当前位置： SCI文献检索 > JOURNAL OF ETHNOPHARMACOLOGY期刊下所有文献 > Hypoglycaemic effect of spergularia purpurea in normal and streptozotocin-induced diabetic rats.

Hypoglycaemic effect of spergularia purpurea in normal and streptozotocin-induced diabetic rats.

Abstract：

:Single and repeated oral administration of the water extracts of Spergularia purpurea (SP) at a dose of 10 mg/kg were tested on hypoglycaemic activity in normal and streptozotocin-induced diabetic rats. In normal rats, the water extract of SP decreased significantly the plasma glucose levels 4 h after single oral administration (P<0.01), and one week after repeated oral administration (P<0.05). A significant decrease of plasma glucose levels was observed 6 h after a single oral administration of the water extract of S. purpurea in severe hyperglycaemic rats (n=6) from 22.78+/-0.60 to 11.21+/-0.49 mmol/l (P<0.001). On other hand, water extract of S. purpurea normalised plasma glucose levels after two weeks of repeated oral administration in diabetic rats; 24.05+/-1.16 versus 7.18+/-0.51 mmol/l (P<0.001) at the start and 2 weeks after water extract administration, respectively. We conclude that the water extract of SP induces hypoglycaemic activity when administered orally in normal and STZ diabetic rats. In order to determine the active principle (s) responsible of the hypoglycaemic effect, preliminary phytochemical analysis of the water extract has been investigated.

journal_name

J Ethnopharmacol

journal_title

Journal of ethnopharmacology

authors

Jouad H,Eddouks M,Lacaille-Dubois MA,Lyoussi B

doi

10.1016/s0378-8741(99)00199-3

keywords:

subject

Has Abstract

pub_date

2000-07-01 00:00:00

pages

169-77

issue

1-2

eissn

0378-8741

issn

1872-7573

pii

S0378-8741(99)00199-3

journal_volume

71

pub_type

杂志文章

相关文献

JOURNAL OF ETHNOPHARMACOLOGY文献大全
  • Arginine is not responsible for the activation of nitric oxide synthase by garlic.

    abstract：:Garlic (Allium sativum L., Liliaceae) has had an important dietary and medicinal role for centuries. Its chemical constituents have beneficial effects on cardiovascular risk factors and other medicinal effects in the body. Several components of garlic are known but the individual compounds responsible for its divergen...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/0378-8741(96)01416-x

    authors： Das I,Hirani J,Sooranna S

    更新日期：1996-07-26 00:00:00

  • Chemical composition and evaluation of antioxidant activities, antimicrobial, and anti-melanogenesis effect of the essential oils extracted from Dalbergia pinnata (Lour.) Prain.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Dalbergia pinnata (Lour.) Prain (D. pinnata) is a plant widely distributed in tropical and subtropical regions of Asia, Africa, and the Americas. In humans, it is used in the prevention and treatment of diseases such as respiratory system, digestive system, cardiovascular and cerebrovascu...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2020.112731

    authors： Zhou W,He Y,Lei X,Liao L,Fu T,Yuan Y,Huang X,Zou L,Liu Y,Ruan R,Li J

    更新日期：2020-05-23 00:00:00

  • Baicalein attenuates α-synuclein aggregation, inflammasome activation and autophagy in the MPP+-treated nigrostriatal dopaminergic system in vivo.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Neuroinflammation, oxidative stress, and protein aggregation form a vicious cycle in the pathophysiology of Parkinson's disease (PD); activated microglia is the main location of neuroinflammation. A Chinese medicine book, "Shanghan Lun", known as the "Treatises on Cold damage Diseases" ha...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2016.10.040

    authors： Hung KC,Huang HJ,Wang YT,Lin AM

    更新日期：2016-12-24 00:00:00

  • Antibacterial and antibiotic modifying activity evaluation of ruminants' body fat used as zootherapeutics in ethnoveterinary practices in Northeast Brazil.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Northeast Brazilian ethnoveterinary studies associated with the medicinal use of zootherapies have shown that ruminants' body fat such as sheep (Ovis aries), goats (Capra hircus) and cows (Bos taurus) are used in diseases affecting domestic animals. AIM OF THE STUDY:The objective of this...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2018.12.012

    authors： de Queiroz Dias D,Sales DL,Andrade JC,da Silva ARP,Tintino SR,Oliveira-Tintino CDM,de Araújo Delmondes G,de Oliveira Barbosa M,Coutinho HDM,Ferreira FS,Rocha MFG,Navarro DMDAF,da Rocha SKL,da Costa JGM,Alves RRDN,Almeida WO

