Modulation of presumed cholinergic mesopontine tegmental neurons by acetylcholine and monoamines applied iontophoretically in unanesthetized cats.

abstract：:Fifteen percent to 35% of the United States population experiences tinnitus, a subjective "ringing in the ears". Up to 10% of those afflicted report severe and disabling symptoms. Tinnitus was induced in rats using unilateral, 1 h, 17 kHz-centered octave-band noise (116 dB SPL) and assessed using a gap-startle method....

journal_title：Neuroscience

authors： Wang H,Brozoski TJ,Turner JG,Ling L,Parrish JL,Hughes LF,Caspary DM

更新日期：2009-12-01 00:00:00

abstract：:In rats under urethane anaesthesia gamma-aminobutyric acid agonists and uptake blockers were microiontophoretically applied in the pyramidal layer of CA1 and in the apical dendrites using a twin set of multibarrelled micropipettes. Thus, the somatic and dendritic field potentials elicited by commissural stimulation we...

journal_title：Neuroscience

authors： Rovira C,Ben-Ari Y,Cherubini E

更新日期：1984-06-01 00:00:00

abstract：:The nicotinic receptor proteins and gene transcripts for the different nicotinic receptor subunits exist in human prenatal brain already at 4-5 weeks of gestation. The early presence of nicotinic receptors suggests an important role for these receptors in modulating dendritic outgrowth, establishment of neuronal conne...

journal_title：Neuroscience

authors： Hellström-Lindahl E,Seiger A,Kjaeldgaard A,Nordberg A

更新日期：2001-01-01 00:00:00

abstract：:The release of chemical transmitter from nerve terminals is critically dependent on a transient increase in intracellular Ca2+. The increase in Ca2+ may be due to influx of Ca2+ from the extracellular fluid or release of Ca2+ from intracellular stores such as mitochondria. Whether Ca2+ utilized in transmitter release ...

journal_title：Neuroscience

authors： Brailoiu E,Miyamoto MD

更新日期：2000-01-01 00:00:00

abstract：:Inflammatory processes may play a critical role in the degeneration of basal forebrain cholinergic cells that underlies some of the cognitive impairments associated with Alzheimer's disease. In the present study, the proinflammagen lipopolysaccharide, from the cell wall of Gram-negative bacteria, was used to produce i...

journal_title：Neuroscience

authors： Willard LB,Hauss-Wegrzyniak B,Wenk GL

更新日期：1999-01-01 00:00:00

abstract：:In anaesthetized albino rabbits, the cerebellar flocculus was systematically mapped with a glass microelectrode to identify the location of Purkinje cells that inhibit specific vestibulo-ocular reflex pathways. The effects of microstimulation of the flocculus Purkinje cell layer on vestibular nerve-evoked reflexes to ...

journal_title：Neuroscience

authors： Ito M,Orlov I,Yamamoto M

更新日期：1982-07-01 00:00:00

abstract：:The 5-HT(6) receptor is predominantly expressed in the CNS and has been implicated in the regulation of cognitive function. Antagonists of the 5-HT(6) receptor improve cognitive performance in a number of preclinical models and have recently been found to be effective in Alzheimer's disease patients. Systemic administ...

journal_title：Neuroscience

authors： West PJ,Marcy VR,Marino MJ,Schaffhauser H

更新日期：2009-12-01 00:00:00

abstract：:We have recently shown that the phorbol ester 12-O-tetradecanoyl-phorbol-13-acetate enhances the depolarization induced, calcium dependent release of [3H]dopamine from cultured brain neurons in the rat. In the present study the effects of 12-O-tetradecanoyl-phorbol-13-acetate on the kinetic parameters of depolarizatio...

journal_title：Neuroscience

authors： Zurgil N,Yarom M,Zisapel N

更新日期：1986-12-01 00:00:00

abstract：:Dominant and subordinate males respond differently to the stress of social interaction. After an hour of social interaction, subordinate male Anolis carolinensis have elevated serotonergic activity in hippocampus, but dominant males do not. In other species, and using other stressors, the activation of hippocampal ser...

journal_title：Neuroscience

authors： Summers CH,Summers TR,Moore MC,Korzan WJ,Woodley SK,Ronan PJ,Höglund E,Watt MJ,Greenberg N

更新日期：2003-01-01 00:00:00

abstract：:Prolonged exposure to environmental enrichment (EE) induces behavioral adaptation accompanied by detectable morphological and physiological changes. Auditory EE is associated with an increased auditory evoked potential (AEP) and increased auditory gating in the primary auditory cortex. We sought physiological correlat...

