Neural tissue xenografting.

abstract：:Two monoclonal antibodies (MoAbs), F10.2 and F10.3, were selected for their ability to interfere in homotypic adhesion of human B cells. Precipitation studies and binding to intercellular adhesion molecule 1 (ICAM-1, CD54) cDNA transfected COS cells revealed that both MoAbs are directed against ICAM-1. The binding of ...

journal_title：Scandinavian journal of immunology

authors： Bloemen P,Moldenhauer G,van Dijk M,Schuurman HJ,Bloem AC

更新日期：1992-05-01 00:00:00

abstract：:The effect of anti-Igs in combination with the tumour promotor TPA on DNA and Ig synthesis in a human follicular germinal centre cell lymphoma carrying sIgM and sIgD was investigated. The lymphoma cells responded to both anti-mu and anti-delta chains and to anti-lambda light chains by DNA synthesis, as measured by met...

journal_title：Scandinavian journal of immunology

authors： Ruud E,Steen HB,Beiske K,Godal T

更新日期：1983-02-01 00:00:00

abstract：:The effect of low-dose methotrexate (MTX) treatment on the CD26 density on circulating monocytes and CD4(+) T lymphocytes or levels of soluble CD26 (sCD26) has not yet been described in rheumatoid arthritis (RA). While CD26 in T lymphocytes is involved in the activation and proliferation of T lymphocytes, little is kn...

journal_title：Scandinavian journal of immunology

authors： Ellingsen T,Hornung N,Møller BK,Hjelm-Poulsen J,Stengaard-Pedersen K

更新日期：2007-10-01 00:00:00

abstract：:The c-Met oncoprotein is a cell-surface receptor for hepatocyte growth factor (HGF). Signals through HGF and c-Met have been appreciated for their crucial roles in the development of many cell types, including liver cells. The present study examined whether c-Met is expressed in the thymus and whether c-Met/HGF signal...

journal_title：Scandinavian journal of immunology

authors： Tamura S,Sugawara T,Tokoro Y,Taniguchi H,Fukao K,Nakauchi H,Takahama Y

更新日期：1998-04-01 00:00:00

abstract：:In mice, an in vitro cell-mediated cytotoxicity is directed towards syngeneic erythrocytes used as targets. This phenomenon occurs in lymphoid organs of normal, non-immunized mice. Its intensity is greater in the thymus than in spleen or lymph nodes. The study of the nature of the cell responsible for this spontaneous...

journal_title：Scandinavian journal of immunology

authors： Charreire J,Bach JF

更新日期：1982-07-01 00:00:00

abstract：:The major subunit protein of amyloid fibrils (758) isolated from a patient with systemic amyloidosis and studied by N-terminal amino acid sequence analysis was found to be almost identical to the sequence of a V lambda IV Bence-Jones protein and a previously described A lambda IV amyloid protein. The two A lambda IV a...

journal_title：Scandinavian journal of immunology

authors： Natvig JB,Westermark P,Sletten K,Husby G,Michaelsen T

更新日期：1981-07-01 00:00:00

abstract：:Human leucocyte antigen (HLA)-G is an important molecule for maintaining an immunotolerant foetal-maternal relationship. A 14-bp insertion (+14-bp)/deletion (-14-bp) polymorphism in exon 8 of the 3' untranslated region of the HLA-G gene has been proposed to be associated with HLA-G mRNA stability and the expression of...

journal_title：Scandinavian journal of immunology

authors： Zhu Y,Huo Z,Lai J,Li S,Jiao H,Dang J,Jin C

更新日期：2010-01-01 00:00:00

abstract：:Inflammatory mediators such as interleukin-1 beta (IL-1 beta), tumour necrosis factor-alpha (TNF-alpha), and interleukin-6 (IL-6) exhibit local autocrine and paracrine effects as well as distant systemic effects on target cells. Human Kupffer cells, the fixed tissue macrophages of the liver, may modulate immune and en...

journal_title：Scandinavian journal of immunology

authors： Kutteh WH,Rainey WE,Carr BR

更新日期：1991-05-01 00:00:00

abstract：:G-protein-coupled receptors play a major role in the activation of the innate immune system, such as polymorphonuclear neutrophils. Members of the formyl peptide receptor family recognize chemotactic peptides as well the amyloïd-beta peptide and fragments of the human immunodeficiency virus envelope and may thus be im...

journal_title：Scandinavian journal of immunology

authors： Boxio R,Bossenmeyer-Pourié C,Vanderesse R,Dournon C,Nüsse O

更新日期：2005-08-01 00:00:00

abstract：:Human CD26 has dipeptidyl peptidase-4 (DPP IV) enzyme activity and binds to adenosine deaminase (ADA). CD26 is costimulatory for lymphocytes and has a circulating soluble form (sCD26). DPP IV enzyme inhibition is a new successful type 2 diabetes therapy. We examined whether the ADA binding and catalytic functions of s...

