Brain mechanisms of proactive interference in working memory.

abstract：:The expression pattern of pannexin1, a gene coding for a protein that forms gap junction channels, was studied as both mRNA and protein in the CNS of adult mouse. Pannexin1 was widely expressed in the CNS by neuronal cell types but not glial cells, except for Bergmann glial cells of the cerebellar cortex. Cells positi...

journal_title：Neuroscience

authors： Zappalà A,Cicero D,Serapide MF,Paz C,Catania MV,Falchi M,Parenti R,Pantò MR,La Delia F,Cicirata F

更新日期：2006-08-11 00:00:00

abstract：:One of the most replicated findings has been that hippocampus volume is decreased in patients with major depressive disorder (MDD). Recent volumetric magnetic resonance imaging (MRI) studies suggest that localized differences in hippocampal volume may be more prominent than global differences. Preclinical and post-mor...

journal_title：Neuroscience

authors： Malykhin NV,Coupland NJ

更新日期：2015-11-19 00:00:00

abstract：:We revealed the structural features of astrocytes by means of light microscopy, confocal laser scanning microscopy and high voltage electron microscopy, and estimated their numerical densities in the mouse hippocampus. The high voltage electron microscope examinations of Golgi-impregnated astrocytes clearly disclosed ...

journal_title：Neuroscience

authors： Ogata K,Kosaka T

更新日期：2002-01-01 00:00:00

abstract：:To evaluate the potential for lipofectin-mediated central nervous system gene transfer, the plasmid coding for cholecystokinin was administered intracerebroventricularly to rats, which have congenital audiogenic seizures and high responses to peripheral electric stimulation-induced analgesia. Previous studies had show...

journal_title：Neuroscience

authors： Zhang LX,Li XL,Smith MA,Post RM,Han JS

更新日期：1997-03-01 00:00:00

abstract：:Synthesis of phosphatidylcholine, the most abundant brain membrane phosphatide, requires three circulating precursors: choline; a pyrimidine (e.g. uridine); and a polyunsaturated fatty acid. Supplementing a choline-containing diet with the uridine source uridine-5'-monophosphate (UMP) or, especially, with UMP plus the...

journal_title：Neuroscience

authors： Cansev M,Wurtman RJ

更新日期：2007-08-24 00:00:00

abstract：:Cerebral hypoxia may be the main component of cell damage caused by ischemia. Previous studies demonstrated a neuroprotective effect of early hyperbaric oxygen (HBO) treatment in various animal models of focal cerebral ischemia. Neuropathologic study showed that exposure of HBO may prevent cell death in ischemic corte...

journal_title：Neuroscience

authors： Lou M,Zhang H,Wang J,Wen SQ,Tang ZQ,Chen YZ,Yan WQ,Ding MP

更新日期：2007-05-11 00:00:00

abstract：:Acetylcholinesterase is released from both axon terminals and dendrites of nigrostriatal neurons. The relationship of this phenomenon to: (1) activation of receptors, and (2) firing rate, has been examined. In the first series of experiments, apomorphine or acetylcholine were infused into substantiae nigrae of urethan...

journal_title：Neuroscience

authors： Weston J,Greenfield SA

更新日期：1986-04-01 00:00:00

abstract：:Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by motor neuron loss and gliosis in the spinal cord, brain stem and cortex. The Notch signaling pathway has been reported to be dysfunctional in neurodegenerative diseases, including ALS. However, the exact mechanism is still uncle...

journal_title：Neuroscience

authors： Liu C,Li D,Lv C,Gao Z,Qi Y,Wu H,Tian Y,Guo Y

更新日期：2020-04-15 00:00:00

abstract：:Acute low back pain (LBP) is associated with differential changes in motor coordination of deep and superficial trunk muscles. Whether this is related to differential changes in excitability of descending corticomotor inputs remains unclear and was investigated in nine healthy individuals. Fine-wire i.m. electrodes we...

journal_title：Neuroscience

authors： Tsao H,Tucker KJ,Hodges PW

更新日期：2011-05-05 00:00:00

abstract：:Synaptic terminals of the habenulo-interpeduncular axons in rat interpeduncular nucleus are demonstrated by electron-microscopic autoradiography following [3H]leucine injection into the habenula. The endings are of two types, S and crest synapses. Previous descriptions of the S synapses based on indirect identificatio...

