Chronic anabolic-androgenic steroid treatment during adolescence increases anterior hypothalamic vasopressin and aggression in intact hamsters.

abstract：OBJECTIVE:Telomere shortening, a biomarker of cellular aging, has been associated with aging-related diseases. While psychological stress has been implicated in the process of telomere shortening, associations with activity of physiological stress systems have remained elusive. We studied whether leukocyte telomere len...

journal_title：Psychoneuroendocrinology

authors： Savolainen K,Eriksson JG,Kajantie E,Lahti J,Räikkönen K

更新日期：2015-03-01 00:00:00

abstract：:The rat forced swim test (FST) is a model that is used extensively as a screening test for antidepressant activity. It has previously been reported that thorough analysis of behaviour in this model reveals two distinct types of active response - climbing and swimming - and that these are separately evoked by re-uptake...

journal_title：Psychoneuroendocrinology

authors： Kelliher P,Kelly JP,Leonard BE,Sánchez C

更新日期：2003-04-01 00:00:00

abstract：:The role of corticosteroids in brain aging remains a controversial issue. Conceivably, if corticosteroids levels are increased in the aged brain, neuronal function might be altered. For instance, GABA-mediated synaptic events, spike accommodation and afterhyperpolarizing potentials (AHPs) might be modified. Our electr...

journal_title：Psychoneuroendocrinology

authors： Lamour Y,Potier B,Jouvenceau A,Billard JM,Dutar P

更新日期：1997-01-01 00:00:00

abstract：CONTEXT:Affective symptoms are poorly understood in polycystic ovary syndrome (PCOS). Clinical signs of hyperandrogenism and high serum androgens are key features in PCOS, and women with PCOS are more likely to be overweight or obese, as well as insulin resistant. Further, PCOS is associated with high sympathetic nerve...

journal_title：Psychoneuroendocrinology

authors： Jedel E,Gustafson D,Waern M,Sverrisdottir YB,Landén M,Janson PO,Labrie F,Ohlsson C,Stener-Victorin E

更新日期：2011-11-01 00:00:00

abstract：:The current study investigates the effect of a single episode of acute social stress on healthy children's processing of facial expressions of emotion. Healthy nine- and ten-year-old boys (N=39) underwent either a standardized psychosocial laboratory stressor (the Trier Social Stress Test for Children) or a control co...

journal_title：Psychoneuroendocrinology

authors： Chen FS,Schmitz J,Domes G,Tuschen-Caffier B,Heinrichs M

更新日期：2014-02-01 00:00:00

abstract：:Opioid administration in males results in opioid-induced androgen deficiency which persists throughout the treatment. In adults, this quickly reverses once opioid administration is suspended. However, less is known about the duration of the effect following drug discontinuation in adolescents. Given the significant im...

journal_title：Psychoneuroendocrinology

authors： Hofford RS,Wellman PJ,Eitan S

更新日期：2011-06-01 00:00:00

abstract：:The evolution of the autonomic nervous system provides an organizing principle to interpret the adaptive significance of mammalian affective processes including courting, sexual arousal, copulation, and the establishment of enduring social bonds. According to the Polyvagal Theory (Porges, 1995, 1996, 1997), the well-d...

journal_title：Psychoneuroendocrinology

authors： Porges SW

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND:Subliminal intragastric fatty acid infusion attenuates subjective and brain responses to negative emotion induction. However, the underlying gut-brain signaling mechanisms remain unclear, and it is unknown whether such effect equally applies to positive emotion. OBJECTIVE:We aimed to investigate the interac...

journal_title：Psychoneuroendocrinology

authors： Zhao D,Boey L,Weltens N,Biesiekierski JR,Iven J,Depoortere I,Tack J,Van Oudenhove L

更新日期：2019-10-01 00:00:00

abstract：:Ghrelin is a 28-amino-acid peptide hormone, first described in 1999 and broadly expressed in the organism. As the only known orexigenic hormone secreted in the periphery, it increases hunger and appetite, promoting food intake. Ghrelin has also been shown to be involved in various physiological processes being regulat...

journal_title：Psychoneuroendocrinology

authors： Wittekind DA,Kluge M

更新日期：2015-02-01 00:00:00

abstract：:The second generation antipsychotics clozapine and olanzapine are known to cause weight gain. However, only clozapine is associated with drug-induced fever. Cytokines have been linked to the induction of both weight gain and drug-induced fever. We investigated these potential side effects of clozapine and olanzapine a...

journal_title：Psychoneuroendocrinology

authors： Kluge M,Schuld A,Schacht A,Himmerich H,Dalal MA,Wehmeier PM,Hinze-Selch D,Kraus T,Dittmann RW,Pollmächer T

