Fournier's gangrene in a modern surgical setting: improved survival with aggressive management.

abstract：OBJECTIVE:To assess the utility of percentage free/total prostate-specific antigen (f/tPSA) levels for detecting prostate cancer in a prospectively screened population of men with a 'normal' total PSA level. PATIENTS AND METHODS:Men aged 50-65 years were contacted via their general practitioner and invited for prostat...

journal_title：BJU international

authors： Rowe EW,Laniado ME,Walker MM,Patel A

更新日期：2005-06-01 00:00:00

abstract：OBJECTIVE:To present the renal functional outcomes for patients treated with open partial nephrectomy (OPN) or radiofrequency ablation (RFA) for tumours in a solitary kidney, as renal masses in a solitary kidney present a challenging treatment dilemma. PATIENTS AND METHODS:A retrospective review of institutional datab...

journal_title：BJU international

authors： Raman JD,Raj GV,Lucas SM,Williams SK,Lauer EM,Ahrar K,Matin SF,Leveillee RJ,Cadeddu JA

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVES:To examine the effect of the dual-action 5alpha-reductase inhibitor dutasteride on benign prostatic hyperplasia (BPH)-specific health status, as measured by the BPH Impact Index (BII), and to identify baseline and treatment risk factors for those most bothered by their BPH symptoms at the end of the protocol...

journal_title：BJU international

authors： O'Leary MP,Roehrborn C,Andriole G,Nickel C,Boyle P,Höfner K

更新日期：2003-08-01 00:00:00

abstract：:Accurate prediction is essential for patient counselling, appropriate selection of treatments and determination of eligibility for clinical trials. In this review we assess the available determinants of oncological outcome after radical cystectomy (RC) for transitional cell carcinoma of the urinary bladder. We reviewe...

journal_title：BJU international

authors： Margulis V,Lotan Y,Montorsi F,Shariat SF

更新日期：2008-07-01 00:00:00

abstract：OBJECTIVE:To examine a large, single-surgeon series of patients with prostate cancer who underwent retropubic radical prostatectomy (RRP) for men with postoperative bladder neck contractures (BNCs). PATIENTS AND METHODS:From 1983 to 2007, 4132 men underwent RRP for prostate cancer by one surgeon. All patients had BN r...

journal_title：BJU international

authors： Erickson BA,Meeks JJ,Roehl KA,Gonzalez CM,Catalona WJ

更新日期：2009-12-01 00:00:00

abstract：UNLABELLED:What's known on the subject? and What does the study add? The clinical presentation and complications of lichen sclerosus are well known. What is less well known is the true incidence of the condition. The published figures are all based on attendance at general medical clinics or specialist clinics, but it ...

journal_title：BJU international

authors： Clouston D,Hall A,Lawrentschuk N

更新日期：2011-11-01 00:00:00

abstract：OBJECTIVE:To assess the severity of both stress urinary incontinence (SUI) and overactive bladder (OAB) symptoms during and after the first pregnancy, using a self-reported health-related quality-of-life questionnaire, and to assess the effect of pregnancy and childbirth on bothersome lower urinary tract symptoms (LUTS...

journal_title：BJU international

authors： van Brummen HJ,Bruinse HW,van de Pol G,Heintz AP,van der Vaart CH

更新日期：2006-07-01 00:00:00

abstract：OBJECTIVE:To present our experience of cavernous nerve graft reconstruction, using an autologous nerve vein-guide technique, to restore potency. PATIENTS AND METHODS:Prostate cancers frequently require radical resection involving one or both cavernous nerves that usually results in erectile dysfunction; nerve grafting...

journal_title：BJU international

authors： Fujioka M,Tasaki I,Kitamura R,Yakabe A,Hayashi M,Matsuya F,Miyaguchi T,Tsuruta J

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVE:To assess the impact of positive surgical margins (PSMs) on long-term outcomes after radical prostatectomy (RP), including metastasis, castrate-resistant prostate cancer (CRPC), and prostate cancer-specific mortality (PCSM). PATIENTS AND METHODS:Retrospective study of 4,051 men in the Shared Equal Access Reg...

journal_title：BJU international

authors： Mithal P,Howard LE,Aronson WJ,Terris MK,Cooperberg MR,Kane CJ,Amling C,Freedland SJ

更新日期：2016-02-01 00:00:00

abstract：OBJECTIVE:To determine the effects of cycling oestrogen in rabbits, as oestrogen is essential for physiological maintenance and integrity of the female urogenital tract. MATERIALS AND METHODS:Changes in circulating oestrogen have marked effects on the bladder of experimental animals, with ovariectomy (Ovx) inducing sm...

journal_title：BJU international

authors： Palmieri K,Mannikarottu AS,Chichester P,Kogan B,Leggett RE,Whitbeck C,Levin RM

