当前位置： SCI文献检索 > INTENSIVE CARE MEDICINE期刊下所有文献 > Current management and outcome of tracheobronchial malacia and stenosis presenting to the paediatric intensive care unit.

Current management and outcome of tracheobronchial malacia and stenosis presenting to the paediatric intensive care unit.

Abstract：

OBJECTIVE:To identify factors associated with mortality and prolonged ventilatory requirements in patients admitted to our paediatric intensive care unit (PICU) with tracheobronchial malacia and stenosis diagnosed by dynamic contrast bronchograms. DESIGN:Retrospective review. SETTING:Tertiary paediatric intensive care unit. PATIENTS:Forty-eight cases admitted to our PICU over a 5-year period in whom a diagnosis of tracheobronchial malacia or stenosis was made by dynamic contrast bronchography (1994-1999). INTERVENTIONS:Conservative management, tracheostomy and long-term ventilation, surgical correction, internal or external airway stenting. MEASUREMENTS AND RESULTS:Recording of clinical details, length of invasive ventilation and appearance at contrast bronchography. Five groups of patients were defined: isolated primary airway pathology (n = 7), ex-premature infants (n = 11), vascular rings (n = 9), complex cardiac and/or syndromic pathology (n = 17) and tracheo-oesophageal fistulae (n = 4). The overall mortality was 29%. Median length of invasive ventilation in survivors was 38 days and in patients who died 45. Mortality was highest in the patients with complex cardiac and/or syndromic pathology (p = 0.039 Cox regression analysis) but was not related to any other factor. Patients with stenosis required a significantly longer period of ventilatory support (median length of ventilation 59 days) than patients with malacia (39 days). CONCLUSIONS:Length of ventilation and bronchographic diagnosis did not predict survival. The only factor found to contribute significantly to mortality was the presence of complex cardiac and/or syndromic pathology. However, patients with stenosis required longer ventilatory support than patients with malacia.

journal_name

Intensive Care Med

journal_title

Intensive care medicine

authors

Inwald DP,Roebuck D,Elliott MJ,Mok Q

doi

10.1007/s001340000822

keywords:

subject

Has Abstract

pub_date

2001-04-01 00:00:00

pages

722-9

issue

4

eissn

0342-4642

issn

1432-1238

journal_volume

27

pub_type

杂志文章

相关文献

INTENSIVE CARE MEDICINE文献大全
  • Tigecycline use in critically ill patients: a multicentre prospective observational study in the intensive care setting.

    abstract：PURPOSE:This prospective observational study aimed at describing prescription patterns of tigecycline and patient outcomes in 26 French intensive care units (ICU). METHODS:Data of consecutive cases of adult patients treated with tigecycline were collected from the initiation until 7 days after the end of treatment. Re...

    journal_title：Intensive care medicine

    pub_type： 杂志文章,多中心研究

    doi：10.1007/s00134-014-3323-7

    authors： Montravers P,Dupont H,Bedos JP,Bret P,Tigecycline Group.

    更新日期：2014-07-01 00:00:00

  • Age-dependent effects of gradual decreases in cerebral perfusion pressure on the neurochemical response in swine.

    abstract：OBJECTIVE:There is still a lack of knowledge on the age-dependent relation between a reduction in cerebral perfusion pressure (CPP) and compromised brain perfusion leading to excessive transmitter release and brain damage cascades. The hypothesis is that an age-dependent lower threshold of cerebral blood flow (CBF) aut...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-010-1846-0

    authors： Walter B,Aisenpreis K,Fritz HG,Soukup J,Eiselt M,Bauer R

    更新日期：2010-06-01 00:00:00

  • Frequency of transient streptococcal bacteremia following urgent orotracheal intubation in critically ill patients.

    abstract：OBJECTIVES:To examine whether urgent orotracheal intubation (OI) can induce bacteremia. To find predictive factors for post-intubation bacteremia. DESIGN:Prospective observational study. SETTING:Seventeen-bed medical intensive care unit in a university hospital. PATIENTS:Sixty-eight adult intensive care patients und...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s001340000841

    authors： Rijnders BJ,Wilmer A,Van Eldere J,Van Wijngaerden E

    更新日期：2001-02-01 00:00:00

  • Sonoclot signature during normal pregnancy.

