Long-term effects of continual intake of phenobarbital on the spontaneously epileptic rat.

abstract：:Our study investigated public attitudes toward epilepsy, and knowledge and understanding of epilepsy in Hungary. We compared changes of public attitudes in the last six years, hypothesizing a trend of positive changes because of recent national initiatives for acceptance and integration of people with epilepsy (e.g., ...

journal_title：Epilepsia

authors： Mirnics Z,Czikora G,Závecz T,Halász P

更新日期：2001-01-01 00:00:00

abstract：PURPOSE:To evaluate the changes in serum sex hormones of gonadal or adrenal origin, the gonadotropic hormones, and sex hormone-binding globulin (SHBG) in men and women with chronic temporal lobe epilepsy (TLE), who are undergoing monotherapy with carbamazepine or receiving carbamazepine in combination with other antico...

journal_title：Epilepsia

authors： Stoffel-Wagner B,Bauer J,Flügel D,Brennemann W,Klingmüller D,Elger CE

更新日期：1998-11-01 00:00:00

abstract：PURPOSE:Epileptic spasms are seizures that occur predominantly in children and are characterized by clusters of brief axial movements. Epileptic spasms may occur in the context of a variety of syndromes. Previous research has found that epileptic spasms occur in a sleep/wake and diurnal rhythm. The purpose of this stud...

journal_title：Epilepsia

authors： Ramgopal S,Shah A,Zarowski M,Vendrame M,Gregas M,Alexopoulos AV,Loddenkemper T,Kothare SV

更新日期：2012-07-01 00:00:00

abstract：PURPOSE:To assess the efficacy and safety of multiple subpial transection (MST), a new technique in epilepsy surgery, alone and in combination with resection. METHODS:MST was performed in 22 patients with intractable epilepsy, 10 of whom were treated with a combination of a resection and MST in functionally important ...

journal_title：Epilepsia

authors： Hufnagel A,Zentner J,Fernandez G,Wolf HK,Schramm J,Elger CE

更新日期：1997-06-01 00:00:00

abstract：PURPOSE:Some evidence suggests that levetiracetam (LEV) possesses antiepileptogenic characteristics. The purpose of this study was to investigate the time course of seizure protection by LEV compared with that of phenytoin (PHT), phenobarbital (PB), valproate (VPA), and carbamazepine (CBZ) in the spontaneously epilepti...

journal_title：Epilepsia

authors： Ji-qun C,Ishihara K,Nagayama T,Serikawa T,Sasa M

更新日期：2005-09-01 00:00:00

abstract：PURPOSE:Intracerebral vascular malformations including cavernous angiomas (CAs) and arteriovenous malformations (AVMs) are an important cause of chronic pharmacoresistant epilepsies. Little is known about the pathogenetic basis of epilepsy in patients with vascular malformations. Intracerebral deposits of iron-containi...

journal_title：Epilepsia

authors： Raabe A,Schmitz AK,Pernhorst K,Grote A,von der Brelie C,Urbach H,Friedman A,Becker AJ,Elger CE,Niehusmann P

更新日期：2012-03-01 00:00:00

abstract：PURPOSE:To evaluate how diagnostic criteria influence remission rates for patients with childhood absence epilepsy (CAE) and to assess clinical and EEG parameters as predictors of outcome. METHODS:One hundred nineteen patients were diagnosed with CAE, according to International League Against Epilepsy (ILAE) classific...

journal_title：Epilepsia

authors： Grosso S,Galimberti D,Vezzosi P,Farnetani M,Di Bartolo RM,Bazzotti S,Morgese G,Balestri P

更新日期：2005-11-01 00:00:00

abstract：:The Epilepsy Association of Maryland, an affiliate of the Epilepsy Foundation of America (EFA), recognized that the Maryland state regulations and laws on driving licensing restricted the rights of individuals with epilepsy. After identifying the problem, the Association determined the needed changes and planned a leg...

journal_title：Epilepsia

authors： Kingham LA

更新日期：1994-05-01 00:00:00

abstract：PURPOSE:Upper extremity automatisms are considered to be an ipsilateral seizure lateralizing sign in temporal lobe epilepsy (TLE). Herein we describe different types of contralateral upper extremity automatisms (CUEAs). METHODS:One hundred ninety-three video-(electroencephalography) EEG recordings of 59 patients were ...

journal_title：Epilepsia

authors： Kelemen A,Fogarasi A,Borbély C,Szucs A,Fabó D,Jakus R,Rásonyi G,Halász P

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVE:To evaluate efficacy, tolerability, and safety of adjunctive brivaracetam (BRV) in patients with Unverricht-Lundborg disease (EPM1). METHODS:Two prospective, multicenter, double-blind, phase III trials (N01187/NCT00357669; N01236/NCT00368251) in patients (≥16 years) with genetically ascertained EPM1, showing...

