Cobas Mira S endpoint enzymatic assay for plasma formate.

abstract：:This report describes a possible suicide by overdosage with diltiazem. The decreased, a 39-year-old male who had been under treatment for an unidentified heart condition, was discovered on the bathroom floor in his residence. Comprehensive drug screens performed on available postmortem specimens revealed the presence ...

journal_title：Journal of analytical toxicology

authors： Kalin JR,Wood KM,Lee AJ

更新日期：1994-05-01 00:00:00

abstract：:A sensitive and specific method was developed for the quantitative analysis of l-alpha-acetylmethadol (LAAM), l-alpha-acetyl-N-normethadol (norLAAM), and l-alpha-acetyl-N,N-dinormethadol (dinorLAAM) in hair. In the development of this method, it was determined that sample pretreatment methods performed by the laborato...

journal_title：Journal of analytical toxicology

authors： Wilkins DG,Valdez AS,Krueger GG,Rollins DE

更新日期：1997-10-01 00:00:00

abstract：:The retention index system is a reproducible means for the identification of drugs in toxicology samples analyzed by gas chromatography with flame ionization detectors. Nitrogen-phosphorus (NP) detectors do not respond well to the standard n-alkanes, which lack nitrogen and phosphorus groups and which are used to obta...

journal_title：Journal of analytical toxicology

authors： Watts VW,Simonick TF

更新日期：1987-09-01 00:00:00

abstract：:As an approved medicinal product and reportedly an abused substance that have been associated with death and "considered to be a factor...of impaired driving, sexual assault, and other violent crimes", triazolam is controlled at the same level (Level III) as flunitrazepam in Taiwan. Alleged misuses of this substance h...

journal_title：Journal of analytical toxicology

authors： Lin DL,Huang TY,Liu HC,Yin RM

更新日期：2005-03-01 00:00:00

abstract：:Metabolic transformation of zearalenone (ZEA), a mycotoxin which can contaminate both food and feed, results in the formation of five metabolites, one of them being zeranol (α-ZAL), which can be abused in farm animals as a growth promoter. To the best of our knowledge, there is no analytical method that can distinguis...

journal_title：Journal of analytical toxicology

authors： Vulić A,Lešić T,Kudumija N,Mikuš T,Pleadin J

更新日期：2019-03-01 00:00:00

abstract：:Vitreous humor is a potential alternative matrix for postmortem toxicology drug screens when peripheral blood is unavailable. It is easily and reliably collected and may not suffer from the same postmortem redistribution as seen in blood. Here, we compared the concentrations of 7 acidic drugs (acetaminophen, ibuprofen...

journal_title：Journal of analytical toxicology

authors： Hubbard JA,Navarrete AL,Fitzgerald RL,McIntyre IM

更新日期：2019-11-06 00:00:00

abstract：:The quantity of thiocyanate ion in vegetables has been determined due to its relationship with endemic goiter. The technique is based on the use of gas chromatography with electron capture detection (ECD), which provides good sensitivities. ...

journal_title：Journal of analytical toxicology

authors： Olea Serrano MR,Ruiz Lopez MD,Justica Palomares H

更新日期：1988-11-01 00:00:00

abstract：:Synthetic cathinones inhibit monoamine transporters, such as serotonin, norepinephrine, and dopamine transporters, and act on the central nervous system via increasing synaptic concentrations of monoamines. These compounds, which are highly addictive and potentially poisonous, are new psychoactive substances. In this ...

journal_title：Journal of analytical toxicology

authors： Fujita Y,Mita T,Usui K,Kamijo Y,Kikuchi S,Onodera M,Fujino Y,Inoue Y

更新日期：2018-01-01 00:00:00

abstract：:A modification of the Syva EMIT-tox Serum Barbiturate Assay was developed to provide a rapid and practical method for quantitating serum barbiturates. Standard curves for eight selected barbiturates were run using specific sets of standards for each. Correlation coefficients, slopes, and y-intercepts for the curves of...

journal_title：Journal of analytical toxicology

authors： Watson AT,Manno JE,Manno BR

更新日期：1983-11-01 00:00:00

abstract：:The purpose of this study was to develop and validate a gas chromatography-mass spectrometry method to detect drugs of abuse in a single sample of tooth. Pulverized samples of dental materials were subjected to acid hydrolysis to detect opiates, cocaine and their metabolites. The residual dental materials from these a...

journal_title：Journal of analytical toxicology

authors： Ottaviani G,Cameriere R,Cippitelli M,Froldi R,Tassoni G,Zampi M,Cingolani M

