Current treatments and preventive strategies for radiation retinopathy.

Abstract:

PURPOSE OF REVIEW:Radiation retinopathy remains a devastating cause of visual morbidity in patients undergoing radiation for globe, orbit, and head and neck malignancies. This review discusses the recent efforts of several authors to treat radiation retinopathy once it has developed and efforts to prevent its development with early aggressive management. RECENT FINDINGS:Intravitreal anti-vascular endothelial growth factor agents and intravitreal steroid agents have been used to successfully treat radiation-induced macular edema and neovascular events secondary to radiation retinopathy. The visual outcomes, however, have varied. Recent work has been directed towards prevention of radiation retinopathy prior to its development. This has been done with preventive scatter laser and intravitreal bevacizumab therapy. Effective customization of radiation dose to the tumor has also reduced some collateral radiation damage. Preventive vitrectomy and silicone oil placement at the time of plaque brachytherapy may shield normal ocular structures from radiation injury. SUMMARY:Radiation retinopathy remains a major source of visual morbidity following radiotherapy for malignancies. Promising, albeit unproven, new therapies and preventive efforts may ameliorate the negative visual outcomes.

journal_name

Curr Opin Ophthalmol

authors

Reichstein D

doi

10.1097/ICU.0000000000000141

subject

Has Abstract

pub_date

2015-05-01 00:00:00

pages

157-66

issue

3

eissn

1040-8738

issn

1531-7021

journal_volume

26

pub_type

杂志文章,评审
  • Measuring the cornea: the latest developments in corneal topography.

    abstract:PURPOSE OF REVIEW:Corneal measurement uses Placido-disc topographers and tomographers, creating three-dimensional corneal models from cross-sectional images. Technology includes slit scanning, Scheimpflug imaging, very high frequency ultrasound, and high-speed anterior segment optical coherence tomography. RECENT FIND...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/ICU.0b013e3281ca7121

    authors: Swartz T,Marten L,Wang M

    更新日期:2007-07-01 00:00:00

  • Combined cataract and glaucoma surgery.

    abstract::The management of cataract in glaucoma patients has been continuously changing over the past decade. Extracapsular cataract extraction has been replaced by small-incision phacoemulsification with foldable lenses, and in glaucoma surgery, adjunctive antifibrotic therapy based on risk factors for failure has become stan...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/00055735-200102000-00008

    authors: Storr-Paulsen A,Bernth-Petersen P

    更新日期:2001-02-01 00:00:00

  • Glaucoma secondary to intraocular tumors: mechanisms and management.

    abstract:PURPOSE OF REVIEW:Glaucoma secondary to intraocular tumors is important to consider in eyes with a known tumor and those with unilateral or refractory glaucoma. The purpose of this review is to discuss the mechanisms and management of intraocular tumors with related secondary glaucoma. RECENT FINDINGS:Several intraocu...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/ICU.0000000000000550

    authors: Camp DA,Yadav P,Dalvin LA,Shields CL

    更新日期:2019-03-01 00:00:00

  • Biometry in cataract surgery: a review of the current literature.

    abstract:PURPOSE OF REVIEW:To review the literature in 2017 and 2018 pertaining to biometry for cataract surgery and report pertinent findings. RECENT FINDINGS:New devices using swept-source ocular coherence tomography can measure axial length in dense cataracts more frequently than common biometers. Computer-assisted registra...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/ICU.0000000000000536

    authors: Moshirfar M,Buckner B,Ronquillo YC,Hofstedt D

    更新日期:2019-01-01 00:00:00

  • Lymphoproliferative disorders of the ocular adnexa.

    abstract:PURPOSE OF REVIEW:To describe recent advances in clinical features, diagnostic tools, and treatment modalities for lymphoproliferative diseases affecting the ocular adnexa. RECENT FINDINGS:A close relationship of non-Hodgkin lymphoma with long-term use of aspirin and nonaspirin nonsteroidal antiinflammatory drugs has ...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/01.icu.0000139302.16648.80

    authors: Tovilla-Canales JL,Tovilla y Pomar JL,Ceron JR

    更新日期:2004-10-01 00:00:00

  • Management of irregular astigmatism.

