Synaptic functions in the aged rat hippocampus: a target for corticosteroids?

abstract：:The present study examines the hypothesis that exposure to anabolic-androgenic steroids (AAS) during adolescent development predisposes hamsters to heightened levels of aggressive behavior by influencing the anterior hypothalamic-arginine vasopressin (AH-AVP) neural system. To test this, adolescent male hamsters (Meso...

journal_title：Psychoneuroendocrinology

authors： Harrison RJ,Connor DF,Nowak C,Nash K,Melloni RH Jr

更新日期：2000-05-01 00:00:00

abstract：:Sustained abnormalities of glucocorticoid levels have been associated with neuropsychiatric illnesses such as major depression, posttraumatic stress disorder (PTSD), panic disorder, and obsessive compulsive disorder. The pathophysiological effects of glucocorticoids may depend not only on the amount of glucocorticoid ...

journal_title：Psychoneuroendocrinology

authors： Pekary AE,Sattin A,Blood J,Furst S

更新日期：2008-10-01 00:00:00

abstract：:In the field of depression, inflammation-associated depression stands up as an exception since its causal factors are obvious and it is easy to mimic in an animal model. In addition, quasi-experimental studies can be carried out in patients who are treated chronically with recombinant cytokines for a medical condition...

journal_title：Psychoneuroendocrinology

authors： Dantzer R,O'Connor JC,Lawson MA,Kelley KW

更新日期：2011-04-01 00:00:00

abstract：:Diabetes is a highly prevalent, chronic disease that requires ongoing, multi-specialty medical care combined with patient self-management, family support, and education to prevent or delay end-organ morbidity and mortality. There is clearly an increased prevalence of major depressive disorder, a relatively common and ...

journal_title：Psychoneuroendocrinology

authors： Rustad JK,Musselman DL,Nemeroff CB

更新日期：2011-10-01 00:00:00

abstract：:Cognitive impairment has long been recognized as central to the abnormalities that occur in schizophrenia, since neurocognitive deficits are predictive of a number of outcome indices, and they pose a significant obstacle to any attempts at social rehabilitation. This raises the possibility that treatments producing im...

journal_title：Psychoneuroendocrinology

authors： Kasper S,Resinger E

更新日期：2003-01-01 00:00:00

abstract：:The intraperitoneal (i.p.) injection of ACTH 1-24 (0.2 microgram/kg), lysine--vasopressin (10.0 micrograms/kg) or epinephrine HCl (5.0 micrograms/kg) shortly after training or prior to testing caused memory facilitation of a step-down inhibitory avoidance task in rats, acquired with low intensity training footshocks (...

journal_title：Psychoneuroendocrinology

authors： Izquierdo I,Dias RD

更新日期：1985-01-01 00:00:00

abstract：:Functional genomics strategies have been slow to penetrate research on human stress and coping, but recent conceptual advances have yielded a raft of new findings relating social and psychological conditions to broad alterations in human gene expression. This article reviews the field of human stress genomics, analyze...

journal_title：Psychoneuroendocrinology

authors： Cole SW

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:Stress reducing effects of Taiji, a mindful and gentle form of body movement, have been reported in previous studies, but standardized and controlled experimental studies are scarce. The present study investigates the effect of regular Taiji practice on psychobiological stress response in healthy men and wom...

journal_title：Psychoneuroendocrinology

authors： Nedeljkovic M,Ausfeld-Hafter B,Streitberger K,Seiler R,Wirtz PH

更新日期：2012-08-01 00:00:00

abstract：:Orexigenic hormones are a group of hormones that can up-regulate appetite. Current studies have shown that orexigenic hormones also play important roles in stress responses and may be implicated in regulation of fear memory. However, these conclusions lack evidence from human studies. In this study, we examined associ...

journal_title：Psychoneuroendocrinology

authors： Li G,Zhang K,Wang L,Cao C,Fang R,Liu P,Luo S,Liberzon I

更新日期：2019-02-01 00:00:00

abstract：INTRODUCTION:During pregnancy, maternal stressors cause changes in both maternal and fetal HPA axes. We therefore investigated the impact of maternal non chronic and chronic stress on fetal glucose metabolism and growth, and serum levels of cortisol in the fetus. MATERIALS AND METHODS:Normal weight pregnant women (n =...

journal_title：Psychoneuroendocrinology

authors： Valsamakis G,Papatheodorou D,Chalarakis N,Manolikaki M,Margeli A,Papassotiriou I,Barber TM,Kumar S,Kalantaridou S,Mastorakos G

