Abstract:
:A 67-year-old woman was admitted to our hospital because of lymphadenopathy and lymphocytosis. Monoclonal integration of HTLV-I provirus DNA was detected, and a diagnosis of adult T-cell leukemia (ATL) was made. Flow cytometry revealed that the ATL cells expressed CD20 as well as T-cell-associated antigens, and expression of CD20 mRNA was also demonstrated. A novel T-cell subpopulation expressing CD20 molecules has recently been identified. This is the first report of CD20-positive ATL, suggesting that HTLV-I can infect and transform CD20-positive T cells.
journal_name
Am J Hematoljournal_title
American journal of hematologyauthors
Yasukawa M,Arai J,Kakimoto M,Sakai I,Kohno H,Fujita Sdoi
10.1002/1096-8652(200101)66:1<39::AID-AJH1005>3.0.keywords:
subject
Has Abstractpub_date
2001-01-01 00:00:00pages
39-41issue
1eissn
0361-8609issn
1096-8652journal_volume
66pub_type
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