Washington Psychosocial Seizure Inventory: a multiinstitutional study in Japan.

abstract：:Four groups of pregnant rats were used to study the effects of dietary supplements of folic acid (FA) alone or a mixture of FA, vitamins (Vit), and amino acids (AA) on the teratogenic effects of phenytoin (PHT). Groups A, B, and C received intraperitoneal (i.p.) injections of high-dose (75 mg/kg/day) phenytoin (PHT) b...

journal_title：Epilepsia

authors： Zhu MX,Zhou SS

更新日期：1989-03-01 00:00:00

abstract：PURPOSE:Benign rolandic epilepsy (BRE) is considered a genetically determined idiopathic partial epilepsy. We analyzed a large sample of twins from four international twin registers to probe the genetics of BRE. We also aim to synthesize the apparently conflicting family and twin data into a model of BRE etiology. MET...

journal_title：Epilepsia

authors： Vadlamudi L,Kjeldsen MJ,Corey LA,Solaas MH,Friis ML,Pellock JM,Nakken KO,Milne RL,Scheffer IE,Harvey AS,Hopper JL,Berkovic SF

更新日期：2006-03-01 00:00:00

abstract：:Focal epilepsy can present with a rapidly progressing course of intractable epilepsy in children. We present a typical example of such a patient with focal seizures due to a frontal lobe cortical lesion of developmental origin. MRI and SPECT revealed abnormalities in the right frontal lobe. Surgical resection resulted...

journal_title：Epilepsia

authors： Kuzniecky R

更新日期：2004-01-01 00:00:00

abstract：PURPOSE:To evaluate prospectively patient's aims for epilepsy surgery as previously outlined theoretically by Taylor et al. (Epilepsia 1997;3:625-30). METHODS:Ninety-three consecutive patients were interviewed by a psychiatrist as part of their evaluation for epilepsy surgery. Open-ended questions about the patient we...

journal_title：Epilepsia

authors： Taylor DC,McMacKin D,Staunton H,Delanty N,Phillips J

更新日期：2001-05-01 00:00:00

abstract：OBJECTIVES:To validate and translate the English version of the Neurologic Depression Disorders Inventory in Epilepsy (NDDI-E) into Spanish as a screening instrument for major depressive episodes (MDE) for patients with epilepsy from Argentina and Uruguay. METHODS:One hundred fifty-five consecutive outpatients with ep...

journal_title：Epilepsia

authors： Thomson AE,Calle A,Fontela ME,Yepez L,Muñoz Giacomelli F,Jáuregui A,Racosta JM,Kanner AM

更新日期：2014-02-01 00:00:00

abstract：OBJECTIVE:There are limited data on the indications for the use of chronic invasive electroencephalography (EEG) monitoring (IEM) for pediatric epilepsy surgery. METHODS:We retrospectively studied 102 children who underwent intracranial monitoring to map critical cortex, localize the epileptogenic region, or resolve d...

journal_title：Epilepsia

authors： Brna P,Duchowny M,Resnick T,Dunoyer C,Bhatia S,Jayakar P

更新日期：2015-07-01 00:00:00

abstract：:Monotherapy is the policy for management of patients with epilepsy. With increasing knowledge of the biology of epilepsy and of the modes of action of antiepileptic drugs (AEDs), this concept must be reevaluated. When monotherapy fails to control seizures, subsequent treatment should be based on "rational pharmacology...

journal_title：Epilepsia

authors： de Bittencourt PR,Mazer S,Marcourakis T,Bigarella MM,Ferreira ZS,Mumford JP

更新日期：1994-03-01 00:00:00

abstract：OBJECTIVE:To explore the structure-function relation of the temporal lobe in newly diagnosed West syndrome of unknown cause (uWS). METHODS:Quantitative magnetic resonance imaging (three-dimensional [3D] structural MRI and diffusion tensor imaging [DTI]) was analyzed using voxel-based morphometry (VBM) and tract-based ...

journal_title：Epilepsia

authors： Fosi T,Chu C,Chong WK,Clark C,Scott RC,Boyd S,De Haan M,Neville B

更新日期：2015-04-01 00:00:00

abstract：PURPOSE:Felbamate (FBM) is a new antiepileptic drug (AED) that is often effective in seizure disorders refractory to other treatments; its use has been greatly restricted after cases of aplastic anemia were reported. To elucidate the putative association between FBM and aplastic anemia, we made a detailed evaluation of...

journal_title：Epilepsia

authors： Kaufman DW,Kelly JP,Anderson T,Harmon DC,Shapiro S

更新日期：1997-12-01 00:00:00

abstract：:All inpatients aged greater than 55 years with dementia in the Dundee Psychiatric Service were surveyed for seizure occurrence by interviewing staff and reviewing records. Of 208 patients, 19 (9.1%) were recorded as having seizures. The seizures were major in 92% and occurred at a rate of approximately 2.3 seizures pe...

