ovo/svb integrates Wingless and DER pathways to control epidermis differentiation.

abstract：:Clathrin is the structural protein of coated membranes involved in receptor-mediated endocytosis and aspects of Golgi sorting in eukaryotic cells. We have now detected a stoichiometric complex of clathrin with a novel protein of M(r) approximately 100,000 (100K) in lysates of different mammalian cells. Formation of th...

journal_title：Nature

authors： Pleasure IT,Black MM,Keen JH

更新日期：1993-09-30 00:00:00

abstract：:Nearly all protocols requiring shared quantum information--such as quantum teleportation or key distribution--rely on entanglement between distant parties. However, entanglement is difficult to characterize experimentally. All existing techniques for doing so, including entanglement witnesses or Bell inequalities, dis...

journal_title：Nature

authors： Walborn SP,Souto Ribeiro PH,Davidovich L,Mintert F,Buchleitner A

更新日期：2006-04-20 00:00:00

abstract：:The crown-of-thorns starfish (COTS, the Acanthaster planci species group) is a highly fecund predator of reef-building corals throughout the Indo-Pacific region. COTS population outbreaks cause substantial loss of coral cover, diminishing the integrity and resilience of reef ecosystems. Here we sequenced genomes of CO...

journal_title：Nature

authors： Hall MR,Kocot KM,Baughman KW,Fernandez-Valverde SL,Gauthier MEA,Hatleberg WL,Krishnan A,McDougall C,Motti CA,Shoguchi E,Wang T,Xiang X,Zhao M,Bose U,Shinzato C,Hisata K,Fujie M,Kanda M,Cummins SF,Satoh N,Degnan SM

更新日期：2017-04-05 00:00:00

abstract：:Many collective human activities, including violence, have been shown to exhibit universal patterns. The size distributions of casualties both in whole wars from 1816 to 1980 and terrorist attacks have separately been shown to follow approximate power-law distributions. However, the possibility of universal patterns r...

journal_title：Nature

authors： Bohorquez JC,Gourley S,Dixon AR,Spagat M,Johnson NF

更新日期：2009-12-17 00:00:00

abstract：:Spinal cord injury disrupts the communication between the brain and the spinal circuits that orchestrate movement. To bypass the lesion, brain-computer interfaces have directly linked cortical activity to electrical stimulation of muscles, and have thus restored grasping abilities after hand paralysis. Theoretically, ...

journal_title：Nature

authors： Capogrosso M,Milekovic T,Borton D,Wagner F,Moraud EM,Mignardot JB,Buse N,Gandar J,Barraud Q,Xing D,Rey E,Duis S,Jianzhong Y,Ko WK,Li Q,Detemple P,Denison T,Micera S,Bezard E,Bloch J,Courtine G

更新日期：2016-11-10 00:00:00

abstract：:Neurons in the visual cortex are selectively responsive to light or dark bars presented at particular orientations. On the basis of physiological data, this orientation selectivity is hypothesized as being due at least partially to intracortical inhibitory mechanisms. But this hypothesis has been challenged by intrace...

journal_title：Nature

authors： Hata Y,Tsumoto T,Sato H,Hagihara K,Tamura H

更新日期：1988-10-27 00:00:00

abstract：:Small synthetic molecules called growth-hormone secretagogues (GHSs) stimulate the release of growth hormone (GH) from the pituitary. They act through GHS-R, a G-protein-coupled receptor for which the ligand is unknown. Recent cloning of GHS-R strongly suggests that an endogenous ligand for the receptor does exist and...

journal_title：Nature

authors： Kojima M,Hosoda H,Date Y,Nakazato M,Matsuo H,Kangawa K

更新日期：1999-12-09 00:00:00

abstract：:Regular mesoporous oxide materials have been widely studied and have a range of potential applications, such as catalysis, absorption and separation. They are not generally considered for their optical and electronic properties. Elemental semiconductors with nanopores running through them represent a different form of...

journal_title：Nature

authors： Armatas GS,Kanatzidis MG

更新日期：2006-06-29 00:00:00

abstract：:The spontaneously hypertensive rat and the stroke-prone spontaneously hypertensive rat are useful models for human hypertension. In these strains hypertension is a polygenic trait, in which both autosomal and sex-linked genes can influence blood pressure. Linkage studies in crosses between the stroke-prone spontaneous...

journal_title：Nature

authors： Hilbert P,Lindpaintner K,Beckmann JS,Serikawa T,Soubrier F,Dubay C,Cartwright P,De Gouyon B,Julier C,Takahasi S

