Abstract:
INTRODUCTION:The current pool of organs available for transplantation does not cover requirements, for this reason non-standard risk donors need to be incorporated into the pool. In this way, donors with small renal tumour are considered for transplantation after bench tumour excision. The aim of our study was to analyse our experience in using these grafts for transplantation. MATERIALS AND METHODS:Retrospective analysis from our prospective accrued database of donors with incidental renal mass used for kidney transplantation between January 2007 and August 2018. RESULTS:Twenty kidney transplantations were performed, thirteen cases received the affected kidney (after tumour removal) and seven the contralateral kidney; from six living and eleven deceased donors. Donor and recipient median age was 58 years (range 22-82) and 56.5 years (range 38-74), respectively. Mean tumour diameter was 12.7 mm (SD 9.5). Tumours resulted in two benign lesions and fifteen renal cell carcinoma. Surgical margins were negative. Two cases presented with bleeding after reperfusion was solved without repercussion. One case presented with immediate vein thrombosis. None of them present delayed graft function. After a 69 month follow-up none of the donors or the recipients presented tumour recurrence. CONCLUSIONS:Kidneys with small incidental tumours seem to be a good option for kidney transplantation in selected patients after bench surgery excision with good functional and oncologic results. More studies and longer follow-up are needed to confirm these results.
journal_name
World J Uroljournal_title
World journal of urologyauthors
Musquera M,Sierra A,Diekmann F,Perez M,Mercader C,Peri L,Esforzado N,Paredes D,Alcaraz Adoi
10.1007/s00345-020-03463-xsubject
Has Abstractpub_date
2020-09-30 00:00:00eissn
0724-4983issn
1433-8726pii
10.1007/s00345-020-03463-xpub_type
杂志文章abstract:PURPOSE:To evaluate the efficacy and safety of WX-G250, a chimeric monoclonal antibody that binds to carboxy anhydrase IX, combined with low-dose interferon-alpha (LD-IFNα) in patients with progressive metastatic renal cell carcinoma (mRCC). PATIENTS AND METHODS:Thirty-one patients, nephrectomized for the primary tumo...
journal_title:World journal of urology
pub_type: 杂志文章,多中心研究
doi:10.1007/s00345-010-0570-2
更新日期:2011-02-01 00:00:00
abstract:PURPOSE:The purpose this study is to evaluate the efficacy of multiparametric ultrasound-targeted biopsies in patients undergoing initial biopsy of the prostate for the suspicion of prostate cancer. MATERIALS AND METHODS:A total of 167 patients who are biopsy naïve underwent multiparametric ultrasound-targeted biopsy ...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-018-2187-9
更新日期:2018-05-01 00:00:00
abstract:PURPOSE:Recent studies demonstrated ongoing inverse stage migration in prostate cancer (PCa) patients towards more advanced and unfavorable tumors. The USPSTF grade D recommendation may impact this trend in North American patients. We assessed contemporary stage migration and treatment trends in a large North American ...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-018-2396-2
更新日期:2019-03-01 00:00:00
abstract::Peyronie's disease (PD, induratio penis plastica) is uncommon. Its etiology is unknown and the incidence is stated to be 1%, although more recent data suggest that it is higher. The symptoms are penile deviation and painful erection in association with penile plaques. The diagnosis is performed by palpation of the pen...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-004-0424-x
更新日期:2004-11-01 00:00:00
abstract::The 30-45% failure rate after radical cystoprostatectomy mandates that we explore and optimize multimodal therapy to achieve better disease control in these patients. Cisplatin-based multi-agent combination chemotherapy has been used with success in metastatic disease and has therefore also been introduced in patients...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-006-0113-z
更新日期:2006-11-01 00:00:00
abstract:PURPOSE:Patients with end-stage renal disease (ESRD) have an increased risk of developing renal cell carcinoma (RCC). This retrospective study compared clinical and pathological outcomes of RCC occurring in native kidneys of patients with ESRD (whether they underwent kidney transplantation or not) with those of renal t...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-014-1248-y
更新日期:2015-01-01 00:00:00
abstract::Mycophenolate mofetil (MM) is the ester derivative of mycophenolic acid (MPA), which exerts immunosuppressive activity by inhibiting de novo purine biosynthesis. Following animal models and pilot studies in human renal allograft recipients that confirmed MM's ability to prevent and half rejection episodes, 3 large mul...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/BF00182076
更新日期:1996-01-01 00:00:00
abstract:BACKGROUND:Asymptomatic bacteriuria is common in diabetic women. Treatment of asymptomatic bacteriuria is not beneficial, but the natural history of the microbiology of asymptomatic bacteriuria has not been well described. OBJECTIVE:To describe the microbiological outcomes of bacteriuria in diabetic women with untreat...
