Resorcylic Acid Lactones in Urine Samples of Croatian Farm Animals.

abstract：:Poisoning with agricultural chemicals is a major threat for wildlife all over the world. We have developed and validated an analytical scheme aimed to the identification and quantification of a wide range of pesticides in fresh liver from wildlife specimens that are routinely delivered to the forensic laboratories for...

journal_title：Journal of analytical toxicology

authors： Luzardo OP,Ruiz-Suárez N,Valerón PF,Camacho M,Zumbado M,Henríquez-Hernández LA,Boada LD

更新日期：2014-04-01 00:00:00

abstract：:Caffeine is the most widely consumed drug in the world with coffee representing a major source of intake. Despite widespread availability, various medical conditions necessitate caffeine-restricted diets. Patients on certain prescription medications are advised to discontinue caffeine intake. Such admonition has impli...

journal_title：Journal of analytical toxicology

authors： McCusker RR,Fuehrlein B,Goldberger BA,Gold MS,Cone EJ

更新日期：2006-10-01 00:00:00

abstract：:Part I. Expert 4: The object of this study was to investigate the applicability of commercially available expert system shells to interpretation in forensic toxicology. Amitriptyline toxicology was selected as a pilot trial. Blood and tissue concentrations of amitriptyline and nortriptyline in fatal and nonfatal amitr...

journal_title：Journal of analytical toxicology

authors： Spiehler V,Spiehler E,Osselton MD

更新日期：1988-07-01 00:00:00

abstract：:In June 1986, an epidemic of poisoning occurred in Sierra Leone, West Africa; it involved 49 persons--with 14 deaths. Our laboratory's approach and investigation of this incident is described. Using positive chemical ionization mass spectrometry and nuclear magnetic resonance spectroscopy, the toxicant was identified ...

journal_title：Journal of analytical toxicology

authors： Hill RH Jr,Alley CC,Ashley DL,Cline RE,Head SL,Needham LL,Etzel RA

更新日期：1990-07-01 00:00:00

abstract：:Oral fluid (OF) is increasingly used for clinical, forensic and workplace drug testing as an alternative to urine. Uncertainties surrounding OF collection device performance, drug stability and testing reproducibility may be partially responsible for delays in the implementation of OF testing in regulated drug testing...

journal_title：Journal of analytical toxicology

authors： Samano KL,Anne L,Johnson T,Tang K,Sample RH

更新日期：2015-10-01 00:00:00

abstract：:A high performance liquid chromatographic method is reported, which incorporates three internal standards (I-cinchonidine, N-propylprocainamide, and para-chlorodisopyramide) for the simultaneous quantitation of four commonly prescribed antiarrhythmic drugs: quinidine, procainamide, N-acetylprocainamide, and disopyrami...

journal_title：Journal of analytical toxicology

authors： Bridges RR,Jennison TA

更新日期：1983-03-01 00:00:00

abstract：:A 24-year-old man known to consume illegal drugs was found dead in his apartment. A reclosable plastic zipper bag containing several hundred milligrams of a brown powder was found close to the dead body and the first assumption of the investigators was death due to heroin intoxication. Therefore, a legal autopsy was o...

journal_title：Journal of analytical toxicology

authors： Dussy FE,Hangartner S,Hamberg C,Berchtold C,Scherer U,Schlotterbeck G,Wyler D,Briellmann TA

更新日期：2016-11-01 00:00:00

abstract：:A sensitive and rugged gas chromatographic-mass spectrometric (GC-MS) method was developed for determining 11 polycyclic aromatic hydrocarbons (PAHs) in 4-g specimens of human lung, breast, and liver tissue. The method quantitation limit (MQL) was 0.01-0.02 ng/g for benzo[a]pyrene (BaP) and six other five- and six-rin...

journal_title：Journal of analytical toxicology

authors： Beach JB,Pellizzari E,Keever JT,Ellis L

更新日期：2000-11-01 00:00:00

abstract：:An arsenic death was investigated six and one half years after the demise. Analysis of tissue embedded in paraffin blocks demonstrated toxic concentrations. Spectrophotometry was employed with the use of a hydride generator to provide specificity and sensitivity to less than 0.05 microgram. ...

journal_title：Journal of analytical toxicology

authors： Bednarczyk LR,Matusiak W

更新日期：1982-09-01 00:00:00

abstract：:Vitreous humor is a potential alternative matrix for postmortem toxicology drug screens when peripheral blood is unavailable. It is easily and reliably collected and may not suffer from the same postmortem redistribution as seen in blood. Here, we compared the concentrations of 7 acidic drugs (acetaminophen, ibuprofen...