更新日期：1991-10-10 00:00:00

abstract：:Major histocompatibility complex (MHC) class II molecules are highly polymorphic cell-surface glycoproteins that present antigenic peptides to CD4+ T lymphocytes. The normal assembly of class II molecules with cognate peptides for antigen presentation requires an accessory function provided by a gene mapping to the cl...

journal_title：Nature

authors： Fling SP,Arp B,Pious D

更新日期：1994-04-07 00:00:00

abstract：:Lake Victoria, together with its satellite lakes, harbours roughly 200 endemic forms of cichlid fishes that are classified as 'haplochromines' and yet the lake system is less than a million years old. This 'flock' has attracted attention because of the possibility that it evolved within the lake from one ancestral spe...

journal_title：Nature

authors： Meyer A,Kocher TD,Basasibwaki P,Wilson AC

更新日期：1990-10-11 00:00:00

abstract：:The question of whether DNA is able to transport electrons has attracted much interest, particularly as this ability may play a role as a repair mechanism after radiation damage to the DNA helix. Experiments addressing DNA conductivity have involved a large number of DNA strands doped with intercalated donor and accep...

journal_title：Nature

authors： Fink HW,Schönenberger C

更新日期：1999-04-01 00:00:00

abstract：:Transport vesicles derived from the Golgi apparatus are thought to mediate biosynthetic transport across the Golgi stack. These vesicles are surrounded by a protein coat whose principal constituents are coatomer (a complex of seven distinct subunits or COPs) and ADP-ribosylation factor (ARF, an N-myristylated small GT...

journal_title：Nature

authors： Orcl L,Palmer DJ,Amherdt M,Rothman JE

更新日期：1993-08-19 00:00:00

abstract：:The two-dimensional electron system is a powerful laboratory for investigating the physics of interacting particles. Application of a large magnetic field produces massively degenerate quantum levels known as Landau levels; within a Landau level the kinetic energy of the electrons is suppressed, and electron-electron ...

journal_title：Nature

authors： Dial OE,Ashoori RC,Pfeiffer LN,West KW

更新日期：2010-03-25 00:00:00

abstract：:Schistosoma japonicum is a parasitic flatworm that causes human schistosomiasis, which is a significant cause of morbidity in China and the Philippines. Here we present a draft genomic sequence for the worm. The genome provides a global insight into the molecular architecture and host interaction of this complex metaz...

journal_title：Nature

authors： Schistosoma japonicum Genome Sequencing and Functional Analysis Consortium.

更新日期：2009-07-16 00:00:00

abstract：:In the few species of birds in which males form display partnerships to attract females, one male secures most or all of the copulations. This leads to the question of why subordinate males help in the absence of observable reproductive benefits. Hamilton's concept of kin selection, whereby individuals can benefit ind...

journal_title：Nature

authors： Krakauer AH

更新日期：2005-03-03 00:00:00

abstract：:Angiogenesis, the formation of new capillaries from pre-existing vessels, is essential for tumour progression. Angiostatin, a proteolytic fragment of plasminogen that was first isolated from the serum and urine of tumour-bearing mice, inhibits angiogenesis and thereby growth of primary and metastatic tumours. Radiothe...

journal_title：Nature

authors： Mauceri HJ,Hanna NN,Beckett MA,Gorski DH,Staba MJ,Stellato KA,Bigelow K,Heimann R,Gately S,Dhanabal M,Soff GA,Sukhatme VP,Kufe DW,Weichselbaum RR

更新日期：1998-07-16 00:00:00

abstract：:High-pressure transitions are thought to modify hydrogen molecules to a molecular metallic solid and finally to an atomic metal1, which is predicted to have exotic physical properties and the topology of a two-component (electron and proton) superconducting superfluid condensate2,3. Therefore, understanding such trans...

journal_title：Nature

authors： Ji C,Li B,Liu W,Smith JS,Majumdar A,Luo W,Ahuja R,Shu J,Wang J,Sinogeikin S,Meng Y,Prakapenka VB,Greenberg E,Xu R,Huang X,Yang W,Shen G,Mao WL,Mao HK

更新日期：2019-09-01 00:00:00

abstract：:Conrad et al. have generated human adult germline stem cells (haGSCs) from human testicular tissue, which they claim have similar pluripotent properties to human embryonic stem cells (hESCs). Here we investigate the pluripotency of haGSCs by using global gene-expression analysis based on their gene array data and comp...

journal_title：Nature

authors： Ko K,Araúzo-Bravo MJ,Tapia N,Kim J,Lin Q,Bernemann C,Han DW,Gentile L,Reinhardt P,Greber B,Schneider RK,Kliesch S,Zenke M,Schöler HR

