Atropine-sensitive hippocampal θ oscillations are mediated by Cav2.3 R-type Ca²⁺ channels.

abstract：:The topographic distribution of cells containing monoamine oxidase, the enzyme which deaminates amines, was studied in the cat medulla oblongata. By means of enzyme histochemistry using a new coupled peroxidation method, monoamine oxidase activity was demonstrated in the somata, dendrites and fibers. Type A monoamine ...

journal_title：Neuroscience

authors： Kitahama K,Kimura H,Maeda T,Jouvet M

更新日期：1987-03-01 00:00:00

abstract：:Dopamine and endocannabinoids are neurotransmitters known to play a role in the activity of the basal ganglia motor circuit. While a number of studies have demonstrated functional interactions between type 1 cannabinoid (CB1) receptors and dopaminergic systems, we still lack detailed neuroanatomical evidence to explai...

journal_title：Neuroscience

authors： Julian MD,Martin AB,Cuellar B,Rodriguez De Fonseca F,Navarro M,Moratalla R,Garcia-Segura LM

更新日期：2003-01-01 00:00:00

abstract：:Free radicals have been implicated in a number of pathological conditions. To evaluate the neurophysiological consequences of free radical exposure, slices of hippocampus isolated from guinea-pigs were exposed to hydrogen peroxide which reacts with tissue iron to generate hydroxyl free radicals. Long-term potentiation...

journal_title：Neuroscience

authors： Pellmar TC,Hollinden GE,Sarvey JM

更新日期：1991-01-01 00:00:00

abstract：:Sensory experience has a profound effect on neocortical neurons. Passive stimulation of whiskers or sensory deprivation from whiskers can induce long-lasting changes in neuronal responses or modify the receptive field in adult animals. We recorded barrel cortical neurons in urethane-anesthetized rats in layers 2/3 or ...

journal_title：Neuroscience

authors： Barros-Zulaica N,Castejon C,Nuñez A

更新日期：2014-12-05 00:00:00

abstract：:Having provided an anatomical description of the efferent projections of the dorsal midbrain anticonvulsant zone [Shehab S. et al. (1995) Neuroscience 65, 681-695], our purpose in the present study was to establish which outputs from this region are responsible for mediating the anticonvulsant and behavioural properti...

journal_title：Neuroscience

authors： Shehab S,Simkins M,Dean P,Redgrave P

更新日期：1995-04-01 00:00:00

abstract：:Free intracellular calcium concentration ([Ca2+]in) was recorded at 22 degrees C by means of Indo-1 or Fura-2 single-cell microfluorometry in cultured dorsal root ganglion neurons obtained from neonatal rats. The resting [Ca2+]in in dorsal root ganglion neurons was 73 +/- 21 nM (mean +/- S.D., n = 94). Fast applicatio...

journal_title：Neuroscience

authors： Usachev Y,Shmigol A,Pronchuk N,Kostyuk P,Verkhratsky A

更新日期：1993-12-01 00:00:00

abstract：:The pattern of expression of p75, the low affinity nerve growth factor receptor, in the adult rat cerebellum and its fate after a traumatic lesion were analysed using immunohistochemical localization of this receptor. A subset of Purkinje cells was immunoreactive for low affinity nerve growth factor receptor in the in...

journal_title：Neuroscience

authors： Dusart I,Morel MP,Sotelo C

更新日期：1994-11-01 00:00:00

abstract：:Serotonergic systems are thought to play an important role in control of motor activity and emotional states. We used a fear-potentiated startle paradigm to investigate the effects of a motor-eliciting stimulus in the presence or absence of induction of an acute fear state on serotonergic neurons in the dorsal raphe n...

journal_title：Neuroscience

authors： Spannuth BM,Hale MW,Evans AK,Lukkes JL,Campeau S,Lowry CA

更新日期：2011-04-14 00:00:00

abstract：:Human acidic fibroblast growth factor (haFGF), a neurotrophin-like growth factor in the brain, plays important roles in the development, differentiation and regeneration of brain neurons, which makes it potential to treat Alzheimer's disease (AD). In this study, haFGF(14-154) and TAT-haFGF(14-154) (haFGF(14-154) fused...

journal_title：Neuroscience

authors： Lou G,Zhang Q,Xiao F,Xiang Q,Su Z,Zhang L,Yang P,Yang Y,Zheng Q,Huang Y

更新日期：2012-10-25 00:00:00

abstract：:Characteristics of atrial natriuretic peptide receptors were determined in cultured mouse spinal cord cells. Saturation and competition experiments demonstrated the presence of a single class of atrial natriuretic peptide binding sites with high affinity (KD = 0.054 nM) and a density of 1.92 fmoles/10(6) cells. A simi...