journal_title：Epilepsia

authors： McAreavey MJ,Ballinger BR,Fenton GW

更新日期：1992-07-01 00:00:00

abstract：:Severe early onset epilepsies are often caused by de novo pathogenic variants. Few studies have reported the frequency of somatic mosaicism in parents of children with severe epileptic encephalopathies. Here we aim to investigate the frequency of mosaicism in the parents of children with epilepsy caused by alleged de ...

journal_title：Epilepsia

authors： Møller RS,Liebmann N,Larsen LHG,Stiller M,Hentschel J,Kako N,Abdin D,Di Donato N,Pal DK,Zacher P,Syrbe S,Dahl HA,Lemke JR

更新日期：2019-06-01 00:00:00

abstract：:We report the history of a 14-year-old girl with atypical childhood occipital epilepsy "Gastaut type" whose first generalized tonic-clonic seizure was preceded by migraine without aura and followed by a status migrainosus. This status lasted for 3 days despite standard analgesic therapy. An EEG recording revealed an o...

journal_title：Epilepsia

authors： Parisi P,Kasteleijn-Nolst Trenité DG,Piccioli M,Pelliccia A,Luchetti A,Buttinelli C,Villa MP

更新日期：2007-11-01 00:00:00

abstract：:Sudden unexplained death syndrome (SUDS) accounts for about 10% of deaths in patients with epilepsy. It is associated with subtherapeutic postmortem serum antiepileptic drug (AED) levels but no anatomic cause of death on autopsy. The mechanisms of death are not known. We investigated 44 cases of SUDS for details of se...

journal_title：Epilepsia

authors： Earnest MP,Thomas GE,Eden RA,Hossack KF

更新日期：1992-03-01 00:00:00

abstract：PURPOSE:The present study aimed to clarify the effect of electrical stimulation and lesioning of the anterior nucleus of the thalamus (ANT) on kainic acid (KA)-induced focal cortical seizures in a rat model. To address the mechanism underlying these anticonvulsant actions, cerebral glucose metabolism after ANT electric...

journal_title：Epilepsia

authors： Takebayashi S,Hashizume K,Tanaka T,Hodozuka A

更新日期：2007-02-01 00:00:00

abstract：:Twenty-seven patients with medically refractory paroxysmal disorders underwent EEG-video-audio (EVA) monitoring in an inpatient neurology-neurosurgery unit over 1-15 (mean 8.9) days. Fast visual review of all EEG records (5,784 h) and subsequent analysis of synchronized EVA patterns demonstrated a total of 208 partial...

journal_title：Epilepsia

authors： Pierelli F,Chatrian GE,Erdly WW,Swanson PD

更新日期：1989-09-01 00:00:00

abstract：:In this study, we aimed to investigate the types of seizures and epilepsy associated with systemic lupus erythematosus (SLE). We searched the medical records at a tertiary referral center to identify a cohort of epilepsy patients with SLE who were treated between January 2000 and August 2011. We analyzed the clinical ...

journal_title：Epilepsia

authors： Toyota T,Akamatsu N,Tanaka A,Shouzaki T,Tsuji S,Saito K,Tanaka Y

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVE:The objective was to systematically review studies that have focused on behavioral and emotional functioning before (baseline) and after (follow-up) pediatric epilepsy surgery. METHODS:The systematic review was carried out according to PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyse...

journal_title：Epilepsia

authors： Reilly C,Baldeweg T,Stewart N,Wadhwani S,Jones C,Helen Cross J,Heyman I

更新日期：2019-05-01 00:00:00

abstract：:Recent clinical trials indicate that cannabidiol (CBD) may reduce seizure frequency in pediatric patients with certain forms of treatment-resistant epilepsy. Many of these patients experience significant impairments in quality of life (QOL) in physical, mental, and social dimensions of health. In this study, we measur...

journal_title：Epilepsia

authors： Rosenberg EC,Louik J,Conway E,Devinsky O,Friedman D

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVE:Previous studies examining seizures in patients with 22q11.2 deletion syndrome (22q11.2DS) have focused primarily on children and adolescents. In this study we investigated the prevalence and characteristics of seizures and epilepsy in an adult 22q11.2DS population. METHODS:The medical records of 202 adult p...

journal_title：Epilepsia

authors： Wither RG,Borlot F,MacDonald A,Butcher NJ,Chow EWC,Bassett AS,Andrade DM

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVES:Patients with temporal lobe epilepsy (TLE) experience significant deficits in category-related object recognition and naming following standard surgical approaches. These deficits may result from a decoupling of core processing modules (e.g., language, visual processing, and semantic memory), due to "collate...

journal_title：Epilepsia

authors： Drane DL,Loring DW,Voets NL,Price M,Ojemann JG,Willie JT,Saindane AM,Phatak V,Ivanisevic M,Millis S,Helmers SL,Miller JW,Meador KJ,Gross RE