更新日期：2020-04-01 00:00:00

abstract：:Many sex differences can be found in the expression of aggression and parental nurturing behaviors. It is important to determine if these are modulated by prenatal conditions. Here, using assisted reproduction technologies, we generated females that were (mixed-sex) or were not (same-sex) exposed to males during fetal...

journal_title：Psychoneuroendocrinology

authors： Sugawara A,Pearson BL,Blanchard DC,Ward MA

更新日期：2012-03-01 00:00:00

abstract：OBJECTIVE:Individual differences in sensitivity to cyclical changes in ovarian steroids estradiol (E2) and progesterone (P4) have been implicated in the pathophysiology of menstrually related mood disorder (MRMD). However, no prospective studies have investigated psychosocial risk factors for sensitivity to hormone eff...

journal_title：Psychoneuroendocrinology

authors： Eisenlohr-Moul TA,Rubinow DR,Schiller CE,Johnson JL,Leserman J,Girdler SS

更新日期：2016-05-01 00:00:00

abstract：:Inflammation, which may be present in a subgroup of individuals with major depressive disorder (MDD), activates the kynurenine metabolic pathway to produce kynurenine metabolites kynurenic acid (KynA) and quinolinic acid (QA). We have previously reported an association between the ratio of KynA to QA and hippocampal v...

journal_title：Psychoneuroendocrinology

authors： Savitz J,Dantzer R,Meier TB,Wurfel BE,Victor TA,McIntosh SA,Ford BN,Morris HM,Bodurka J,Teague TK,Drevets WC

更新日期：2015-12-01 00:00:00

abstract：OBJECTIVES:The mechanisms underlying the interaction of psychological stress with the disease course in inflammatory bowel diseases remain unclear. We analyzed the neuroendocrine and cellular immune responses to public speaking stress, and the in vitro adrenergic and glucocorticoid modulation of cytokine production by ...

journal_title：Psychoneuroendocrinology

authors： Langhorst J,Cobelens PM,Kavelaars A,Heijnen CJ,Benson S,Rifaie N,Dobos GJ,Schedlowski M,Elsenbruch S

更新日期：2007-09-01 00:00:00

abstract：:Dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis influences the risk for developing stress-related disorders. Sex-dependent differences in the HPA axis stress response are believed to contribute to the different prevalence rates of stress-related disorders found in men and women. However, studies examini...

journal_title：Psychoneuroendocrinology

authors： Stephens MA,Mahon PB,McCaul ME,Wand GS

更新日期：2016-04-01 00:00:00

abstract：:Psychiatric disorders associated with elevated stress levels, such as depression, are present in many epilepsy patients, including those with mesial Temporal Lobe Epilepsy (mTLE). Evidence suggests that these psychiatric disorders can predate the onset of epilepsy, suggesting a causal/contributory role. Prolonged expo...

journal_title：Psychoneuroendocrinology

authors： Jones NC,Lee HE,Yang M,Rees SM,Morris MJ,O'Brien TJ,Salzberg MR

更新日期：2013-02-01 00:00:00

abstract：:This study investigated the diurnal output of saliva cortisol in women with symptoms of depression postnatally. Twenty-one depressed and 30 non-depressed women at 7.5 weeks postpartum, and 21 non-perinatal controls, collected saliva at waking, 30 min, and 3 and 12h postwaking. Women who were not depressed postnatally ...

journal_title：Psychoneuroendocrinology

authors： Taylor A,Glover V,Marks M,Kammerer M

更新日期：2009-09-01 00:00:00

abstract：:Early adversity (EA) modulates stress hormone secretion in mixed directions. The Accumulation Model suggests that the number of EA predicts patterns of cortisol dysregulations, while the Life Cycle Model of Stress highlights the importance of considering the timing at which EA began, given that brain regions sensitive...

journal_title：Psychoneuroendocrinology

authors： Raymond C,Marin MF,Wolosianski V,Journault AA,Longpré C,Leclaire S,Cernik R,Juster RP,Lupien SJ

更新日期：2020-11-22 00:00:00

abstract：:Determinations of gonadotropins and testosterone were performed in 22 men with hypospadias (H), seven male-to-female transsexuals (T) and in 16 normal men (N), all of similar age. The response of serum FSH and LH to GnRH was determined in six subjects in each group. Oligospermia was found in five of 13 patients with H...

journal_title：Psychoneuroendocrinology

authors： Kula K

更新日期：1986-01-01 00:00:00

abstract：:Salivary cortisol and alpha-amylase are known to have distinctive diurnal profiles. However, little is known about systematic changes in these biomarkers across the adult lifespan. In a study of 185 participants (aged 20-81 years), time-stamped salivary cortisol and alpha-amylase were collected 7 times/day over 10 day...

