Abstract：
:Tissue engineering, long a matter of myth and dream throughout the history of medicine, is now a practical reality. A wide spectrum of biological materials are used in the field of urology to treat disease and to overcome human disabilities, including tissue grafts and organ transplantation. Laboratory-engineered bioproducts for the off-the-shelf replacement and reconstruction of tissue is now almost at hand. This article presents a glimpse into the past by highlighting a number of early pioneering works in the field of tissue transplantation and cell culture technologies.
journal_name
World J Uroljournal_title
World journal of urologyauthors
Schultheiss D,Bloom DA,Wefer J,Jonas Udoi
10.1007/s003450050015keywords:
subject
Has Abstractpub_date
2000-02-01 00:00:00pages
84-90issue
1eissn
0724-4983issn
1433-8726journal_volume
18pub_type
历史文章,杂志文章abstract：OBJECTIVE:To explore efficacy and safety of Botulinum Neurotoxin Type A (BoNT-A) prostatic injection in patients with lower urinary tract symptoms (LUTS) due to benign prostatic hyperperplasia. MATERIALS AND METHODS:A phase 3 multicenter open-labeled study randomised patients to receive BoNT-A prostatic injection or o...
journal_title：World journal of urology
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1007/s00345-018-2193-y
更新日期：2018-06-01 00:00:00
abstract：PURPOSE:To evaluate histological changes in stenotic urethral tissue post-radiation therapy. Treatment of prostate cancer by radiation therapy carries a risk of off-target injury to the membranous urethra causing urethral stenosis. Limited characterization of post-radiation urethral stenosis exists in the literature. W...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-019-03031-y
更新日期：2020-09-01 00:00:00
abstract：PURPOSE:Chronic inflammation has been considered a potential risk factor for prostate cancer. Toll-like receptors (TLRs) are important in the innate immune response to pathogens and in cross talk between innate immunity and adaptive immunity. In this study, sequence variants in the TLR4 gene were investigated to determ...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-011-0690-3
更新日期：2012-04-01 00:00:00
abstract：PURPOSE:Despite the increasing number of studies confirming the importance of neoadjuvant chemotherapy (NC) in patients before radical cystectomy (RC) for bladder cancer (BCa), NC remains underused. The aim of our study was to develop a nomogram predicting the cancer-specific mortality (CSM) of patients who underwent R...
journal_title：World journal of urology
pub_type： 杂志文章,多中心研究
doi：10.1007/s00345-015-1640-2
更新日期：2016-02-01 00:00:00
abstract：PURPOSE:Urinary cytology (C) and cystoscopy remain the gold standard for the detection and screening of bladder cancer (BC). In this prospective study, we analyzed whether baseline C, ImmunoCyt (I), BTA Stat (B), hemoglobin dipstick (H), and NMP22 BladderChek (N) can predict recurrence and progression. METHODS:Urinary...