    更新日期：2019-04-06 00:00:00

  • In vitro studies on anti-inflammatory activities of kiwifruit peel extract in human THP-1 monocytes.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Kiwifruit is native to eastern China and many are the references about the consumption of fruits and fruits extracts of the Actinidia plants in Chinese traditional medicine as therapeutic food supplements to prevent and/or counteract numerous disorders including inflammation-related disea...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2018.12.044

    authors： D'Eliseo D,Pannucci E,Bernini R,Campo M,Romani A,Santi L,Velotti F

    更新日期：2019-04-06 00:00:00

  • Towards a better understanding of medicinal uses of the brown seaweed Sargassum in Traditional Chinese Medicine: a phytochemical and pharmacological review.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:For nearly 2000 years Sargassum spp., a brown seaweed, has been used in Traditional Chinese Medicine (TCM) to treat a variety of diseases including thyroid disease (e.g. goitre). AIMS OF THE REVIEW:To assess the scientific evidence for therapeutic claims made for Sargassum spp. in TCM an...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jep.2012.05.046

    authors： Liu L,Heinrich M,Myers S,Dworjanyn SA

    更新日期：2012-08-01 00:00:00

  • Bridging the "two cultures" in ethnopharmacology: barriers against interdisciplinarity in postgraduate education.

    abstract：:As significant contributors to the generation, dissemination and publication of scientific knowledge, graduate students have considerable leverage on publication trends and the future direction of ethnopharmacology. The rigid discipline-oriented framework of academia is often cited as responsible for impeding interdis...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2011.01.053

    authors： Owen PL,Johns T,Etkin NL

    更新日期：2011-04-12 00:00:00

  • Neuropharmacological screening of Diospyros mespiliformis in mice.

    abstract：:The neuropharmacological activities of the aqueous extract of Diospyros mespiliformis stem bark were screened in mice. The extracts effect on pentobarbital-induced sleeping time, pentylenetetrazole induced seizure, spontaneous motor activity (SMA), exploratory behaviour, and rota-rod performance (motor coordination) w...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/s0378-8741(02)00249-0

    authors： Adzu B,Amos S,Muazzam I,Inyang US,Gamaniel KS

    更新日期：2002-11-01 00:00:00

  • Antimutagenicity and induction of antioxidant defense by flavonoid rich extract of Myrcia bella Cambess. in normal and tumor gastric cells.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:The Brazilian "Cerrado" is an important source of natural products, such as Myrcia bella Cambess (MB, also known as "mercurinho"). MB leaves are popularly used for the treatment of diabetes and gastrointestinal disorders; however, only its hypoglycemic activity has been experimentally des...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2015.11.003

    authors： Serpeloni JM,Specian AF,Ribeiro DL,Tuttis K,Vilegas W,Martínez-López W,Dokkedal AL,Saldanha LL,Cólus IM,Varanda EA

    更新日期：2015-12-24 00:00:00

  • Ethnoveterinary contemporary knowledge of farmers in pre-alpine and alpine regions of the Swiss cantons of Bern and Lucerne compared to ancient and recent literature - Is there a tradition?