更新日期：2017-01-01 00:00:00

abstract：:The gelsemium plants are highly poisonous but toxicological evaluation of suspected poisoning cases has been hampered by the chemical complexity of the gelsemium toxins involved. A novel liquid chromatography-tandem mass spectrometry protocol was optimized for the collective detection of gelsemine and related alkaloid...

journal_title：Journal of analytical toxicology

authors： Lai CK,Chan YW

更新日期：2009-01-01 00:00:00

abstract：:The U.S. Drug Enforcement Administration has several different systems for collecting information on drugs of abuse. One is an early warning system, which collects information to provide scientific data and interpretation on drug abuse. Another is the collection of data from evidence submitted to DEA laboratories. Thi...

journal_title：Journal of analytical toxicology

authors： Frank RS

更新日期：1987-11-01 00:00:00

abstract：:A rapid and simple liquid chromatography tandem mass spectrometry method was developed and validated for the simultaneous determination of L-ephedrine, pseudoephedrine, and caffeine in male Fisher-344 rat plasma at nanogram-per-milliliter concentrations for use in support of toxicology studies. Only 25 μL of plasma is...

journal_title：Journal of analytical toxicology

authors： Cooper SD,Fletcher BL,Silinski MA,Brown SS,Lodge JW,Fernando RA,Collins BJ

更新日期：2011-07-01 00:00:00

abstract：:We report the validation of a quantitative method for paraquat in plasma and urine using high-performance liquid chromatography (HPLC) with ultraviolet detection (260 nm). Furthermore, we illustrate the use of this method in the clinic (over five years), in conjunction with a qualitative urine paraquat screen. Urine o...

journal_title：Journal of analytical toxicology

authors： Taylor PJ,Salm P,Pillans PI

更新日期：2001-09-01 00:00:00

abstract：:Draft guidelines for the use of oral fluid for workplace drug testing are under development by the Substance Abuse and Mental Health Services Administration (SAMHSA) in cooperation with industry and researchers. Comparison studies of the effectiveness of oral fluid testing versus urine testing are needed to establish ...

journal_title：Journal of analytical toxicology

authors： Cone EJ,Presley L,Lehrer M,Seiter W,Smith M,Kardos KW,Fritch D,Salamone S,Niedbala RS

更新日期：2002-11-01 00:00:00

abstract：:Caffeine is the most widely consumed drug in the world with coffee representing a major source of intake. Despite widespread availability, various medical conditions necessitate caffeine-restricted diets. Patients on certain prescription medications are advised to discontinue caffeine intake. Such admonition has impli...

journal_title：Journal of analytical toxicology

authors： McCusker RR,Fuehrlein B,Goldberger BA,Gold MS,Cone EJ

更新日期：2006-10-01 00:00:00

abstract：:Exemplars of current commercial breath-alcohol simulators were studied to ascertain their suitability for control tests and as calibrators in breath-alcohol analysis. Temperature, effluent volumes and pressures, effluent-alcohol concentration, and alcohol depletion were measured for simulators coupled with various cur...

journal_title：Journal of analytical toxicology

authors： Dubowski KM,Essary NA

更新日期：1991-09-01 00:00:00

abstract：:Human urine was tested for tricyclic antidepressants with fluorescence polarization immunoassay (FPIA) reagents on Abbott's ADx system and with EIA reagents on Syva's ETS system. A 75-ng/mL imipramine calibrator cutoff was used with the ADx system and a 300-ng/mL nortriptyline calibrator cutoff with the ETS system. Th...

journal_title：Journal of analytical toxicology

authors： Meenan GM,Barlotta S,Lehrer M

更新日期：1990-09-01 00:00:00

abstract：:The List of Prohibited Substances and Methods (the List), an International Standard published yearly by the World Anti-Doping Agency (WADA), determines which substances and methods are prohibited in sport in- and out-of-competition. Stimulants are included within drug class S.6 under the in-competition testing sectio...

journal_title：Journal of analytical toxicology

authors： Boghosian T,Mazzoni I,Barroso O,Rabin O

更新日期：2011-11-01 00:00:00

abstract：:A case report involving a 34-year-old white male who was found dead at home by his roommate is presented. At the time of his death, he was being treated with tramadol/acetaminophen, metaxalone, oxycodone, and amitriptyline. The decedent's mother stated that he had been taking increasing amounts of pain medication in o...

