Computational and experimental characterization of physically clustered simple sequence repeats in plants.

abstract：:The segregation and random assortment of characters observed by Mendel have their basis in the behavior of chromosomes in meiosis. But showing this actually to be the case requires a correct understanding of the meiotic behavior of chromosomes. This was achieved only gradually, over several decades, with much dispute ...

journal_title：Genetics

authors： Koszul R,Meselson M,Van Doninck K,Vandenhaute J,Zickler D

更新日期：2012-06-01 00:00:00

abstract：:Studies of transcriptional gene silencing in Drosophila melanogaster suggest that most of chromosome 4 resembles pericentric heterochromatin. However, some modifiers of position-effect variegation, including chromosome 4 dosage and loss of SU(VAR)3-9, have different effects on silencing in pericentric vs. distal arm c...

journal_title：Genetics

authors： Haynes KA,Gracheva E,Elgin SC

更新日期：2007-03-01 00:00:00

abstract：:The importance of quantifying and accounting for stochastic genotyping errors when analyzing microsatellite data is increasingly being recognized. This awareness is motivating the development of data analysis methods that not only take errors into consideration but also recognize the difference between two distinct cl...

journal_title：Genetics

authors： Johnson PC,Haydon DT

更新日期：2007-02-01 00:00:00

abstract：:We study the establishment probabilities of locally adapted mutations using a multi-type branching process framework. We find a surprisingly simple and intuitive analytical approximation for the establishment probabilities in a symmetric two-deme model under the assumption of weak (positive) selection. This is the fir...

journal_title：Genetics

authors： Tomasini M,Peischl S

更新日期：2018-07-01 00:00:00

abstract：:A spontaneous lethal mutation rate approximately twenty to thirty times greater than normal has been discovered in second and third chromosomes derived from an irradiated isogenic line and paired with marked inversion chromosomes. Mutations resulting in reductions of viability of varying magnitude short of complete le...

journal_title：Genetics

authors： Kidwell MG,Kidwell JF,Nei M

更新日期：1973-09-01 00:00:00

abstract：:Two-dimensional paper chromatography was performed on methanol extracts of leaves of hexaploid bread wheat, Triticum aestivum L. em. Thell. cultivar Chinese Spring, and of the available nullisomic-tetrasomic compensating lines, the tetrasomic lines and the ditelocentric lines. The chromatograms had 27 spots identified...

journal_title：Genetics

authors： Neuman PR,Waines JG,Hilu KW,Barnhart D

更新日期：1983-02-01 00:00:00

abstract：:Various management strategies aim at maintaining pesticide resistance frequency under a threshold value by taking advantage of the benefit of the fitness penalty (the cost) expressed by the resistance allele outside the treated area or during the pesticide selection "off years." One method to estimate a fitness cost i...

journal_title：Genetics

authors： Roux F,Giancola S,Durand S,Reboud X

更新日期：2006-06-01 00:00:00

abstract：:High-density genotyping of single-nucleotide polymorphisms (SNPs) enables detection of quantitative trait loci (QTL) by linkage disequilibrium (LD) mapping using LD between markers and QTL and the subsequent use of this information for marker-assisted selection (MAS). The success of LD mapping and MAS depends on the e...

journal_title：Genetics

authors： Andreescu C,Avendano S,Brown SR,Hassen A,Lamont SJ,Dekkers JC

更新日期：2007-12-01 00:00:00

abstract：:The Drosophila oocyte develops from a cluster of 16 interconnected cells that derive from a common progenitor. One of these cells, the oocyte, arrests in meiosis. The other cells endoreplicate their DNA and produce mRNAs and proteins that they traffic to the oocyte along a polarized microtubule cytoskeleton shared by ...

journal_title：Genetics

authors： Morris JZ,Navarro C,Lehmann R

更新日期：2003-08-01 00:00:00

abstract：:To analyze the phenotype of cells lacking the vacuolar ATPase, we inactivated the vma-1 gene, which encodes the catalytic subunit of the enzyme. Because preliminary experiments suggested the vma-1 gene was essential, we developed a method of simultaneously inactivating the gene and complementing it with a functional c...

