Abstract:
:The topographic distribution of cells containing monoamine oxidase, the enzyme which deaminates amines, was studied in the cat medulla oblongata. By means of enzyme histochemistry using a new coupled peroxidation method, monoamine oxidase activity was demonstrated in the somata, dendrites and fibers. Type A monoamine oxidase, inhibited by clorgyline but not deprenyl, were localized in the cells distributed in the ventrolateral and dorsomedial medulla where catecholaminergic neurons are present. Type B monoamine oxidase-positive cell bodies were identified in the regions containing serotonergic neurons. Furthermore, we found an intense activity of type A monoamine oxidase in many cells of the dorsal motor nucleus of the vagus of the rostrocaudal extent, and more rostrally in the nucleus parvocellularis where few or no aminergic neurons have been described.
journal_name
Neurosciencejournal_title
Neuroscienceauthors
Kitahama K,Kimura H,Maeda T,Jouvet Mdoi
10.1016/0306-4522(87)90257-0subject
Has Abstractpub_date
1987-03-01 00:00:00pages
991-9issue
3eissn
0306-4522issn
1873-7544pii
0306-4522(87)90257-0journal_volume
20pub_type
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