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVE:To assess the risk factors for haemorrhage and renal fracture associated with renal cryoablation. MATERIALS AND METHODS:In a porcine model, 120 cryoablations were administered in 26 pigs, with five groups of 24 ice-balls each; in groups 1 and 2 asynchronous cryoprobe activation was evaluated for the 1.47- an...

journal_title：BJU international

authors： Hruby G,Edelstein A,Karpf J,Durak E,Phillips C,Lehman D,Landman J

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVES:To report the 2-year clinical and biochemical follow-up of symptomatic men who had a high prostate-specific-antigen (PSA) level, for whom our policy has been to avoid biopsy in those with a normal repeat PSA, as minimizing negative prostate biopsies is an important goal in managing men with a high PSA, where...

journal_title：BJU international

authors： Singh R,Cahill D,Popert R,O'Brien TS

更新日期：2003-12-01 00:00:00

abstract：OBJECTIVE:To describe a modification of the posterior prone retroperitoneoscopic nephrectomy, which allows the entire operation to be performed through a single instrument port. PATIENTS AND METHODS:With the patient prone, a retroperitoneal working space is created using a custom-made balloon lateral to the sacrospina...

journal_title：BJU international

authors： Msezane LP,Mushtaq I,Gundeti MS

更新日期：2009-05-01 00:00:00

abstract：OBJECTIVE:To report the long-term results with the Mainz Pouch II procedure. PATIENTS AND METHODS:Between 1990 and 2000 a Mainz Pouch II ureterosigmoidostomy was used in 123 patients (49 females and 74 males, mean age 43.6 years, range: 1-73). The indications for urinary diversion were cystectomy for bladder cancer in...

journal_title：BJU international

authors： D'elia G,Pahernik S,Fisch M,Hohenfellner R,Thüroff JW

更新日期：2004-05-01 00:00:00

abstract：OBJECTIVE:To simplify the original Preoperative Aspects and Dimensions Used for an Anatomical (PADUA) classification of renal tumours, generating a new system able to predict equally or better the risk of overall complications in patients undergoing partial nephrectomy (PN); and to test if the addition of the contact s...

journal_title：BJU international

authors： Ficarra V,Porpiglia F,Crestani A,Minervini A,Antonelli A,Longo N,Novara G,Giannarini G,Fiori C,Simeone C,Carini M,Mirone V

更新日期：2019-04-09 00:00:00

abstract：OBJECTIVES:To present long-term oncological outcomes of patients with paratesticular sarcoma treated by a multidisciplinary team. PATIENTS AND METHODS:Patients managed at the Princess Margaret Cancer Centre, between 1990 and 2012, were analysed. A sarcoma expert performed central pathology review. Kaplan-Meier graphs ...

journal_title：BJU international

authors： Goldberg H,Wong LM,Dickson B,Catton C,Yap SA,Alkasab T,Evans A,van der Kwast T,Jewett MAS,Hamilton RJ

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVES:To provide data on the prevalence of urinary, bowel and sexual dysfunction in Northern Ireland (NI), to act as a baseline for studies of prostate cancer outcomes and to aid service provision within the general population. SUBJECTS AND METHODS:A cross-sectional postal survey of 10 000 men aged ≥40 years in N...

journal_title：BJU international

authors： Donnelly DW,Donnelly C,Kearney T,Weller D,Sharp L,Downing A,Wilding S,Wright P,Kind P,Catto JWF,Cross WR,Mason MD,McCaughan E,Wagland R,Watson E,Mottram R,Allen M,Butcher H,Hounsome L,Selby P,Huws D,Brewster DH

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVE:To determine the role of hypoxia-inducible factor-2alpha (HIF2alpha) on the sensitivity of renal cell carcinoma (RCC) cell lines to ionizing radiation and to determine if the mTOR antagonist, rapamycin, could decrease HIF2alpha protein levels. MATERIALS AND METHODS:Cell lines expressing stable short-hairpin ...

journal_title：BJU international

authors： Bhatt RS,Landis DM,Zimmer M,Torregrossa J,Chen S,Sukhatme VP,Iliopoulos O,Balk S,Bubley GJ

更新日期：2008-08-01 00:00:00

abstract：OBJECTIVE:To investigate the potential role of platelet-derived growth factor-AA (PDGF-AA) and the PDGF-α receptor as prognostic markers in Wilms' tumour. PATIENTS AND METHODS:The expression of PDGF-AA and PDGF-α were investigated using immunohistochemical analysis of 62 Wilms' tumours. Patients were treated with chem...

journal_title：BJU international

authors： Ghanem M,Nijman R,Safan M,van der Kwast T,Vansteenbrugge G

更新日期：2010-11-01 00:00:00

abstract：OBJECTIVE:To review our experience in the management of secondary pelvi-ureteric junction obstruction (PUJO) comparing endopyelotomy with pyeloplasty. PATIENTS AND METHODS:We retrospectively analysed our database of 58 patients having undergone operative management of PUJO after failed primary management, including 41...