journal_title：Genetics

authors： Ferea TL,Bowman BJ

更新日期：1996-05-01 00:00:00

abstract：:The bovine Growth Hormone gene (bGH) is an attractive candidate gene for milk production in cattle. Single-strand conformation polymorphisms at bGH were identified and used to define haplotype configurations at this gene in the Israeli Holstein dairy cattle population (Bos taurus) and in the parent animals of the Inte...

journal_title：Genetics

authors： Lagziel A,Lipkin E,Soller M

更新日期：1996-03-01 00:00:00

abstract：:The L1 family of single-pass transmembrane cell adhesion molecules (L1CAMs) is conserved from Caenorhabditis elegans and Drosophila to vertebrates and is required for axon guidance, neurite outgrowth, and maintenance of neuronal positions. The extracellular region of L1CAMs mediates cell adhesion via interactions with...

journal_title：Genetics

authors： Zhou S,Opperman K,Wang X,Chen L

更新日期：2008-11-01 00:00:00

abstract：:Electrophoretic comparisons of 40S and 55S ribosomal subunit proteins from 18 strains of Drosophila melanogaster revealed the virtual absence of allelic variation. More detailed two-dimensional studies on the large subunit proteins in 6 of the strains demonstrated additional complexity but still no interstrain variati...

journal_title：Genetics

authors： Berger EM,Weber L

更新日期：1974-12-01 00:00:00

abstract：:Survival and unscheduled DNA synthesis (UDS) were measured in a cultured insect cell line, TN-368, and a cultured mammalian cell line, V-79-4, following exposure to several fluences of ultraviolet light. TN-368 cells were approximately seven times more resistant to the lethal effects of UV than V-79 cells, as determin...

journal_title：Genetics

authors： Koval TM,Hart RW,Myser WC,Hink WF

更新日期：1977-11-01 00:00:00

abstract：:The sexual dimorphism of aggression has led to a search for its Y chromosomal correlates. We have previously confirmed that initiation of attack behavior against a conspecific male is Y-dependent in two strains of laboratory mice (NZB and CBA/H). We provide evidence that the non-pseudoautosomal region of the Y is not ...

journal_title：Genetics

authors： Roubertoux PL,Carlier M,Degrelle H,Haas-Dupertuis MC,Phillips J,Moutier R

更新日期：1994-01-01 00:00:00

abstract：:The r-X1 deficiency in maize induces nondisjunction at the second mitotic division during embryo sac formation. However, it was not known if this deficiency also induces nondisjunction during the microspore divisions. Microsporogenesis in plants lacking or containing this deficiency was compared using two approaches. ...

journal_title：Genetics

authors： Zhao ZY,Weber DF

更新日期：1988-08-01 00:00:00

abstract：:Equilibria are determined for the two-locus model in a partially selfing population when one locus is neutral and the other locus is heterotic. At an equilibrium point, the frequency of heterozygotes at the neutral locus is greater than that expected from one-locus theory, even if the heterotic locus is on a different...

journal_title：Genetics

authors： Strobeck C

更新日期：1979-05-01 00:00:00

abstract：:We consider a population that adapts to a gradually changing environment. Our aim is to describe how ecological and genetic factors combine to determine the genetic basis of adaptation. Specifically, we consider the evolution of a polygenic trait that is under stabilizing selection with a moving optimum. The ecologica...

journal_title：Genetics

authors： Kopp M,Hermisson J

更新日期：2009-12-01 00:00:00

abstract：:Using conditional probabilities and moment-generating matrices, I derived approximate algebraic equations that give expectations of gene frequency, population mean, gene frequency variance within lines, or heterozygosity, and gene frequency variance between lines, or drift, for repeated cycles of recurrent selection i...

journal_title：Genetics

authors： Silvela L

更新日期：1980-07-01 00:00:00

abstract：:The Arabidopsis short integuments 2-1 (sin2-1) mutant produces ovules with short integuments due to early cessation of cell division in these structures. SIN2 was isolated and encodes a putative GTPase sharing features found in the novel DAR GTPase family. DAR proteins share a signature DAR motif and a unique arrangem...

journal_title：Genetics

authors： Hill TA,Broadhvest J,Kuzoff RK,Gasser CS

更新日期：2006-10-01 00:00:00

abstract：:Differences in mating behaviors evolve early during speciation, eventually contributing to reproductive barriers between species. Knowledge of the genetic and genomic basis of these behaviors is therefore integral to a causal understanding of speciation. Acoustic behaviors are often part of the mating ritual in animal...

