Abstract：
:We explored the effects of sensory information upon procedural learning using three versions of the serial reaction-time task (SRTT): a standard task where the position of the stimulus cued the response; a non-standard task where the color of the stimulus was related to the correct response; and a combined task where both the color and position simultaneously cued the response. Despite these differences, each task had the same temporal pattern of a repeating ten-item sequence. We refer to each of these tasks based upon the cues available for guiding learning: position, color, and combined tasks. Procedural sequence learning was greater for the combined than for the other two tasks, suggesting that learning is enhanced when multiple sources of sensory information cue consistently and simultaneously for the same response. Transfer of skill occurred across all the tasks, except from the position to the color task. These results suggest that a fundamental neural algorithm is responsible for acquiring knowledge about a temporal sequence of responses rather than forming an associative relationship amongst stimuli.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Robertson EM,Pascual-Leone Adoi
10.1007/s002210000673keywords:
subject
Has Abstractpub_date
2001-04-01 00:00:00pages
336-45issue
3-4eissn
0014-4819issn
1432-1106journal_volume
137pub_type
临床试验,杂志文章,随机对照试验abstract：:There is still controversy in the literature whether a single episode of mild traumatic brain injury (MTBI) results in short-term functional and/or structural deficits as well as any induced long-term residual effects. With the inability of traditional structural brain imaging techniques to accurately diagnosis MTBI, ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-010-2294-3
更新日期：2010-07-01 00:00:00
abstract：:The effects of visual contextual illusions on motor behaviour vary largely between experimental conditions. Whereas it has often been reported that the effects of illusions on pointing and grasping are largest when the movement is performed some time after the stimulus has disappeared, the effect of a delay has hardly...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-015-4520-5
更新日期：2016-04-01 00:00:00
abstract：:Transcranial direct current stimulation (tDCS) induces cortical excitability changes in animals and humans that can last beyond the duration of stimulation. Preliminary evidence suggests that tDCS may have an analgesic effect; however, the timing of these effects, especially when associated with consecutive sessions o...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-012-3149-x
更新日期：2012-08-01 00:00:00
abstract：:Several recent studies indicate that saccades elicited in the absence of a visual target are slower than visually-guided movements of the same size. In addition, we have shown earlier that the slower saccades observed in two different paradigms had more asymmetrical (skewed) velocity profiles. Recently, it has been re...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00253624
更新日期：1989-01-01 00:00:00
abstract：:The purpose of the study was to determine the contributions of endpoint variance and trajectory variability to the endpoint accuracy of goal-directed isometric contractions when the target force and contraction speed were varied. Thirteen young adults (25 +/- 6 years) performed blocks of 15 trials at each of 2 contrac...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-009-2126-5
更新日期：2010-04-01 00:00:00
abstract：:Cultured rat hippocampal neurons with short processes were investigated using the whole cell voltage clamp under conditions appropriate for isolating Na+ currents. After incubation of the neuron culture for a period of 15-30 min in 1 mM sodium valproate, several parameters of the Na+ current were changed. The peak Na+...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00228395
更新日期：1993-01-01 00:00:00
abstract：:Previous investigations have suggested that the dorsolateral pontine tegmentum (DLP) may be part of a system essential for classical conditioning of the nictitating membrane response. The present study examined CR-related firing patterns of extracellularly-recorded single units in the DLP. Differential conditioning, u...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00243830
更新日期：1986-01-01 00:00:00
abstract：:Spike trains of long duration were recorded from concurrently active pairs of motor units in the human masseter and tibialis anterior muscles. An innovative analysis technique was used to investigate functional coupling between the motoneurons by plotting the discharge frequency of one motor unit with respect to the f...
journal_title：Experimental brain research
pub_type： 临床试验,杂志文章
doi：10.1007/BF00228735
更新日期：1996-10-01 00:00:00
abstract：:Postural equilibrium is known to be controlled by sensorimotor reflexes and automatic control loops but also depends on high-level body representation in space, probably implicating the right temporoparietal cortex. Indeed, short-term prism adaptation to a 10 degrees rightward visual shift has been shown to reduce pre...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-002-1294-3
更新日期：2003-01-01 00:00:00
abstract：:The tuberomammillary nucleus (TM) located in the posterior part of the hypothalamus is the main source of neuronal histamine in the central nervous system. Recent work from our laboratories has indicated an involvement of the TM region in neuronal plasticity and reinforcement processes. In the present study, we invest...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210050301
更新日期：1998-02-01 00:00:00
abstract：:The responses of 192 single units in the cat's pulvinar-complex, comprising the inferior, medial and lateral pulvinar nuclei, were studied in paralysed cats, lightly anaesthetized with N2O/O2 supplemented with pentobarbitone. About 60% of the cells were visually driven and their receptive fields classified as either d...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00235804
更新日期：1978-01-18 00:00:00
abstract：:We examine cross-modality commonalities in visual and auditory imageries during fMRI scanning in a sample of healthy young adults. In a visual task combining viewed and imagined stimuli, 28 participants were asked to imagine novel scenes related to the other images, and in a similar auditory task combining heard and i...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-019-05492-4
更新日期：2019-05-01 00:00:00
abstract：:The presence of after-effects in adaptation tasks implies that an existing internal model has been updated. Previously, we showed that although observers adapted to a visuomotor perturbation, they did not show after-effects. In this experiment, we tested 2 further observer groups and an actor group. Observers were now...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-011-2996-1
更新日期：2012-04-01 00:00:00