journal_title：Scandinavian journal of immunology

authors： Yu DM,Slaitini L,Gysbers V,Riekhoff AG,Kähne T,Knott HM,De Meester I,Abbott CA,McCaughan GW,Gorrell MD

更新日期：2011-02-01 00:00:00

abstract：:The effect of sera from mice bearing a T cell lymphoid leukaemia (LB) and the supernatants from short term cultures of the tumour cells were studied on cell proliferation using syngeneic and allogeneic normal and tumour cells. An inhibitory activity was demonstrated in 24-48 h supernatants of LB cells in culture and d...

journal_title：Scandinavian journal of immunology

authors： Waldner C,Mongini C,Alvarez E,Roig I,Hajos SE

更新日期：1994-09-01 00:00:00

abstract：:The pair of microH-chain and kappa L-chain transgenes encoding the Sp6 TNP/DNA-specific IgM was bred onto the rearrangement-deficient genetic background of RAG-2T mice, and onto the kappa L-chain expression-deficient background of iE kappa T mice. Bone marrow of Sp6 transgenic RAG-2T mice contained normal numbers of B...

journal_title：Scandinavian journal of immunology

authors： Andersson J,Melchers F,Rolink A

更新日期：1995-07-01 00:00:00

abstract：:During the germinal centre reaction (GC), B cells with non-functional or self-reactive antigen receptors are negatively selected by apoptosis to generate B cell repertoire with appropriate antigen specificities. We studied the molecular mechanism of Fas/CD95- and B cell receptor (BCR)-induced apoptosis to shed light o...

journal_title：Scandinavian journal of immunology

authors： Eeva J,Nuutinen U,Ropponen A,Mättö M,Eray M,Pellinen R,Wahlfors J,Pelkonen J

更新日期：2009-12-01 00:00:00

abstract：:IgG1 is cleaved in vitro by granulocyte elastase into Fc and Fab fragments. The elastase-specific Fc fragment has been previously detected in vivo. Biological activity of the fragments has been described in modulating neutrophil oxidative metabolism and enzyme release. To investigate further effects granulocyte chemot...

journal_title：Scandinavian journal of immunology

authors： Eckle I,Kolb G,Havemann K

更新日期：1991-09-01 00:00:00

abstract：:Propagermanium is an organic germanium compound with immunopotentiating activity. We examined the hepatoprotective effect of propagermanium and its mechanism in an experimental animal model of acute liver injury induced with Corynebacterium parvum (C. parvum) and lipopolysaccharide (LPS) injection. Oral pretreatment w...

journal_title：Scandinavian journal of immunology

authors： Yokochi S,Ishiwata Y,Hashimoto H,Ninomiya F,Suzuki T

更新日期：1998-08-01 00:00:00

abstract：:Epstein-Barr virus (EBV)-transformed human B cells were seeded at densities below their capacity for autostimulatory growth and the effects of interleukin 1-alpha (IL-1-alpha), interleukin 1-beta (IL-1-beta) and B-cell growth factor (BCGF) were studied. When added separately, IL-1-alpha was able to support the growth ...

journal_title：Scandinavian journal of immunology

authors： Gallagher G,Taylor N,Willdridge J

更新日期：1987-09-01 00:00:00

abstract：:22q11.2 deletion syndrome is the commonest chromosome deletion syndrome. 22q11.2 deletion may result in variable clinical phenotypes which may differ even between patients with identical deletions. Abnormal pharyngeal arch development results in defects in the development of the parathyroid glands, thymus and conotrun...

journal_title：Scandinavian journal of immunology

authors： McLean-Tooke A,Spickett GP,Gennery AR

更新日期：2007-07-01 00:00:00

abstract：:Antibodies to crude leukocyte interferon (CIF) were bound to Sepharose 4B, and CIF was chromatographed. A relationship between recovered interferon and percentage binding of the antibodies to Sepharose 4B was observed. Highest recovery was obtained when only 50%-85% of th- antibodies were bound. When CIF was subjected...

journal_title：Scandinavian journal of immunology

authors： Berg K

更新日期：1977-01-01 00:00:00

abstract：:We previously raised a rabbit antiserum (L12) against a 38 kD polypeptide which is expressed on the surface of thymocytes and peripheral T cells of an Urodele Amphibian, the Mexican axolotl (Ambystoma mexicanum). Here we show that L12 antibodies immunoprecipitate several labelled molecules from surface iodinated axolo...

journal_title：Scandinavian journal of immunology

authors： Kerfourn F,Guillet F,Charlemagne J,Tournefier A

更新日期：1993-10-01 00:00:00

abstract：:To examine the possible relationship between the cells mediating resistance to tumour cells and those mediating rejection of foreign bone marrow transplants (BMT), the effect of tumour-bearing on BMT rejection has been measured by means of the spleen colony assay. Moderate doses (less than 5.0 X 10(6] of bone marrow c...