journal_title：Neuroscience

authors： Nichols JA,Jakkamsetti VP,Salgado H,Dinh L,Kilgard MP,Atzori M

更新日期：2007-03-30 00:00:00

abstract：:Ghrelin is a peptide produced in the gut with a wide range of physiological functions. Recent studies have suggested it may have potential as a neuroprotective agent in models of Parkinson's disease, reducing the impact of toxic challenges on the survival of nigral dopaminergic neurons. The presence of the ghrelin rec...

journal_title：Neuroscience

authors： Elabi OF,Duskova K,Davies JS,Lane EL

更新日期：2018-12-15 00:00:00

abstract：:Recent findings indicate that neurosteroids could act as important keys during the brain development. Fluctuations in neonatal allopregnanolone (AlloP) could result in altered pharmacological properties of the GABA(A) receptor system in adulthood. Recent studies demonstrated that neurosteroids play a critical role in ...

journal_title：Neuroscience

authors： Martín-García E,Darbra S,Pallarés M

更新日期：2008-07-17 00:00:00

abstract：:The sleep spindle rhythm of thalamic origin (7-14 Hz) displays widespread synchronization among thalamic nuclei and over most of the neocortex. The mechanisms which mediate such global synchrony are not yet well understood. Here, we theoretically address the hypothesis of Steriade and colleagues that the reticularis t...

journal_title：Neuroscience

authors： Wang XJ,Rinzel J

更新日期：1993-04-01 00:00:00

abstract：:The neuroanatomical distribution of nitric oxide synthase-immunoreactive neurons was investigated in post mortem hypothalami of 10 patients suffering from schizophrenia, eight patients with depression and 13 matched control cases. Neuronal nitric oxide synthase containing nerve cells were detected in several hypothala...

journal_title：Neuroscience

authors： Bernstein HG,Stanarius A,Baumann B,Henning H,Krell D,Danos P,Falkai P,Bogerts B

更新日期：1998-04-01 00:00:00

abstract：:Apolipoprotein E isoforms may have differential effects on a number of pathological processes underlying Alzheimer's disease. Recent studies suggest that the amount, rather than the type, of apolipoprotein E may also be an important determinant for Alzheimer's disease. Therefore, understanding the regulated synthesis ...

journal_title：Neuroscience

authors： Cedazo-Mínguez A,Hamker U,Meske V,Veh RW,Hellweg R,Jacobi C,Albert F,Cowburn RF,Ohm TG

更新日期：2001-01-01 00:00:00

abstract：:Extremely mild hypothermia to 36.0 °C is not thought to appreciably differ clinically from 37.0 °C. However, it is possible that 36.0 °C stimulates highly sensitive hypothermic signaling mechanism(s) and alters biochemistry. To the best of our knowledge, no such ultra-sensitive pathway/mechanisms have been described. ...

journal_title：Neuroscience

authors： Jackson TC,Manole MD,Kotermanski SE,Jackson EK,Clark RS,Kochanek PM

更新日期：2015-10-01 00:00:00

abstract：:Resident microglia are involved in immune responses of the central nervous system and may contribute to neuronal degeneration and death. Here, we tested in adult rats whether injection of bacterial lipopolysaccharide (which causes inflammation and microglial activation) just above the substantia nigra, results in the ...

journal_title：Neuroscience

authors： Lu X,Bing G,Hagg T

更新日期：2000-01-01 00:00:00

abstract：:To examine whether dopamine modulates cortical N-methyl-D-aspartate receptor-mediated glutamate transmission, whole-cell recordings were made from identified pyramidal cells located in layers V and VI of the medial prefrontal cortex of the rat using a slice preparation. In the presence of tetrodotoxin and the absence ...

journal_title：Neuroscience

authors： Zheng P,Zhang XX,Bunney BS,Shi WX

更新日期：1999-01-01 00:00:00

abstract：:Neurogenesis continues throughout adult life in the mammalian olfactory epithelium. This process is a dynamic state of proliferation, differentiation and cell death, probably regulated by autocrine and paracrine signals such as peptide growth factors. Previous investigations have demonstrated roles for some growth fac...

journal_title：Neuroscience

authors： Newman MP,Féron F,Mackay-Sim A

更新日期：2000-01-01 00:00:00

abstract：:Neurones in the lumbosacral spinal cord are known to play a significant role in ejaculation. In these same areas neurones containing nitric oxide synthase (NOS) have been described. This raised the question as to whether there is a physiological role for nitrous oxide (NO) in the spinal cord in sexual behavior. We fir...