    abstract::Using a liberal definition of corneal irregularity, modern videokeratoscopy may define approximately 40% of normal corneas with a toric refractive error as possessing primary irregular astigmatism. The causes of secondary forms of irregular astigmatism include corneal surgery, trauma, dystrophies, and infections. Inte...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/00055735-200008000-00007

    authors: Goggin M,Alpins N,Schmid LM

    更新日期:2000-08-01 00:00:00

  • Antivascular endothelial growth factor therapy for neovascular age-related macular degeneration.

    abstract:PURPOSE OF REVIEW:The most important recent advance in the treatment of neovascular age-related macular degeneration (AMD) is the development of antivascular endothelial growth factor (anti-VEGF) therapeutic agents that preserve and improve visual acuity by arresting choroidal neovascular growth and reducing vascular p...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/ICU.0b013e32832d25b3

    authors: Ciulla TA,Rosenfeld PJ

    更新日期:2009-05-01 00:00:00

  • Toxic optic neuropathies.

    abstract:PURPOSE OF REVIEW:Many causes of toxic optic neuropathy have been described to date and novel causes of toxicity are continuously being added to the current literature. The pathophysiological basis for the toxicity or a direct causal relationship is yet to be determined for many of these agents. This review highlights ...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/ICU.0000000000000001

    authors: Altiparmak UE

    更新日期:2013-11-01 00:00:00

  • Alternatives to allograft corneal transplantation.

    abstract:PURPOSE OF REVIEW:Corneal transplantation is the most commonly performed solid organ transplantation in the world. Despite a glorious history of more than a 100 years, the success of conventional corneal transplantation surgery is marred by problems like graft rejection,graft infection and associated glaucoma due to lo...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:

    authors: Jhanji V,Sharma N,Agarwal T,Vajpayee RB

    更新日期:2010-07-01 00:00:00

  • Effectiveness of intracorneal ring segments for keratoconus.

    abstract:PURPOSE OF REVIEW:To review the efficacy of intrastromal corneal ring segments (ICRS) for keratoconus and with other interventions such as contacts lens, keratoplasty, and corneal collagen cross-linking. RECENT FINDINGS:Changes in ICRS thickness and size, combination of procedures, and the adaptation of a more sophist...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/ICU.0000000000000582

    authors: Park SE,Tseng M,Lee JK

    更新日期:2019-07-01 00:00:00

  • Ophthalmic and neuro-ophthalmic manifestations of sarcoidosis.

    abstract:PURPOSE OF REVIEW:Sarcoidosis is a multisystemic inflammatory disease that commonly affects the eye and less often the neuro-ophthalmic pathways. The manifestations can be quite variable but can have characteristic signs and clinical features. This review provides a comprehensive overview of the various ocular and neur...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/ICU.0000000000000415

    authors: Kefella H,Luther D,Hainline C

    更新日期:2017-11-01 00:00:00

  • Cross-linking for microbial keratitis.

    abstract:PURPOSE OF REVIEW:Microbial keratitis is one of the leading causes of ocular morbidity. The standard treatment consists of antibiotics, which is intensive and is fraught with risks of antibiotic resistance. Corneal collagen cross-linking (CXL) has recently been advocated as an adjunctive therapy for management of micro...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/ICU.0000000000000271

    authors: Chan TC,Agarwal T,Vajpayee RB,Jhanji V

    更新日期:2016-07-01 00:00:00

  • Management of canalicular obstructions.

    abstract:PURPOSE OF REVIEW:The successful treatment of canalicular obstructions continues to represent a therapeutic challenge. Conjuctivodacryocystorhinostomy with a Lester Jones bypass tube is the standard treatment in these situations. Although a high rate of anatomic success can be achieved with this procedure, a relatively...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/ICU.0b013e32832ec3e0

    authors: Liarakos VS,Boboridis KG,Mavrikakis E,Mavrikakis I

    更新日期:2009-09-01 00:00:00

  • Scleral fixated secondary intraocular lenses: a review of recent literature.