journal_title：BJU international

authors： Vannahme M,Mathur S,Davenport K,Timoney AG,Keeley FX Jr

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To investigate the potential utility of a new combined immunostaining technique for diagnosing prostate cancer from histological analysis of needle biopsy specimens. MATERIALS AND METHODS:Tissue was immunostained with a combination of antibodies against a basal cell marker (p63), and an enzyme commonly overe...

journal_title：BJU international

authors： Molinié V,Hervé JM,Lugagne PM,Lebret T,Botto H

更新日期：2006-05-01 00:00:00

abstract：UNLABELLED:WHAT'S KNOWN ON THE SUBJECT? AND WHAT DOES THE STUDY ADD?: Systems for image guidance during laparoscopic surgery can be broadly defined as systems that enable the surgeon to refer to preoperatively gathered information during the procedure. For a laparoscopic system the preoperative information can be overl...

journal_title：BJU international

authors： Thompson S,Penney G,Billia M,Challacombe B,Hawkes D,Dasgupta P

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVES:To use the Fragility Index to evaluate the robustness of statistically significant findings from urological randomised controlled trials (RCTs). MATERIALS AND METHODS:The 'Fragility Index' is defined as the minimum number of patients in one arm of a trial whose status would have to change from 'event' to 'n...

journal_title：BJU international

authors： Narayan VM,Gandhi S,Chrouser K,Evaniew N,Dahm P

更新日期：2018-07-01 00:00:00

abstract：OBJECTIVE:To evaluate the diffusion of nephron-sparing modalities (NSM) for the treatment of renal neoplasms in the USA over the last decade and to identify the factors associated with renal procedure selection. PATIENTS AND METHODS:The Nationwide Inpatient Sample was utlized to identify patients undergoing cryo/radio...

journal_title：BJU international

authors： Woldrich JM,Palazzi K,Stroup SP,Sur RL,Parsons JK,Chang D,Derweesh IH

更新日期：2013-06-01 00:00:00

abstract：:• Mid-urethral synthetic slings (MUSS) have grown in acceptance and popularity to gain a foremost position in stress urinary incontinence (SUI) surgery. • There are numerous studies that provide a large amount of Level 1 and 2 evidence that support the concept of a sling placed at the level of the mid-urethra. • Long-...

journal_title：BJU international

authors： Fong ED,Nitti VW

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVE:To assess the safety and efficacy of the tension-free vaginal tape procedure in the treatment of primary genuine stress incontinence. PATIENTS AND METHODS:A two-centre follow-up study was conducted on 40 women with urodynamically confirmed primary genuine stress incontinence who had a tension-free vaginal ta...

journal_title：BJU international

authors： Moran PA,Ward KL,Johnson D,Smirni WE,Hilton P,Bibby J

更新日期：2000-07-01 00:00:00

abstract：OBJECTIVE:To investigate the possibility of using urodynamic variables to predict upper urinary tract dilatation (UUTD) in children with neurogenic bladder-sphincter dysfunction (NBSD). PATIENTS AND METHODS:The study included 200 children with NBSD, of whom 103 had UUTD and 97 did not; they were examined using routine...

journal_title：BJU international

authors： Wang QW,Wen JG,Song DK,Su J,Che YY,Zhang P,Du AM,Wang DX,Zhu QH,Wei JX

更新日期：2006-12-01 00:00:00

abstract：OBJECTIVE:To aid the interpretation of the trends in prostate cancer mortality, which declined in the UK in the early 1990 s for unknown reasons, by investigating prostate cancer death rates, incidence and treatments in England and Wales in 1975-2004. METHODS:Join-point regression was used to assess secular trends in ...

journal_title：BJU international

authors： Hussain S,Gunnell D,Donovan J,McPhail S,Hamdy F,Neal D,Albertsen P,Verne J,Stephens P,Trotter C,Martin RM

更新日期：2008-03-01 00:00:00

abstract：:Novel oral anti-coagulants (NOACs) are increasingly being used in clinical practice and are set to almost entirely replace the vitamin K antagonists, such as warfarin, in the near future. Similarly, new antiplatelet agents are now regularly used in place of older agents, such as aspirin and clopidogrel. In an ageing p...

journal_title：BJU international

authors： Ellis G,John Camm A,Datta SN

更新日期：2015-11-01 00:00:00

abstract：OBJECTIVES:ERG-gene rearrangement defines a distinct molecular subtype of PCA with potential biological and clinical implications. To identify a molecular signature reflective of the downstream effects of ERG-mediated transcriptional regulation with prognostic implication in patients with prostate cancer (PCA). MATERI...

journal_title：BJU international

authors： Bismar TA,Alshalalfa M,Petersen LF,Teng LH,Gerke T,Bakkar A,Al-Mami A,Liu S,Dolph M,Mucci LA,Alhajj R

更新日期：2014-02-01 00:00:00