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Inspiratory flow effects on mechanically ventilated patients: lung volume, inhomogeneity, and arterial oxygenation.

Abstract：

:Changes in the inspiratory flow rate of mechanically ventilated patients can affect arterial oxygenation. Although the mechanism producing this alteration is not certain, one possible mechanism is a change in ventilation inhomogeneity. This study was performed to determine if the inspiratory flow setting would affect ventilation inhomogeneity in patients who have minimal or no lung disease, but who require mechanical ventilation after cardiopulmonary bypass surgery. When inspiratory flows were doubled, PaO2 increased and FRC fell. However, no associated change in ventilation inhomogeneity was detected. It is concluded that inspiratory flow rate can affect arterial oxygenation of subjects without severe obstructive pulmonary disease through mechanisms other than altering ventilation inhomogeneity, such as changes in cardiac output or in distribution of perfusion.

journal_name

Intensive Care Med

journal_title

Intensive care medicine

authors

Felton CR,Montenegro HD,Saidel GM

doi

10.1007/BF00254316

subject

Has Abstract

pub_date

1984-01-01 00:00:00

pages

281-6

issue

6

eissn

0342-4642

issn

1432-1238

journal_volume

10

pub_type

杂志文章

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