journal_title：Journal of analytical toxicology

authors： Hubbard JA,Navarrete AL,Fitzgerald RL,McIntyre IM

更新日期：2019-11-06 00:00:00

abstract：:Improvements have been made in recent years in on-site or point-of-care (POC) immunoassay testing devices. We evaluated the DrugCheck 9 cup, a new qualitative visually read, competitive binding, immunoassay cup that measures nine analytes. The study was performed according to the recent National Laboratory Certificati...

journal_title：Journal of analytical toxicology

authors： Taylor EH,Pizzo P

更新日期：2004-04-01 00:00:00

abstract：:Propane can be responsible for several types of lethal intoxication and explosions. Quantifying it would be very helpful to determine in some cases the cause of death. Some gas chromatography-mass spectrometry (GC-MS) methods of propane measurements do already exist. The main drawback of these GC-MS methods described ...

journal_title：Journal of analytical toxicology

authors： Smith F,Augsburger M,Varlet V

更新日期：2014-03-01 00:00:00

abstract：:A high-performance liquid chromatographic method was used for the detection of etodolac in equine serum and urine. The method consisted of a one-step liquid-liquid extraction, separation on a reversed-phase (RP-18) column and detection using an ultraviolet detector. Additional confirmation methods included a HPLC coup...

journal_title：Journal of analytical toxicology

authors： Koupai-Abyazani MR,Esaw B,Laviolette B

更新日期：1999-05-01 00:00:00

abstract：:A rapid and simple method is described for the separation of quinidine (Q), its metabolites 3-hydroxyquinidine (30HQ) and 2'oxoquinidinone (QD) as well as the quinidine salt contaminant, dihydroquinidine (DHQ) in plasma by high pressure liquid chromatography (HPLC). A silica column was used with methanol: 1 N ammonium...

journal_title：Journal of analytical toxicology

authors： Pershing LK,Peat MA,Finkle BS

更新日期：1982-05-01 00:00:00

abstract：:Screening for emerging drugs of abuse, specifically synthetic cathinones and synthetic cannabinoids, is difficult for high-throughput laboratories as immunoassay kits are often unavailable. Consequently, most laboratories employ liquid chromatography-tandem mass spectrometry (LC-MS-MS) screening, which can be complex ...

journal_title：Journal of analytical toxicology

authors： Neifeld JR,Regester LE,Holler JM,Vorce SP,Magluilo J Jr,Ramos G,Bosy TZ

更新日期：2016-06-01 00:00:00

abstract：:An enzyme multiplied immunoassay technique (EMIT) was used to test for opiates (morphine, hydromorphone, and codeine) in extracts of blood, bile, and tissue homogenates. All immunoassay opiate positive specimens were then tested by a reversed-phase liquid chromatographic procedure using electrochemical detection (LCEC...

journal_title：Journal of analytical toxicology

authors： Hepler BR,Sutheimer C,Sunshine I,Sebrosky GF

更新日期：1984-03-01 00:00:00

abstract：:Hop-derived iso-α-acid (IAA) ingredient congeners are specific to beer. Concentrations of IAAs were determined in blood of five volunteers over 6 h following the consumption of small volumes of beer containing relatively high (Pale Ale beer) or low (wheat beer) concentrations of IAAs. IAAs were quickly absorbed with p...

journal_title：Journal of analytical toxicology

authors： Rodda LN,Gerostamoulos D,Drummer OH

更新日期：2014-07-01 00:00:00

abstract：:Preliminary data regarding the use of vernix caseosa (VC) as an alternative to other biological specimens for the determination of fetal cocaine exposure are presented. Advantages of VC analysis include its presence on all newborn babies, historical record of drug exposure, and ease of collection and storage. Fifteen ...

journal_title：Journal of analytical toxicology

authors： Moore C,Dempsey D,Deitermann D,Lewis D,Leikin J

更新日期：1996-10-01 00:00:00

abstract：:In clinical and forensic toxicology, general unknown screening is used to detect and identify exogenous compounds. In this study, we aimed to develop a fast (15 min) comprehensive screening method for 500 toxicologically relevant analytes based on ultra-performance liquid chromatography (UPLC) coupled with a quadrupol...

journal_title：Journal of analytical toxicology

authors： Humbert L,Grisel F,Richeval C,Lhermitte M

更新日期：2010-11-01 00:00:00

abstract：:In previous experimental studies on heroin metabolites excretion in urine, the first sample was often collected a few hours after intake. In forensic cases, it is sometimes questioned if a positive urine result is expected e.g., 30 min after intake. The aim of this study was to investigate urinary excretion of heroin ...

journal_title：Journal of analytical toxicology

authors： Høiseth G,Gottås A,Berg T,Arnestad M,Halvorsen PS,Bachs LC

更新日期：2017-06-01 00:00:00

abstract：:An analytical procedure for the determination of the new pain medication tapentadol and its main metabolite N-desmethyltapentadol (DMT), in urine and oral fluid has been developed and validated using liquid chromatography with tandem mass spectral detection (LC-MS-MS). Oral fluid was collected using Quantisal™ devices...