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:The aim of this study was to assess the regional relative interictal and postictal perfusion changes in temporal and parietal lobe epilepsy. METHODS:We investigated interictal and postictal magnet resonance perfusion changes in five patients with temporal lobe epilepsy either with hippocampal sclerosis (n = 3)...

journal_title：Epilepsia

authors： Leonhardt G,de Greiff A,Weber J,Ludwig T,Wiedemayer H,Forsting M,Hufnagel A

更新日期：2005-12-01 00:00:00

abstract：:Development of tolerance (i.e., the reduction in response to a drug after repeated administration) is an adaptive response of the body to prolonged exposure to the drug, and tolerance to antiepileptic drugs (AEDs) is no exception. Tolerance develops to some drug effects much more rapidly than to others. The extent of ...

journal_title：Epilepsia

authors： Löscher W,Schmidt D

更新日期：2006-08-01 00:00:00

abstract：:Our previous finding that intracerebroventricular (i.c.v.) administration of both thyrotropin-releasing hormone (TRH) and its analogue, gamma-butyrolactone-gamma-carbonyl-L-histidyl-L-prolinamide citrate (DN-1417), suppressed seizure development of amygdaloid (AM) kindling and kindled AM seizures leads to a new hypoth...

journal_title：Epilepsia

authors： Kajita S,Ogawa N,Sato M

更新日期：1987-05-01 00:00:00

abstract：PURPOSE:Angelman syndrome (AS) is a neurogenetic disorder characterized by developmental delay and a frequently refractory epileptic condition. Valproate, clonazepam and/or phenytoin are said to be the most effective antiepileptic drugs (AEDs) against the seizures in AS. Experience with the newer AEDs is very limited d...

journal_title：Epilepsia

authors： Dion MH,Novotny EJ Jr,Carmant L,Cossette P,Nguyen DK

更新日期：2007-03-01 00:00:00

abstract：:Epilepsy can be a devastating disorder. In addition to debilitating seizures, epilepsy can cause cognitive and emotional problems with reduced quality of life. Therefore, the major aim is to prevent the disorder in the first place: identify, detect, and reverse the processes responsible for its onset, and monitor and ...

journal_title：Epilepsia

authors： Koepp MJ,Årstad E,Bankstahl JP,Dedeurwaerdere S,Friedman A,Potschka H,Ravizza T,Theodore WH,Baram TZ

更新日期：2017-07-01 00:00:00

abstract：PURPOSE:To characterize seizure types and electroencephalographic features of glucose transporter type 1 deficiency syndrome (Glut-1 DS). METHODS:Twenty children with clinical and laboratory features of Glut-1 DS were evaluated. Age at seizure diagnosis, seizure classification, and response to treatment were determine...

journal_title：Epilepsia

authors： Leary LD,Wang D,Nordli DR Jr,Engelstad K,De Vivo DC

更新日期：2003-05-01 00:00:00

abstract：:The effects of cannabidiol (CBD) on electrically evoked kindled seizures were studied in conscious, unrestrained rats with chronically implanted cortical and limbic electrodes, and the results were compared with those of delta 9-tetrahydrocannabinol (delta 9-THC), phenytoin (PHT), and ethosuximide (ESM). All drugs wer...

journal_title：Epilepsia

authors： Turkanis SA,Smiley KA,Borys HK,Olsen DM,Karler R

更新日期：1979-08-01 00:00:00

abstract：PURPOSE:The acute, subacute, and chronic effects of vigabatrin (VGB) were studied in patients with refractory complex partial seizures. VGB increases human brain gamma-aminobutyric acid (GABA) and the related metabolites, homocarnosine and 2-pyrrolidinone. METHODS:In vivo measurements of GABA and homocarnosine were ma...

journal_title：Epilepsia

authors： Petroff OA,Hyder F,Collins T,Mattson RH,Rothman DL

更新日期：1999-07-01 00:00:00

abstract：:Pinealectomy of the Mongolian gerbil leads to seizure activity. The pineal gland is a major source of malatonin (5-methoxy-N-acetyltryptamine) which may possess a modulatory influence upon neural activity. Melatonin administered in the form of subcutaneous beeswax implants was given to gerbils four days prior to pinea...

journal_title：Epilepsia

authors： Rudeen PK,Philo RC,Symmes SK

更新日期：1980-04-01 00:00:00

abstract：PURPOSE:Dravet syndrome (DS) or severe myoclonic epilepsy of infancy is an intractable epileptic encephalopathy of early childhood that is caused by a mutation in the SCN1A gene in most patients. The aim of this study was to identify a syndrome-specific epileptic network underlying interictal epileptiform discharges (I...

journal_title：Epilepsia

authors： Moehring J,von Spiczak S,Moeller F,Helbig I,Wolff S,Jansen O,Muhle H,Boor R,Stephani U,Siniatchkin M

更新日期：2013-05-01 00:00:00