centrotemporal spikes (BECTS), nonlesional focal epilepsy in otherwise normal children (NLFN), and the genetic generalized epilepsies. BECTS is an epilepsy syndrome that always enters terminal remission before the general age of a planned transition of adolesce...

journal_title：Epilepsia

authors： Camfield CS,Berg A,Stephani U,Wirrell EC

更新日期：2014-08-01 00:00:00

abstract：:The combination of phenobarbital (PB) and phenytoin (PHT) was recommended for many years for treatment of epilepsy in humans. We tested the effectiveness of the combination in a model of hippocampal seizures termed maximal dentate activation (MDA). Two parameters of MDA were measured: duration and time to onset. Neith...

journal_title：Epilepsia

authors： Stringer JL,Higgins MG

更新日期：1994-01-01 00:00:00

abstract：:Severe early onset epilepsies are often caused by de novo pathogenic variants. Few studies have reported the frequency of somatic mosaicism in parents of children with severe epileptic encephalopathies. Here we aim to investigate the frequency of mosaicism in the parents of children with epilepsy caused by alleged de ...

journal_title：Epilepsia

authors： Møller RS,Liebmann N,Larsen LHG,Stiller M,Hentschel J,Kako N,Abdin D,Di Donato N,Pal DK,Zacher P,Syrbe S,Dahl HA,Lemke JR

更新日期：2019-06-01 00:00:00

abstract：:Gene expression profiles in brain and blood of animals and humans can be useful for diagnosis, prognosis, and treatment of epilepsy. This article reviews recent progress and prospects for the future. ...

journal_title：Epilepsia

authors： Sharp FR,Lit L,Xu H,Apperson M,Walker W,Wong B,Gilbert DL,Hershey A,Glauser TA

更新日期：2006-10-01 00:00:00

abstract：PURPOSE:To validate a brief screening instrument for identifying people with epilepsy in epidemiologic or genetic studies. METHODS:We designed a nine-question screening instrument for epilepsy and administered it by telephone to individuals with medical record-documented epilepsy (lifetime history of >or=2 unprovoked ...

journal_title：Epilepsia

authors： Ottman R,Barker-Cummings C,Leibson CL,Vasoli VM,Hauser WA,Buchhalter JR

更新日期：2010-02-01 00:00:00

abstract：:Spontaneously epileptic rats (SER) are a double mutant (zi/zi, tm/tm) spontaneously exhibiting both tonic and absence-like seizures. We examined the long-term effects of continual intake of phenobarbital (PB) on SER as a method of assessing long-term evaluation of antiepileptic drugs (AEDs). Food pellets containing 0....

journal_title：Epilepsia

authors： Serikawa T,Kogishi K,Yamada J,Ohno Y,Ujihara H,Fujita Y,Sasa M,Takaori S

更新日期：1990-01-01 00:00:00

abstract：OBJECTIVE:Autoantibodies against glutamic acid decarboxylase (GAD) and the voltage-gated potassium channel (VGKC) complex are associated with distinct subtypes of limbic encephalitis regarding clinical presentation, response to therapy, and outcome. The aim of this study was to investigate white matter changes in these...

journal_title：Epilepsia

authors： Wagner J,Schoene-Bake JC,Witt JA,Helmstaedter C,Malter MP,Stoecker W,Probst C,Weber B,Elger CE

更新日期：2016-03-01 00:00:00

abstract：:Autoantibodies to surface proteins that influence neuronal excitability are increasingly found in different forms of epilepsy or encephalitis in adults, and are also beginning to be identified in children. The conditions are often refractory to traditional antiepileptic drugs. Detection of these antibodies can help to...

journal_title：Epilepsia

authors： Vincent A,Irani SR,Lang B

更新日期：2011-10-01 00:00:00

abstract：PURPOSE:Compare annual direct and indirect costs between privately insured U.S. patients with epileptic partial onset seizures (POS) and matched controls. METHODS:One thousand eight hundred fifty-nine patients (including a subset of 758 employees) with >or=1 (POS) diagnosis (ICD-9-CM: 345.4.x-345.7.x), 1999-2004, ages...

journal_title：Epilepsia

authors： Ivanova JI,Birnbaum HG,Kidolezi Y,Qiu Y,Mallett D,Caleo S

更新日期：2010-05-01 00:00:00

abstract：:We investigated the electrophysiological effects of high-frequency anterior thalamic deep brain stimulation using intracerebral mesial and lateral temporal depth electrodes in a patient with intractable focal epilepsy. Monopolar and bipolar stimulation delivered to the thalamic anterior nucleus using the programmable ...

journal_title：Epilepsia

authors： Zumsteg D,Lozano AM,Wennberg RA

更新日期：2006-11-01 00:00:00

abstract：PURPOSE:Polymicrogyria (PMG) is an epileptogenic malformation of cortical development. We describe the clinical epilepsy and imaging features of a large cohort with PMG-related epilepsy. METHODS:Participants were recruited through the Epilepsy Phenome/Genome Project, a multicenter collaborative effort to collect detai...

journal_title：Epilepsia

authors： Shain C,Ramgopal S,Fallil Z,Parulkar I,Alongi R,Knowlton R,Poduri A,EPGP Investigators.