    abstract:PURPOSE OF REVIEW:A variety of techniques exist for secondary intraocular lens (IOL) implantation. Of note, scleral fixated intraocular lenses have become more popular with a variety of techniques, both with and without use of sutures. Herein, we focus on reviewing recently published studies describing the long-term ou...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/ICU.0000000000000661

    authors: Patel LG,Starr MR,Ammar MJ,Yonekawa Y

    更新日期:2020-05-01 00:00:00

  • Fine-needle aspiration biopsy in the management of choroidal melanoma.

    abstract:PURPOSE OF REVIEW:Fine-needle aspiration biopsy of choroidal melanoma offers an opportunity to determine the prognosis for metastasis and provide tissue resources for further study to develop molecular-based targeted therapies. Patients increasingly desire as much information as possible about their cancer so that they...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/ICU.0b013e32835ff001

    authors: McCannel TA

    更新日期:2013-05-01 00:00:00

  • Update on retinal detachment surgery.

    abstract:PURPOSE OF REVIEW:Update on controversies in the surgical management of rhegmatogenous retinal detachment. RECENT FINDINGS:There are multiple new reports regarding the development and management of retinal detachment. Current use of oral fluoroquinolones may be associated with onset of retinal detachment, although the...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/ICU.0b013e32835f8e6b

    authors: Schwartz SG,Flynn HW Jr,Mieler WF

    更新日期:2013-05-01 00:00:00

  • Current concepts in lacrimal drainage surgery.

    abstract::Dacryocystorhinostomy remains the mainstay of treatment of acquired primary and secondary obstructions of the lacrimal drainage system. The advent of the endoscope has prompted renewed interest in the intranasal or endonasal approach to fistulae formation. As results of the intranasal approach are reported, they are c...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/00055735-199610000-00010

    authors: Yeatts RP

    更新日期:1996-10-01 00:00:00

  • Is laser trabeculoplasty the new star in glaucoma treatment?

    abstract:PURPOSE OF REVIEW:For decades, laser trabeculoplasty has been a well-proven therapeutic option in glaucoma management, and more recently, it has only gained in popularity. One reason for such popularity is that selective laser trabeculoplasty (SLT) is a therapy independent of patient adherence, which is typically low a...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章

    doi:10.1097/ICU.0000000000000732

    authors: Töteberg-Harms M,Meier-Gibbons F

    更新日期:2021-01-18 00:00:00

  • Simple limbal epithelial transplantation.

    abstract:PURPOSE OF REVIEW:Simple limbal epithelial transplant (SLET) is a technique for addressing limbal stem cell deficiency. Limbal tissue from a donor eye, typically the patient's fellow healthy eye, is transplanted onto an amniotic membrane attached to the surface of the diseased eye. SLET was developed to address limitat...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/ICU.0000000000000377

    authors: Sangwan VS,Sharp JAH

    更新日期:2017-07-01 00:00:00

  • Outcome of prematurity and retinopathy of prematurity.

    abstract::Retinopathy of prematurity is a disease that manifests soon after birth in the premature infant and may lead to a lifelong disability. More infants at risk for developing the retinopathy are surviving, and the ophthalmologist must be aware of possible vision abnormalities, such as decreased acuity, strabismus, nystagm...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/00055735-199606000-00009

    authors: Quinn GE,Dobson V

    更新日期:1996-06-01 00:00:00

  • Amniotic membrane surgery.

    abstract::Human amniotic membrane (AM) is composed of three layers: a single epithelial layer, a thick basement membrane, and an avascular stroma. Amniotic membrane has anti-adhesive properties and is felt to promote epithelialization and decrease inflammation, neovascularization, and fibrosis. Amniotic membrane transplantation...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/00055735-200108000-00006

    authors: Sippel KC,Ma JJ,Foster CS

    更新日期:2001-08-01 00:00:00

  • Health literacy and glaucoma.

    abstract:PURPOSE OF REVIEW:This review discusses the concept and measurement of health literacy, with a focus on the care of patients with glaucoma. RECENT FINDINGS:Nearly one-fourth of adults in the USA lack the skills needed to fully comprehend and act on verbal or written information in the healthcare environment. This prob...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/ICU.0b013e32835c8b0e

    authors: Muir KW,Christensen L,Bosworth HB

    更新日期:2013-03-01 00:00:00

  • Does general anesthesia or intravitreal injection affect neurodevelopment in children undergoing ophthalmic procedures?