journal_title：Neuroscience

authors： Lenn NJ,Wong V,Hamill GS

更新日期：1983-06-01 00:00:00

abstract：:Hypoglycemia causes brain fuel deprivation, resulting in functional brain failure and brain death. It is a serious complication of insulin therapy in diabetic patients. A single intrafemoral dose of streptozotocin was administered to induce diabetes. Hypoglycemia was induced by appropriate doses of insulin s.c. in con...

journal_title：Neuroscience

authors： Joseph A,Antony S,Paulose CS

更新日期：2008-10-02 00:00:00

abstract：:Neuropathic pain resulting from spinal cord injury is often accompanied by maladaptive plasticity of the central nervous system, including the opioid receptor-rich periaqueductal gray (PAG). Evidence suggests that sensory signaling via the PAG is robustly modulated by dopamine D1- and D2-like receptors, but the effect...

journal_title：Neuroscience

authors： Voulalas PJ,Ji Y,Jiang L,Asgar J,Ro JY,Masri R

更新日期：2017-02-20 00:00:00

abstract：:Regular physical exercise has been described as a good strategy for prevention or reduction of musculoskeletal pain. The Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) has been investigated as a promising target for the control of inflammatory pain. Therefore, the aim of this study was to evaluate whether ac...

journal_title：Neuroscience

authors： de Azambuja G,Botasso Gomes B,Messias LHD,Aquino BM,Jorge CO,Manchado-Gobatto FB,Oliveira-Fusaro MCG

更新日期：2020-02-10 00:00:00

abstract：:The radioligands [3H]SCH 23390 and [3H]spiroperidol were used to label dopamine D1 and D2 receptors, respectively, in rat brain slices. Striatal sections were incubated in one of various concentrations of radioligand in the presence or absence of (+)-butaclamol and the resulting labeling was determined by liquid scint...

journal_title：Neuroscience

authors： Bardo MT,Hammer RP Jr

更新日期：1991-01-01 00:00:00

abstract：:Recently, the reports that sensory nerves contribute to induction and development of peripheral inflammation have been accumulating. Although neuropeptides have been thought to participate in modulation of inflammation, we supposed the involvement of cytokines. Interleukin-12 (IL-12) is a key regulator of cell-mediate...

journal_title：Neuroscience

authors： Hikawa N,Ishikawa Y,Takenaka T

更新日期：2004-01-01 00:00:00

abstract：:Probenecid has been used for decades to treat gout, and recent studies have revealed it is also a specific inhibitor of the pannexin-1 channel. It has been reported that the pannexin-1 channel is involved in ischemic injury. Here, we investigated the neuroprotective effect and the possible mechanisms of action of prob...

journal_title：Neuroscience

authors： Wei R,Wang J,Xu Y,Yin B,He F,Du Y,Peng G,Luo B

更新日期：2015-08-20 00:00:00

abstract：:Microglia are the prime cellular sources of reactive oxygen species (ROS) in the central nervous system (CNS). Chronic activation of microglia has been linked to aging-associated neurodegenerative diseases such as Alzheimer's disease (AD) and Parkinson's disease (PD) since they produce excessive amounts of ROS for a p...

journal_title：Neuroscience

authors： Rangarajan P,Karthikeyan A,Lu J,Ling EA,Dheen ST

更新日期：2015-12-17 00:00:00

abstract：:Our human visual system exploits spatiotemporal regularity to interpret incoming visual signals. With a dynamic stimulus sequence of four collinear bars (predictors) appearing consecutively toward the fovea, followed by a target bar with varying contrasts, we have previously found that this predictable spatiotemporal ...

journal_title：Neuroscience

authors： Roebuck H,Bourke P,Guo K

更新日期：2014-03-28 00:00:00

abstract：:Three structurally distinct groups of antagonists were used to test the hypothesis that integrin adhesion receptors play an essential role in consolidating (stabilizing) long term potentiation of the Schaffer collaterals in rat hippocampus. Comparisons were made of percent potentiation at antagonist-treated versus con...

journal_title：Neuroscience

authors： Chun D,Gall CM,Bi X,Lynch G

更新日期：2001-01-01 00:00:00

abstract：:Strong converging evidence indicates that the intermediate and medial part of the hyperstriatum ventrale (IMHV) of the chick forebrain is a site of recognition memory for the learning process of imprinting. Clathrin proteins have been implicated in synaptic plasticity. In the present study we demonstrate for the first...