journal_title:World journal of urology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00345-005-0042-2
更新日期:2006-02-01 00:00:00
abstract::Urinary bladder cancer (UBC) ranks ninth in worldwide cancer incidence. It is more frequent in men than in women. We review the main established/proposed factors, both environmental and genetic, associated with bladder cancer etiology and prognosis. Data were extracted from previous reviews and original articles ident...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-007-0168-5
更新日期:2007-06-01 00:00:00
abstract::Many human tumors such as bladder carcinoma that are initially responsive to chemotherapy eventually fail to respond to treatment. For most drugs, dose escalation that may be required for a cure cannot be achieved because sensitive tissues such as bone marrow limit cytotoxic therapy. Approaches to prevent or circumven...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/BF00184246
更新日期:1994-01-01 00:00:00
abstract::Our objectives were to assess the value of extracorporeal shock wave lithotripsy (ESWL) in treating pediatric urolithiasis, and to determine the factors that may affect treatment success. Between January 1993 and August 2002, 129 children with upper urinary tract calculi (134 renoureteral units) were treated using a D...
journal_title:World journal of urology
pub_type: 临床试验,杂志文章
doi:10.1007/s00345-003-0385-5
更新日期:2004-06-01 00:00:00
abstract::We prospectively compared, within the same center and during the same period of time, the perioperative parameters as well as the oncological and functional results of both open retropubic (ORP) and laparoscopic radical prostatectomy (LRP). From September 1999 to September 2001, 162 patients with prostate cancer were ...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-002-0306-z
更新日期:2003-05-01 00:00:00
abstract:PURPOSE:Assess knowledge and awareness concerning human papillomavirus (HPV) infection, HPV-associated diseases, and the existence of a specific vaccine among non-HPV-screened Caucasian-European adults after the market introduction of HPV vaccines. METHODS:A cohort of 934 consecutive patients seeking their first medic...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-014-1379-1
更新日期:2015-06-01 00:00:00
abstract::It has been brought to our attention that the first sentence of the Conclusion in the original publication [1] is incorrect. We have removed this sentence and the correct version can be found in this Erratum. ...
journal_title:World journal of urology
pub_type: 已发布勘误
doi:10.1007/s00345-019-02929-x
更新日期:2020-09-01 00:00:00
abstract:INTRODUCTION:Obesity may be a risk factor for kidney donors to develop reduced renal function. The Framingham heart study suggested that visceral adipose tissue (VAT) confers a more adverse metabolic profile compared with subcutaneous adipose tissue (SAT). Asians tend to have a higher VAT composition and it is unclear ...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-018-2566-2
更新日期:2019-10-01 00:00:00
abstract:PURPOSE:The Grade Group (GG) classification is recommended by guidelines as a reliable prognostic factor of prostate cancer. However, most studies have been performed on the Caucasian population. Our objective was to validate GG classification as a safe way to classify intermediate- and high-risk patients with African ...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-019-02931-3
更新日期:2020-06-01 00:00:00
abstract:PURPOSE:To present current evidence supporting the vessel sparing technique to reconstruct bulbar urethral strictures via primary anastomosis. METHODS:English literature review of presented series of transecting and non-transecting bulbar urethroplasty from 2000 to 2018. RESULTS:Since its introduction in 2007, vessel...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-019-02867-8
更新日期:2020-12-01 00:00:00
abstract::Can urolithiasis start as an intratubular event? Under severe hyperoxaluric conditions in animal models at least crystal formation can. Recently models have been presented that assess the chances of crystal formation under more normal conditions. These models describe changes in fluid composition as this passes throug...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/BF01367659
更新日期:1997-01-01 00:00:00
abstract::Due to its unique biological behavior, late relapse (LR) of testicular cancer has recently been described as an own tumor entity. It is currently defined as tumor recurrence more than 2 years after complete remission following primary treatment including chemotherapy. The incidence ranges from 2 to 6%, with a median r...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-004-0397-9
更新日期:2004-04-01 00:00:00
abstract:PURPOSE:Despite the increasing number of studies confirming the importance of neoadjuvant chemotherapy (NC) in patients before radical cystectomy (RC) for bladder cancer (BCa), NC remains underused. The aim of our study was to develop a nomogram predicting the cancer-specific mortality (CSM) of patients who underwent R...