journal_title：Neuroscience

authors： Simonnet G,Allard M,Legendre P,Gabrion J,Vincent JD

更新日期：1989-01-01 00:00:00

abstract：:Physiological studies suggest visceral spinal afferents are generally small diameter, unmyelinated C-fibers or myelinated Adelta-fibers, but little is known about the size and chemical phenotypes of visceral sensory neurons supplying the small intestine. This study examines the size and expression patterns of transien...

journal_title：Neuroscience

authors： Tan LL,Bornstein JC,Anderson CR

更新日期：2008-10-02 00:00:00

abstract：:To elucidate the role and the mechanism of action of nerve growth factor in the adult central nervous system, we investigated the localization of nerve growth factor-like immunoreactivity in adult rat brain, both quantitatively and immunohistochemically, using polyclonal anti-nerve growth factor immunoglobulin G. We r...

journal_title：Neuroscience

authors： Nishio T,Furukawa S,Akiguchi I,Oka N,Ohnishi K,Tomimoto H,Nakamura S,Kimura J

更新日期：1994-05-01 00:00:00

abstract：:Brainstem networks generating the respiratory rhythm in lampreys are still not fully characterized. In this study, we described the patterns of respiratory activities and we identified the general location of underlying neural networks. In a semi-intact preparation including the brain and gills, rhythmic discharges we...

journal_title：Neuroscience

authors： Martel B,Guimond JC,Gariépy JF,Gravel J,Auclair F,Kolta A,Lund JP,Dubuc R

更新日期：2007-08-10 00:00:00

abstract：:Dexamethasone (Dex) provides neuroprotection against subsequent hypoxia ischemia (HI) in newborn rats, but the mechanism of this neuroprotection is not well understood. It is known that vascular endothelial growth factor A (VEGF) has neuroprotective effects. The objective of this study was to evaluate the role of the ...

journal_title：Neuroscience

authors： Feng Y,Rhodes PG,Bhatt AJ

更新日期：2011-04-14 00:00:00

abstract：:This study examined the age-related subsequent memory effect (SME) in perceptual and semantic encoding using event-related potentials (ERPs). Seventeen younger adults and 17 older adults studied a series of Chinese characters either perceptually (by inspecting orthographic components) or semantically (by determining w...

journal_title：Neuroscience

authors： Kuo MC,Liu KP,Ting KH,Chan CC

更新日期：2014-03-07 00:00:00

abstract：:Although numerous studies have demonstrated the neurotrophic capacity of gp130 cytokines, it remains unclear whether endogenously expressed cytokines actually function in a direct neuromodulatory manner. Therefore, using the lithium-pilocarpine status epilepticus model, we performed a detailed in situ hybridization ti...

journal_title：Neuroscience

authors： Rosell DR,Nacher J,Akama KT,McEwen BS

更新日期：2003-01-01 00:00:00

abstract：:The activity of 62 antidromically identified prepositus hypoglossi neurons was recorded in 10 alert cats during spontaneous, vestibular or visually induced eye movements. Neurons were antidromically activated from stimulating electrodes implanted in the ipsilateral medial longitudinal fasciculus (n = 24), the ipsilate...

journal_title：Neuroscience

authors： Delgado-García JM,Vidal PP,Gómez C,Berthoz A

更新日期：1989-01-01 00:00:00

abstract：:It was demonstrated with autoradiographic methods that a tract of thin fibers, which is for the most part distinct from the brachium conjunctivum and its crossed descending limb, can be followed from the cerebellar nuclei to the inferior olive. Neurons from all regions of the interposed and dentate nuclei contribute t...

journal_title：Neuroscience

authors： Legendre A,Courville J

更新日期：1987-06-01 00:00:00

abstract：:The central nervous system expresses its function in natural frames of reference. A most conspicuous feature of such frames is their non-orthogonality. Gaze stabilization and, in particular, the sensorimotor transformations performed by the vestibulo-ocular reflex, are prime examples of such general coordinate transfo...

journal_title：Neuroscience

authors： Ostriker G,Pellionisz A,Llinás R

更新日期：1985-02-01 00:00:00

abstract：:The dorsal hippocampus (DH) is a structure of the limbic system that is involved in emotional, learning and memory processes. There is evidence indicating that the DH modulates cardiovascular correlates of behavioral responses to stressful stimuli. Acute restraint stress (RS) is an unavoidable stress situation that ev...

