Plasticity at glycinergic synapses in dorsal cochlear nucleus of rats with behavioral evidence of tinnitus.

abstract：:Somatosensory information from the limbs reaches the contralateral Primary Sensory Cortex (S1) with a delay of 23ms for finger, and 40ms for leg (somatosensory N20/N40). Upon arrival of this input in the cortex, motor evoked potentials (MEPs) elicited by Transcranial Magnetic Stimulation (TMS) are momentarily inhibite...

journal_title：Neuroscience

authors： Ruddy KL,Jaspers E,Keller M,Wenderoth N

更新日期：2016-10-01 00:00:00

abstract：:AMPA-type glutamate receptor (GluR) channels provide fast excitatory synaptic transmission in the CNS, but mediate also cytotoxic insults. It could be shown that AMPA-type GluR channel-mediated chronic excitotoxicity leads to an increased intracellular calcium concentration and plays an important role in neurodegenera...

journal_title：Neuroscience

authors： Jahn K,Grosskreutz J,Haastert K,Ziegler E,Schlesinger F,Grothe C,Dengler R,Bufler J

更新日期：2006-11-03 00:00:00

abstract：:Exposure to severe stress leads to development of neuropsychiatric disorders, including depression and Post-Traumatic Stress Disorder (PTSD) in at-risk individuals. Neuropeptide Y (NPY) is associated with resilience or improved recovery. Therefore exogenous administration to the brain has therapeutic potential althoug...

journal_title：Neuroscience

authors： Serova LI,Tillinger A,Alaluf LG,Laukova M,Keegan K,Sabban EL

更新日期：2013-04-16 00:00:00

abstract：:This study evaluated Fos-like immunoreactivity in lumbar spinal cord neurons following intense cold stimulation and then the modifications induced by opioid administration. Under urethane anaesthesia, the rat's right foot was stimulated by holding it in a regulated temperature bath at 15, 10, 0, -10, -15, -17.5 or -20...

journal_title：Neuroscience

authors： Abbadie C,Honoré P,Besson JM

更新日期：1994-03-01 00:00:00

abstract：:Although much prior work has focused on the known cortical pathology that defines Alzheimer's disease (AD) histologically, recent work has additionally demonstrated substantial damage to the cerebral white matter in this condition. While there is large evidence of diffuse damage to the white matter in AD, it is unclea...

journal_title：Neuroscience

authors： Lee SH,Coutu JP,Wilkens P,Yendiki A,Rosas HD,Salat DH,Alzheimer’s disease Neuroimaging Initiative (ADNI).

更新日期：2015-08-20 00:00:00

abstract：:The origin of the corticothalamic projections to the contralateral mediodorsal nucleus, the collateralization of cortical fibers and their synaptic organization in the ipsi- and contralateral mediodorsal nuclei were investigated in adult rats with double retrograde fluorescent and anterograde tracing. After tracer inj...

journal_title：Neuroscience

authors： Négyessy L,Hámori J,Bentivoglio M

更新日期：1998-06-01 00:00:00

abstract：:Non-synaptic transmission is pervasive throughout the nervous system. It appears especially prevalent in peripheral ganglia, where non-synaptic interactions between neighboring cell bodies have been described in both physiological and pathological conditions, a phenomenon referred to as cross-depolarization (CD) and t...

journal_title：Neuroscience

authors： Carvalho GB,Mulpuri Y,Damasio A,Spigelman I

更新日期：2019-12-15 00:00:00

abstract：:Using data from time-resolved cortical stimulation, intracranial neural recordings, and focal surgical resections, Lee et al. (2018) demonstrate that a small area within left posterior superior temporal gyrus (pSTG) supports the ability to produce functional morphemes but not other basic aspects of language production...

journal_title：Neuroscience

authors： Fedorenko E,Williams ZM,Ferreira VS

更新日期：2018-11-10 00:00:00

abstract：:Δ⁹ tetrahydrocannabinol (THC) and cannabidiol (CBD) are the principal psychoactive and nonpsychoactive components of cannabis. While most THC-induced behavioral effects are thought to depend on endogenous cannabinoid 1 (CB1) receptors, the molecular targets for CBD remain unclear. Here, we report that CBD and THC inhi...

journal_title：Neuroscience

authors： Xiong W,Koo BN,Morton R,Zhang L

更新日期：2011-06-16 00:00:00

abstract：:Persistence of horizontal cell (HC) light responses in extracellular solutions containing low Ca2+ plus divalent cations to block Ca2+ currents (ICa) has been attributed to Ca2+-independent neurotransmission. Using a retinal slice preparation to record both ICa and light responses, we demonstrate that persistence of H...