更新日期：2010-06-24 00:00:00

abstract：:Aberrant regulation of RNA stability has an important role in many disease states. Deregulated post-transcriptional modulation, such as that governed by microRNAs targeting linear sequence elements in messenger RNAs, has been implicated in the progression of many cancer types. A defining feature of RNA is its ability ...

journal_title：Nature

authors： Goodarzi H,Zhang S,Buss CG,Fish L,Tavazoie S,Tavazoie SF

更新日期：2014-09-11 00:00:00

abstract：:Achieving site selectivity in carbon-hydrogen (C-H) functionalization reactions is a long-standing challenge in organic chemistry. The small differences in intrinsic reactivity of C-H bonds in any given organic molecule can lead to the activation of undesired C-H bonds by a non-selective catalyst. One solution to this...

journal_title：Nature

authors： Tang RY,Li G,Yu JQ

更新日期：2014-03-13 00:00:00

abstract：:The realization of superfluidity in a dilute gas of fermionic atoms, analogous to superconductivity in metals, represents a long-standing goal of ultracold gas research. In such a fermionic superfluid, it should be possible to adjust the interaction strength and tune the system continuously between two limits: a Barde...

journal_title：Nature

authors： Greiner M,Regal CA,Jin DS

更新日期：2003-12-04 00:00:00

abstract：:Change history: In Fig. 1b and c of this Letter, the inset times in the DIC and GFP microscopy images should be in minutes ('min') instead of seconds ('s'). This has not been corrected online. ...

journal_title：Nature

authors： Stewart MP,Helenius J,Toyoda Y,Ramanathan SP,Muller DJ,Hyman AA

更新日期：2019-07-01 00:00:00

abstract：:Immune recognition of protein antigens relies on the combined interaction of multiple antibody loops, which provide a fairly large footprint and constrain the size and shape of protein surfaces that can be targeted. Single protein loops can mediate extremely high-affinity binding, but it is unclear whether such a mech...

journal_title：Nature

authors： Ekiert DC,Kashyap AK,Steel J,Rubrum A,Bhabha G,Khayat R,Lee JH,Dillon MA,O'Neil RE,Faynboym AM,Horowitz M,Horowitz L,Ward AB,Palese P,Webby R,Lerner RA,Bhatt RR,Wilson IA

更新日期：2012-09-27 00:00:00

abstract：:Long before infants reach, crawl or walk, they explore the world by looking: they look to learn and to engage, giving preferential attention to social stimuli, including faces, face-like stimuli and biological motion. This capacity-social visual engagement-shapes typical infant development from birth and is pathognomo...

journal_title：Nature

authors： Constantino JN,Kennon-McGill S,Weichselbaum C,Marrus N,Haider A,Glowinski AL,Gillespie S,Klaiman C,Klin A,Jones W

更新日期：2017-07-20 00:00:00

abstract：:Tumour necrosis factor is a trimeric molecule, each subunit of which consists of an antiparallel beta-sandwich. Individual subunits from the trimer by a novel edge-to-face packing of beta-sheets. A comparison of the subunit fold with that of other proteins reveals a remarkable similarity to the 'jelly-roll' structural...

journal_title：Nature

authors： Jones EY,Stuart DI,Walker NP

更新日期：1989-03-16 00:00:00

abstract：: ...

journal_title：Nature

authors：

更新日期：2018-12-01 00:00:00

abstract：:Quantum computers are expected to outperform conventional computers in several important applications, from molecular simulation to search algorithms, once they can be scaled up to large numbers-typically millions-of quantum bits (qubits)1-3. For most solid-state qubit technologies-for example, those using superconduc...

journal_title：Nature

authors： Yang CH,Leon RCC,Hwang JCC,Saraiva A,Tanttu T,Huang W,Camirand Lemyre J,Chan KW,Tan KY,Hudson FE,Itoh KM,Morello A,Pioro-Ladrière M,Laucht A,Dzurak AS

更新日期：2020-04-01 00:00:00

abstract：:Replication of multipotential stem cells in long-term murine bone marrow cell culture is known to depend on the development of an adherent stromal cell layer. In these conditions, restricted haematopoietic progenitor cells have also been generated for up to several months1-3. However, maturation is observed only in th...

journal_title：Nature

authors： Wendling F,Shreeve MM,McLeod DL,Axelrad AA

更新日期：1983-10-13 00:00:00

abstract：:Metastasis is the main cause of death in people with cancer. To colonize distant organs, circulating tumour cells must overcome many obstacles through mechanisms that we are only now starting to understand. These include infiltrating distant tissue, evading immune defences, adapting to supportive niches, surviving as ...

journal_title：Nature

authors： Massagué J,Obenauf AC

更新日期：2016-01-21 00:00:00