journal_title：Psychoneuroendocrinology

authors： Nater UM,Hoppmann CA,Scott SB

更新日期：2013-12-01 00:00:00

abstract：:Recent evidence suggests that testosterone is negatively correlated with empathic processes in both men and women. Also, administration of testosterone to young women impairs socio-cognitive performance as assessed using the "Reading the Mind in the Eyes Task", especially among those exposed to elevated testosterone c...

journal_title：Psychoneuroendocrinology

authors： Carré JM,Ortiz TL,Labine B,Moreau BJ,Viding E,Neumann CS,Goldfarb B

更新日期：2015-12-01 00:00:00

abstract：:Previous studies from this laboratory demonstrated that CBA/J mice have impaired striatal dopaminergic supersensitivity in response to subchronic haloperidol administration. Others have speculated that the peripheral hyperprolactinemia produced by haloperidol is necessary for the striatal dopamine receptor supersensit...

journal_title：Psychoneuroendocrinology

authors： Morgan DG,Randall JS,Telford NA,Gordon MN,Sinha YN,Finch CE,Randall PK

更新日期：1987-01-01 00:00:00

abstract：:Studies of the salivary cortisol awakening response (CAR) may be confounded by delays between waking in the morning and obtaining the 'waking' salivary sample. We used wrist actigraphy to provide objective information about waking time, and studied the influence of delays in taking the waking sample on the CAR. Eighty...

journal_title：Psychoneuroendocrinology

authors： Dockray S,Bhattacharyya MR,Molloy GJ,Steptoe A

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Raised maternal anxiety during pregnancy is associated with increased risk of adverse neurodevelopmental outcomes for her child. The mechanisms underlying this are not known but animal studies suggest prenatal stress may alter the function of the placenta. Here we determined whether maternal prenatal anxiety...

journal_title：Psychoneuroendocrinology

authors： O'Donnell KJ,Bugge Jensen A,Freeman L,Khalife N,O'Connor TG,Glover V

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Although the linkage between psychological stress and cortisol is believed to mediate the association of stress with health outcomes, several studies have been unable to demonstrate this association. We suggest this inability may be a consequence of limitations in the measurement approach and/or reliance on ...

journal_title：Psychoneuroendocrinology

authors： Lazarides C,Ward EB,Buss C,Chen WP,Voelkle MC,Gillen DL,Wadhwa PD,Entringer S

更新日期：2020-11-01 00:00:00

abstract：:The current study investigates the effect of a single episode of acute social stress on healthy children's processing of facial expressions of emotion. Healthy nine- and ten-year-old boys (N=39) underwent either a standardized psychosocial laboratory stressor (the Trier Social Stress Test for Children) or a control co...

journal_title：Psychoneuroendocrinology

authors： Chen FS,Schmitz J,Domes G,Tuschen-Caffier B,Heinrichs M

更新日期：2014-02-01 00:00:00

abstract：:The oxytocin receptor (OXTR) is a potential candidate in the pathophysiology of obsessive-compulsive disorder (OCD). The present study investigated the association between common single-nucleotide polymorphism (SNPs) of the OXTR gene and the affected status of OCD or distinct clinical subtypes of OCD including the age...

journal_title：Psychoneuroendocrinology

authors： Kang JI,Kim HW,Kim CH,Hwang EH,Kim SJ

更新日期：2017-12-01 00:00:00

abstract：:Early life events have special importance in the development as postnatal environmental alterations may permanently affect the lifetime vulnerability to diseases. For the interpretation of the long-term consequences it is important to understand the immediate effects. As the role of vasopressin in hypothalamic-pituita...

journal_title：Psychoneuroendocrinology

authors： Zelena D,Stocker B,Barna I,Tóth ZE,Makara GB

更新日期：2015-01-01 00:00:00

abstract：:Among the studies of systemic hormonal and physiological abnormalities associated with anxiety disorders, the most consistent and extensive findings suggest (a) peripheral adrenergic hyperactivity (including increases in norepinephrine but not epinephrine) and functional dysregulation, (b) increased incidence of mitra...

journal_title：Psychoneuroendocrinology

authors： Cameron OG,Nesse RM

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:Subliminal intragastric fatty acid infusion attenuates subjective and brain responses to negative emotion induction. However, the underlying gut-brain signaling mechanisms remain unclear, and it is unknown whether such effect equally applies to positive emotion. OBJECTIVE:We aimed to investigate the interac...

journal_title：Psychoneuroendocrinology

authors： Zhao D,Boey L,Weltens N,Biesiekierski JR,Iven J,Depoortere I,Tack J,Van Oudenhove L

更新日期：2019-10-01 00:00:00