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:The term "traditional" is well established in European (human) medicine and even appears in recent European regulations on herbal medicinal products connected to a simplified registration. In contrast, a scientific discussion of a Traditional European Veterinary Herbal Medicine is still l...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2018.12.022

    authors： Stucki K,Cero MD,Vogl CR,Ivemeyer S,Meier B,Maeschli A,Hamburger M,Walkenhorst M

    更新日期：2019-04-24 00:00:00

  • Antiurolithiatic activity of Boldoa purpurascens aqueous extract: An in vitro and in vivo study.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Boldoa purpurascens Cav. (Nyctaginaceae) is a plant species used in traditional medicine in Cuba as antiurolithiatic. AIM OF THE STUDY:The aim of the present investigation was to evaluate the in vitro and in vivo antiurolothiatic activity of an aqueous extract from the leaves of Boldoa p...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2020.112691

    authors： Mosquera DMG,Ortega YH,Quero PC,Martínez RS,Pieters L

    更新日期：2020-05-10 00:00:00

  • The Chinese herbal formulae (Yitangkang) exerts an antidiabetic effect through the regulation of substance metabolism and energy metabolism in type 2 diabetic rats.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Type 2 diabetes mellitus (T2DM) regarded as a "hot" disease in traditional Chinese medicine (TCM). Accordingly, TCM uses a cold drug or formula such as the Chinese herbal formulae "Yitangkang" (YTK) as a treatment. YTK exhibited a good clinical antidiabetic effect in several experiments. ...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2019.111942

    authors： Han X,Yang Y,Metwaly AM,Xue Y,Shi Y,Dou D

    更新日期：2019-07-15 00:00:00

  • Exploration of the potential mechanism of the Tao Hong Si Wu Decoction for the treatment of postpartum blood stasis based on network pharmacology and in vivo experimental verification.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Tao Hong Si Wu Decoction (THSWD) is a traditional prescription for blood management in traditional Chinese medicine, THSWD consists of Paeoniae Radix Alba (Paeonia lactiflora Pall.), Rehmanniae Radix Praeparata (Rehmannia glutinosa (Gaertn.) DC.), Angelicae Sinensis Radix (Angelica sinens...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2020.113641

    authors： Xia W,Hu S,Wang M,Xu F,Han L,Peng D

    更新日期：2021-03-25 00:00:00

  • The water expelling effect evaluation of 3-O-(2'E,4'Z-decadienoyl)-20-O-acetylingenol and ingenol on H22 mouse hepatoma ascites model and their content differences analysis in Euphorbia kansui before and after stir-fried with vinegar by UPLC.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Malignant ascites (MA) effusion is mainly caused by hepatocellular, ovarian, and breast cancer etc. It has been reported that Euphorbia kansui (EK), the root of Euphorbia kansui S.L.Liou ex S.B.Ho, possessing a therapeutic effect on MA. However, the clinical applications of EK are serious...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2020.113507

    authors： Zhang Q,Ju YH,Zhang Y,Wang K,Zhang M,Chen PD,Yao WF,Tang YP,Wu JH,Zhang L

    更新日期：2021-03-01 00:00:00

  • Antiplasmodial activity of plant extracts used in west African traditional medicine.

    abstract：:Five plants originating from Ivory Coast were selected after an ethnobotanical survey, Alchornea cordifolia, Mitragyna inermis, Nauclea diderrichii, Pterocarpus santalinoides, and Terminalia glaucescens. Traditional healers for the treatment of malaria commonly used these plants. Extracts of these plants were tested o...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/s0378-8741(00)00296-8

    authors： Mustofa,Valentin A,Benoit-Vical F,Pélissier Y,Koné-Bamba D,Mallié M

    更新日期：2000-11-01 00:00:00

  • Yan-Hou-Qing formula attenuates allergic airway inflammation via up-regulation of Treg and suppressing Th2 responses in Ovalbumin-induced asthmatic mice.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Yan-Hou-Qing (YHQ), a Chinese medicine formula containing fourteen kinds of materials, has been designed for pharyngitis and cough treatment in Oriental medicine. In the present study, the anti-allergic effects and underlying mechanisms of YHQ in inhibition of airway hyper responsiveness ...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2018.11.038

    authors： Cheng BH,Hu TY,Mo LH,Ma L,Hu WH,Li YS,Liu ZQ,Qiu SQ

    更新日期：2019-03-01 00:00:00

  • Are meta-analyses of Chinese herbal medicine trials trustworthy and clinically applicable? A cross-sectional study.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Meta-analysis (MA) on Chinese herbal medicine (CHM) trials is increasingly published and indexed in major international databases but their trustworthiness and clinical applicability is uncertain. We aimed to assess the characteristics and methodological quality of MA on CHM. MATERIALS A...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jep.2014.12.028

