Abstract:
:To evaluate whether the lines occasionally detected on clinical magnetic resonance (MR) images are genuine hippocampal layers, a formalin fixed hippocampal specimen was scanned using T2 weighted sequences at 7 Tesla (voxel dimensions 0.064 x 0.064 x 1 mm) and at 1.5 Tesla (voxel dimensions: 0.156 x 0.156 x 1 mm) and compared with the results of histological examination. In addition, a healthy volunteer was scanned with a T2 weighted sequence at 1.5 Tesla (voxel dimensions: 0.469 x 0.469 x 2 mm). On 7 Tesla images hippocampal layers and the granule cell layer of the dentate were visible. On 1.5 Tesla images of the specimen, the hippocampal layers were again identified, but the granule cell layer of the dentate was not detectable. On 1.5 Tesla images of the hippocampus in vivo, 3 layers could be distinguished in the hippocampus on some slices. These mainly represented the alveus, pyramidal cell layer and stratum radiatum. A dark line consisting of a few pixels possibly represented the dentate gyrus. Our results show that the lines occasionally detected on clinical MR images are likely to be real hippocampal layers. However, the resolution currently used in clinical imaging (typically 0.469 x 0.469 x 2 mm or lower) is not sufficient for the detection of all hippocampal layers. For the reliable detection of all hippocampal layers on MR images an increase by a factor of approximately 20 would be necessary.
journal_name
J Anatjournal_title
Journal of anatomyauthors
Wieshmann UC,Symms MR,Mottershead JP,MacManus DG,Barker GJ,Tofts PS,Revesz T,Stevens JM,Shorvon SDdoi
10.1046/j.1469-7580.1999.19510131.xkeywords:
subject
Has Abstractpub_date
1999-07-01 00:00:00pages
131-5eissn
0021-8782issn
1469-7580journal_volume
195 ( Pt 1)pub_type
杂志文章abstract::Primates have shoulders adapted to a wide range of locomotor functions from terrestrial pronograde quadrupedalism to highly arboreal suspensory behaviours. The shape of the scapula tightly follows these functional differences. Previous analyses of primate postcrania, including the scapula, indicate that quadrupedal mo...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2006.00639.x
更新日期:2006-11-01 00:00:00
abstract::An unbiased stereological counting device (the fractionator) was used to count Purkinje neurons in mammalian cerebella of known weights in order to define the relationship between weight and number. Nucleoli were chosen as the counting unit and numbers were estimated from uniform random samples of wax-embedded tissue ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1993-08-01 00:00:00
abstract::Colloidal carbon was injected intravenously into young rats to label circulating monocytes before making a stab wound in the brain. The rats were killed 3-16 days after the stab wound. Demonstration of non-specific esterase, thiamine pyrophosphatase and 5'-nucleotidase was carried out on the carbon-labelled macrophage...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1987-10-01 00:00:00
abstract::Interference with venous outflow from a limb to stimulate fracture repair and bone growth has a long history, and its beneficial effects have been confirmed by many experimental and clinical studies. With the development of fracture fixation systems, the therapeutic use of circulatory intervention became redundant. Re...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1994-06-01 00:00:00
abstract::The sacroiliac joint (SIJ) is responsible for weight transmission between the spine and lower extremity. However, details of the structure and function of the SIJ remain unclear. In a previous study, we devised a method of quantitatively evaluating the level of degeneration of the SIJ using an age estimation procedure...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12765
更新日期:2018-02-01 00:00:00
abstract::The developing cortical surfaces of long bones are sculpted and modeled by periosteal osteoclasts and osteoblasts. These surfaces also receive the insertions of tendons and ligaments, and these insertion sites too are modeled to form the root systems that anchor them into the cortical bone. The regulatory molecules th...