    abstract：OBJECTIVE:The Sonoclot analyser provides global measurement of haemostasis, including plasma coagulation, platelet function and fibrinolysis. Benefits of its use in cardiovascular and hepatic surgery are well-documented and it may be useful in managing obstetric complications. The aim of this study was to determine ran...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s001340050047

    authors： Kjellberg U,Hellgren M

    更新日期：2000-02-01 00:00:00

  • Time course of lung injury in rat acute pancreatitis.

    abstract：OBJECTIVE:Lung injury is a severe complication of acute pancreatitis that increases the mortality rate of the disease. The pathophysiology of acute pancreatitis has been studied in several experimental models, but the kinetics of pulmonary complications in relation to the pancreatic disease is not completely understood...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-006-0264-9

    authors： Morel DR,Frossard JL,Cikirikcioglu B,Tapponnier M,Pastor CM

    更新日期：2006-11-01 00:00:00

  • Theophylline and ethylenediamine pharmacokinetics following administration of aminophylline to septic patients with multiorgan failure.

    abstract：:The pharmacokinetics of theophylline and ethylenediamine were examined in 6 patients with septicaemia and multiorgan failure (MOF). The patients received a bolus injection of 4 mg/kg aminophylline. Aminophylline is the ethylenediamine salt of theophylline. The clearance of theophylline was reduced in all our patients ...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/BF01690768

    authors： Toft P,Heslet L,Hansen M,Klitgaard NA

    更新日期：1991-01-01 00:00:00

  • Colonization and infection in surgical intensive care patients--a prospective study.

    abstract：:Nosocomial infections are a major problem in intensive care patients. Thirty-nine patients, requiring intensive care for 5 days or more (mean 15.8 days) were prospectively investigated, to determine the relation between colonisation and nosocomial infection. Thrice weekly, cultures from the oropharynx, respiratory and...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/BF00255792

    authors： Kerver AJ,Rommes JH,Mevissen-Verhage EA,Hulstaert PF,Vos A,Verhoef J,Wittebol P

    更新日期：1987-01-01 00:00:00

  • In vitro validation of a novel method for continuous intra-abdominal pressure monitoring.

    abstract：OBJECTIVE:Intra-abdominal pressure (IAP) measurement is important in daily clinical practice. Most measurement techniques vary in automaticity and reproducibility. This study tested a new fully automated continuous technique for IAP measurement, the CiMON. METHODS:Three IAP measurement catheters (a Foley manometer and...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-007-0952-0

    authors： Malbrain ML,De laet I,Viaene D,Schoonheydt K,Dits H

    更新日期：2008-04-01 00:00:00

  • Evolution of pattern of breathing during a spontaneous breathing trial predicts successful extubation.

    abstract：PURPOSE:Rapid shallow breathing may occur at any time during spontaneous breathing trials (SBT), questioning the utility of a single determination of the rapid shallow breathing index (RSBI). We hypothesize that change in RSBI during SBT may more accurately predict successful extubation than a single determination. ME...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-009-1735-6

    authors： Segal LN,Oei E,Oppenheimer BW,Goldring RM,Bustami RT,Ruggiero S,Berger KI,Fiel SB

    更新日期：2010-03-01 00:00:00

  • Apoptosis inhibition in P. aeruginosa-induced lung injury influences lung fluid balance.

    abstract：OBJECTIVE:Pseudomonas aeruginosa-induced lung injury is characterized not only by the alteration in lung fluid movement but also by apoptosis of lung epithelial and endothelial cells. We studied whether inhibition of apoptosis using a broad spectrum caspase inhibitor, benzyloxycarbonyl-Val-Ala-Asp fluoromethylketone (Z...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-004-2165-0

    authors： Le Berre R,Faure K,Fauvel H,Viget NB,Ader F,Prangère T,Thomas AM,Leroy X,Pittet JF,Marchetti P,Guery BP

    更新日期：2004-06-01 00:00:00

  • Variability of splanchnic blood flow in patients with sepsis.