    authors： Chung VC,Ho RS,Wu X,Fung DH,Lai X,Wu JC,Wong SY

    更新日期：2015-03-13 00:00:00

  • Antimicrobial, antioxidant and cytotoxic properties of essential oil from Dictamnus angustifolius.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Dictamnus angustifolius (Rutaceae) has been used as an alternative for folk medicine, Dictamnus dasycarpus in the treatment of rheumatism, bleeding, itching, jaundice, chronic hepatitis, and skin diseases in Xinjiang Province of China. The aim of this study was to evaluate the antimicrobi...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2014.06.055

    authors： Sun J,Wang X,Wang P,Li L,Qu W,Liang J

    更新日期：2015-01-15 00:00:00

  • Anti-inflammatory activity and gastroprotective effect of Hertia cheirifolia L. roots extract.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Hertia cheirifolia L. is used traditionally to treat rheumatic pains and known as a medicinal plant having several pharmaceutical and biological activities. The present study evaluated in vivo the anti-inflammatory and gastroprotective effects of the methanolic extract from H. cheirifolia...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2018.02.010

    authors： Majouli K,Hamdi A,Abdelhamid A,Bouraoui A,Kenani A

    更新日期：2018-05-10 00:00:00

  • In vitro antiplasmodial activity and identification, using tandem LC-MS, of alkaloids from Aspidosperma excelsum, a plant used to treat malaria in Amazonia.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Aspidosperma excelsum Benth. (Apocynaceae), a native tree in the Brazilian Amazonia, is traditionally used to treat various diseases, including malaria. AIM OF STUDY:To investigate the chemical constitution, antiplasmodial activity and cytotoxicity of samples obtained from A. excelsum tr...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2018.09.012

    authors： do Nascimento MS,Pina NDPV,da Silva ASB,Gomes LFDS,de Vasconcellos F,Brandão GC,do Nascimento MFA,de Oliveira AB,Barbosa WLR

    更新日期：2019-01-10 00:00:00

  • Permeability of rosmarinic acid in Prunella vulgaris and ursolic acid in Salvia officinalis extracts across Caco-2 cell monolayers.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Rosmarinic acid (RA), a caffeic acid-related compound found in high concentrations in Prunella vulgaris (self-heal), and ursolic acid (UA), a pentacyclic triterpene acid concentrated in Salvia officinalis (sage), have been traditionally used to treat inflammation in the mouth, and may als...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2011.07.037

    authors： Qiang Z,Ye Z,Hauck C,Murphy PA,McCoy JA,Widrlechner MP,Reddy MB,Hendrich S

    更新日期：2011-10-11 00:00:00

  • Linking resource supplies and price drivers: Lessons from Traditional Chinese Medicine (TCM) price volatility and change, 2002-2017.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Worldwide, one of the drivers of substitution and adulteration is the cost of the natural resources (plants, animals, fungi) that are ingredients of traditional medicines. Relatively few studies have been done that link prices of traditional medicine ingredients to what drives changes in ...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2018.10.010

    authors： Cunningham AB,Long X

    更新日期：2019-01-30 00:00:00

  • Evaluation of the toxicity of Solanum lycocarpum in the reproductive system of male mice and rats.

    abstract：:Powdered Solanum lycocarpum fruit is commonly used to treat diabetes, but apparently no studies have been conducted to evaluate potential adverse side effects. In the present paper the toxic effect of S. lycocarpum was evaluated in adult male Wistar rats and Swiss mice. The administration of an aqueous extract prepare...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/s0378-8741(00)00250-6

    authors： de Cássia da SeSá R,Vireque AA,Reis JE,Guerra MO

    更新日期：2000-11-01 00:00:00

  • Effect of ME-3451-106, an aqueous extract of Stichaster striatus with inhibitory activity of voluntary alcohol intake, in genetically drinker rats: Isolation and identification of the active fraction.

