Implementation of on-site screening sigmoidoscopy positively influences utilization by primary care providers.

Abstract:

BACKGROUND & AIMS:Sigmoidoscopy is an effective screening strategy for colorectal cancer that is not widely used by primary care providers. The aim of this study was to assess the impact of "academic detailing" in the form of an outreach educational seminar combined with implementation of on-site sigmoidoscopy services performed by university-based gastroenterologists on provider compliance. METHODS:A controlled trial was initiated at 9 urban neighborhood health centers, including 4 intervention and 5 comparison sites. Baseline data on provider attitudes and practice patterns were collected using a validated questionnaire. Outcome measures included a year 1 follow-up survey of provider attitudes and quarterly review of screening sigmoidoscopy referrals using appointment logs to assess utilization. RESULTS:Overall self-reported compliance rates for screening sigmoidoscopy increased by 36% (baseline, 24%; year 1, 60%) for the intervention group vs. only 7% (baseline, 19%; year 1, 26%) for the comparison group (P = 0. 001). When stratified by site, compliance rates increased at each intervention site (range, 7%-92%) but at only 2 control sites. Use of screening sigmoidoscopy was also significantly greater at the intervention sites (47% vs. 4%; P

journal_name

Gastroenterology

journal_title

Gastroenterology

authors

Schroy PC,Heeren T,Bliss CM,Pincus J,Wilson S,Prout M

doi

10.1053/gast.1999.0029900304

keywords:

subject

Has Abstract

pub_date

1999-08-01 00:00:00

pages

304-11

issue

2

eissn

0016-5085

issn

1528-0012

pii

S0016508599001407

journal_volume

117

pub_type

临床试验,杂志文章
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    doi:10.1016/0016-5085(92)90091-c

    authors: Crowe R,Kamm MA,Burnstock G,Lennard-Jones JE

    更新日期:1992-02-01 00:00:00

  • Folic acid transport in organ-cultured mucosa of human intestine. Evidence for distinct carriers.

    abstract::The transport of folic acid was investigated in organ-cultured endoscopic biopsy specimens of intestinal mucosa from normal subjects. In the proximal small intestine at pH 5.5 and 6.5, [3H]folic acid accumulated to concentrations 2.64- and 2.17-fold higher than those of the medium, respectively, but at pH 7.5 the conc...

    journal_title:Gastroenterology

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    doi:10.1016/0016-5085(90)90614-7

    authors: Zimmerman J

    更新日期:1990-10-01 00:00:00

  • Autologous hematopoietic stem cell transplantation in patients with refractory Crohn's disease.

    abstract:BACKGROUND & AIMS:Crohn's disease (CD) is an immunologically mediated inflammatory disease of the gastrointestinal tract. Due to a high morbidity and/or an increase in mortality in refractory cases, a new treatment approach is needed. In theory, maximum immune ablation by autologous hematopoietic stem cell transplantat...

    journal_title:Gastroenterology

    pub_type: 临床试验,杂志文章

    doi:10.1053/j.gastro.2004.11.051

    authors: Oyama Y,Craig RM,Traynor AE,Quigley K,Statkute L,Halverson A,Brush M,Verda L,Kowalska B,Krosnjar N,Kletzel M,Whitington PF,Burt RK

    更新日期:2005-03-01 00:00:00

  • HCCR-1-interacting molecule "deleted in polyposis 1" plays a tumor-suppressor role in colon carcinogenesis.

    abstract:BACKGROUND & AIMS:Human cervical cancer oncogene (HCCR-1) has appeared to act as a negative regulator of p53 and contributes to tumorigenesis of various organs including the colon. We identified the HCCR-1 binding protein deleted in polyposis 1 (DP1) and accessed the role of HCCR-1 and DP1 in colon tumorigenesis. METH...

    journal_title:Gastroenterology

    pub_type: 杂志文章

    doi:10.1053/j.gastro.2006.03.055

    authors: Shin SM,Chung YJ,Oh ST,Jeon HM,Hwang LJ,Namkoong H,Kim HK,Cho GW,Hur SY,Kim TE,Lee YS,Park YG,Ko J,Kim JW

    更新日期:2006-06-01 00:00:00

  • Tuft Cells Inhibit Pancreatic Tumorigenesis in Mice by Producing Prostaglandin D2.

    abstract:BACKGROUND & AIMS:Development of pancreatic ductal adenocarcinoma (PDA) involves acinar to ductal metaplasia and genesis of tuft cells. It has been a challenge to study these rare cells because of the lack of animal models. We investigated the role of tuft cells in pancreatic tumorigenesis. METHODS:We performed studie...