    abstract：OBJECTIVES:Previous studies on therapeutic interventions in sepsis have assumed stability of the measure of splanchnic blood flow throughout the study. We assessed the variability of splanchnic blood flow during stable global hemodynamics in eight patients with sepsis requiring treatment with dobutamine and/or norepine...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s001340100980

    authors： Sakka SG,Reinhart K,Wegscheider K,Meier-Hellmann A

    更新日期：2001-08-01 00:00:00

  • Inter-observer variability in APACHE II scoring: effect of strict guidelines and training.

    abstract：OBJECTIVE:To assess the effect of strict guidelines and a rigorous training program on variability in scoring the revised Acute Physiology and Chronic Health Evaluation (APACHE II). DESIGN AND SETTING:Prospective survey and intervention in the surgical ICU of a university teaching hospital. MEASUREMENTS:Seven experie...

    journal_title：Intensive care medicine

    pub_type： 临床试验,杂志文章

    doi：10.1007/s001340101012

    authors： Polderman KH,Jorna EM,Girbes AR

    更新日期：2001-08-01 00:00:00

  • High-dose intravenous magnesium sulfate in the management of life-threatening status asthmaticus.

    abstract：:In severe status asthmaticus basic medical treatment often fails to improve the patient's condition. Mechanical ventilation in this situation is associated with a high incidence of serious complications. After the bronchodilating effect of moderate-dose magnesium sulfate in asthmatic patients had been demonstrated in ...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/BF01711089

    authors： Sydow M,Crozier TA,Zielmann S,Radke J,Burchardi H

    更新日期：1993-01-01 00:00:00

  • Short-term evaluation of sedation with sevoflurane administered by the anesthetic conserving device in critically ill patients.

    abstract：PURPOSE:Assessing feasibility and physiological effects of sedation with sevoflurane, administered with the anesthetic conserving device (AnaConDa), in comparison with propofol and remifentanil. METHODS:Seventeen patients undergoing mechanical ventilation underwent sedation with sevoflurane delivered with AnaConDa (ph...

    journal_title：Intensive care medicine

    pub_type： 临床试验,杂志文章

    doi：10.1007/s00134-009-1414-7

    authors： Migliari M,Bellani G,Rona R,Isgrò S,Vergnano B,Mauri T,Patroniti N,Pesenti A,Foti G

    更新日期：2009-07-01 00:00:00

  • Regional distribution of gas and tissue in acute respiratory distress syndrome. II. Physiological correlations and definition of an ARDS Severity Score. CT Scan ARDS Study Group.

    abstract：OBJECTIVES:(a) To assess whether differences in lung morphology observed in patients with adult respiratory distress syndrome (ARDS) are associated with differences in cardiorespiratory parameters, lung mechanics, and outcome. (b) To propose a new ARDS Severity Score to identify patients with a high mortality risk. DE...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s001340051317

    authors： Rouby JJ,Puybasset L,Cluzel P,Richecoeur J,Lu Q,Grenier P

    更新日期：2000-08-01 00:00:00

  • Audit of intensive care: a 30 month experience using the Apache II severity of disease classification system.

    abstract：:608 patients admitted to a general Intensive Care Unit (ICU) over a 30 month period were analyzed according to the Apache II Severity of Disease Classification System on day one of admission. Hospital outcome details were available on 583 patients in the series. The mean Apache II scores for survivors (396) and non-su...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/BF00263531

    authors： Jacobs S,Chang RW,Lee B,Lee B

    更新日期：1988-01-01 00:00:00

  • Evaluation of a simple method for minimizing iatrogenic blood loss from discard volumes in critically ill newborns and children.

    abstract：OBJECTIVE:To validate a simple method avoiding discard volumes in pediatric patients with indwelling arterial and venous lines. DESIGN:Zero-discarding was achieved by passive extracorporeal arteriovenous backflow via standard single pressure transducer equipment. We tested backflow distances (10, 20 and 30 cm beyond t...