journal_title：Neuroscience

authors： Solomonia RO,McCabe BJ,Jackson AP,Horn G

更新日期：1997-09-01 00:00:00

abstract：:Sixty-three cortically projecting basal forebrain neurons were identified in chloral hydrate anesthetized rats by antidromic activation from the cerebral cortex. Two subpopulations were noted: type I neurons exhibited two antidromic action potentials of constant latency and identical waveform in response to double pul...

journal_title：Neuroscience

authors： Reiner PB,Semba K,Fibiger HC,McGeer EG

更新日期：1987-02-01 00:00:00

abstract：:Neural activity varies continually from moment to moment. Such temporal variability (TV) has been highlighted as a functionally specific brain property playing a fundamental role in cognition. We sought to investigate the mechanisms involved in TV changes between two basic behavioral states, namely having the eyes ope...

journal_title：Neuroscience

authors： Qin P,Duncan NW,Chen DY,Chen CJ,Huang LK,Huang Z,Lin CE,Wiebking C,Yang CM,Northoff G,Lane TJ

更新日期：2018-05-21 00:00:00

abstract：:In an attempt to improve the survival of implanted dopamine cells, we have readdressed the optimal embryonic donor age for dopamine grafts. In a rat model of Parkinson's disease, animals with unilateral 6-hydroxydopamine lesions of the median forebrain bundle received dopamine-rich ventral mesencephalic grafts derived...

journal_title：Neuroscience

authors： Torres EM,Monville C,Gates MA,Bagga V,Dunnett SB

更新日期：2007-06-08 00:00:00

abstract：:The tight junctions found between cerebral vascular endothelial cells form the basis of the blood-brain barrier. Breakdown of the blood-brain barrier is a feature of a variety of CNS pathologies that are characterized by extensive leucocyte recruitment, such as multiple sclerosis and stroke. The molecular mechanisms a...

journal_title：Neuroscience

authors： Bolton SJ,Anthony DC,Perry VH

更新日期：1998-10-01 00:00:00

abstract：:Ponto-geniculo-occipital waves and rapid eye movements (eye saccades) are two prominent phasic events of paradoxical sleep which occur in conjunction. Although they have been studied intensively, the neuronal link between these two events is still poorly understood. On the basis of our previous results, combining brai...

journal_title：Neuroscience

authors： Vanni-Mercier G,Debilly G

更新日期：1998-09-01 00:00:00

abstract：:The nucleus of the solitary tract is the site of termination of primary afferent fibers running in the facial, glossopharyngeal and vagus nerves. The present study was performed to map the distribution of glutamatergic axons terminals in the rat nucleus of the solitary tract using immunodetection of vesicular glutamat...

journal_title：Neuroscience

authors： Lachamp P,Crest M,Kessler JP

更新日期：2006-01-01 00:00:00

abstract：:Peripheral nerve injury in a limb usually causes functional reorganization of the contralateral motor cortex. However, a dynamic process of the novel transhemispheric functional reorganization in the motor cortex was found in adult rats after transferring the seventh cervical nerve root from the contralateral healthy ...

journal_title：Neuroscience

authors： Lou L,Shou T,Li Z,Li W,Gu Y

更新日期：2006-01-01 00:00:00

abstract：:Cortical microcircuitry plays a pivotal role in encoding sensory information reaching the cortex. However, the fundamental knowledge concerning the mechanisms that govern feature-encoding by these sub-networks is still sparse. Here, we show through multi-electrode recordings in V1 of conventionally prepared anesthetiz...

journal_title：Neuroscience

authors： Bharmauria V,Bachatene L,Cattan S,Rouat J,Molotchnikoff S

更新日期：2014-05-30 00:00:00

abstract：:Kinetic properties of synaptic depression were analysed for excitatory postsynaptic potentials in neuron number 3 in the right pallial ganglion of Helix pomatia. It was observed that long-term depression did not only suppress the amplitudes of excitatory postsynaptic potentials but also changed the kinetics of short-t...

journal_title：Neuroscience

authors： Christoffersen GR,Schilhab TS

更新日期：1996-08-01 00:00:00

abstract：:Nitric oxide synthase is the biosynthetic enzyme for the free radical neurotransmitter nitric oxide. Using an affinity-purified antiserum, nitric oxide synthase was found to be localized to peripheral ocular nerve fibers, related cranial ganglia, and the retina of the rat. In the eye, nitric oxide synthase-like immuno...

journal_title：Neuroscience

authors： Yamamoto R,Bredt DS,Snyder SH,Stone RA

更新日期：1993-05-01 00:00:00