更新日期：2009-01-01 00:00:00

abstract：:Previous studies have shown that the regulation of hunger and satiety is accompanied by coordinate changes in cortical excitability. Starved subjects show a transient negative shift in the scalp-recorded cortical direct current (DC-)potential in the beginning of eating, indicating increased cortical excitability. With...

journal_title：Psychoneuroendocrinology

authors： Hallschmid M,Gais S,Meinert S,Born J

更新日期：2003-05-01 00:00:00

abstract：:The enzyme telomerase, through its influence on telomere length, is associated with health and mortality. Four pioneering randomized control trials, including a total of 190 participants, provided information on the effect of mindfulness meditation on telomerase. A meta-analytic effect size of d=0.46 indicated that mi...

journal_title：Psychoneuroendocrinology

authors： Schutte NS,Malouff JM

更新日期：2014-04-01 00:00:00

abstract：:Orexigenic hormones are a group of hormones that can up-regulate appetite. Current studies have shown that orexigenic hormones also play important roles in stress responses and may be implicated in regulation of fear memory. However, these conclusions lack evidence from human studies. In this study, we examined associ...

journal_title：Psychoneuroendocrinology

authors： Li G,Zhang K,Wang L,Cao C,Fang R,Liu P,Luo S,Liberzon I

更新日期：2019-02-01 00:00:00

abstract：:Inconsistent findings have been found on the relation between oxytocin levels and psychopathy or callous-unemotional (CU) traits in humans, potentially because the role of trauma in oxytocin secretion and the distinction between primary and secondary psychopathy have been overlooked so far. Primary psychopathy has a s...

journal_title：Psychoneuroendocrinology

authors： Fragkaki I,Verhagen M,van Herwaarden AE,Cima M

更新日期：2019-04-01 00:00:00

abstract：:There is limited information on the relation between age-related changes in pituitary-gonadal function and sleep physiology in older men. In this cross-sectional study of 67 healthy volunteers free from sleep complaints, aged 45-75 yr, we (1) assessed peak fluctuations and hourly variations in plasma testosterone, LH ...

journal_title：Psychoneuroendocrinology

authors： Schiavi RC,White D,Mandeli J

更新日期：1992-11-01 00:00:00

abstract：:Overactivity of the hypothalamic-pituitary-adrenal (HPA) axis has been frequently described in depression. Due to the closed-loop nature of the HPA axis, one possible cause of this overactivity may be a defect in negative feedback regulation, in particular an abnormality of the glucocorticoid receptor (GR). In the pre...

journal_title：Psychoneuroendocrinology

authors： Cotter PA,Mulligan OF,Landau S,Papadopoulos A,Lightman SL,Checkley SA

更新日期：2002-05-01 00:00:00

abstract：:Sensitization is defined as a non-associative learning process occurring when repeated administrations of a stimulus result in a progressive amplification of a response (Shettleworth, 2010). The purpose of this review paper is to discuss whether brain sensitization is helpful in common health problems in man. The pape...

journal_title：Psychoneuroendocrinology

authors： Ursin H

更新日期：2014-04-01 00:00:00

abstract：INTRODUCTION:Individuals who are exposed to a traumatic event are at increased risk of developing psychiatric disorders such as posttraumatic stress disorder (PTSD). Studies have shown that increased amygdala activity is frequently found in patients with PTSD. In addition, pre-trauma glucocorticoid receptor (GR) number...

journal_title：Psychoneuroendocrinology

authors： Geuze E,van Wingen GA,van Zuiden M,Rademaker AR,Vermetten E,Kavelaars A,Fernández G,Heijnen CJ

更新日期：2012-11-01 00:00:00

abstract：:Hypothalamo-pituitary functions were examined in thirteen children with behavioral disorders (six with hyperkinesia, four with autism, two with tic and one with schizophrenia) before and during treatment with pimozide, an antidopaminergic drug. The mean (+/- S.E.M.) basal serum PRL level (24.5 +/- 4.2 ng/ml) during pi...

journal_title：Psychoneuroendocrinology

authors： Suwa S,Naruse H,Ohura T,Tsuruhara T,Takesada M,Yamazaki K,Mikuni M

更新日期：1984-01-01 00:00:00

abstract：OBJECTIVE:The main aim of this exploratory study was to assess whether salivary α-amylase (sAA) and salivary cortisol levels would be positively modulated by sleep-focused mind-body interventions in female and male cancer survivors. METHODS:We conducted a randomized controlled trial in which 57 cancer survivors with s...

journal_title：Psychoneuroendocrinology

authors： Lipschitz DL,Kuhn R,Kinney AY,Donaldson GW,Nakamura Y

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Nightmares and insomnia in PTSD are hallmark symptoms, yet poorly understood in comparison to the advances toward a biological framework for the disorder. According to polysomnography (PSG), only minor changes in sleep architecture were described. This warrants alternative methods for assessing sleep regulat...