    journal_title:Gastroenterology

    pub_type: 杂志文章

    doi:10.1053/j.gastro.2020.07.037

    authors: DelGiorno KE,Chung CY,Vavinskaya V,Maurer HC,Novak SW,Lytle NK,Ma Z,Giraddi RR,Wang D,Fang L,Naeem RF,Andrade LR,Ali WH,Tseng H,Tsui C,Gubbala VB,Ridinger-Saison M,Ohmoto M,Erikson GA,O'Connor C,Shokhirev MN,Hah

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  • Efficient detection of hereditary nonpolyposis colorectal cancer gene carriers by screening for tumor microsatellite instability before germline genetic testing.

    abstract:BACKGROUND & AIMS:The optimal strategy for the detection of hereditary nonpolyposis colorectal cancer (HNPCC) gene carriers remains uncertain. We evaluated whether microsatellite instability (MSI) analysis or MSH2 and MLH1 protein immunostaining of tumors will screen individuals efficiently for germline MSH2 and MLH1 t...

    journal_title:Gastroenterology

    pub_type: 杂志文章

    doi:10.1053/gast.2001.20874

    authors: Terdiman JP,Gum JR Jr,Conrad PG,Miller GA,Weinberg V,Crawley SC,Levin TR,Reeves C,Schmitt A,Hepburn M,Sleisenger MH,Kim YS

    更新日期:2001-01-01 00:00:00

  • The many faces of celiac disease: clinical presentation of celiac disease in the adult population.

    abstract::The major modes of presentation of patients with celiac disease are the classic diarrhea-predominant form and silent celiac disease. Those with silent celiac disease lack diarrhea, although they may present with manifestations of celiac disease that include an irritable bowel syndrome, anemia, osteoporosis, neurologic...

    journal_title:Gastroenterology

    pub_type: 杂志文章

    doi:10.1053/j.gastro.2005.02.016

    authors: Green PH

    更新日期:2005-04-01 00:00:00

  • The Apc 1322T mouse develops severe polyposis associated with submaximal nuclear beta-catenin expression.

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    journal_title:Gastroenterology

    pub_type: 杂志文章

    doi:10.1053/j.gastro.2009.02.058

    authors: Pollard P,Deheragoda M,Segditsas S,Lewis A,Rowan A,Howarth K,Willis L,Nye E,McCart A,Mandir N,Silver A,Goodlad R,Stamp G,Cockman M,East P,Spencer-Dene B,Poulsom R,Wright N,Tomlinson I

    更新日期:2009-06-01 00:00:00

  • A circulating ligand for galectin-3 is a haptoglobin-related glycoprotein elevated in individuals with colon cancer.

    abstract:BACKGROUND & AIMS:Galectin-3 is a beta-galactoside-binding protein implicated in tumor progression and metastasis of colorectal cancers. To determine whether circulating galectin-3 ligands are related to the presence of colon cancer, we sought to identify and quantify ligands in serum that bind to galectin-3. METHODS:...

    journal_title:Gastroenterology

    pub_type: 杂志文章

    doi:10.1053/j.gastro.2004.06.016

    authors: Bresalier RS,Byrd JC,Tessler D,Lebel J,Koomen J,Hawke D,Half E,Liu KF,Mazurek N,Great Lakes-New England Clinical and Epidemiology Center of the Early Detection Research Network.

    更新日期:2004-09-01 00:00:00

  • Risk of colorectal cancer in patients prescribed statins, nonsteroidal anti-inflammatory drugs, and cyclooxygenase-2 inhibitors: nested case-control study.

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    journal_title:Gastroenterology

    pub_type: 杂志文章,多中心研究

    doi:10.1053/j.gastro.2007.05.023

    authors: Vinogradova Y,Hippisley-Cox J,Coupland C,Logan RF

    更新日期:2007-08-01 00:00:00

  • The pregnane X receptor locus is associated with susceptibility to inflammatory bowel disease.

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    journal_title:Gastroenterology

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    更新日期:2006-02-01 00:00:00

  • Butyrate, mesalamine, and factor XIII in experimental colitis in the rat: effects on transglutaminase activity.