journal_title：World journal of urology
pub_type： 临床试验,杂志文章
doi：10.1007/s00345-016-1795-5
更新日期：2016-10-01 00:00:00
abstract：PURPOSE:We sought whether serum total testosterone (tT), estradiol (E2), tT/E2 ratio, and sex hormone-binding globulin (SHBG) significantly fluctuate throughout time in men with prostate cancer (PCa). METHODS:Circulating hormones were measured in a cohort of 631 candidates for radical prostatectomy. Hormone levels wer...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-012-1009-8
更新日期：2013-04-01 00:00:00
abstract：:The most important phosphates involved in urinary stone disease are carbonate apatite, brushite, and struvite. Overall, phosphate stones account for 12-20% of all stones, with a downward trend for struvite and an increase in carbonate apatite being observed in the last decade. The physicochemical basis for the formati...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s003450050152
更新日期：1999-10-01 00:00:00
abstract：PURPOSE:To assess long-term clinical and oncological outcome in women undergoing radical cystectomy and ileal neobladder reconstruction for invasive bladder cancer. METHODS:From 1995 to 2010, a total of 121 women with clinically organ-confined urothelial carcinoma underwent radical cystectomy with an orthotopic ileal ...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-012-0837-x
更新日期：2012-12-01 00:00:00
abstract：BACKGROUND:Several studies have reported brain activations and functional connectivity (FC) during micturition using functional magnetic resonance imaging (fMRI) and concurrent urodynamics (UDS) testing. However, due to the invasive nature of UDS procedure, non-invasive resting-state fMRI is being explored as a potenti...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-021-03599-4
更新日期：2021-01-29 00:00:00
abstract：PURPOSE:The Grade Group (GG) classification is recommended by guidelines as a reliable prognostic factor of prostate cancer. However, most studies have been performed on the Caucasian population. Our objective was to validate GG classification as a safe way to classify intermediate- and high-risk patients with African ...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-019-02931-3
更新日期：2020-06-01 00:00:00
abstract：PURPOSE:To assess the feasibility, safety, and outcomes of an expedited One-Stop prostate cancer (PCa) diagnostic pathway. PATIENTS AND METHODS:We identified 370 consecutive patients who underwent multiparametric magnetic resonance imaging (mpMRI) and transrectal ultrasound fusion prostate biopsy (MRI/TRUS-PBx) from o...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-019-02835-2
更新日期：2020-04-01 00:00:00
abstract：:Renal cystic disease, ranging from simple cysts to autosomal dominant polycystic kidney disease (ADPKD), can lead to significant complications such as pain, hypertension, infection, upper urinary tract obstruction, and even renal failure. For patients with preserved renal function, laparoscopic ablation of renal cysts...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/pl00007076
更新日期：2000-09-01 00:00:00
abstract：:The field of tissue engineering has developed in phases: initially researchers searched for "inert" biomaterials to act solely as replacement structures in the body. Then, they explored biodegradable scaffolds--both naturally derived and synthetic--for the temporary support of growing tissues. Now, a third phase of ti...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s00345-008-0273-0
更新日期：2008-08-01 00:00:00
abstract：PURPOSE:Treatment options for antimuscarinic refractory neurogenic detrusor overactivity (NDO) are botulinum toxin type A injections (BTX-A) and augmentation cystoplasty (AC). We estimated initial and cumulative 5-year costs of these treatments. MATERIALS AND METHODS:Base case is an individual with antimuscarinic refr...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-010-0618-3
更新日期：2011-02-01 00:00:00
abstract：:Due to its unique biological behavior, late relapse (LR) of testicular cancer has recently been described as an own tumor entity. It is currently defined as tumor recurrence more than 2 years after complete remission following primary treatment including chemotherapy. The incidence ranges from 2 to 6%, with a median r...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s00345-004-0397-9
更新日期：2004-04-01 00:00:00
abstract：PURPOSE:Although the role of lymph node dissection (LND) is well defined in many urological settings, uncertainty regarding need for LND still exists for patients with renal cell carcinoma (RCC). The aim of the current review is to highlight the rationale for performing or omitting LND at the time of renal surgery. ME...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s00345-016-1886-3
更新日期：2017-04-01 00:00:00
abstract：BACKGROUND:In this study, we investigated the influence of hematuria on the performance of the bladder tumor antigen (BTA) tests in a clinical cohort and in an experimental model. MATERIALS AND METHODS:Urine samples from a cohort of 126 subjects (64 with BCa and 62 controls) were analyzed by ELISA for hemoglobin and B...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-012-0935-9
更新日期：2012-12-01 00:00:00
abstract：PURPOSE:To review current practices in manual bladder washouts (MBW) for haematuria with clot retention, comparing those conducted by a urology unit to other inpatient services. Secondly, to describe a standardised protocol for MBWs. METHODS:Prospective data were collected for patients treated for clot retention, from...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-018-2346-z
更新日期：2018-12-01 00:00:00
abstract：INTRODUCTION:The current pool of organs available for transplantation does not cover requirements, for this reason non-standard risk donors need to be incorporated into the pool. In this way, donors with small renal tumour are considered for transplantation after bench tumour excision. The aim of our study was to analy...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-020-03463-x
更新日期：2020-09-30 00:00:00
abstract：:We are fortunate that our ability to diagnose the specific adrenal entities that mandate a surgical approach is extremely accurate. The combination of analytical methodology to measure the appropriate adrenocortical and medullary hormone production and the radiology techniques for localization are superb. The manageme...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s003450050103
更新日期：1999-02-01 00:00:00
abstract：PURPOSE:To compare oncological, functional, and toxicity outcomes of patients with radiation-recurrent prostate cancer (PCa) after external beam radiation therapy (EBRT) or brachytherapy (BT) treated with salvage high-intensity focused ultrasound (S-HIFU) or salvage radical prostatectomy (S-RP). METHODS:This retrospec...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-019-02640-x
更新日期：2019-08-01 00:00:00
abstract：:It has been brought to our attention that the first sentence of the Conclusion in the original publication [1] is incorrect. We have removed this sentence and the correct version can be found in this Erratum. ...