    journal_title：Intensive care medicine

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1007/s001340100951

    authors： Weiss M,Fischer J,Boeckmann M,Rohrer B,Baenziger O

    更新日期：2001-06-01 00:00:00

  • Hydrostatic mechanisms may contribute to the pathogenesis of human re-expansion pulmonary edema.

    abstract：OBJECTIVE:The primary objective was to test the hypothesis that clinical re-expansion pulmonary edema is predominantly due to increased permeability of the alveolar-capillary barrier. A secondary objective was to determine if the alveolar epithelium was functionally intact in patients with re-expansion pulmonary edema ...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-004-2379-1

    authors： Sue RD,Matthay MA,Ware LB

    更新日期：2004-10-01 00:00:00

  • Risk of Clostridium difficile diarrhoea in critically ill patients treated with erythromycin-based prokinetic therapy for feed intolerance.

    abstract：OBJECTIVE:To determine the incidence of Clostridium difficile (CD) diarrhoea in feed-intolerant, critically ill patients who received erythromycin-based prokinetic therapy. DESIGN AND SETTING:Prospective observational study in a mixed intensive care unit. METHODS:The development of diarrhoea (> 3 loose, liquid stool ...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-007-0834-5

    authors： Nguyen NQ,Ching K,Fraser RJ,Chapman MJ,Holloway RH

    更新日期：2008-01-01 00:00:00

  • Regional variation in critical care provision and outcome after high-risk surgery.

    abstract：PURPOSE:Evidence of variation in mortality after surgery may indicate preventable postoperative death. We sought to determine if regional differences in outcome were present in surgical patients admitted to critical care in the UK. METHODS:We extracted data on admission characteristics, case mix and outcome of all pat...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-015-3980-1

    authors： Gillies MA,Power GS,Harrison DA,Fleming A,Cook B,Walsh TS,Pearse RM,Rowan KM

    更新日期：2015-10-01 00:00:00

  • Inspiratory flow effects on mechanically ventilated patients: lung volume, inhomogeneity, and arterial oxygenation.

    abstract：:Changes in the inspiratory flow rate of mechanically ventilated patients can affect arterial oxygenation. Although the mechanism producing this alteration is not certain, one possible mechanism is a change in ventilation inhomogeneity. This study was performed to determine if the inspiratory flow setting would affect ...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/BF00254316

    authors： Felton CR,Montenegro HD,Saidel GM

    更新日期：1984-01-01 00:00:00

  • Delayed cerebral thrombosis in bacterial meningitis: a prospective cohort study.

    abstract：PURPOSE:To study the incidence and clinical characteristics of delayed cerebral thrombosis in bacterial meningitis patients. METHODS:We assessed the incidence and clinical characteristics of delayed cerebral thrombosis in adults with cerebrospinal fluid (CSF) culture-proven community-acquired bacterial meningitis incl...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-012-2792-9

    authors： Lucas MJ,Brouwer MC,van de Beek D

    更新日期：2013-05-01 00:00:00

  • Nasal, pulmonary and autoinhaled nitric oxide at rest and during moderate exercise.

    abstract：OBJECTIVE:To investigate nasal nitric oxide (NO) excretion, pulmonary NO excretion, and autoinhalation of nasally released NO at rest compared with that during moderate exercise in smokers and non-smokers. DESIGN:Prospective observational study. SETTING:University laboratory. PARTICIPANTS:Fourteen healthy adult volu...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s001340051172

    authors： Busch T,Kuhlen R,Knorr M,Kelly K,Lewandowski K,Rossaint R,Falke KJ,Gerlach H

    更新日期：2000-04-01 00:00:00

  • Evaluation of severity scoring systems in ICUs--translation, conversion and definition ambiguities as a source of inter-observer variability in Apache II, SAPS and OSF.

    abstract：OBJECTIVE:To explore translation, conversion and definition ambiguities, when using severity scoring systems in patients admitted to intensive care units (ICUs). DESIGN:A prospective study of the prognosis of acute renal failure in ICUs. SETTING:The study was conducted in 20 French ICUs. PATIENTS:360 patients presen...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/BF01705416

    authors： Féry-Lemonnier E,Landais P,Loirat P,Kleinknecht D,Brivet F

    更新日期：1995-04-01 00:00:00

  • Biomarkers for prediction of renal replacement therapy in acute kidney injury: a systematic review and meta-analysis.