journal_title:Journal of anatomy
pub_type: 杂志文章
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更新日期:2014-04-01 00:00:00
abstract::Salivary mucins MG1 and MG2 have been found in the oral cavity where they perform several functions such as the formation of the mucous layer covering the oral mucosa and teeth. Recent studies have demonstrated their presence in other organs and tissues. The aim of this study was to determine their expression in human...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2008.01018.x
更新日期:2009-01-01 00:00:00
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journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12924
更新日期:2019-03-01 00:00:00
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journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.2003.00232.x
更新日期:2003-11-01 00:00:00
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journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1976-12-01 00:00:00
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journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1989-02-01 00:00:00
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journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2009.01065.x
更新日期:2009-05-01 00:00:00
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journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1991-12-01 00:00:00
abstract::The olfactory bulb of adult specimens of Carassius auratus was subjected to an autoradiographic study using [3H]thymidine. Adult specimens of Carassius auratus, Barbus meridionalis, Cyprinus carpio and Salmo gairdneri were also studied using light and electron microscopy. Cells were found undergoing mitotic division w...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1989-04-01 00:00:00
abstract::Integrating microdensitometry was used to study changes in the intracellular activity of 4 enzymes during macrophage development. Suspension cultures of blood monocytes from 19 healthy human subjects were examined at 0, 2, 4 and 6 d. Mononuclear phagocytes were harvested by glass adherence and standard methods were us...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1993-08-01 00:00:00
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journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1991-02-01 00:00:00
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journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1983-08-01 00:00:00
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journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2011.01399.x
更新日期:2011-10-01 00:00:00
abstract::Kokartus honorarius from the Middle Jurassic (Bathonian) of Kyrgyzstan is one of the oldest salamanders in the fossil record, characterized by a mixture of plesiomorphic morphological features and characters shared with crown-group salamanders. Here we present a detailed histological analysis of its long bones. The an...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12281
更新日期:2015-04-01 00:00:00
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journal_title:Journal of anatomy
pub_type: 杂志文章,评审
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更新日期:2000-11-01 00:00:00
abstract::The form and position of the developing atrioventricular bundle and its branches has been studied in the hearts of domestic fowl embryos operated upon to induce delayed closure of the interventricular foramen. The operation was performed at 3 days of incubation when the outflow tract of the tubular heart was temporari...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1982-03-01 00:00:00
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journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12466
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journal_title:Journal of anatomy
pub_type: 杂志文章
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更新日期:2016-11-01 00:00:00
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journal_title:Journal of anatomy
pub_type: 杂志文章
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更新日期:2018-02-01 00:00:00
abstract::The distribution and form of amoeboid microglia in the brain of neonatal rats have been studied with the light and electron microscope. With the silver carbonate method of Rio-Hortega, two major 'colonies' of amoeboid microglia are identified: (1) in the supraventricular corpus callosum in which the nerve fibres are w...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1976-02-01 00:00:00
abstract::Classic anatomical methods have failed to determine the precise location, origin and nature of nerve fibres in the inferior hypogastric plexus (IHP). The purpose of this study was to identify the location and nature (adrenergic and/or cholinergic) of IHP nerve fibres and to provide a three-dimensional (3D) representat...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2009.01071.x
更新日期:2009-05-01 00:00:00
abstract::The glycan composition of the N- and O-linked oligosaccharides of the follicle (Sertoli) cells of the urodele amphibian Pleurodeles waltl testis were identified by lectin histochemistry, performed alone or in combination with enzymatic and chemical deglycosylation methods. The follicle cells were shown to contain: (1)...
journal_title:Journal of anatomy
pub_type: 杂志文章
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更新日期:2001-06-01 00:00:00
abstract::Because the cornea is optimized for refraction, it relies on supporting tissues for moistening and nutrition and in particular for immune protection. Its main support tissue is the conjunctiva, in addition to the lacrimal gland, the latter which provides soluble mediators via the tear film. The cornea and conjunctiva ...
journal_title:Journal of anatomy
pub_type: 杂志文章,评审
doi:10.1111/j.1469-7580.2005.00394.x
更新日期:2005-03-01 00:00:00
abstract::This study was done in order to investigate the normal ultrastructure of well-preserved mouse spinal canal ependyma using light, scanning and transmission electron microscopy. The ependymal lining was found to consist of a simple, cuboidal epithelium essentially similar to the unspecialized cuboidal ependyma of the br...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1988-10-01 00:00:00
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journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1995-10-01 00:00:00