journal_title：Psychoneuroendocrinology

authors： van Liempt S,Arends J,Cluitmans PJ,Westenberg HG,Kahn RS,Vermetten E

更新日期：2013-01-01 00:00:00

abstract：:A prenatal hypothyroid state is associated with behavioral abnormalities in adulthood. Wistar Kyoto (WKY) rats exhibit hypothyroidism and increased depressive and anxiety-like behaviors. Thus, the WKY could illuminate the mechanisms by which the reversal of developmental hypothyroidism in humans and animals results in...

journal_title：Psychoneuroendocrinology

authors： Shukla PK,Sittig LJ,Andrus BM,Schaffer DJ,Batra KK,Redei EE

更新日期：2010-07-01 00:00:00

abstract：:The relationship between stress and changes in insulin levels, plasma ratio of tryptophan to other large neutral amino acids (LNAAs), mood, and food intake was investigated in women taking monophasic oral contraceptives containing progestagens. Subjects experiencing high levels of stress displayed significant decrease...

journal_title：Psychoneuroendocrinology

authors： Tuiten A,Panhuysen G,Koppeschaar H,Fekkes D,Pijl H,Frölich M,Krabbe P,Everaerd W

更新日期：1995-01-01 00:00:00

abstract：:We injected ovariectomized female rats with estrogen and progesterone. Some of the injection regimens used are known to induce estrus, while other do not. The effects of these treatments on operant behavior were evaluated. Operant behavior was maintained under a reinforcement schedule, one segment of which involved ex...

journal_title：Psychoneuroendocrinology

authors： Rodriguez-Sierra JF,Howard JL,Pollard GT,Hendricks SE

更新日期：1984-01-01 00:00:00

abstract：:Attachment-based parenting interventions have shown positive effects on early cortisol regulation, a key biomarker. Evaluations to date have focused on diurnal cortisol production in high-risk infants. It is important to understand whether attachment-based intervention may also improve stress-induced cortisol producti...

journal_title：Psychoneuroendocrinology

authors： Berlin LJ,Martoccio TL,Bryce CI,Jones Harden B

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:Although the linkage between psychological stress and cortisol is believed to mediate the association of stress with health outcomes, several studies have been unable to demonstrate this association. We suggest this inability may be a consequence of limitations in the measurement approach and/or reliance on ...

journal_title：Psychoneuroendocrinology

authors： Lazarides C,Ward EB,Buss C,Chen WP,Voelkle MC,Gillen DL,Wadhwa PD,Entringer S

更新日期：2020-11-01 00:00:00

abstract：INTRODUCTION:During pregnancy, maternal stressors cause changes in both maternal and fetal HPA axes. We therefore investigated the impact of maternal non chronic and chronic stress on fetal glucose metabolism and growth, and serum levels of cortisol in the fetus. MATERIALS AND METHODS:Normal weight pregnant women (n =...

journal_title：Psychoneuroendocrinology

authors： Valsamakis G,Papatheodorou D,Chalarakis N,Manolikaki M,Margeli A,Papassotiriou I,Barber TM,Kumar S,Kalantaridou S,Mastorakos G

更新日期：2020-04-01 00:00:00

abstract：:Attention-deficit/hyperactivity disorder (ADHD) is one of the most common child psychiatric disorders. Previous studies have reported a blunted cortisol response to challenging situations and a decreased cortisol awakening response (CAR) in children with ADHD. As ADHD often is comorbid with oppositional defiant disord...

journal_title：Psychoneuroendocrinology

authors： Freitag CM,Hänig S,Palmason H,Meyer J,Wüst S,Seitz C

更新日期：2009-08-01 00:00:00

abstract：:Cognitive decline in old age is not universal or inevitable. Associations have been observed with neuroendocrine function, but the relevance of other physiological processes is unclear. We predicted that impairment of memory in an ageing population would be related to the dysregulation of neuroendocrine and cardiovasc...

journal_title：Psychoneuroendocrinology

authors： Wright CE,Kunz-Ebrecht SR,Iliffe S,Foese O,Steptoe A

更新日期：2005-10-01 00:00:00

abstract：:Deficient facial emotion recognition has been suggested to underlie aggression in individuals with antisocial personality disorder (ASPD). As the neuropeptide oxytocin (OT) has been shown to improve facial emotion recognition, it might also exert beneficial effects in individuals providing so much harm to the society....

journal_title：Psychoneuroendocrinology

authors： Timmermann M,Jeung H,Schmitt R,Boll S,Freitag CM,Bertsch K,Herpertz SC

更新日期：2017-11-01 00:00:00