journal_title：Neuroscience

authors： Brack KE,Watkins N,Pyner S,Coote JH

更新日期：2007-12-05 00:00:00

abstract：:Alternative motor responses can be prepared in parallel. Here, we used electroencephalography (EEG) to test whether the parallel preparation of alternative response options is modulated by their relative value. Participants performed a choice response task with three potential actions: isometric contraction of the lef...

journal_title：Neuroscience

authors： Reuter EM,Marinovic W,Beikoff J,Carroll TJ

更新日期：2018-03-15 00:00:00

abstract：:In order to examine differential strain susceptibility to neurotoxic effects of amphetamine and to assess the potential role of superoxide radicals in amphetamine-induced dopaminergic damage, the drug was injected to mice with different levels of copper/zinc superoxide dismutase (Cu/Zn SOD) enzyme. Administration of a...

journal_title：Neuroscience

authors： Krasnova IN,Ladenheim B,Jayanthi S,Oyler J,Moran TH,Huestis MA,Cadet JL

更新日期：2001-01-01 00:00:00

abstract：:Application of N-methyl-D-aspartate on to the dendrites of hippocampal granule cells dramatically decreased prodynorphin messenger RNA levels in the affected cells while increasing proenkephalin messenger RNA levels. Sin-1 molsidomine (an agent which releases nitric oxide) and 8-bromo-cyclic GMP were similarly effecti...

journal_title：Neuroscience

authors： Johnston HM,Morris BJ

更新日期：1994-08-01 00:00:00

abstract：:Hippocampal theta oscillations are key elements in numerous behavioral and cognitive processes. Based on the dualistic theory of theta oscillations, one can differentiate between atropine-sensitive and atropine-insensitive theta subtypes. Urethane-induced atropine-sensitive theta oscillations are driven by muscarinic ...

journal_title：Neuroscience

authors： Müller R,Struck H,Ho MS,Brockhaus-Dumke A,Klosterkötter J,Broich K,Hescheler J,Schneider T,Weiergräber M

更新日期：2012-03-15 00:00:00

abstract：:Neurons containing melanin-concentrating hormone (MCH) in the lateral hypothalamic area (LH) have been shown to promote rapid eye movement sleep (REMs) in mice. However, the downstream neural pathways through which MCH neurons influence REMs remained unclear. Because MCH neurons are considered to be primarily inhibito...

journal_title：Neuroscience

authors： Kroeger D,Bandaru SS,Madara JC,Vetrivelan R

更新日期：2019-05-15 00:00:00

abstract：:Group I metabotropic glutamate receptors (mGluR1 and mGluR5) are functionally linked to estrogen receptors and play a key role in the plasticity of central neurons. Estrogen status strongly influences sensory input from the temporomandibular joint (TMJ) to neurons at the spinomedullary (Vc/C1-2) region. This study tes...

journal_title：Neuroscience

authors： Tashiro A,Nishida Y,Bereiter DA

更新日期：2015-07-23 00:00:00

abstract：:In the nervous system, the aminoacylhistidine dipeptide carnosine (beta-alanyl-L-histidine) has been shown to be expressed in the olfactory receptor neurons and in brain astrocytes. Using immunocytochemical techniques, we report here a dense carnosine-like immunoreactivity in the subependymal layer of the rodent foreb...

journal_title：Neuroscience

authors： Peretto P,Bonfanti L,Merighi A,Fasolo A

更新日期：1998-07-01 00:00:00

abstract：:Previous studies have shown significant correlated discharges (noise correlation) and synergistic information coding among adjacent cortical neurons. In order to investigate whether such interactions are present at an earlier stage of sensory processing, we compared noise correlation and synergistic information transm...

journal_title：Neuroscience

authors： Kim MJ,Kim YB,Kang KJ,Huh N,Oh JH,Kim Y,Jung MW

更新日期：2003-01-01 00:00:00

abstract：:Lampreys are jawless vertebrates, the most basal group of extant vertebrates. This phylogenetic position makes them invaluable models in comparative studies of the vertebrate central nervous system. Lampreys have been used as vertebrate models to study the neuronal circuits underlying locomotion control and axonal reg...

journal_title：Neuroscience

authors： Valle-Maroto SM,Fernández-López B,Villar-Cerviño V,Barreiro-Iglesias A,Anadón R,Rodicio MC

更新日期：2011-10-27 00:00:00

abstract：:γ oscillations (30-120 Hz) are generated intrinsically within local networks in the mammalian olfactory bulb (OB). The OB directly receives peripheral input from olfactory sensory neurons (OSNs) that can respond to nasal airflow, and centrifugal input from neuromodulatory systems whose activities are affected by the b...

journal_title：Neuroscience

authors： Zhuang L,Zhang B,Qin Z,Wang P

更新日期：2019-02-01 00:00:00