    abstract：:The aqueous extract obtained from Stichaster striatus Müller & Troschel (Asteroidea, Stichasteridae) has been shown to possess activity as an alcohol appetite inhibitor after oral administration in a rat model with a genetically established excessive appetite for alcohol (Wistar rats, lineage UChB). A significant decr...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2005.08.078

    authors： Font M,Bilbeny N,Contreras S,Paeile C,García H

    更新日期：2006-04-21 00:00:00

  • Traditional medicine in Bulamogi county, Uganda: its practitioners, users and viability.

    abstract：:Traditional medicine (TM) in Bulamogi (Uganda) is holistic, providing treatments for physical illnesses as well as psycho-spiritual ones. People use it to prevent and eliminate the effects of witchcraft, to appease spirits and to cure chronic illnesses. The traditional medicine practitioners (TMPs) are numerous and ha...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/s0378-8741(02)00378-1

    authors： Tabuti JR,Dhillion SS,Lye KA

    更新日期：2003-03-01 00:00:00

  • Salvia miltiorrhiza Bunge (Danshen) extract attenuates permanent cerebral ischemia through inhibiting platelet activation in rats.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Danshen is a crude herbal drug isolated from dried roots of Salvia miltiorrhiza Bunge. This plant is widely used in oriental medicine for the treatment of cardiovascular and cerebrovascular diseases. The supercritical CO2 extract from Danshen (SCED) (57.85%, 5.67% and 4.55% for tanshinone...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2017.06.023

    authors： Fei YX,Wang SQ,Yang LJ,Qiu YY,Li YZ,Liu WY,Xi T,Fang WR,Li YM

    更新日期：2017-07-31 00:00:00

  • Therapeutic effect of tripterine on adjuvant arthritis in rats.

    abstract：AIMS OF THE STUDY:Tripterygium wilfordii Hoog f., a perennial vine, is used in traditional Chinese medicine for treatment of rheumatoid arthritis. This study was to determine whether tripterine, isolated from Tripterygium wilfordii Hoog f., had therapeutic effects on adjuvant arthritis. MATERIALS AND METHODS:Adjuvant ...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2008.05.028

    authors： Li H,Zhang YY,Tan HW,Jia YF,Li D

    更新日期：2008-08-13 00:00:00

  • Lythrum salicaria L. herb and gut microbiota of healthy post-weaning piglets. Focus on prebiotic properties and formation of postbiotic metabolites in ex vivo cultures.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Herb of purple loosestrife (Lythrum salicaria L. from Lythraceae family) (LSH) was used in Europe since ancient times till early-20th century in the therapy of diarrhea and dysentery in human and veterinary medicine. Post-weaning diarrhea is a main problem affecting global piglet producti...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2020.113073

    authors： Dadi TH,Vahjen W,Zentek J,Melzig MF,Granica S,Piwowarski JP

    更新日期：2020-10-28 00:00:00

  • Screening of New Caledonian and Vanuatu medicinal plants for antiprotozoal activity.

    abstract：:Sixty-seven extracts of 30 medicinal plants traditionally used in New Caledonia or Vanuatu by healers to treat inflammation, fever and in cicatrizing remedies were evaluated in vitro for their antiprotozoal activity against Leishmania donovani, Leishmania amazonensis and Trypanosoma cruzi. Among the selected plants, P...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2004.10.006

    authors： Billo M,Fournet A,Cabalion P,Waikedre J,Bories C,Loiseau P,Prina E,de Arias AR,Yaluff G,Fourneau C,Hocquemiller R

    更新日期：2005-01-15 00:00:00

  • Pharmacokinetics and comparative metabolic profiling of iridoid enriched fraction of Picrorhiza kurroa - An Ayurvedic Herb.

    abstract：ETHNO-PHARMACOLOGICAL RELEVANCE:Picrosides I, II and apocynin are the main active principles present in the roots and rhizomes of Picrorhiza kurroa Royle ex. Benth (Kutki). Ethno-medicinally, the plant is used for the treatment of liver, upper respiratory tract disorders and dyspepsia, since long in Ayurveda. AIM OF T...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2016.07.072

    authors： Zahiruddin S,Khan W,Nehra R,Alam MJ,Mallick MN,Parveen R,Ahmad S

    更新日期：2017-02-02 00:00:00