journal_title:World journal of urology
pub_type: 杂志文章,多中心研究
doi:10.1007/s00345-015-1640-2
更新日期:2016-02-01 00:00:00
abstract:BACKGROUND:Systemic inflammatory response (SIR) plays important roles in initiation, promotion and progression of tumor. However, the prognostic role of preoperative circulating neutrophil-lymphocyte ratio (NLR) (known as a marker of SIR) in human primary bladder cancer (BC) undergoing radical cystectomy (RC) remains c...
journal_title:World journal of urology
pub_type: 杂志文章,meta分析
doi:10.1007/s00345-018-2593-z
更新日期:2019-09-01 00:00:00
abstract::In 90 patients treated with laser prostatectomy using the Urolase (n = 50) or Ultraline (n = 40) laser fiber, the fiber-tip durability was investigated. In general the Urolase fiber tips were less damaged than the Ultraline fiber tips. At visual inspection, 62% of the Urolase fiber tips were graded as minimally damage...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/BF00183619
更新日期:1995-01-01 00:00:00
abstract:PURPOSE:Oxidative stress is believed to be one of the important etiologies in carcinogenesis that has not been systemically investigated in urothelial carcinoma (UC). Through data mining from a published transcriptomic database of UC of urinary bladders (UBUCs) (GSE31684), glutathione peroxidase 2 (GPX2) was identified...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-015-1522-7
更新日期:2015-11-01 00:00:00
abstract:PURPOSE:Urinary cytology (C) and cystoscopy remain the gold standard for the detection and screening of bladder cancer (BC). In this prospective study, we analyzed whether baseline C, ImmunoCyt (I), BTA Stat (B), hemoglobin dipstick (H), and NMP22 BladderChek (N) can predict recurrence and progression. METHODS:Urinary...
journal_title:World journal of urology
pub_type: 临床试验,杂志文章
doi:10.1007/s00345-016-1795-5
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND/AIM:The effects of printed educational material on cancer screening in women (Pap test and mammography) are well documented and confirmed by several studies. The aim of our study was to evaluate the impact of similar printed educational material on prostate cancer screening by PSA and DRE. MATERIAL AND METH...
journal_title:World journal of urology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00345-008-0258-z
更新日期:2008-08-01 00:00:00
abstract:PURPOSE:To examine the effect of marital status and gender on stage at diagnosis, tumor grade, treatment type and cancer specific mortality (CSM) in patients with localized renal cell carcinoma (RCC). METHODS:Within Surveillance, Epidemiology, and End Results registry (2001-2013), we identified 57,700 patients with T1...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-017-2082-9
更新日期:2017-12-01 00:00:00
abstract:OBJECTIVE:It has been hypothesized that endothelial dysfunction and pelvic atherosclerosis may contribute to lower urinary tract symptoms (LUTS). We assessed the relationship between cardiovascular risk factors and LUTS severity in male patients presented to urology clinic. METHODS:It is a cross-sectional study on pat...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-018-2432-2
更新日期:2019-04-01 00:00:00
abstract:PURPOSE:Nephron-sparing surgery (NSS) is the gold standard treatment for resectable renal tumors. In the last decade, laparoscopic partial nephrectomy (LPN) has evolved in technical, surgical and oncological aspects and is an accepted treatment option for local-stage renal tumors. Improvements in not only surgical tech...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-014-1404-4
更新日期:2015-10-01 00:00:00
abstract::A review of the current literature is conducted to explore the developmental aspects, animal and human experiences and the effects of pharmacological manipulation to explain the role androgens play in sexual function with special emphasis on erectile function and the erectile tissue. This review reveals that androgens...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/BF01275152
更新日期:1997-01-01 00:00:00
abstract:PURPOSE:Data assessing the effectiveness of single-use flexible ureteropyeloscopy (FURS) are limited. This study evaluates and compares single-use FURS with conventional reusable FURS. METHODS:A systematic search using electronic databases (Pubmed and Embase) was performed for studies evaluating single-use FURS in the...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-017-2131-4
更新日期:2018-04-01 00:00:00