journal_title：Epilepsia

authors： Kälviäinen R,Genton P,Andermann E,Andermann F,Magaudda A,Frucht SJ,Schlit AF,Gerard D,de la Loge C,von Rosenstiel P

更新日期：2016-02-01 00:00:00

abstract：PURPOSE:Perimenstrual catamenial epilepsy may in part be due to withdrawal of the endogenous progesterone-derived neurosteroid allopregnanolone that potentiates gamma-aminobutyric acidA (GABA(A)) receptor-mediated inhibition. Here we sought to determine whether the anticonvulsant potencies of neuroactive steroids, benz...

journal_title：Epilepsia

authors： Reddy DS,Rogawski MA

更新日期：2001-03-01 00:00:00

abstract：OBJECTIVE:It has been suggested that multilobar epilepsies caused by lesions restricted to the posterior cerebral quadrant (ie, the parietal, temporal, and occipital lobes) can be treated successfully by a procedure termed posterior disconnection. The objective of the present paper was to identify determinants of the e...

journal_title：Epilepsia

authors： Kalbhenn T,Cloppenborg T,Wörmann FG,Blümcke I,Coras R,May TW,Polster T,Simon M,Bien CG

更新日期：2019-09-01 00:00:00

abstract：:In evaluation of patients with complex partial seizures who are candidates for surgical treatment, exact definition of the epileptogenic focus is essential for a good surgical outcome. We report a new technique which permits detailed mapping of the epileptogenic activity in the basal temporal lobe and the convexity of...

journal_title：Epilepsia

authors： Lüders H,Hahn J,Lesser RP,Dinner DS,Morris HH 3rd,Wyllie E,Friedman L,Friedman D,Skipper G

更新日期：1989-03-01 00:00:00

abstract：:A need for prevalence information emphasizing racial differences prompted a door-to-door survey of all residents of Copiah County, Mississippi. The fieldwork involved a complete census and an extensive screening questionnaire inquiring about diagnoses, signs, and symptoms of neurologic disease. Residents who lived in ...

journal_title：Epilepsia

authors： Haerer AF,Anderson DW,Schoenberg BS

更新日期：1986-01-01 00:00:00

abstract：PURPOSE:We studied the effect of vagus nerve stimulation (VNS) on seizure reduction in patients with intractable epilepsy with bilateral independent temporal lobe foci. METHODS:Ten patients who met the criterion of the presence of two distinctive clinical and ictal EEG seizure patterns were identified and followed up ...

journal_title：Epilepsia

authors： Alsaadi TM,Laxer KD,Barbaro NM,Marks WJ Jr,Garcia PA

更新日期：2001-07-01 00:00:00

abstract：PURPOSE:The multidrug resistance (mdr) gene family encodes the drug transport macromolecule P-glycoprotein (P-gp), which contributes to the functionality of the blood-brain barrier. Recent evidence suggests that P-gp-mediated drug extrusion may play a facilitatory role in refractory epilepsy. We investigated the region...

journal_title：Epilepsia

authors： Kwan P,Sills GJ,Butler E,Gant TW,Meldrum BS,Brodie MJ

更新日期：2002-11-01 00:00:00

abstract：PURPOSE:The aims of the present study were to explore the relation between ictal scalp EEG patterns and ictal hyperperfusion patterns in patients with unilateral hippocampal sclerosis-associated mesial temporal lobe epilepsy (HS-MTLE) by using semiquantitative single-photon emission computed tomography (SPECT) analysis...

journal_title：Epilepsia

authors： Kim JH,Im KC,Kim JS,Lee SA,Lee JK,Khang SK,Kang JK

更新日期：2007-02-01 00:00:00

abstract：PURPOSE:To investigate brain electrical activity in Q54 mice that display spontaneous seizures because of a gain-of-function mutation of the Scn2a sodium channel gene, and to evaluate the efficacy of low frequency deep brain stimulation (DBS) for seizure frequency reduction. METHODS:Electroencephalography (EEG), elect...

journal_title：Epilepsia

authors： Kile KB,Tian N,Durand DM

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVE:Seizures are common in individuals with duplications of chromosome 15q11.2-q13 (Dup15q). The goal of this study was to examine the phenotypes and treatments of seizures in Dup15q in a large population. METHODS:A detailed electronic survey was conducted through the Dup15q Alliance containing comprehensive que...

journal_title：Epilepsia

authors： Conant KD,Finucane B,Cleary N,Martin A,Muss C,Delany M,Murphy EK,Rabe O,Luchsinger K,Spence SJ,Schanen C,Devinsky O,Cook EH,LaSalle J,Reiter LT,Thibert RL

更新日期：2014-03-01 00:00:00

abstract：OBJECTIVE:To determine if three different commercially available seizure-detection software packages (Besa 2.0, Encevis 1.7, and Persyst 13) accurately detect seizures with high sensitivity, high specificity, and short detection delay in epilepsy patients undergoing long-term video-electroencephalography (EEG) monitori...

journal_title：Epilepsia

authors： Koren J,Hafner S,Feigl M,Baumgartner C

更新日期：2021-01-19 00:00:00

abstract：OBJECTIVE:To describe the developmental trajectories of quality of life (QoL) in a large cohort of children with epilepsy, and to assess the relative contribution of clinical, psychosocial, and sociodemographic variables on QoL trajectories. METHODS:Five assessments during a 28-month prospective cohort study were used...

journal_title：Epilepsia

authors： Ferro MA,Avery L,Fayed N,Streiner DL,Cunningham CE,Boyle MH,Lach L,Glidden G,Rosenbaum PL,Ronen GM,QUALITÉ group.