    abstract：PURPOSE:Acute kidney injury (AKI) frequently occurs in critically ill patients and often precipitates use of renal replacement therapy (RRT). However, the ideal circumstances for whether and when to start RRT remain unclear. We performed evidence synthesis of the available literature to evaluate the value of biomarkers...

    journal_title：Intensive care medicine

    pub_type： 杂志文章,评审

    doi：10.1007/s00134-018-5126-8

    authors： Klein SJ,Brandtner AK,Lehner GF,Ulmer H,Bagshaw SM,Wiedermann CJ,Joannidis M

    更新日期：2018-03-01 00:00:00

  • Correction to: Impact on mortality of prompt admission to critical care for deteriorating ward patients: an instrumental variable analysis using critical care bed strain.

    abstract：:This article was originally published under a CC BY-NC 4.0 license, but has now been made available under a CC BY 4.0 license. The PDF and HTML versions of the paper have been modified accordingly. ...

    journal_title：Intensive care medicine

    pub_type： 杂志文章,已发布勘误

    doi：10.1007/s00134-018-5254-1

    authors： Harris S,Singer M,Sanderson C,Grieve R,Harrison D,Rowan K

    更新日期：2018-05-01 00:00:00

  • Effects of alveolar recruitment maneuvers on clinical outcomes in patients with acute respiratory distress syndrome: a systematic review and meta-analysis.

    abstract：PURPOSE:To assess the effects of alveolar recruitment maneuvers (ARMs) on clinical outcomes in patients with acute respiratory distress syndrome (ARDS). METHODS:We conducted a search of the MEDLINE, EMBASE, LILACS, CINAHL, CENTRAL, Scopus, and Web of Science (from inception to July 2014) databases for all (i.e. no lan...

    journal_title：Intensive care medicine

    pub_type： 杂志文章,meta分析,评审

    doi：10.1007/s00134-014-3413-6

    authors： Suzumura EA,Figueiró M,Normilio-Silva K,Laranjeira L,Oliveira C,Buehler AM,Bugano D,Passos Amato MB,Ribeiro Carvalho CR,Berwanger O,Cavalcanti AB

    更新日期：2014-09-01 00:00:00

  • Craniectomy in severe, life-threatening encephalitis: a report on outcome and long-term prognosis of four cases.

    abstract：OBJECTIVE:To report the feasibility of craniectomy with duraplasty in four patients with life-threatening encephalitis and, in particular, their long-term outcome. DESIGN:Report of four cases, analysis of the acute clinical course and neurological long-term sequelae. RESULTS:Generous craniectomy with duraplasty was p...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s001340101027

    authors： Taferner E,Pfausler B,Kofler A,Spiss H,Engelhardt K,Kampfl A,Schmutzhard E

    更新日期：2001-08-01 00:00:00

  • Long-term evaluation of granulocyte-colony stimulating factor on hypoxic-ischemic brain damage in infant rats.

    abstract：PURPOSE:Hypoxia-ischemia (HI), as a major cause of fetal brain damage, has long-lasting neurological implications. Therefore, therapeutic interventions that attenuate the neuropathological outcome of HI while also improving the neurofunctional outcome are of paramount clinical importance. The aim of this study was to i...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-010-1913-6

    authors： Fathali N,Lekic T,Zhang JH,Tang J

    更新日期：2010-09-01 00:00:00

  • Trends in sedation practices in Danish intensive care units in 2003: a national survey.

    abstract：OBJECTIVE:The aim of the study was to explore trends and changes in sedation practices for mechanically ventilated patients in Danish intensive care units (ICUs) and to compare sedation practices in 1997 and 2003. DESIGN:The study was a follow-up survey with a descriptive and comparative cross-sectional multicenter de...

    journal_title：Intensive care medicine

    pub_type： 杂志文章,多中心研究

    doi：10.1007/s00134-005-2856-1

    authors： Egerod I,Christensen BV,Johansen L

    更新日期：2006-01-01 00:00:00