更新日期：2013-08-01 00:00:00

abstract：:Four groups of pregnant rats were used to study the effects of dietary supplements of folic acid (FA) alone or a mixture of FA, vitamins (Vit), and amino acids (AA) on the teratogenic effects of phenytoin (PHT). Groups A, B, and C received intraperitoneal (i.p.) injections of high-dose (75 mg/kg/day) phenytoin (PHT) b...

journal_title：Epilepsia

authors： Zhu MX,Zhou SS

更新日期：1989-03-01 00:00:00

abstract：OBJECTIVE:To evaluate the incidence of new onset epilepsy and associated risk factors in patients with periodic patterns on continuous electroencephalography (cEEG) during critical illness. METHODS:The local cEEG database and then medical records were reviewed from January 1, 2013 to June 30, 2013 to find adult patien...

journal_title：Epilepsia

authors： Punia V,Bena J,Krishnan B,Newey C,Hantus S

更新日期：2018-08-01 00:00:00

abstract：:Early in these proceedings, the origin of the three terms in the title, "idiopathic generalized epilepsy," is discussed with respect to their significance over time, and typical misunderstandings. In the mid-20th century, a rather chaotic use of a multitude of often loosely defined terms had developed, which increasin...

journal_title：Epilepsia

authors： Wolf P

更新日期：2005-01-01 00:00:00

abstract：:The fragile X mental retardation 1 gene (Fmr1) is polymorphic for CGG trinucleotide repeat number in the 5'-untranslated region, with repeat lengths <45 associated with typical development and repeat lengths >200 resulting in hypermethylation and transcriptional silencing of the gene and mental retardation in the frag...

journal_title：Epilepsia

authors： Berman RF,Murray KD,Arque G,Hunsaker MR,Wenzel HJ

更新日期：2012-06-01 00:00:00

abstract：:Neurotrophic factors are involved in the survival of neurons as well as in the proliferation and differentiation of neuronal precursors. Therefore, modulating their levels in lesion areas may exert favorable effects on seizure-induced damage. However, it is unclear if damage limitation or repair may prevent epileptoge...

journal_title：Epilepsia

authors： Simonato M,Zucchini S

更新日期：2010-07-01 00:00:00

abstract：:We determined changes in serum concentrations of thyroid hormones during carbamazepine (CBZ) therapy during a 5-year prospective follow-up study of 20 patients with newly diagnosed epilepsy. In addition, we evaluated the effects of replacing CBZ with oxcarbazepine (OCBZ) in 12 male patients with epilepsy in a 6-month ...

journal_title：Epilepsia

authors： Isojärvi JI,Airaksinen KE,Mustonen JN,Pakarinen AJ,Rautio A,Pelkonen O,Myllylä VV

更新日期：1995-08-01 00:00:00

abstract：PURPOSE:To determine both the efficacy of and compliance with the ketogenic diet in the adolescent population. METHODS:A retrospective study of 45 patients, aged 12-19 years, consecutively enrolled in a ketogenic diet program from 1994 to 2002, was performed. Thirty-seven patients were from The Johns Hopkins Medical I...

journal_title：Epilepsia

authors： Mady MA,Kossoff EH,McGregor AL,Wheless JW,Pyzik PL,Freeman JM

更新日期：2003-06-01 00:00:00

abstract：PURPOSE:A survey was made of a network of 14 epilepsy centers in Italy to assess whether integrated diagnosis and treatment monitoring led to a more precise syndromic classification of the patients and a better response to treatment. METHODS:Data on the diagnosis and treatment of epilepsy and the degree of seizure con...

journal_title：Epilepsia

authors：

更新日期：1997-12-01 00:00:00

abstract：:Rufinamide (RUF) is a novel antiepileptic drug considered as second-line therapy in the treatment of Lennox-Gastaut syndrome. Treatment-emergent adverse events (AEs) have consisted mainly of drowsiness, irritability, vomiting, and loss of appetite. RUF is considered as a "weight-neutral" drug. We found clinically sign...