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    pub_type: 杂志文章

    doi:10.1016/0016-5085(94)90598-3

    authors: D'Argenio G,Cosenza V,Sorrentini I,De Ritis F,Gatto A,Delle Cave M,D'Armiento FP,Mazzacca G

    更新日期:1994-02-01 00:00:00

  • Growth rate of asymptomatic hepatocellular carcinoma and its clinical implications.

    abstract::The growth rate of 31 asymptomatic hepatocellular carcinomas (diameter less than or equal to 5 cm) discovered in 28 patients by a prospective screening program was determined by real-time ultrasonography over 36-860 days. Except for one tumor that shrank on follow-up, the doubling time ranged from 29 to 398 days, with...

    journal_title:Gastroenterology

    pub_type: 杂志文章

    doi:10.1016/0016-5085(85)90324-5

    authors: Sheu JC,Sung JL,Chen DS,Yang PM,Lai MY,Lee CS,Hsu HC,Chuang CN,Yang PC,Wang TH

    更新日期:1985-08-01 00:00:00

  • Somatosensory evoked potentials in hepatic encephalopathy.

    abstract::Median nerve somatosensory evoked potentials were recorded from 33 patients with various degrees of hepatic failure and from 10 age-matched controls. Within 20 ms poststimulation, one negative peak (N13) could be recorded from the middle of the back of the patient's neck at the C2 vertebral level. Within 150 ms, three...

    journal_title:Gastroenterology

    pub_type: 杂志文章

    doi:10.1016/0016-5085(85)90460-3

    authors: Yang SS,Chu NS,Liaw YF

    更新日期:1985-09-01 00:00:00

  • Control of ascites absorption in anesthetized cats: effects of intraperitoneal pressure, protein, and furosemide diuresis.

    abstract::There is considerable evidence that fluids are removed from the peritoneal cavity by drainage into lymphatics lining the surface of the diaphragm, but there is little quantitative information on the rate of reabsorption as affected by conditions which exist in cirrhotic ascites. In the present study a plethysmographic...

    journal_title:Gastroenterology

    pub_type: 杂志文章

    doi:

    authors: Zink J,Greenway CV

    更新日期:1977-11-01 00:00:00

  • Bile and stone analysis in two infants with brown pigment gallstones and infected bile.

    abstract::Two infants under 3 mo of age who presented with obstructive jaundice secondary to cholelithiasis are reported. Neither infant had any congenital anatomic abnormality of the biliary tract leading to stasis, yet both had cultures of gallbladder bile that grew abundant bacteria. In both, recovery of gallbladder bile and...

    journal_title:Gastroenterology

    pub_type: 杂志文章

    doi:10.1016/s0016-5085(89)91579-5

    authors: Treem WR,Malet PF,Gourley GR,Hyams JS

    更新日期:1989-02-01 00:00:00

  • Identification of risk loci for Crohn's disease phenotypes using a genome-wide association study.

    abstract:BACKGROUND & AIMS:Crohn's disease is a highly heterogeneous inflammatory bowel disease comprising multiple clinical phenotypes. Genome-wide association studies (GWASs) have associated a large number of loci with disease risk but have not associated any specific genetic variants with clinical phenotypes. We performed a ...

    journal_title:Gastroenterology

    pub_type: 杂志文章

    doi:10.1053/j.gastro.2014.12.030

    authors: Alonso A,Domènech E,Julià A,Panés J,García-Sánchez V,Mateu PN,Gutiérrez A,Gomollón F,Mendoza JL,Garcia-Planella E,Barreiro-de Acosta M,Muñoz F,Vera M,Saro C,Esteve M,Andreu M,Chaparro M,Manyé J,Cabré E,López-Lasanta

    更新日期:2015-04-01 00:00:00

  • Prospective study of dietary fiber, whole grain foods, and small intestinal cancer.

    abstract:BACKGROUND & AIMS:Although a number of epidemiologic studies have found dietary fiber and whole grains to be inversely associated with colorectal cancer incidence, studies of dietary and other risk factors for small intestinal cancer have been sparse and all of a case-control design. We conducted a prospective cohort s...

    journal_title:Gastroenterology

    pub_type: 杂志文章

    doi:10.1053/j.gastro.2008.07.015

    authors: Schatzkin A,Park Y,Leitzmann MF,Hollenbeck AR,Cross AJ

    更新日期:2008-10-01 00:00:00

  • Super-Enhancer-Driven Long Non-Coding RNA LINC01503, Regulated by TP63, Is Over-Expressed and Oncogenic in Squamous Cell Carcinoma.

    abstract:BACKGROUND & AIMS:Long non-coding RNAs (lncRNAs) are expressed in tissue-specific pattern, but it is not clear how these are regulated. We aimed to identify squamous cell carcinoma (SCC)-specific lncRNAs and investigate mechanisms that control their expression and function. METHODS:We studied expression patterns and f...

    journal_title:Gastroenterology

    pub_type: 杂志文章

    doi:10.1053/j.gastro.2018.02.018

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    更新日期:2018-06-01 00:00:00

  • Tissue transglutaminase does not affect fibrotic matrix stability or regression of liver fibrosis in mice.