journal_title：World journal of urology
pub_type： 已发布勘误
doi：10.1007/s00345-019-02929-x
更新日期：2020-09-01 00:00:00
abstract：PURPOSE:To evaluate the diagnostic and staging ability of multiparametric MRI (mpMRI) compared to radical prostatectomy (RP) specimens after dissemination of this technology to several centres. mpMRI is an evolving technique aiming to improve upon the diagnostic sensitivity of prostate biopsy for the diagnosis of prost...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-016-1960-x
更新日期：2017-06-01 00:00:00
abstract：PURPOSE:To examine patterns of crowdsourcing on the social media platform Twitter among urologists. METHODS:Urologists' public Twitter accounts were reviewed for original posts seeking clinical advice or feedback, and associated reply posts, before and after the 140-character-limit expansion in 2017. Predictors of res...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-018-2405-5
更新日期：2019-03-01 00:00:00
abstract：:Many human tumors such as bladder carcinoma that are initially responsive to chemotherapy eventually fail to respond to treatment. For most drugs, dose escalation that may be required for a cure cannot be achieved because sensitive tissues such as bone marrow limit cytotoxic therapy. Approaches to prevent or circumven...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/BF00184246
更新日期：1994-01-01 00:00:00
abstract：:We report on a 17-year-old white woman with multiple bilateral renal angiomyolipomas (AMLs) in the absence of tuberous sclerosis. Multiple hyperdense lesions were detected in both kidneys by sonography. A computed tomography (CT) scan confirmed mainly fatty tissue. Sparing as much functional tissue as possible, eight ...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-001-0242-3
更新日期：2002-09-01 00:00:00
abstract：PURPOSE:To determine retrospectively the perioperative management and outcome of transurethral prostate/bladder surgery (TURP, TURB) and transrectal prostate biopsy in hemophiliacs. METHODS:Thirty-seven hemophilic patients underwent TURP (12 patients), TURB (13 patients), or transrectal prostate biopsy (12 patients) w...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-012-0988-9
更新日期：2013-06-01 00:00:00
abstract：:The surgical complications encountered in 478 patients who underwent primary retroperitoneal lymph-node dissection for clinical stage A and B nonseminomatous testicular cancer during the period ranging from 1982 to 1992 were reviewed. There were 54 complications in 51 patients (10.6%), and there was no surgery-related...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/BF00192272
更新日期：1994-01-01 00:00:00
abstract：PURPOSE:The factors affecting spermatogenesis in adulthood in patients with hypospadias (HS) are not clearly understood. In the present study, risk factors affecting post-pubertal high serum follicle-stimulating hormone (FSH) were evaluated in patients with HS. MATERIALS AND METHODS:Among those with a history of HS su...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-019-02687-w
更新日期：2019-12-01 00:00:00
abstract：INTRODUCTION:Peyronie's disease (PD) is a localized connective tissue disorder of the penile tunica albuginea (TA) with a still obscure etiopathology. Recent studies from our laboratory have demonstrated differences in Smad3 and Smad4 gene expression of PD-fibroblasts and non-PD-fibroblasts after stimulation with recom...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-008-0320-x
更新日期：2009-02-01 00:00:00