journal_title：Genetics

authors： Xu M,Shaw KL

更新日期：2019-03-01 00:00:00

abstract：:In Drosophila melanogaster, heterochromatin-induced silencing or position-effect variegation (PEV) of a reporter gene has provided insights into the properties of heterochromatin. Class I modifiers suppress PEV, and class II modifiers enhance PEV when the modifier gene is present in fewer than two doses. We have exami...

journal_title：Genetics

authors： Sass GL,Henikoff S

更新日期：1998-02-01 00:00:00

abstract：:In Neurospora crassa, DNA sequence duplications are detected and altered efficiently during the sexual cycle by a process known as RIP (repeat-induced point mutation). Affected sequences are subjected to multiple GC-to-AT mutations. To explore the pattern in which base changes are laid down by RIP we examined two sets...

journal_title：Genetics

authors： Watters MK,Randall TA,Margolin BS,Selker EU,Stadler DR

更新日期：1999-10-01 00:00:00

abstract：:The Snf1 protein kinase of the glucose signaling pathway in Saccharomyces cerevisiae is regulated by an autoinhibitory interaction between the regulatory and catalytic domains of Snf1p. Transitions between the autoinhibited and active states are controlled by an upstream kinase and the Reg1p-Glc7p protein phosphatase ...

journal_title：Genetics

authors： Kuchin S,Vyas VK,Kanter E,Hong SP,Carlson M

更新日期：2003-02-01 00:00:00

abstract：:Biology is characterized by complex interactions between phenotypes, such as recursive and simultaneous relationships between substrates and enzymes in biochemical systems. Structural equation models (SEMs) can be used to study such relationships in multivariate analyses, e.g., with multiple traits in a quantitative g...

journal_title：Genetics

authors： Valente BD,Rosa GJ,de Los Campos G,Gianola D,Silva MA

更新日期：2010-06-01 00:00:00

abstract：:The transcription factors Adr1 and Cat8 act in concert to regulate the expression of numerous yeast genes after the diauxic shift. Their activities are regulated by Snf1, the yeast homolog of the AMP-activated protein kinase of higher eukaryotes. Cat8 is regulated directly by Snf1, but how Snf1 regulates Adr1 is unkno...

journal_title：Genetics

authors： Ratnakumar S,Kacherovsky N,Arms E,Young ET

更新日期：2009-07-01 00:00:00

abstract：:Flowering is indicative of the transition from vegetative to reproductive phase, a critical event in the life cycle of plants. In soybean (Glycine max), a flowering quantitative trait locus, FT2, corresponding to the maturity locus E2, was detected in recombinant inbred lines (RILs) derived from the varieties "Misuzud...

journal_title：Genetics

authors： Watanabe S,Xia Z,Hideshima R,Tsubokura Y,Sato S,Yamanaka N,Takahashi R,Anai T,Tabata S,Kitamura K,Harada K

更新日期：2011-06-01 00:00:00

abstract：:The RNA polymerase II (Pol-II) holoenzyme, responsible for messenger RNA production, typically consists of 10-12 subunits. Our laboratory previously demonstrated that maternally deposited, long, noncoding, template RNAs are essential for programmed genome rearrangements in the ciliate Oxytricha trifallax. Here we show...

journal_title：Genetics

authors： Khurana JS,Wang X,Chen X,Perlman DH,Landweber LF

更新日期：2014-07-01 00:00:00

abstract：:Biological evolution generates a surprising amount of site-specific variability in protein sequences. Yet, attempts at modeling this process have been only moderately successful, and current models based on protein structural metrics explain, at best, 60% of the observed variation. Surprisingly, simple measures of pro...

journal_title：Genetics

authors： Jiang Q,Teufel AI,Jackson EL,Wilke CO

更新日期：2018-04-01 00:00:00

abstract：:THE FOLLOWING MODELS ARE CONSIDERED FOR THE GENETIC DETERMINATION OF QUANTITATIVE TRAITS: segregation at one locus, at two linked loci, at any number of equal and additive unlinked loci, and at one major locus and an indefinite number of equal and additive loci. In each case an appropriate likelihood is given for data...

journal_title：Genetics

authors： Elston RC,Stewart J

更新日期：1973-04-01 00:00:00