Abstract:
:Sjögren syndrome is a chronic systemic disease characterized by polyglandular tissue destruction leading to keratoconjunctivitis sicca (KCS) and xerostomia. Patients with primary Sjögren syndrome show evidence of KCS and xerostomia, whereas patients with secondary Sjögren syndrome suffer from KCS, xerostomia, and an autoimmune disease, most commonly rheumatoid arthritis. Certain factors cause autoimmune dysregulation leading to destruction of the acinar cells and ductal epithelia with subsequent dry eyes and dry mouth. Activated lymphocytes in patients with autoimmune diseases appear to have selective homing into the lacrimal and salivary glands leading to tissue damage. Understanding the factors involved in the immune dysregulation may improve our diagnostic and therapeutic approaches in Sjögren syndrome. Current therapeutic measures include means to increase secretion, relieve symptoms, and repair damage of the ocular surface.
journal_name
Curr Opin Ophthalmoljournal_title
Current opinion in ophthalmologyauthors
Tabbara KF,Vera-Cristo CLdoi
10.1097/00055735-200012000-00011keywords:
subject
Has Abstractpub_date
2000-12-01 00:00:00pages
449-54issue
6eissn
1040-8738issn
1531-7021journal_volume
11pub_type
杂志文章,评审abstract:PURPOSE OF REVIEW:With the expanding view of the oculofacial surgeon as experts in the realm of aesthetic surgery, familiarity with facial anatomy is essential. The purpose of this review is to present an update on the relevant facial anatomy and its application on rejuvenation. RECENT FINDINGS:Numerous studies have r...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
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abstract::Both classic descriptions and new findings in human anatomy have been limited in the past to cadaveric dissections. Although dissection still supplies most of new information, refinements in technique and the advent of high-resolution soft tissue imaging available with magnetic resonance have certainly provided a new ...
journal_title:Current opinion in ophthalmology
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journal_title:Current opinion in ophthalmology
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abstract::Acute demyelinating optic neuritis associated with multiple sclerosis (MS) is the most common cause of inflammation of the optic nerve. The Optic Neuritis Treatment Trial (ONTT) has provided important clinical data on the use of corticosteroids, and demonstrated that patients with characteristic inflammatory lesions w...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/00055735-200212000-00006
更新日期:2002-12-01 00:00:00
abstract:PURPOSE:To examine the latest theories in understanding wound healing, primarily as it pertains to refractive surgery but also, briefly, incisional surgery and nonsurgical corneal conditions (iatrogenic injury and noninfectious corneal ulcers). RECENT FINDINGS:Corneal wound healing involves transformation of fibroblas...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/00055735-200408000-00006
更新日期:2004-08-01 00:00:00
abstract::As the number and types of keratorefractive procedures increase and as the baby boomer population moves into the "cataractous decades," the number of patients requiring cataract surgery following refractive surgery grows larger each year. While technological advances in surgical instrumentation and intraocular lens (I...
journal_title:Current opinion in ophthalmology
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abstract:PURPOSE OF REVIEW:Topography-guided laser refractive surgery regularizes the front corneal surface irregularities to achieve the desired refractive outcome. This is particularly applicable in highly aberrated corneas, where wavefront aberrometry is often not possible. This article aims to review the recently published ...
journal_title:Current opinion in ophthalmology
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更新日期:2013-07-01 00:00:00
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journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/00055735-200006000-00001
更新日期:2000-06-01 00:00:00
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journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
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journal_title:Current opinion in ophthalmology
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abstract:PURPOSE OF REVIEW:To review idiopathic orbital inflammation, with particular reference to the evolving entity of ocular adnexal immunoglobulin G4 (IgG4) disease. RECENT FINDINGS:Emerging evidence suggests that sclerosing idiopathic orbital inflammation can be an IgG4-related disease and discovery of this link has furt...
journal_title:Current opinion in ophthalmology
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更新日期:2012-09-01 00:00:00
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journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0000000000000117
更新日期:2015-01-01 00:00:00
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journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/00055735-200206000-00001
更新日期:2002-06-01 00:00:00
abstract::Exfoliation syndrome is the most common identifiable cause leading to chronic open-angle glaucoma. It affects the treatment of glaucoma in various ways. The prognosis of capsular glaucoma (exfoliative glaucoma) is worse than that of open-angle glaucoma. Medical therapy and the long-term effect of laser treatment seem ...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/00055735-199504000-00003
更新日期:1995-04-01 00:00:00
abstract::Keratorefractive surgery has developed rapidly over the past decade. For patients with aphakia, however, posterior chamber lenses are safer and more predictable than refractive corneal surgery; myopia is the greatest challenge to this type of surgery. No technique as yet has an accuracy that is adequate for the gener...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
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更新日期:1993-08-01 00:00:00
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journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0000000000000657
更新日期:2020-05-01 00:00:00
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journal_title:Current opinion in ophthalmology
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doi:10.1097/ICU.0000000000000493
更新日期:2018-07-01 00:00:00
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journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0b013e3283313d1d
更新日期:2009-11-01 00:00:00
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journal_title:Current opinion in ophthalmology
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journal_title:Current opinion in ophthalmology
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journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/00055735-200002000-00010
更新日期:2000-02-01 00:00:00
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journal_title:Current opinion in ophthalmology
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journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
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journal_title:Current opinion in ophthalmology
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journal_title:Current opinion in ophthalmology
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更新日期:2017-11-01 00:00:00
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journal_title:Current opinion in ophthalmology
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更新日期:2000-08-01 00:00:00
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journal_title:Current opinion in ophthalmology
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journal_title:Current opinion in ophthalmology
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journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
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更新日期:2007-07-01 00:00:00
abstract:PURPOSE OF REVIEW:To discuss the most recent literature regarding the long-term use (≥52 weeks of follow-up) of antivascular endothelial growth factor (VEGF) therapy for neovascular age-related macular degeneration (NVAMD). RECENT FINDINGS:Intravitreal ranibizumab has been demonstrated to provide outstanding vision ou...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0b013e32835fefee
更新日期:2013-05-01 00:00:00