journal_title：Neuroscience

authors： Cadetti L,Thoreson WB,Piccolino M

更新日期：2004-01-01 00:00:00

abstract：:Mapping observed actions into the onlooker's motor system seems to provide the neurofunctional mechanisms for action understanding. Subthalamic nucleus (STN) local field potential (LFP) recordings in patients with movement disorders disclosed that network oscillations in the beta range are involved in conveying motor ...

journal_title：Neuroscience

authors： Marceglia S,Fiorio M,Foffani G,Mrakic-Sposta S,Tiriticco M,Locatelli M,Caputo E,Tinazzi M,Priori A

更新日期：2009-07-21 00:00:00

abstract：:Ghrelin is a peptide produced in the gut with a wide range of physiological functions. Recent studies have suggested it may have potential as a neuroprotective agent in models of Parkinson's disease, reducing the impact of toxic challenges on the survival of nigral dopaminergic neurons. The presence of the ghrelin rec...

journal_title：Neuroscience

authors： Elabi OF,Duskova K,Davies JS,Lane EL

更新日期：2018-12-15 00:00:00

abstract：:We studied whether interactions between the presynaptic histamine H3 and prostaglandin EP3 receptors on the noradrenergic neurons of the mouse brain cortex occur. Cerebral cortex slices from the mouse (and, in few experiments, from the rat) were preincubated with [3H]noradrenaline and then superfused with a physiologi...

journal_title：Neuroscience

authors： Schlicker E,Marr I

更新日期：1997-07-01 00:00:00

abstract：:Carbonic anhydrase activity, a marker of mouse proprioceptive neurons in adult dorsal root ganglia, is first detectable in the perinatal period, increases until postnatal day 60 and remains stable in adulthood. The onset of carbonic anhydrase staining begins after the neurons have made connections with their targets s...

journal_title：Neuroscience

authors： Mayeux V,Pons F,Baldy-Moulinier M,Valmier J

更新日期：1996-04-01 00:00:00

abstract：:Amyloid deposits in Alzheimer's disease, Down's syndrome and aged brain are composed largely of A beta protein, which is generated by proteolytic processing of beta-amyloid precursor protein. Proteases responsible for liberating the A beta protein from the precursor have not yet been identified. Here, we examined the ...

journal_title：Neuroscience

authors： Savage MJ,Iqbal M,Loh T,Trusko SP,Scott R,Siman R

更新日期：1994-06-01 00:00:00

abstract：:Social bonds, especially attachment relationships, are crucial to our health and happiness. However, what we know about the neural substrates of these bonds is almost exclusively limited to rodent models and correlational experiments in humans. Here, we used socially monogamous non-human primates, titi monkeys (Callic...

journal_title：Neuroscience

authors： Maninger N,Hinde K,Mendoza SP,Mason WA,Larke RH,Ragen BJ,Jarcho MR,Cherry SR,Rowland DJ,Ferrer E,Bales KL

更新日期：2017-04-21 00:00:00

abstract：:Slices of striatal tissue from newborn to eight-day-old rats were cultured for six to 47 days. Cholinergic neurons and fibres were then visualized by histochemical staining for acetylcholinesterase or immunocytochemical staining for choline acetyltransferase. GABA-containing neurons and fibres were visualized by immun...

journal_title：Neuroscience

authors： Ostergaard K

更新日期：1993-04-01 00:00:00

abstract：:Three-dimensional changes in the angular orientation of the head were monitored during galvanic vestibular stimulation (GVS) delivered through electrodes implanted bilaterally in the tensor tympani muscle of the guinea-pig middle ear. Bilateral GVS was delivered by passing current between both ears with the anode situ...

journal_title：Neuroscience

authors： Kim J

更新日期：2013-12-03 00:00:00

abstract：:The pathological significance of intracellular Abeta accumulation in vivo is not yet fully understood. To address this, we have studied transgenic rats expressing Alzheimer's-related transgenes that accumulate Abeta intraneuronally in the cerebral and hippocampal cortices but do not develop extracellular amyloid plaqu...

journal_title：Neuroscience

authors： Echeverria V,Ducatenzeiler A,Dowd E,Jänne J,Grant SM,Szyf M,Wandosell F,Avila J,Grimm H,Dunnett SB,Hartmann T,Alhonen L,Cuello AC

更新日期：2004-01-01 00:00:00

abstract：:Apolipoprotein E isoforms may have differential effects on a number of pathological processes underlying Alzheimer's disease. Recent studies suggest that the amount, rather than the type, of apolipoprotein E may also be an important determinant for Alzheimer's disease. Therefore, understanding the regulated synthesis ...