更新日期：2017-07-01 00:00:00

abstract：:This paper addresses methodologic issues in studies of mortality, and the impact of these issues in studies of mortality in epilepsy. One important issue is to identify the question: Is it whether epilepsy increases the risk of dying? Or is it whether the underlying condition that led to epilepsy, itself associated wi...

journal_title：Epilepsia

authors： Logroscino G,Hesdorffer DC

更新日期：2005-01-01 00:00:00

abstract：PURPOSE:Childhood epilepsy with occipital paroxysms (CEOP) is characterised by ictal visual hallucinations and occipital epileptiform activity on interictal EEG. A variant has been described with nonvisual symptoms including tonic head and eye deviation, vomiting, and episodes of partial status epilepticus. We fully do...

journal_title：Epilepsia

authors： Ferrie CD,Beaumanoir A,Guerrini R,Kivity S,Vigevano F,Takaishi Y,Watanabe K,Mira L,Capizzi G,Costa P,Valseriati D,Grioni D,Lerman P,Ricci S,Vigliano P,Goumas-Kartalas A,Hashimoto K,Robinson RO,Panayiotopoulos CP

更新日期：1997-03-01 00:00:00

abstract：PURPOSE:The acute, subacute, and chronic effects of vigabatrin (VGB) were studied in patients with refractory complex partial seizures. VGB increases human brain gamma-aminobutyric acid (GABA) and the related metabolites, homocarnosine and 2-pyrrolidinone. METHODS:In vivo measurements of GABA and homocarnosine were ma...

journal_title：Epilepsia

authors： Petroff OA,Hyder F,Collins T,Mattson RH,Rothman DL

更新日期：1999-07-01 00:00:00

abstract：:Seventy-eight patients with temporal lobe type seizures were precisely matched for age, sex, and Wechsler I.Q. levels with patients suffering from other seizure types. Statistically significant differences were established between the groups in regard to treatment response, etiologies, and behavioral variables. Furthe...

journal_title：Epilepsia

authors： Rodin EA,Katz M,Lennox K

更新日期：1976-09-01 00:00:00

abstract：PURPOSE:To characterize features influencing marital status in a group of patients with refractory epilepsy before and after epilepsy surgery and to assess the effect of seizure control on marital status after epilepsy surgery. METHODS:We analyzed marital status in 430 epilepsy surgery patients and in a subset with te...

journal_title：Epilepsia

authors： Carran MA,Kohler CG,O'Connor MJ,Cloud B,Sperling MR

更新日期：1999-12-01 00:00:00

abstract：:The in vitro effects of four antiepileptic drugs (AEDs) on human sperm motility were studied with a transmembrane migration method. Sperm motility of epileptic patients receiving chronic AED therapy was also investigated. Sperm motility was measured immediately after semen had been mixed with AED and after a 2-h prein...

journal_title：Epilepsia

authors： Chen SS,Shen MR,Chen TJ,Lai SL

更新日期：1992-01-01 00:00:00

abstract：:The research literature is consistent in reporting somewhat less familial aggregation in partial than in generalized epilepsy. However, relatives of patients with partial seizures do appear to have higher seizure risks than relatives of controls, suggesting that genetic factors are important in at least some partial e...

journal_title：Epilepsia

authors： Ottman R

更新日期：1989-01-01 00:00:00

abstract：PURPOSE:To evaluate the demographic impact of epilepsy a rural area of Africa. METHODS:A cohort study was conducted between 1991 and 2001 in the Mbam Valley (Cameroon) on two groups of subjects (one of persons with epilepsy, and the other of control individuals matched for sex, age, and village of residence). At the e...

journal_title：Epilepsia

authors： Kamgno J,Pion SD,Boussinesq M

更新日期：2003-07-01 00:00:00

abstract：PURPOSE:Quantitative measurement of hippocampal volume using structural magnetic resonance imaging (MRI) is a valuable tool for detection and lateralization of mesial temporal lobe epilepsy with hippocampal sclerosis (mTLE). We compare two automated hippocampal volume methodologies and manual hippocampal volumetry to d...

journal_title：Epilepsia

authors： Pardoe HR,Pell GS,Abbott DF,Jackson GD

更新日期：2009-12-01 00:00:00