journal_title：Epilepsia

authors： Mourand I,Crespel A,Gelisse P

更新日期：2013-01-01 00:00:00

abstract：PURPOSE:The aim of this study was to examine the impact of clinical variables, particularly age at onset of epilepsy, on intellectual function in a group of children with temporal lobe epilepsy (TLE). METHODS:We reviewed the preoperative neuropsychological test results of 79 children with unilateral TLE who subsequent...

journal_title：Epilepsia

authors： Cormack F,Cross JH,Isaacs E,Harkness W,Wright I,Vargha-Khadem F,Baldeweg T

更新日期：2007-01-01 00:00:00

abstract：PURPOSE:Hippocampal sclerosis (HS) is the most common pathologic finding in intractable temporal lobe epilepsy (TLE). In many patients, HS is accompanied by an extrahippocampal lesion (EHL). We sought to assess the lobar distribution and side of EHLs in relation to HS in a large consecutive series of patients presentin...

journal_title：Epilepsia

authors： Hofman PA,Fitt G,Mitchell LA,Jackson GD

更新日期：2011-04-01 00:00:00

abstract：:The ultimate treatment goal in epilepsy therapy is always freedom from seizures with as few treatment adverse effects as possible. If seizures persist with the first monotherapy, alternative monotherapy with another antiepileptic drug (AED) should be considered. Continuing seizures should lead to a reevaluation of dif...

journal_title：Epilepsia

authors： Ben-Menachem E

更新日期：2014-01-01 00:00:00

abstract：:Medically intractable tonic and atonic seizures may be responsive to either vagus nerve stimulation (VNS) or corpus callosum section. VNS has been shown to be effective and is associated with very low morbidity. Callosotomy is a more ambitious procedure, with a higher risk of complications but greater likelihood of se...

journal_title：Epilepsia

authors： Rosenfeld WE,Roberts DW

更新日期：2009-09-01 00:00:00

abstract：:No reports of the Washington Psychosocial Seizure Inventory (WPSI) have yet been presented from Asian countries in detail. We performed a multiinstitutional study of this test in 652 Japanese subjects. The mean value of the Lie Scale was high, and only one third of our subjects were under the limit of the original cri...

journal_title：Epilepsia

authors： Hosokawa K,Kugoh T,Mino S

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Inducing sleep deprivation is supposed to increase interictal epileptic discharges on EEGs from children suspected of having epilepsy. Although it is supposed that depriving a child from sleep is a burden for both child and parent, this assumption has not been investigated in any study so far. M...

journal_title：Epilepsia

authors： Nijhof SL,Bakker AL,Van Nieuwenhuizen O,Oostrom K,van Huffelen AC

更新日期：2005-08-01 00:00:00

abstract：:The aim was to systematically review studies that have focused on symptoms of anxiety reported by parents of children (0-18 years) with epilepsy. PubMed was used to identify relevant studies. Selected studies were reviewed with respect to prevalence of above threshold scores and comparisons with controls on standardiz...

journal_title：Epilepsia

authors： Jones C,Reilly C

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVE:The need for alternative pharmacologic strategies in treatment of epilepsies is pressing for about 30% of patients with epilepsy who do not experience satisfactory seizure control with present treatments. In temporal lobe epilepsy (TLE) even up to 80% of patients are pharmacoresistant, and surgical resection ...

journal_title：Epilepsia

authors： Klaft ZJ,Hollnagel JO,Salar S,Calişkan G,Schulz SB,Schneider UC,Horn P,Koch A,Holtkamp M,Gabriel S,Gerevich Z,Heinemann U

更新日期：2016-05-01 00:00:00

abstract：PURPOSE:To evaluate the effect of stress on seizure frequency in childhood epilepsy, and to assess possible differences between children in whom seizures are precipitated by stress and those in whom they are not. METHODS:Parents or caregivers of children with active epilepsy (aged 2-16 years) were sent questionnaires ...

journal_title：Epilepsia

authors： van Campen JS,Jansen FE,Steinbusch LC,Joëls M,Braun KP

更新日期：2012-09-01 00:00:00

abstract：OBJECTIVE:To determine predictors of focal to bilateral tonic-clonic seizures (FBTCS) during video-electroencephalography (EEG) monitoring (VEM). METHODS:All adult patients undergoing presurgical VEM from 2014 to 2015 in the department of epileptology were eligible (N = 229). Those with refractory focal epilepsy and e...

journal_title：Epilepsia

authors： Pensel MC,Schnuerch M,Elger CE,Surges R

更新日期：2020-03-01 00:00:00