journal_title：Neuroscience

authors： Cedazo-Mínguez A,Hamker U,Meske V,Veh RW,Hellweg R,Jacobi C,Albert F,Cowburn RF,Ohm TG

更新日期：2001-01-01 00:00:00

abstract：:A new double-label autoradiographic glucose analog method for the sequential measurement of altered regional cerebral metabolic rates for glucose in the same animal is presented. This method is based on the sequential injection of two boluses of glucose tracer labeled with two different isotopes (short-lived 18F and l...

journal_title：Neuroscience

authors： Redies C,Diksic M,Evans AC,Gjedde A,Yamamoto YL

更新日期：1987-08-01 00:00:00

abstract：:Microglia, the primary immune cells in the brain, have been implicated as the predominant cells governing inflammation-mediated neuronal damage. In response to immunological challenges such as lipopolysaccharide (LPS), microglia are activated and subsequently inflammatory process is initiated as evidenced by the relea...

journal_title：Neuroscience

authors： Liu F,Zhou R,Yan H,Yin H,Wu X,Tan Y,Li L

更新日期：2014-12-05 00:00:00

abstract：:It has long been known that storage of information in working memory suffers as a function of proactive interference. Here we review the results of experiments using approaches from cognitive neuroscience to reveal a pattern of brain activity that is a signature of proactive interference. Many of these results derive ...

journal_title：Neuroscience

authors： Jonides J,Nee DE

更新日期：2006-04-28 00:00:00

abstract：:We examined the immunohistochemical regional distribution of calcineurin (Ca2+/calmodulin-dependent protein phosphatase) in the adult rat hippocampus, following various regional destruction. In the normal adult rat hippocampus, the calcineurin immunoreactivity showed a characteristic pattern. This protein phosphatase ...

journal_title：Neuroscience

authors： Morioka M,Nagahiro S,Fukunaga K,Miyamoto E,Ushio Y

更新日期：1997-06-01 00:00:00

abstract：:Formalin (10%) induces higher levels of licking and flexing in female than in male rats, as shown in the present study. In order to ascertain the neural and hormonal modifications that accompany these behavioural differences, we determined the activity of choline acetyltransferase in the hippocampus and the levels of ...

journal_title：Neuroscience

authors： Aloisi AM,Albonetti ME,Carli G

更新日期：1996-10-01 00:00:00

abstract：:It is becoming clear that the detection and integration of synaptic input and its conversion into an output signal in cortical neurons are strongly influenced by background synaptic activity or "noise." The majority of this noise results from the spontaneous release of synaptic transmitters, interacting with ligand-ga...

journal_title：Neuroscience

authors： Greenhill SD,Jones RS

更新日期：2007-07-29 00:00:00

abstract：:Recent studies have demonstrated that astrocytes express a variety of ion channels and neurotransmitter receptors and can modulate the activity of neurons. Since a single astrocyte makes tight contacts with many neighboring neuronal cells, they can provide efficient and wide modulation of neuronal networks. Here, we p...

journal_title：Neuroscience

authors： Yamazaki Y,Hozumi Y,Kaneko K,Li J,Fujii S,Miyakawa H,Kudo Y,Kato H

更新日期：2005-01-01 00:00:00

abstract：:Extracellular signal-regulated kinases and activator protein 1 transcription factor have been functionally linked to addiction. It has also been shown that extracellular signal-regulated kinase activation can regulate cocaine-induced expression of c-Fos and FosB, two possible components of activator protein 1. A direc...

journal_title：Neuroscience

authors： Radwanska K,Valjent E,Trzaskos J,Caboche J,Kaczmarek L

更新日期：2006-01-01 00:00:00

abstract：:The sympathetic nervous system plays a role in carcinogenesis wherein locally released sympathetic neurotransmitters affect proliferation, angiogenesis, vessel permeability, lymphocyte traffic and cytokine production. The present in vivo study was designed to investigate whether surgical sympathectomy, both unilateral...

journal_title：Neuroscience

authors： Raju B,Haug SR,Ibrahim SO,Heyeraas KJ

更新日期：2007-11-09 00:00:00

abstract：:We have previously described a population of 5-hydroxytryptamine neurons which repetitively fires bursts of usually two (but occasionally three or four) action potentials, with a short (<20 ms) interspike interval within a regular low-frequency firing pattern. Here we used a paradigm of electrical stimulation comprisi...

journal_title：Neuroscience

authors： Gartside SE,Hajós-Korcsok E,Bagdy E,Hársing LG Jr,Sharp T,Hajós M

更新日期：2000-01-01 00:00:00