journal_title：Journal of analytical toxicology

authors： Bynum ND,Poklis JL,Gaffney-Kraft M,Garside D,Ropero-Miller JD

更新日期：2005-07-01 00:00:00

abstract：:A rapid, sensitive, and specific method for the determination of opiates and cocaine and metabolites in urine, plasma, and blood was established. A one-step extraction followed by liquid chromatography-electrospray ionization tandem mass spectrometry operating in multiple reaction monitoring mode was used. Two chromat...

journal_title：Journal of analytical toxicology

authors： Cailleux A,Le Bouil A,Auger B,Bonsergent G,Turcant A,Allain P

更新日期：1999-11-01 00:00:00

abstract：:Postmortem findings are presented for fourteen cases of Verapamil induced or related deaths. Liver, blood, and stomach concentrations of Verapamil alone or in combination with alcohol or other drugs are given with the age and sex of each victim and with the coroner's findings. The significance of these levels is discu...

journal_title：Journal of analytical toxicology

authors： Chan LF,Chhuy LH,Crowley RJ

更新日期：1987-07-01 00:00:00

abstract：:Synthetic cannabinoids emerged on the designer drug market in recent years due to their ability to produce cannabis-like effects without the risk of detection by traditional drug testing techniques such as immunoassay and gas chromatography-mass spectrometry. As government agencies work to schedule existing synthetic ...

journal_title：Journal of analytical toxicology

authors： Knittel JL,Holler JM,Chmiel JD,Vorce SP,Magluilo J Jr,Levine B,Ramos G,Bosy TZ

更新日期：2016-04-01 00:00:00

abstract：:A quantitative gas chromatographic assay for the determination of phenelzine in plasma or other fluids is presented. A stable derivative is formed by cyclization with acetylacetone, and the derivative is separated, purified, and concentrated by liquid-liquid solvent extraction. Analysis of the extracts is by capillary...

journal_title：Journal of analytical toxicology

authors： Lichtenwalner M,McMullin M,Hardy D,Rieders F

更新日期：1988-03-01 00:00:00

abstract：:A rapid, specific and quantitative high-performance liquid chromatography assay procedure is described for the determination of ICI 125, 211, (I), a guanidino-thiazole H2-receptor antagonist, in small samples of animal plasma. A 0.2 mL aliquot of plasma is extracted at pH 9 with ethyl acetate. After reconstitution in ...

journal_title：Journal of analytical toxicology

authors： Monson K,Simon RK,Malbica JO

更新日期：1980-09-01 00:00:00

abstract：:Calibration model selection is required for all quantitative methods in toxicology and more broadly in bioanalysis. This typically involves selecting the equation order (quadratic or linear) and weighting factor correctly modelizing the data. A mis-selection of the calibration model will generate lower quality control...

journal_title：Journal of analytical toxicology

authors： Desharnais B,Camirand-Lemyre F,Mireault P,Skinner CD

更新日期：2017-05-01 00:00:00

abstract：:A method for the simultaneous analysis of cocaine (COC), derivatized benzoylecgonine (BE), and derivatized ecgonine methyl ester (EME) has been developed. Blood or urine containing deuterated analogs of the three analytes is extracted by pouring over a Chem-Elut column and eluting with chloroform/isopropanol (9:1). Th...

journal_title：Journal of analytical toxicology

authors： Isenschmid DS,Levine BS,Caplan YH

更新日期：1988-09-01 00:00:00

abstract：:Oral fluid (OF) is increasingly used for clinical, forensic and workplace drug testing as an alternative to urine. Uncertainties surrounding OF collection device performance, drug stability and testing reproducibility may be partially responsible for delays in the implementation of OF testing in regulated drug testing...

journal_title：Journal of analytical toxicology

authors： Samano KL,Anne L,Johnson T,Tang K,Sample RH

更新日期：2015-10-01 00:00:00

abstract：:Methoxyacetylfentanyl and cyclopropylfentanyl are two of the newest illicit opioids that are infiltrating the heroin market. Methoxyacetylfentanyl and cyclopropylfentanyl were reported by the Drug Enforcement Administration (DEA) in their third quarter report of 2017 to have been chemically identified seven and five t...

journal_title：Journal of analytical toxicology

authors： Fogarty MF,Papsun DM,Logan BK

更新日期：2018-11-01 00:00:00

abstract：:The National Institute of Standards and Technology (formerly the National Bureau of Standards), in cooperation with the College of American Pathologists (CAP), has certified the concentrations of phencyclidine (PCP) in two new reference materials (RMs). One of these materials is Standard Reference Material (SRM) 1511,...

journal_title：Journal of analytical toxicology

authors： Tai SS,Christensen RG,Coakley K,Ellerbe P,Long T,Welch MJ

更新日期：1996-01-01 00:00:00