    abstract:PURPOSE OF REVIEW:To review recent studies on potential neurodevelopmental impacts on the pediatric population through general anesthesia events or intravitreal anti-vascular endothelial growth factor (VEGF) injection. RECENT FINDINGS:Studies on this topic have been extensive with varied reported neurodevelopmental ou...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/ICU.0000000000000598

    authors: De Andrade LM,Isenberg SJ

    更新日期:2019-09-01 00:00:00

  • Ocular manifestations of West Nile virus.

    abstract:PURPOSE OF REVIEW:To review the ocular findings of patients with West Nile Virus. RECENT FINDINGS:Ocular findings have included multifocal choroiditis, vitritis, intraretinal hemorrhages, iritis, keratic precipitates, optic neuritis, branch retinal artery occlusions, and chorioretinal scarring in a case of intrauterin...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/01.icu.0000143687.45232.f1

    authors: Bakri SJ,Kaiser PK

    更新日期:2004-12-01 00:00:00

  • Eye pain in the white and quiet eye.

    abstract:PURPOSE OF REVIEW:Eye pain is one of the most common presenting symptoms in ophthalmology. It can range from bothersome to debilitating for patients, and it can be vexing for clinicians, especially in the white and quiet eye. The purpose of this review is to provide updates of recent literature regarding eye pain and t...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/ICU.0000000000000702

    authors: Kulenkamp J,McClelland CM,Lee MS

    更新日期:2020-11-01 00:00:00

  • The impact of cataract surgery on quality of life.

    abstract:PURPOSE OF REVIEW:This review summarizes the recent literature of the impact of cataract surgery from the patient's perspective, with a focus on second-generation patient reported outcome (PRO) measures that used Rasch analysis to explore their data. RECENT FINDINGS:Irrespective of the instrument utilized, the overrid...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/ICU.0b013e3283414284

    authors: Lamoureux EL,Fenwick E,Pesudovs K,Tan D

    更新日期:2011-01-01 00:00:00

  • Diagnosis and treatment of refractive errors in the pediatric population.

    abstract:PURPOSE OF REVIEW:The diagnosis and successful treatment of visually significant refractive errors in children are a subject of continued study and debate. RECENT FINDINGS:Treatment of significant refractive errors is widely accepted to reduce lifelong vision loss from amblyopia. Children aged 3-5 years may be screene...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/ICU.0b013e328244dfed

    authors: Braverman R

    更新日期:2007-09-01 00:00:00

  • The diagnosis of visual field progression in glaucoma.

    abstract::The detection of true visual field deterioration in glaucoma is of fundamental importance but is limited by inherent variability of the measurements. New techniques have been developed that use powerful statistical regression analysis methods to objectively quantify progression of visual field defects. These have be...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章

    doi:10.1097/00055735-199404000-00016

    authors: Fitzke FW,McNaught AI

    更新日期:1994-04-01 00:00:00

  • Current imaging of the optic disk and retinal nerve fiber layer.

    abstract::The optic nerve head and the retinal nerve fiber layer (RNFL) are the sites of clinically detectable glaucomatous tissue damage. Photographic techniques are used to document the optic disk and the RNFL to monitor patients with suspected primary open-angle glaucoma or to follow-up patients already suffering from this d...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/00055735-199604000-00017

    authors: Burk RO,Völcker HE

    更新日期:1996-04-01 00:00:00

  • Retinoblastoma management: advances in enucleation, intravenous chemoreduction, and intra-arterial chemotherapy.

    abstract:PURPOSE OF REVIEW:To provide an update on current management of retinoblastoma RECENT FINDINGS:The current major treatment strategies for retinoblastoma involve enucleation, intravenous chemoreduction, and intra-arterial chemotherapy. Enucleation is reserved for eyes with extensive retinoblastoma, in which there is no...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/ICU.0b013e328338676a

    authors: Shields CL,Shields JA

    更新日期:2010-05-01 00:00:00