journal_title：Neuroscience

authors： Moraes-Neto TB,Scopinho AA,Biojone C,Corrêa FM,Resstel LB

更新日期：2014-01-31 00:00:00

abstract：:Small (SK) and intermediate (IK) conductance calcium-activated potassium channels are candidate ion channels for the regulation of excitability in nociceptive neurones. We have used unique peptide-directed antisera to describe the immunocytochemical distribution of the known isoforms of these ion channels in dorsal ro...

journal_title：Neuroscience

authors： Mongan LC,Hill MJ,Chen MX,Tate SN,Collins SD,Buckby L,Grubb BD

更新日期：2005-01-01 00:00:00

abstract：:N-Methyl-D-aspartate receptors are thought to be involved in synaptic signaling within the hypothalamo-neurohypophysial system, but the extent and nature of their involvement has not been determined. In this study, in the rat, we evaluated the effect of hyperosmotic stimulation on the N-methyl-D-aspartate receptor sub...

journal_title：Neuroscience

authors： Decavel C,Curras MC

更新日期：1997-05-01 00:00:00

abstract：:Fetal striatal transplantation has emerged as a new therapeutic strategy in Huntington's disease (HD). Hypoxia is one of the microenvironmental stress conditions to which fetal tissue is exposed as soon as it is isolated and transplanted into the diseased host brain. Mechanisms that support neuroblast survival and rep...

journal_title：Neuroscience

authors： Ambrosini S,Sarchielli E,Comeglio P,Porfirio B,Gallina P,Morelli A,Vannelli GB

更新日期：2015-03-19 00:00:00

abstract：:In order to investigate the basic cellular mechanisms involved in neuronal interactions within the striatum, we prepared a primary striatal cell culture from rat fetal brain in chemically defined medium. Using morphological and whole-cell recording methods, we observed that an intensive neuritic elongation with a prog...

journal_title：Neuroscience

authors： Kowalski C,Crest M,Vuillet J,Pin T,Gola M,Nieoullon A

更新日期：1995-02-01 00:00:00

abstract：:Earlier studies have implicated brain-derived neurotrophic factor in stress and in the mechanism of action of antidepressants. It has been shown that antidepressants upregulate, whereas corticosterone downregulates, brain-derived neurotrophic factor expression in rat brain. Whether various classes of antidepressants r...

journal_title：Neuroscience

authors： Dwivedi Y,Rizavi HS,Pandey GN

更新日期：2006-01-01 00:00:00

abstract：:Serotonin (5-HT) and norepinephrine (NE) have been implicated in the mediation of endogenous analgesic mechanisms via the descending inhibitory pain pathway in the brain, and dysfunction in both the 5-HT and NE systems has been suggested as an etiology of fibromyalgia (FM). Given that 5-HT reuptake inhibition in the b...

journal_title：Neuroscience

authors： Murai N,Fushiki H,Honda S,Murakami Y,Iwashita A,Irie M,Tamura S,Nagakura Y,Aoki T

更新日期：2015-03-19 00:00:00

abstract：:We have re-examined in the rat the nuclear localization of the medullary catecholamine-containing cell groups (A1 and A2) and their relation to the vagal motor nuclei using a double labeling method. The vagal nuclei were defined by the retrograde transport of horseradish peroxidase applied to the cervical vagus, and n...

journal_title：Neuroscience

authors： Ritchie TC,Westlund KN,Bowker RM,Coulter JD,Leonard RB

更新日期：1982-06-01 00:00:00

abstract：:Rett syndrome (RTT), a disorder caused almost exclusively by mutations in the X-linked gene, MECP2, has a phenotype thought to be primarily of neurological origin. Disruption of Mecp2 in mice results in a prominent RTT-like phenotype. One of the consequences of MeCP2 absence in the brain is altered functional and stru...

journal_title：Neuroscience

authors： Weng SM,McLeod F,Bailey ME,Cobb SR

更新日期：2011-04-28 00:00:00

abstract：:Cortical auditory evoked potential (CAEP) testing, a non-invasive technique, is widely employed to study auditory brain development. The aim of this study was to investigate the development of the auditory electrophysiological signal without addressing specific abilities such as speech or music discrimination. We were...

journal_title：Neuroscience

authors： Lippé S,Martinez-Montes E,Arcand C,Lassonde M

更新日期：2009-12-15 00:00:00

abstract：:Obesity may result from dysfunction of the reward system, especially in the nucleus accumbens (Acb). Based on this hypothesis, many researchers have tested the effect of high-frequency stimulation (HFS) of the Acb shell (Acb-Sh) and/or core (Acb-Co) on ingestive behaviors, but few studies have explored the possible me...

journal_title：Neuroscience

authors： Wei N,Wang Y,Wang X,He Z,Zhang M,Zhang X,Pan Y,Zhang J,Qin Z,Zhang K

更新日期：2015-08-20 00:00:00