journal_title：Scandinavian journal of immunology

authors： Miller SC,Nguyen D,Bird IA

更新日期：1988-04-01 00:00:00

abstract：:Toll-like receptor 4 (TLR4) participates in innate immunity by detecting lipopolysaccharides (LPS) of Gram-negative bacterial cell walls. TLR4 macrophage expression in mice is modulated by LPS. This fact constitutes, at least partially, the molecular basis for LPS tolerance. Very recently, the effect of interferon-gam...

journal_title：Scandinavian journal of immunology

authors： Moreno C,Merino J,Vázquez B,Ramírez N,Echeverría A,Pastor F,Sánchez-Ibarrola A

更新日期：2004-06-01 00:00:00

abstract：:With the use of the fluorescent Ca++ indicator Quin-2, we have measured changes in intracellular calcium levels in human B cells in response to anti-Ig antibodies, to Staphylococcus aureus (Staph) or to protein A. Cells of an Epstein-Barr virus-transformed mu lambda-carrying B-cell line, AZU-1, increased free cytosoli...

journal_title：Scandinavian journal of immunology

authors： Clevers HC,Bloem AC,Gmelig-Meyling F,Ballieux RE

更新日期：1985-11-01 00:00:00

abstract：:Mast-cell degranulation is triggered by the bridging of Fc receptor-bound antigen-specific immunoglobulin IgE on the cell surface. In vitro experiments suggest that antibody affinity and nonspecific IgE may affect the mast-cell function, however, their importance in vivo is unclear. Investigations of the effects of th...

journal_title：Scandinavian journal of immunology

authors： Mitchell AJ,Moss ND,Collins AM

更新日期：2002-01-01 00:00:00

abstract：:Pretreatment with D-Penicillamine of rat peritoneal macrophages markedly influences their ability to modulate Concanavalin A stimulated [3H]thymidine incorporation in non-adherent rat lymph node cells. Untreated macrophages added in high numbers to the lymphocytes (ratio lymphocytes/macrophage 7.5 : 1) depress their [...

journal_title：Scandinavian journal of immunology

authors： Binderup L,Bramm E,Arrigoni-Martelli E

更新日期：1978-04-01 00:00:00

abstract：:Antibodies to DNA (anti-DNA) play an important role in the pathogenesis of systemic lupus erythematosus (SLE). In blood, these antibodies may exist in a free, unbound state or as part of complexes with DNA. Furthermore, circulating DNA may be either complexed or free. Because of the central role of these immunoreactan...

journal_title：Scandinavian journal of immunology

authors： Björkman L,Reich CF,Pisetsky DS

更新日期：2003-06-01 00:00:00

abstract：:Dendritic cells (DCs) are specific antigen-presenting cells that play critical roles in the initiation and polarization of immune responses. DCs residing in the lungs might be detected in the bronchoalveolar lavage fluid (BALF). We analysed DC compartment in the peripheral blood and BALF of patients with allergy and i...

journal_title：Scandinavian journal of immunology

authors： Kayserova J,Zentsova-Jaresova I,Budinsky V,Rozkova D,Kopecka J,Vernerova E,Pohunek P,Skalicka V,Spisek R,Sediva A

更新日期：2012-03-01 00:00:00

abstract：:T helper 17 (TH17) cells have well-described roles in autoimmune diseases. The immune modulations of development and function of TH17 have become a key issue. In this review, we summarize the recent findings regarding the direct and indirect signalling regulatory mechanisms of TH17 cells in the general mouse model of ...

journal_title：Scandinavian journal of immunology

authors： Bi Y,Yang R

更新日期：2012-06-01 00:00:00

abstract：:Increased serum immunoglobulin A (IgA) level is a common finding in primary Sjögren's syndrome (pSS). IgA might not be properly eliminated because of an abnormal glycosylation. We reported previously that IgA1 from patients with pSS was oversialylated. We extend this finding by showing that monomeric IgA1 contains mor...

journal_title：Scandinavian journal of immunology

authors： Basset C,Durand V,Jamin C,Clément J,Pennec Y,Youinou P,Dueymes M,Roitt IM

更新日期：2000-03-01 00:00:00

abstract：:(C3H/TifxDBA/2)F1 mice, immunized with viable BALB/c plasmacytoma MOPC315 cells, produce antibodies directed against a cell-surface antigen. The strain and tissue distribution of this antigen was identical to that of the plasma cell differentiation alloantigen PC.1. The antigen is absent in the mouse strain C3H/Tif bu...

journal_title：Scandinavian journal of immunology

authors： Gaudernack G,Hannestad K

更新日期：1979-01-01 00:00:00

abstract：:Intravenous immunoglobulin (IVIG) preparations have been shown to suppress lymphocyte proliferation in vitro. This study aimed to investigate the effects of an IVIG produced by fractionation/DEAE-Sephadex adsorption on lymphocyte proliferation in vitro, with particular reference to contributions of the stabilizing age...

journal_title：Scandinavian journal of immunology

authors： Alder LB,Morgan LA,Spickett GP

更新日期：1996-12-01 00:00:00