abstract：:The aim of the study was to define the spike threshold changes in motoneurons during naturally evoked activation. Spike activity was evoked in the gastrocnemius-soleus motoneurons of decerebrate cats by controlled stretches of the homonymous muscles. The spike thresholds were defined by using the first derivative of t...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-010-2285-4
更新日期：2010-06-01 00:00:00
abstract：:In the lateral septal area (LSA), both inhibitory and excitatory dopamine (DA) actions, as well as hypothalamic and midbrain DA efferents, have been described. Some neurons of the hypothalamic and midbrain DA systems contain somatostatin (SOM) or neurotensin (NT), and, in the LSA, the distribution of fibers containing...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00229030
更新日期：1993-01-01 00:00:00
abstract：:A force-matching task was used to study the influence of constraining tactile information from the hand on the perception of forces generated with the index finger flexors, the palmar prehensile grasp and with the elbow flexors. Subjects generated the same reference forces (2-10 N) with each muscle group and matched t...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-005-0259-8
更新日期：2006-01-01 00:00:00
abstract：:The present study examined the kinematics of unrestricted reaches to prismatically-displaced targets. The kinematic analysis allowed us (1) to document how and where in the reach adjustments were made to compensate for the prismatic displacement. (2) to detail the changes that occur in the characteristics of reaches d...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00230245
更新日期：1989-01-01 00:00:00
abstract：:The evidence on the impact of subthalamic nucleus deep brain stimulation (STN-DBS) on action restraint on Go/NoGO reaction time (RT) tasks in Parkinson's disease (PD) is inconsistent; with some studies reporting no effect and others finding that STN stimulation interferes with withholding of responses and results in m...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-015-4531-2
更新日期：2016-04-01 00:00:00
abstract：:An experiment using reciprocal arm and wrist aiming movements with an amplitude of 16(o) and target width of .5° (ID = 6) was conducted to determine the impact of adding external loads. We predicted that wrist and arm performance may be differentially impacted by the added mass. Participants were asked to flex/extend ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-012-3303-5
更新日期：2013-01-01 00:00:00
abstract：:The neuronal responsiveness to three-dimensional (3D) motion in cat posteromedial lateral suprasylvian (PMLS) cortex was studied using a computer-controlled, stereoscopic 3D graphic display capable of reproducing the major visual cues for natural 3D motion, including motion disparity, size, texture, and shading change...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210050509
更新日期：1998-09-01 00:00:00
abstract：:Human gait is a complex process in the central nervous system that results from the integrity of various mechanisms, including different cortical and subcortical structures. In the present study, we investigated cortical activity during lower limb movement using EEG. Assisted by a dynamic tilt table, all subjects perf...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-010-2223-5
更新日期：2010-05-01 00:00:00
abstract：:Inter-limb learning transfer (ILT) between the upper-limbs has been well documented, but no corresponding study of the lower limbs has been done. We investigated ILT in the lower limbs of subjects who learned to move a cursor toward targets within 800 ms using ankle movements: plantar/dorsi-flexion and inversion/evers...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-008-1547-x
更新日期：2009-01-01 00:00:00
abstract：:Activation of glial cells has been proposed to contribute to neuronal dysfunction and neuronal cell death in Alzheimer's disease. In this study, we attempt to determine some of the effects of secreted factors from activated murine N-11 microglia on viability and morphology of neurons using the differentiated neuroblas...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-003-1389-5
更新日期：2003-05-01 00:00:00
abstract：:Local alpha-band synchronization has been associated with both cortical idling and active inhibition. Recent evidence, however, suggests that long-range alpha synchronization increases functional coupling between cortical regions. We demonstrate increased long-range alpha and beta band phase synchronization during sho...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-009-2086-9
更新日期：2010-04-01 00:00:00
abstract：:Extracellular unit recording was employed to study the axonal properties and efferent projections of antidromically identified neurons in the olfactory peduncle (OP) region of a primitive eutherian macrosmatic mammal, the south american armadillo (Chaetophractus vellerosus). Of 72 cells which satisfied the criteria fo...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00340490
更新日期：1986-01-01 00:00:00
abstract：:When sight-reading a piece of music the eyes constantly scan the score slightly ahead of music execution. This separation between reading and acting is commonly termed eye-hand span and can be expressed in two ways: as anticipation in notes or in time. Previous research, predominantly in piano players, found skill-dep...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-009-1719-3
更新日期：2009-04-01 00:00:00
abstract：:In rats under alpha-chloralose or without general anesthesia the effect of a lateral olfactory tract stimulus on the caudate nucleus electric activity was explored by bipolar macroelectrodes. The stimulation effectiveness and the reactivity of recording sites to somatic stimuli were systematically tested. Under these ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00237049
更新日期：1977-08-31 00:00:00
abstract：:Preshaping the digits and orienting the hand when reaching to grasp a distal target is proposed to be optimal when guided by vision. A reach-to-grasp movement to an object in one's own mouth is a natural and commonly used movement, but there has been no previous description of how it is performed. The movement require...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-012-3164-y
更新日期：2012-08-01 00:00:00
abstract：:The desire to increase rewards and minimize punishing events is a powerful driver in behaviour. Here, we assess how the value of a location affects subsequent deployment of goal-directed attention as well as involuntary capture of attention on a trial-to-trial basis. By tracking eye position, we investigated whether t...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-013-3654-6
更新日期：2013-10-01 00:00:00
abstract：:Previous studies have demonstrated changes in motor memories with the passage of time on the order of hours. We sought to further this work by determining the influence that time on the order of seconds has on motor learning by changing the duration between successive reaches (inter-reach-interval (IRI)). Human subjec...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-005-0062-6
更新日期：2005-11-01 00:00:00