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    journal_title:Gastroenterology

    pub_type: 杂志文章

    doi:10.1053/j.gastro.2011.01.040

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    更新日期:2011-05-01 00:00:00

  • Effects of caloric and noncaloric materials in fasting hyperbilirubinemia.

    abstract::Fasting hyperbilirubinemia (FHB) has previously been shown to be rapidly reversed by the ingestion of a mixed diet. This study examines the effect of carbohydrate, fat, amino acids, and noncaloric materials on FHB. After an initial fast of 15 to 39 hr, caloric and noncaloric materials were administered by mouth or vei...

    journal_title:Gastroenterology

    pub_type: 杂志文章

    doi:

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    更新日期:1975-02-01 00:00:00

  • Occurrence of specific secretory immunoglobulin A in bile after inoculation of Giardia lamblia trophozoites into rat duodenum.

    abstract::We studied the appearance of specific secretory immunoglobulin A (IgA) antibody in bile after inoculation of live Giardia lamblia trophozoites into rat intestine. Serial bile specimens collected before and after inoculation of trophozoites were assayed for IgA antibodies by indirect immunofluorescence. Secretory IgA a...

    journal_title:Gastroenterology

    pub_type: 杂志文章

    doi:

    authors: Loftness TJ,Erlandsen SL,Wilson ID,Meyer EA

    更新日期:1984-11-01 00:00:00

  • Patterns of Resistance-Associated Substitutions in Patients With Chronic HCV Infection Following Treatment With Direct-Acting Antivirals.

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  • Rectosigmoid motility and myoelectric activity in progressive systemic sclerosis.

    abstract::Colon motility and myoelectric slow wave activity were compared in 10 patients with progressive systemic sclerosis and 18 controls. Recordings were made in the rectosigmoid and rectum, 25-30 cm and 10-15 cm from the anal margin, respectively, during two 4-min baselines and in response to stepwise distention of the col...

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    doi:10.1016/0016-5085(89)91567-9

    authors: Whitehead WE,Taitelbaum G,Wigley FM,Schuster MM

    更新日期:1989-02-01 00:00:00

  • Isolation and morphologic characterization of bile duct epithelial cells from normal rat liver.

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    pub_type: 杂志文章

    doi:10.1016/0016-5085(89)91695-8

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    更新日期:1989-11-01 00:00:00

  • Protein precipitation by acetone for the analysis of polyethylene glycol in intestinal perfusion fluid.

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    journal_title:Gastroenterology

    pub_type: 杂志文章

    doi:

    authors: Buxton TB,Crockett JK,Moore WL 3rd,Moore WL Jr,Rissing JP

    更新日期:1979-04-01 00:00:00

  • JC virus DNA sequences are frequently present in the human upper and lower gastrointestinal tract.

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    pub_type: 杂志文章

    doi:10.1053/gast.2000.19269

    authors: Ricciardiello L,Laghi L,Ramamirtham P,Chang CL,Chang DK,Randolph AE,Boland CR

    更新日期:2000-11-01 00:00:00

  • Does alcohol directly stimulate pancreatic fibrogenesis? Studies with rat pancreatic stellate cells.

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    journal_title:Gastroenterology

    pub_type: 杂志文章

    doi:10.1016/s0016-5085(00)70148-x

    authors: Apte MV,Phillips PA,Fahmy RG,Darby SJ,Rodgers SC,McCaughan GW,Korsten MA,Pirola RC,Naidoo D,Wilson JS

    更新日期:2000-04-01 00:00:00

  • Restricted V(H) gene usage in lamina propria B cells producing anticolon antibody from patients with ulcerative colitis.

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    journal_title:Gastroenterology

    pub_type: 杂志文章

    doi:10.1053/gast.2001.25477

    authors: Inoue N,Watanabe M,Sato T,Okazawa A,Yamazaki M,Kanai T,Ogata H,Iwao Y,Ishii H,Hibi T

    更新日期:2001-07-01 00:00:00

  • Equivalent Accuracy of 2 Quantitative Fecal Immunochemical Tests in Detecting Advanced Neoplasia in an Organized Colorectal Cancer Screening Program.

    abstract:BACKGROUND & AIMS:Although different brands of fecal immunochemical tests (FITs) are used for colorectal cancer (CRC) screening, few studies have compared their accuracy in detecting advanced neoplasia. METHODS:We performed a large prospective cohort study within the Dutch national CRC screening program to evaluate 2 ...

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    pub_type: 杂志文章

    doi:10.1053/j.gastro.2018.07.021

    authors: Wieten E,de Klerk CM,van der Steen A,Ramakers CR,Kuipers EJ,Hansen BE,Lansdorp-Vogelaar I,Bossuyt PM,Dekker E,Spaander MCW

    更新日期:2018-11-01 00:00:00