journal_title：Journal of analytical toxicology

authors： Coulter C,Taruc M,Tuyay J,Moore C

更新日期：2010-10-01 00:00:00

abstract：:This article reports the investigation by 1H nuclear magnetic resonance (1H NMR) spectroscopy of biological fluids in a case of intentional poisoning with tetrahydrofuran (THF). Occupational exposures to this solvent are well documented, but acute poisoning cases are extremely rare, and the one presented here is the s...

journal_title：Journal of analytical toxicology

authors： Cartigny B,Azaroual N,Imbenotte M,Sadeg N,Testart F,Richecoeur J,Vermeersch G,Lhermitte M

更新日期：2001-05-01 00:00:00

abstract：:Separating drugs which are both polar and basic has long been difficult because of the limited operating pH range of conventional HPLC columns. This paper describes a liquid chromatographic method capable of being used with either diode-array or mass spectrometric detection for the identification and quantitation of 1...

journal_title：Journal of analytical toxicology

authors： Goeringer KE,McIntyre lM,Drummer OH

更新日期：2003-01-01 00:00:00

abstract：:The dramatic rise in maternal drug abuse and the incidence of positive drug findings during neonatal testing has increased the need for prenatal toxicological testing for drugs of abuse. Human amniotic fluid samples collected after 13-39 weeks of pregnancy were screened for cocaine metabolite (benzoylecgonine) by fluo...

journal_title：Journal of analytical toxicology

authors： Ripple MG,Goldberger BA,Caplan YH,Blitzer MG,Schwartz S

更新日期：1992-09-01 00:00:00

abstract：:The testing for drugs of abuse in hair is increasingly used to detect illicit substances. Laboratories have implemented various decontamination, or washing, procedures in order to eliminate concerns regarding potential contamination of the hair with drug from the environment. However, the effect of these decontaminati...

journal_title：Journal of analytical toxicology

authors： Paulsen RB,Wilkins DG,Slawson MH,Shaw K,Rollins DE

更新日期：2001-10-01 00:00:00

abstract：:A rapid and sensitive solid-phase extraction method for the lysergic acid diethylamide (LSD) metabolite 2-oxo-3-hydroxy-LSD (O-H-LSD) was developed for use in a forensic laboratory. The method uses a positive-pressure manifold anion-exchange polymer-based solid-phase extraction with subsequent analysis by liquid chrom...

journal_title：Journal of analytical toxicology

authors： Horn CK,Klette KL,Stout PR

更新日期：2003-10-01 00:00:00

abstract：:We devised a highly sensitive method for simultaneously determining methamphetamine (MA) and amphetamine (AP) enantiomers, desmethylselegiline (DMSG) and selegiline (SG), in human hair using a derivatization technique and high-performance liquid chromatography-electrospray ionization-mass spectrometry (HPLC-ESI-MS). M...

journal_title：Journal of analytical toxicology

authors： Nishida K,Itoh S,Inoue N,Kudo K,Ikeda N

更新日期：2006-05-01 00:00:00

abstract：:Cyclopropylfentanyl is a fentanyl analog implicated in 78 deaths in Europe and over 100 deaths in the United States, but toxicological information including metabolism data about this drug is scarce. The aim of this study was to provide the exact structure of abundant and unique metabolites of cyclopropylfentanyl alon...

journal_title：Journal of analytical toxicology

authors： Vikingsson S,Rautio T,Wallgren J,Åstrand A,Watanabe S,Dahlén J,Wohlfarth A,Konradsson P,Wu X,Kronstrand R,Gréen H

更新日期：2019-09-10 00:00:00

abstract：:Cannabinoids were extracted from serum with C18 SPE cartridges and analyzed as their trimethylsilyl (TMS) derivatives. A benchtop gas chromatography-tandem mass spectrometry (GC-MS-MS) system based on an ion trap with external ionization was used. Quantitation was done in relation to trideuterated internal standards i...

journal_title：Journal of analytical toxicology

authors： Weller JP,Wolf M,Szidat S

更新日期：2000-07-01 00:00:00

abstract：:To determine the degree of ethanol absorption and the resultant formation and urinary excretion of its conjugated metabolites following intensive use of high ethanol content mouthwash, 10 subjects gargled with Listerine(®) antiseptic 4 times daily for 3¼ days. First morning void urine specimens were collected on each ...

journal_title：Journal of analytical toxicology

authors： Reisfield GM,Goldberger BA,Pesce AJ,Crews BO,Wilson GR,Teitelbaum SA,Bertholf RL

更新日期：2011-06-01 00:00:00